EKS-CII-00156

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00156

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PLK	339.4	1.2E-101	27	280	254

Status

Unreviewed

Ensembl Protein

ENSCINP00000026188

UniProt Accession

F6XLX0;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000002263	ENSCINP00000026188	ENSCINT00000026434

Organism

Ciona intestinalis

Functional Description

Protein Length

936

Protein Sequence
(FASTA)

MPHKVAKKLY NSHSDQMPPY GSTIAEYEVL NLIGRGAFAC VYRAKCRQSN RGVAIKMIDK 60

RSMRKSGMVS RVRSEVEIHA QLKHPSILEL HHCFEDADHV YLILELCMKG ELNRFLKSQG 120

NSLCEQQVRE FMVQIVEGML YLHAHGILHR DITLANMLLD DNCHIKIADF GLATRLALPT 180

DKHFTMCGTP NFISPEIATR SAHGLESDVW SLGCMFYTFL VGVPPFDTDA VKSTLNRVVL 240

GNFTIPENIS QQASDLITKM LRKDPQDRIS LSAVLDHPFM KPDTLKGREA SVDSGHATMT 300

TNSTNNYKSR RQPPRTRPIV ALPPQKLEPV LDIGSTYEES YDERRPAAKN GFGRPENTDT 360

RRQWASRTRD MPGNRPPMWR QPEDRGENPH DVRHVHGDGS WGQRTDSFTS GTLPSKPRSH 420

YSQVRQAALV VTRANRSRMT SPDTTTRYRG NSLTRRPCDP TICSTLQGEA FSLTKQNTNQ 480

DATNRTQSWR SPRQNSRQDA QACRLRATKT RAVARKQAHS KPQLNMYSKP PKPHHSVHSH 540

TSSNTRRAEA KSRDLPNINS CRLRTIRQKA KNSMVSILQN GEVCLEIVNS KTGKDIVTEV 600

LCVSDNGNSI KIFSPTTKEQ SGYILSKQPP IPPDSTNTYE KSTLPDKYHN KYKYLARFVQ 660

LVRSKTPKVT LFTKQAKCML MENAPEADLE ACFYNGAKVQ QSKGKTMIID QTGKLITLDS 720

QDLRRLPLDQ NCEAIANLTP EYQDMLTHAL TSRQKALDIE SAISVVEENS GNDSSYFPIT 780

VSRTPTRSPE PVSTPRTPDS LPTPSIAPTT SPSAAPPIHF TESVLSYRSS ATAMSRKRSV 840

PKHVFTPLAD SNQVSKTLEV PGVGRASHLC TGDIWVMYND RSQILMQSAT TTVLYSHPSG 900

RRERFGQSAR LPEYVKAKLS DLPSIVEMLV QAARES 936

Nucleotide Sequence
(FASTA)

ATGCCTCATA AAGTAGCAAA GAAGCTATAC AACTCTCATA GTGATCAAAT GCCCCCTTAT 60

GGAAGCACAA TTGCTGAGTA TGAAGTTCTT AACCTAATTG GACGTGGCGC TTTTGCTTGC 120

GTATACCGCG CAAAGTGCAG ACAGTCAAAC CGTGGTGTAG CGATCAAAAT GATCGATAAA 180

CGGAGCATGA GGAAGTCCGG GATGGTTTCT CGTGTCCGGA GCGAGGTTGA AATTCATGCC 240

CAGCTCAAGC ATCCTTCAAT ACTGGAGCTG CATCACTGTT TTGAAGATGC TGATCATGTT 300

TATCTCATCT TGGAGCTTTG CATGAAAGGA GAACTGAACC GATTTTTAAA AAGTCAAGGA 360

AATTCATTGT GTGAACAACA AGTGCGTGAA TTCATGGTGC AAATAGTAGA AGGAATGTTG 420

TATCTACATG CACATGGAAT TCTTCATCGT GACATAACCC TTGCCAATAT GCTGCTTGAT 480

GATAATTGCC ACATTAAAAT AGCTGATTTT GGGCTCGCAA CTCGCCTTGC TCTACCTACA 540

GATAAACACT TCACCATGTG TGGTACCCCA AACTTCATAT CTCCAGAGAT AGCAACTCGA 600

AGCGCGCATG GTTTAGAATC TGATGTATGG TCACTGGGCT GCATGTTTTA CACGTTTTTG 660

GTGGGCGTGC CTCCATTTGA CACTGACGCA GTTAAAAGCA CACTGAACCG CGTTGTGCTT 720

GGTAACTTCA CAATACCTGA GAATATTTCA CAACAAGCCA GTGACCTCAT CACTAAAATG 780

CTAAGGAAGG ATCCTCAAGA TCGTATCTCG CTCTCTGCTG TGCTGGACCA CCCATTCATG 840

AAACCAGACA CGCTAAAAGG TCGTGAGGCG TCAGTAGACA GTGGACATGC GACAATGACA 900

ACCAATTCAA CGAACAACTA CAAGTCGAGA AGGCAGCCGC CAAGAACGAG ACCAATCGTG 960

GCTTTACCGC CGCAGAAATT GGAACCTGTT CTGGACATAG GTTCGACCTA TGAGGAGTCT 1020

TACGATGAAC GACGACCGGC GGCGAAAAAC GGCTTCGGCC GGCCCGAGAA CACCGATACC 1080

CGGCGGCAGT GGGCGAGTCG GACCCGGGAC ATGCCGGGCA ATCGACCTCC AATGTGGCGG 1140

CAACCGGAAG ACCGCGGGGA AAACCCTCAT GACGTGCGAC ATGTCCACGG CGACGGGTCT 1200

TGGGGTCAAC GCACGGACTC GTTTACTAGC GGTACTCTGC CTTCCAAGCC ACGCAGTCAT 1260

TACAGTCAAG TTCGACAGGC AGCGCTCGTC GTTACCCGCG CGAACCGCAG TCGAATGACG 1320

TCACCGGATA CGACGACACG TTACAGGGGA AATTCCCTGA CGCGTCGACC ATGCGACCCG 1380

ACGATCTGTT CTACCCTCCA GGGGGAAGCT TTCAGCCTTA CCAAGCAAAA TACGAACCAG 1440

GATGCTACAA ATCGAACACA ATCATGGCGC AGTCCGCGGC AGAACAGCCG ACAGGATGCG 1500

CAAGCATGCC GATTACGCGC CACCAAAACC CGAGCGGTCG CACGAAAACA AGCACACTCA 1560

AAGCCACAAT TGAACATGTA CAGCAAACCT CCAAAGCCAC ACCACAGCGT TCATTCCCAC 1620

ACATCATCCA ATACAAGACG AGCGGAAGCG AAATCTCGCG ACCTTCCCAA CATTAACTCA 1680

TGCAGACTTC GCACAATTCG ACAAAAAGCC AAAAATTCCA TGGTCAGCAT ACTACAGAAT 1740

GGTGAGGTGT GTCTGGAAAT AGTGAACAGC AAAACAGGCA AAGATATTGT TACTGAAGTA 1800

CTGTGCGTCT CAGACAACGG AAATTCAATA AAGATATTTT CACCCACCAC CAAAGAACAA 1860

AGTGGATATA TATTATCCAA ACAACCACCC ATACCACCAG ACTCAACCAA TACATATGAG 1920

AAATCTACAT TACCTGACAA ATACCACAAC AAGTACAAAT ATCTAGCAAG GTTTGTGCAA 1980

TTGGTACGAT CTAAAACACC CAAGGTAACT CTGTTTACAA AGCAAGCAAA GTGCATGTTA 2040

ATGGAAAACG CACCGGAAGC CGACCTCGAA GCATGTTTTT ATAACGGCGC TAAGGTCCAA 2100

CAGAGCAAAG GCAAAACTAT GATAATCGAT CAGACCGGCA AGCTTATCAC ACTGGACAGC 2160

CAAGATTTGC GTAGATTACC ACTCGACCAA AACTGTGAAG CAATTGCTAA CCTCACCCCC 2220

GAGTACCAAG ATATGCTGAC TCATGCTCTG ACATCACGAC AGAAAGCTCT CGACATCGAG 2280

TCAGCAATTT CGGTGGTTGA GGAGAATTCG GGAAATGACT CGTCATATTT TCCTATAACT 2340

GTATCACGCA CTCCAACAAG AAGCCCCGAG CCTGTATCAA CACCTCGAAC CCCTGATAGT 2400

TTGCCGACAC CATCAATAGC TCCCACCACG TCTCCAAGCG CAGCACCCCC TATTCATTTT 2460

ACTGAGTCAG TTCTTTCATA TCGTTCTAGT GCTACAGCCA TGAGCAGGAA ACGAAGCGTG 2520

CCAAAGCATG TTTTCACTCC ACTGGCCGAC TCTAACCAGG TATCCAAGAC ATTGGAAGTC 2580

CCAGGTGTTG GTCGTGCCTC ACATTTATGC ACCGGTGATA TATGGGTTAT GTACAATGAT 2640

AGATCACAGA TATTAATGCA GTCAGCTACA ACTACTGTGC TCTACTCCCA CCCTTCCGGC 2700

CGCAGAGAAA GGTTCGGCCA GTCTGCTAGG TTGCCGGAAT ACGTGAAAGC CAAATTATCT 2760

GACCTACCTT CTATTGTTGA AATGCTTGTA CAGGCGGCTA GAGAAAGC 2808

Domain Profile

S: 1     yergkllGkGgfakcyelkdletkevfavkvvpksllakekqrekvekeieihrslkhkn  60

         ye+ +l+G+G+fa +y++k+ ++++ +a+k+++k ++ k+ + ++v++e+eih +lkh++

Q: 27    YEVLNLIGRGAFACVYRAKCRQSNRGVAIKMIDKRSMRKSGMVSRVRSEVEIHAQLKHPS  86

         78899*******************************************************

S: 61    ivklyeffedkenvylvlelcsrrslaellkrr.kaltepevryylrqivsglkylhekr  119

         i++l+++fed+++vyl+lelc +++l+++lk++ ++l e++vr ++ qiv+g++ylh +

Q: 87    ILELHHCFEDADHVYLILELCMKGELNRFLKSQgNSLCEQQVREFMVQIVEGMLYLHAHG  146

         *******************************9989*************************

S: 120   ilhrdlklgnlflneelevkigdfGlatrlekeeerkktlcGtPnyiaPevlskkghsle  179

         ilhrd++l+n++l+++ ++ki+dfGlatrl+ + +++ t+cGtPn+i+Pe++++++h+le

Q: 147   ILHRDITLANMLLDDNCHIKIADFGLATRLALPTDKHFTMCGTPNFISPEIATRSAHGLE  206

         ************************************************************

S: 180   vdiWslGcilytllvGkPPfetkelketyekikkaeyslPsslskeaksliakllkkePe  239

         +d+WslGc++yt+lvG PPf+t+++k+t+++++  ++++P+++s++a++li+k+l+k+P+

Q: 207   SDVWSLGCMFYTFLVGVPPFDTDAVKSTLNRVVLGNFTIPENISQQASDLITKMLRKDPQ  266

         ************************************************************

S: 240   erpsleevlkdefl  253

         +r+sl++vl+++f+

Q: 267   DRISLSAVLDHPFM  280

         ************98

Domain Sequence
(FASTA)

YEVLNLIGRG AFACVYRAKC RQSNRGVAIK MIDKRSMRKS GMVSRVRSEV EIHAQLKHPS 60

ILELHHCFED ADHVYLILEL CMKGELNRFL KSQGNSLCEQ QVREFMVQIV EGMLYLHAHG 120

ILHRDITLAN MLLDDNCHIK IADFGLATRL ALPTDKHFTM CGTPNFISPE IATRSAHGLE 180

SDVWSLGCMF YTFLVGVPPF DTDAVKSTLN RVVLGNFTIP ENISQQASDL ITKMLRKDPQ 240

DRISLSAVLD HPFM 254

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000959	; POLO_box_duplicated_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008266	; Tyr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00659	; POLO_box; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50078	; POLO_BOX; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.

Prints

Created Date

20-Feb-2013