EPS-CAF-00035

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-CAF-00035

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	191.3	3.2E-56	232	485	254

Status

Unreviewed

Ensembl Protein

ENSCAFP00000042451

UniProt Accession

J9P9L8;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1E

Gene Synonyms/Alias

PPM1E;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000030155	ENSCAFP00000042451	ENSCAFT00000048826

Organism

Canis familiaris

Functional Description

Protein Length

755

Protein Sequence
(FASTA)

MAGCSPEEKT YRRFLELFLG EFRGPCGGGE PEPEPEPESE PEPELVAAEA AEASVEDPGE 60

EAATVAATEE GEQEHEQDPE PEEEAVEEEA AAAAEGEEEE EAAAARGQSA VPPAPPQPQL 120

PPLPPLPRPL SERITREEVE GESLDLCLQQ LYKYNCPSFL AAALARATSD EVLQSDLSAH 180

YIPKETDGTE GTVEIETMKL ARSVFSKLHE ICCSWVKDFP LRRRPQLYYE TSIHAIKNMR 240

RKMEDKHVCI PDFNMLFNLE DQEEQAYFAV FDGHGGVDAA IYASIHLHVN LVRQEMFPHD 300

PAEALCRAFR VTDERFVQKA ARESLRCGTT GVVTFIRGNM LHVAWVGDSQ VMLVRKGQAV 360

ELMKPHKPDR EDEKQRIEAL GGCVVWFGAW RVNGSLSVSR AIGDAEHKPY ICGDADSAST 420

VLDGTEDYLI LACDGFYDTV NPDEAVKVVS DHLKENNGDS SMVAHKLVAS ARDAGSSDNI 480

TVIVVFLRDM NKAVNVSEES DWTENSFQGG QEDGGDDKEN HGECKRPWPQ HQCSAPADLG 540

YDGRVDSFTD RTSLSPGSQI NVLEDPGYLD LTQIEASKPH SAQFLSPIEM FGPGAPKKAN 600

PINELIMEKK SVQSSLPEQS GGAGEFPSFN LGSTGQQMYR MESLSPVCPR LEDEQFKFLG 660

KRVSRLSHLR YHYSKRWHGF RFNPKLYSFM SGQEPSHKIG TSLSSLIRSG KRNRMFRSFL 720

PWRQNIWKGY STNMMRKLRK SNDIPDPGLP WSYKI 755

Nucleotide Sequence
(FASTA)

ATGGCCGGCT GCAGCCCTGA GGAGAAAACT TACCGGCGCT TTCTGGAGCT ATTTCTGGGC 60

GAGTTTCGCG GACCGTGCGG TGGCGGCGAG CCCGAGCCGG AACCCGAACC CGAGTCGGAG 120

CCCGAGCCCG AACTGGTCGC GGCTGAGGCG GCCGAGGCTT CGGTCGAGGA CCCCGGGGAG 180

GAGGCGGCCA CCGTAGCCGC GACAGAGGAG GGGGAGCAAG AGCACGAACA AGACCCCGAG 240

CCCGAGGAGG AGGCGGTGGA GGAAGAGGCG GCGGCGGCGG CGGAGGGCGA GGAGGAGGAG 300

GAGGCGGCGG CAGCCCGGGG TCAGTCGGCC GTGCCGCCGG CGCCGCCGCA GCCCCAGCTG 360

CCGCCGCTGC CCCCGCTCCC GCGGCCGCTG TCGGAGCGCA TCACCCGCGA GGAGGTGGAG 420

GGCGAGAGCC TGGACCTGTG CCTGCAGCAG CTCTACAAAT ATAATTGCCC TTCCTTTCTG 480

GCTGCTGCTT TAGCCAGAGC CACATCAGAT GAAGTCCTTC AGAGTGATCT TTCTGCACAT 540

TATATCCCAA AGGAAACAGA TGGCACAGAA GGGACTGTGG AGATTGAGAC AATGAAATTG 600

GCCCGTTCGG TCTTCAGCAA ACTACACGAG ATTTGCTGCA GCTGGGTGAA AGACTTCCCT 660

CTCCGCAGGA GACCCCAGCT TTATTATGAG ACATCAATCC ATGCCATCAA AAACATGCGC 720

AGGAAAATGG AAGACAAACA TGTCTGCATT CCTGACTTTA ATATGCTCTT CAATCTTGAG 780

GACCAAGAAG AACAAGCTTA CTTTGCAGTG TTTGATGGCC ATGGGGGAGT GGATGCTGCT 840

ATTTATGCCT CCATTCACCT GCATGTTAAT TTAGTACGCC AGGAGATGTT CCCCCATGAT 900

CCTGCTGAGG CTCTGTGCCG AGCTTTTCGG GTCACTGATG AACGGTTTGT GCAGAAAGCA 960

GCCAGGGAGA GTTTAAGATG TGGGACTACA GGAGTGGTGA CTTTCATCAG AGGGAACATG 1020

CTTCATGTGG CCTGGGTTGG GGATTCCCAG GTCATGCTTG TGAGAAAAGG TCAAGCTGTT 1080

GAGCTAATGA AGCCGCACAA ACCGGACAGG GAGGATGAAA AGCAGCGAAT TGAGGCTCTT 1140

GGAGGTTGTG TAGTCTGGTT TGGTGCCTGG AGGGTGAATG GAAGTCTGTC GGTCTCCAGA 1200

GCTATTGGAG ACGCTGAACA TAAGCCATAT ATCTGTGGGG ATGCAGATTC TGCCTCTACT 1260

GTTTTGGATG GAACTGAAGA CTACCTCATT CTGGCCTGTG ATGGCTTCTA TGACACCGTG 1320

AACCCTGATG AGGCAGTGAA AGTTGTGTCT GACCATCTGA AGGAGAATAA TGGAGACAGT 1380

AGCATGGTTG CCCACAAATT AGTTGCATCA GCTCGTGATG CTGGGTCAAG TGATAACATC 1440

ACTGTTATTG TGGTATTCCT GAGGGACATG AACAAAGCTG TAAATGTTAG TGAGGAATCA 1500

GATTGGACAG AGAACTCTTT TCAAGGAGGG CAAGAAGATG GTGGGGATGA TAAGGAGAAT 1560

CATGGAGAGT GCAAACGCCC TTGGCCTCAG CACCAGTGCT CAGCACCAGC CGATCTAGGC 1620

TATGATGGGC GCGTGGATTC ATTCACTGAT AGAACTAGCC TGAGCCCAGG GTCCCAAATC 1680

AACGTGCTGG AAGACCCGGG CTACCTAGAT CTCACACAAA TAGAAGCAAG CAAACCTCAC 1740

AGTGCCCAGT TTTTGTCACC AATTGAGATG TTTGGTCCTG GTGCACCAAA GAAAGCAAAT 1800

CCTATTAATG AGCTAATAAT GGAGAAAAAA TCAGTTCAAT CATCATTGCC TGAACAGAGT 1860

GGTGGTGCTG GAGAGTTTCC CTCTTTTAAT TTGGGTTCAA CAGGGCAGCA GATGTACAGA 1920

ATGGAGAGCT TGTCTCCTGT CTGTCCTAGG TTGGAAGATG AACAGTTCAA ATTCCTGGGA 1980

AAGAGAGTTT CCAGATTGTC TCATTTACGC TATCATTATT CAAAGAGATG GCATGGATTC 2040

AGGTTTAATC CAAAGCTGTA TTCATTTATG TCTGGTCAAG AGCCTTCCCA CAAAATAGGC 2100

ACTAGTCTGT CCTCACTTAT TCGGAGTGGG AAGAGAAACA GAATGTTCAG AAGTTTTCTG 2160

CCATGGAGGC AAAATATTTG GAAAGGATAC AGTACAAACA TGATGAGGAA GCTCAGAAAG 2220

AGTAATGACA TTCCAGACCC AGGTCTCCCC TGGAGCTATA AAATATAA 2268

Domain Profile

S: 4     gvvsvngrrnemedavtsspnflkspekkdr..laffgvyDGhggsevakfcseklheil  61

         ++ +++++r++med++   p+f    + +d+   a+f+v+DGhgg ++a ++s +lh  l

Q: 232   SIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQeeQAYFAVFDGHGGVDAAIYASIHLHVNL  291

         567899**************99766555544459************************99

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdsklyvan  121

          ++         +  +al +aF  tde++  ++++  ++ ++G+t vv  i+++ l+va

Q: 292   VRQEM----FPHDPAEALCRAFRVTDERF--VQKAARESLRCGTTGVVTFIRGNMLHVAW  345

         99955....6788888999**********..7777788888*******************

S: 122   vGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdga.RvlGvLavsRalGd  180

         vGdS+++L r+g+avel + Hkp+redE++Rie+ gg v+ + ga Rv+G+L vsRa+Gd

Q: 346   VGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVV-WFGAwRVNGSLSVSRAIGD  404

         *************************************999.55899**************

S: 181   lylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvle.kkeaeqeaa  239

          + kpy+  + +  s+ l+  +++liLa+DG +d+v++ eav++v d+l+ ++ + + +a

Q: 405   AEHKPYICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVKVVSDHLKeNNGDSSMVA  464

         ************************************************9966778899**

S: 240   kkLvklalargskdnvsaivv  260

         +kLv+ a++ gs+dn+++ivv

Q: 465   HKLVASARDAGSSDNITVIVV  485

         *****************9997

Domain Sequence
(FASTA)

SIHAIKNMRR KMEDKHVCIP DFNMLFNLED QEEQAYFAVF DGHGGVDAAI YASIHLHVNL 60

VRQEMFPHDP AEALCRAFRV TDERFVQKAA RESLRCGTTG VVTFIRGNML HVAWVGDSQV 120

MLVRKGQAVE LMKPHKPDRE DEKQRIEALG GCVVWFGAWR VNGSLSVSRA IGDAEHKPYI 180

CGDADSASTV LDGTEDYLIL ACDGFYDTVN PDEAVKVVSD HLKENNGDSS MVAHKLVASA 240

RDAGSSDNIT VIVV 254

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>