EKS-CII-00267

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00267

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK2	503.0	1.4E-151	2	258	257

Status

Unreviewed

Ensembl Protein

ENSCINP00000004087

UniProt Accession

F6W6I5;

Protein Name

Protein Synonyms/Alias

Gene Name

camk2d

Gene Synonyms/Alias

camk2d;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000002022	ENSCINP00000004087	ENSCINT00000004087

Organism

Ciona intestinalis

Functional Description

Protein Length

477

Protein Sequence
(FASTA)

ILAEELGKGA FSVVKRCTHR SSKQDYAAKI INTKKLSSRD LQKLDREARI CRLLKHTNIV 60

RLHASIPEEG LHFLVFDLVT GGELFEDIVA REYYSEADAS HCMQQVLEAV YHCHKSGVIH 120

RDLKPENLLL ASKEKGALVK LADFGLAIEV NDDQPAWYGF AGTPGYLSPE VLRKEPYGKP 180

VDLWACGVIL YILLVGYPPF WDDDQNRLYA QIKDGAYDFP SPEWDTVTKE AKDLINQMLS 240

TKTSDRITAS DALRNPWICQ RDRVASHIHR QDTVDCLKTF NARRKLKGAI ITTMLATRNF 300

SRSSMSRNKE SNKEPQAQST VVRANSAVLK PTGENGLDLT AEEIKAKKLE VFHATEQLMQ 360

SINSRNFAAY SRFCSNDFTC FDPLSMGNLM HGNDFQKYYF ETAPKSEHLR KSSILNPHIV 420

LLGGDVAYIA YICLTQYIDG SGKPVSVQTE ETRIWNKVEG SWRNSHLHRS ESVTARK 477

Nucleotide Sequence
(FASTA)

ATTCTTGCAG AAGAATTGGG CAAAGGGGCA TTCAGTGTGG TCAAGAGATG CACCCACAGA 60

AGTTCCAAAC AGGATTACGC TGCTAAGATA ATTAATACGA AAAAACTAAG CAGTAGAGAT 120

CTTCAGAAAT TGGACAGGGA AGCACGAATT TGTCGACTAC TGAAGCACAC CAATATTGTG 180

AGGCTCCATG CAAGTATTCC AGAAGAGGGG CTCCATTTTC TAGTCTTTGA CTTGGTAACA 240

GGGGGTGAGT TGTTCGAGGA CATTGTAGCC CGCGAATACT ACAGTGAAGC TGATGCCAGT 300

CATTGCATGC AGCAGGTTTT AGAGGCAGTT TATCATTGTC ATAAATCGGG TGTGATTCAT 360

CGTGATTTAA AGCCTGAAAA CTTGCTCCTG GCAAGCAAAG AAAAAGGTGC TCTCGTGAAA 420

TTAGCTGACT TTGGCTTGGC TATTGAAGTC AATGATGATC AGCCTGCATG GTATGGTTTT 480

GCTGGCACAC CGGGGTATTT GTCACCTGAG GTTTTACGAA AGGAACCTTA TGGCAAACCT 540

GTTGATCTCT GGGCGTGTGG TGTAATCCTG TACATCCTCT TGGTTGGCTA CCCTCCTTTT 600

TGGGATGACG ACCAGAACCG ATTGTACGCT CAGATAAAAG ATGGTGCTTA CGATTTTCCG 660

TCACCAGAAT GGGATACTGT CACAAAAGAA GCAAAGGATC TCATTAACCA GATGCTTAGC 720

ACTAAAACAA GCGATCGAAT CACAGCCAGC GATGCTTTGC GCAACCCATG GATTTGCCAG 780

CGTGACAGAG TGGCTTCACA CATCCACAGG CAGGACACTG TGGATTGCTT GAAGACGTTC 840

AATGCAAGGA GAAAGTTAAA GGGAGCCATT ATCACCACCA TGTTAGCAAC CCGCAACTTT 900

TCTCGCAGTT CTATGTCCAG GAACAAGGAA TCAAACAAAG AACCGCAAGC CCAGTCCACA 960

GTTGTACGTG CCAACAGTGC TGTTCTCAAA CCCACTGGCG AAAATGGCTT AGATTTAACA 1020

GCAGAAGAAA TCAAGGCGAA GAAGTTGGAA GTCTTCCATG CAACAGAACA GCTCATGCAG 1080

TCGATAAATT CGCGAAACTT CGCTGCTTAT TCTCGATTTT GCTCGAACGA CTTCACCTGC 1140

TTTGATCCAC TTTCTATGGG AAATCTTATG CATGGAAACG ATTTTCAAAA ATACTACTTC 1200

GAGACTGCAC CAAAGAGTGA ACACCTGAGG AAGAGTTCCA TCCTTAATCC ACATATCGTT 1260

TTGCTGGGTG GCGATGTCGC ATACATTGCG TACATTTGCC TTACCCAGTA CATCGATGGC 1320

TCTGGAAAGC CTGTGTCCGT CCAAACCGAG GAGACGAGAA TCTGGAATAA AGTTGAGGGC 1380

TCATGGAGGA ACAGCCACCT GCATCGCTCG GAAAGCGTGA CAGCACGAAA GTAG 1434

Domain Profile

S: 3     lfeelgkgafsvvrrcvkvttgqeyaakiintkklsardhqklerearicrllkhpnivr  62

         l eelgkgafsvv+rc + ++ q+yaakiintkkls+rd qkl+rearicrllkh+nivr

Q: 2     LAEELGKGAFSVVKRCTHRSSKQDYAAKIINTKKLSSRDLQKLDREARICRLLKHTNIVR  61

         679*********************************************************

S: 63    lhdsiseegfhylvfdlvtggelfedivareyyseadashciqqilesvlhihqngvvhr  122

         lh si eeg h+lvfdlvtggelfedivareyyseadashc+qq+le+v h+h+ gv+hr

Q: 62    LHASIPEEGLHFLVFDLVTGGELFEDIVAREYYSEADASHCMQQVLEAVYHCHKSGVIHR  121

         ************************************************************

S: 123   dlkpenlllaskakgaavkladfglaievqgdqqawfgfagtpgylspevlrkdpygkpv  182

         dlkpenlllask kga vkladfglaiev+ dq aw+gfagtpgylspevlrk+pygkpv

Q: 122   DLKPENLLLASKEKGALVKLADFGLAIEVNDDQPAWYGFAGTPGYLSPEVLRKEPYGKPV  181

         ************************************************************

S: 183   dlwacgvilyillvgyppfwdedqhrlyqqikagaydfpspewdtvtpeakdlinkmlti  242

         dlwacgvilyillvgyppfwd+dq rly+qik gaydfpspewdtvt eakdlin+ml+

Q: 182   DLWACGVILYILLVGYPPFWDDDQNRLYAQIKDGAYDFPSPEWDTVTKEAKDLINQMLST  241

         ************************************************************

S: 243   npakritadealkhpwi  259

         + + rita++al++pwi

Q: 242   KTSDRITASDALRNPWI  258

         ****************8

Domain Sequence
(FASTA)

LAEELGKGAF SVVKRCTHRS SKQDYAAKII NTKKLSSRDL QKLDREARIC RLLKHTNIVR 60

LHASIPEEGL HFLVFDLVTG GELFEDIVAR EYYSEADASH CMQQVLEAVY HCHKSGVIHR 120

DLKPENLLLA SKEKGALVKL ADFGLAIEVN DDQPAWYGFA GTPGYLSPEV LRKEPYGKPV 180

DLWACGVILY ILLVGYPPFW DDDQNRLYAQ IKDGAYDFPS PEWDTVTKEA KDLINQMLST 240

KTSDRITASD ALRNPWI 257

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004683	; F:calmodulin-dependent protein kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR013543	; Ca/CaM-dep_prot_kinase-assoc.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF08332	; CaMKII_AD; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013