EKS-CII-00034

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00034

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/GSK	443.8	2.2E-133	41	325	285

Status

Unreviewed

Ensembl Protein

ENSCINP00000003673

UniProt Accession

Q9NL43;

Protein Name

Protein Synonyms/Alias

Glycogen synthase kinase; Glycogen synthase kinase alpha/beta;

Gene Name

CiGSK

Gene Synonyms/Alias

CiGSK; Ci-GSK alpha/beta, gsk;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000001821	ENSCINP00000003673	ENSCINT00000003673

Organism

Ciona intestinalis

Functional Description

Protein Length

407

Protein Sequence
(FASTA)

MHGAPKTTLG NMKGSRDKES KITTVVATHG HGPDRPQEVA YTDTKVIGNG SFGVVYQARL 60

IESNEMVAIK KVLQDKRFKN RELQIMRKLD HCNIVRLRYF FYSSGDKKDE IYLNLVLDFV 120

PETVYRVARQ YSKSKQTIPI LYVKLYMYQL FRSLAYIHSQ GTCHRDIKPQ NLLLDPETAV 180

LKLCDFGSAK QLVRGEPNVS YICSRYYRAP ELIFGATDYT SSIDVWSAGC VLAELLLGQP 240

IFPGDSGVDQ LVEIIKVLGT PTRDQIREMN PNYTEFKFPQ IKAHPWSKVF RPRTPPEAIA 300

LCSRLLEYSP DNRISPLESC AHSFFDELRL PNTKLPNGRS LPPLFNFTDK ELSIKSPLNN 360

ILIPLHARNA NSAGSTGDYS MGNSIENNGS TSAIGAGGVI ATSAPQP 407

Nucleotide Sequence
(FASTA)

ATGCACGGAG CGCCCAAGAC GACTCTAGGC AACATGAAAG GTAGCAGAGA TAAAGAATCC 60

AAAATCACGA CAGTGGTCGC AACACACGGC CATGGACCCG ACCGCCCCCA AGAAGTTGCC 120

TATACCGACA CCAAAGTCAT TGGGAATGGC TCATTTGGTG TTGTATACCA AGCGAGGCTT 180

ATTGAAAGTA ACGAGATGGT GGCCATTAAG AAAGTCCTAC AGGACAAAAG ATTTAAAAAC 240

CGCGAGTTGC AGATTATGAG GAAGTTAGAC CACTGCAATA TTGTGAGGTT GCGTTACTTT 300

TTCTATTCCA GTGGAGACAA GAAAGATGAA ATTTACTTAA ATCTTGTGCT TGATTTCGTT 360

CCGGAAACTG TATATCGTGT AGCAAGACAG TACAGCAAAT CAAAGCAAAC TATTCCTATT 420

TTGTACGTCA AGCTTTACAT GTACCAGCTT TTCCGTAGCC TTGCATACAT TCATTCGCAG 480

GGGACATGCC ACAGGGACAT TAAGCCTCAA AATCTCCTTC TAGACCCTGA GACAGCTGTT 540

TTAAAGCTGT GCGACTTTGG AAGTGCCAAA CAACTGGTTC GCGGCGAACC AAATGTCTCT 600

TACATTTGTT CGCGGTACTA CAGAGCACCT GAGCTCATAT TTGGTGCCAC GGATTACACC 660

TCATCCATTG ATGTTTGGTC TGCTGGATGT GTGCTCGCTG AGTTGCTGCT TGGACAACCC 720

ATCTTCCCAG GAGACAGTGG AGTTGACCAA CTTGTTGAGA TCATCAAAGT CCTCGGCACA 780

CCAACAAGGG ACCAGATACG CGAGATGAAC CCCAACTATA CTGAGTTCAA GTTCCCGCAG 840

ATTAAAGCTC ATCCTTGGTC CAAAGTCTTC AGACCTCGAA CACCTCCAGA AGCGATAGCT 900

CTTTGCAGTC GTCTCCTTGA ATATTCTCCC GACAATCGCA TTTCTCCCCT CGAGTCGTGT 960

GCCCACAGTT TCTTTGACGA GTTGCGCTTA CCCAACACCA AGCTACCAAA CGGCCGGTCC 1020

CTTCCACCCC TGTTCAATTT CACGGACAAG GAGCTGTCAA TCAAGTCACC GCTGAACAAC 1080

ATACTTATTC CCCTCCACGC AAGGAACGCC AACTCTGCTG GATCCACAGG AGATTATAGC 1140

ATGGGAAACA GCATCGAAAA CAACGGCAGC ACTTCAGCAA TTGGGGCTGG TGGTGTAATC 1200

GCTACATCAG CGCCACAACC C 1221

Domain Profile

S: 1     leelkligsGsFgnVyqavlseesekevaiKkvlqdkklknlEleilrklkHknivrLly  60

         ++++k+ig+GsFg+Vyqa+l+e++e+ vaiKkvlqdk++kn+El+i+rkl+H+nivrL+y

Q: 41    YTDTKVIGNGSFGVVYQARLIESNEM-VAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRY  99

         5789**********************.*********************************

S: 61    ffsksaekkdkvylnlvleylPetlakvlrelkdkkkkldvlevklytyQlfrglaylhs  120

         ff++s +kkd++ylnlvl+++Pet+++v+r+++++k+++++l+vkly+yQlfr+lay+hs

Q: 100   FFYSSGDKKDEIYLNLVLDFVPETVYRVARQYSKSKQTIPILYVKLYMYQLFRSLAYIHS  159

         ************************************************************

S: 121   leivHrDiKPqNllvdeetgvlKlcDfGsakrleknepnvsYivsRyYRaPELllgakey  180

         ++ +HrDiKPqNll+d+et+vlKlcDfGsak+l+++epnvsYi+sRyYRaPEL++ga++y

Q: 160   QGTCHRDIKPQNLLLDPETAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDY  219

         ************************************************************

S: 181   ttkiDvWsagcvlaEllkgkvlfkgksakdqlelivkvlGtptkedikemnvkykekkfk  240

         t++iDvWsagcvlaEll+g+++f+g+s++dql++i+kvlGtpt+++i+emn++y+e+kf+

Q: 220   TSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTRDQIREMNPNYTEFKFP  279

         ************************************************************

S: 241   kikkvslakvlkkkedkeavdllkkilkyepkkRlsalellahpff  286

         +ik+++++kv++ ++++ea++l++++l+y+p +R+s+le +ah+ff

Q: 280   QIKAHPWSKVFRPRTPPEAIALCSRLLEYSPDNRISPLESCAHSFF  325

         *********************************************9

Domain Sequence
(FASTA)

YTDTKVIGNG SFGVVYQARL IESNEMVAIK KVLQDKRFKN RELQIMRKLD HCNIVRLRYF 60

FYSSGDKKDE IYLNLVLDFV PETVYRVARQ YSKSKQTIPI LYVKLYMYQL FRSLAYIHSQ 120

GTCHRDIKPQ NLLLDPETAV LKLCDFGSAK QLVRGEPNVS YICSRYYRAP ELIFGATDYT 180

SSIDVWSAGC VLAELLLGQP IFPGDSGVDQ LVEIIKVLGT PTRDQIREMN PNYTEFKFPQ 240

IKAHPWSKVF RPRTPPEAIA LCSRLLEYSP DNRISPLESC AHSFF 285

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>