EPS-CAF-00021

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-CAF-00021

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	62.6	4.3E-17	181	259	79

Status

Unreviewed

Ensembl Protein

ENSCAFP00000036528

UniProt Accession

J9NTP3;

Protein Name

Protein Synonyms/Alias

Gene Name

PTPMT1

Gene Synonyms/Alias

PTPMT1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000032426	ENSCAFP00000036528	ENSCAFT00000045058

Organism

Canis familiaris

Functional Description

Protein Length

275

Protein Sequence
(FASTA)

MEPGAGASGC AAERREAGPE ASAPEGPAAT AAPSREAADE WPPSSPSPSG LLSRPRPASL 60

GVGEARLPEA GGGRMAAGGL LEAGLARVLF YPTLLYTLFR GKVPGRAHRD WYHRIDPTVL 120

LGALPLRNMT RRLVQDENVR GVITMNEEYE TRFLCNSSKE WKKVGVEQLR LSTVDMTGVP 180

TLANLQKGVQ FALKYQSLGQ SVYVHCKAGR SRSATMVAAY LIQVYNWSPE EAVRAITKIR 240

SHIHIRSGQL EVLKEFHKEI TAGAAKDNTC HTSQT 275

Nucleotide Sequence
(FASTA)

ATGGAGCCCG GCGCGGGCGC CTCGGGCTGC GCCGCCGAGC GCCGAGAGGC CGGGCCCGAA 60

GCCTCGGCGC CGGAGGGGCC CGCGGCGACC GCGGCGCCTT CGCGGGAGGC GGCGGACGAG 120

TGGCCGCCCT CGTCCCCGTC GCCCTCGGGG CTCCTCTCGC GGCCGCGGCC CGCGAGCCTC 180

GGCGTGGGTG AGGCGCGGCT GCCTGAGGCC GGCGGCGGCA GGATGGCGGC CGGCGGGTTG 240

CTGGAGGCCG GCCTGGCCCG GGTGCTCTTC TACCCGACGC TGCTGTACAC CCTGTTCCGC 300

GGGAAGGTGC CGGGCCGGGC GCACCGCGAC TGGTACCACC GCATCGACCC CACGGTGCTG 360

CTGGGCGCGC TGCCGCTGCG GAACATGACG CGCCGGCTGG TTCAGGACGA GAACGTGCGC 420

GGGGTGATCA CCATGAACGA GGAATATGAG ACGCGGTTCC TGTGTAACTC CTCAAAGGAA 480

TGGAAGAAAG TAGGAGTCGA ACAGCTGCGG CTCAGCACAG TAGACATGAC TGGAGTCCCA 540

ACCTTGGCTA ACCTCCAGAA AGGAGTCCAG TTTGCTCTCA AGTACCAGTC GCTGGGCCAG 600

TCTGTCTACG TGCATTGTAA GGCTGGGCGC TCCAGAAGTG CCACTATGGT GGCAGCATAT 660

CTGATTCAGG TGTACAACTG GAGTCCAGAG GAGGCTGTAA GAGCCATCAC CAAGATCCGG 720

TCACACATCC ACATCAGATC TGGCCAGTTG GAAGTTCTCA AAGAGTTCCA CAAGGAGATT 780

ACTGCAGGGG CAGCAAAGGA TAACACTTGT CACACATCAC AGACGTGA 828

Domain Profile

S: 68    llqyfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAieavkrkr  127

          l  +++ ++f  + ++ g++v+vHC+aG sRSat+v aYL++v+++s ++A++a+ + r

Q: 181   TLANLQKGVQFALKYQSLGQSVYVHCKAGRSRSATMVAAYLIQVYNWSPEEAVRAITKIR  240

         4555666677777779999*****************************************

S: 128   psiepnegfleQLlelekk  146

         ++i  ++g+le L e+ k+

Q: 241   SHIHIRSGQLEVLKEFHKE  259

         ****************986

Domain Sequence
(FASTA)

TLANLQKGVQ FALKYQSLGQ SVYVHCKAGR SRSATMVAAY LIQVYNWSPE EAVRAITKIR 60

SHIHIRSGQL EVLKEFHKE 79

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR024950	; DUSP.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782

; DSPc; 1.

SMARTs

Prosites

PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.

Prints

Created Date

20-Feb-2013