EKS-CII-00026

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00026

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	342.9	1.1E-102	18	302	285

Status

Unreviewed

Ensembl Protein

ENSCINP00000026008

UniProt Accession

F7AZI8;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100182642

Gene Synonyms/Alias

LOC100182642;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000002325	ENSCINP00000026008	ENSCINT00000026254

Organism

Ciona intestinalis

Functional Description

Protein Length

354

Protein Sequence
(FASTA)

ANSCFLLFTD MASKSSRYEK IEFLGEGQFA TVYKAKDTKD DDRIVAVKKI KLGNRAEAKD 60

GINRTALREI KLLQELHHEN IIGLLDVFGQ KSNISLVFDF METDLEVIIK DMSIVLTQAH 120

IKSYMIMTLH GLEYLHSLWI LHRDLKPNNL LFDSHGVLKI GDFGLAKTFG SPSREYTHQV 180

VTRWYRSPEL LFGSRLYGVG VDMWAVGCIL AELLLRVPFL PGDSDLDQLS KIFETLGTPS 240

DAEWPGMKDL PDYICFKEFP GIPLSQCFSA ARDDLLELIS GLLRYNPGLR VTAVQALHFS 300

FFTNQPYPTA YQNLPLPASC SSVANKQPKA VAGTKRKRDN DTDSMAGLAK KLVF 354

Nucleotide Sequence
(FASTA)

GCAAACTCAT GTTTTCTTTT GTTTACAGAC ATGGCTAGCA AGTCCAGCAG ATATGAAAAG 60

ATTGAATTTC TTGGGGAAGG GCAGTTTGCT ACTGTGTATA AAGCTAAGGA TACGAAAGAT 120

GACGACAGAA TCGTGGCCGT GAAGAAAATT AAACTTGGAA ACAGAGCTGA GGCAAAAGAC 180

GGGATAAATA GAACCGCACT GAGAGAGATT AAGCTATTAC AGGAATTACA TCATGAAAAT 240

ATAATTGGGT TGTTGGATGT ATTTGGACAG AAATCAAATA TTAGTTTAGT TTTTGATTTC 300

ATGGAAACAG ATTTAGAAGT TATAATTAAA GACATGAGTA TTGTGCTAAC TCAAGCTCAT 360

ATTAAATCTT ATATGATAAT GACACTGCAT GGGTTAGAAT ACCTTCATTC ACTGTGGATA 420

TTACACCGAG ATTTGAAGCC AAATAATTTA CTGTTTGATT CGCACGGGGT TTTAAAGATT 480

GGTGATTTCG GTCTCGCGAA GACATTTGGA AGCCCAAGCC GTGAATATAC GCATCAGGTT 540

GTAACACGGT GGTATCGGAG TCCTGAGCTT CTATTTGGGT CAAGGTTATA TGGTGTGGGG 600

GTTGACATGT GGGCTGTAGG GTGTATACTC GCTGAACTTC TACTAAGAGT CCCATTTCTT 660

CCCGGTGACT CCGATTTAGA TCAATTGAGT AAAATATTTG AAACACTGGG AACGCCCAGT 720

GATGCAGAAT GGCCTGGGAT GAAAGATCTT CCGGATTATA TTTGTTTCAA GGAATTCCCA 780

GGCATCCCAC TTAGTCAATG CTTTTCTGCC GCAAGAGATG ATTTATTAGA ACTTATATCG 840

GGGTTACTGA GGTACAACCC TGGACTGAGG GTAACTGCAG TTCAAGCTTT ACATTTCTCC 900

TTCTTCACAA ACCAGCCATA CCCAACAGCT TACCAGAATC TACCTCTCCC AGCCTCATGT 960

TCTTCTGTAG CAAACAAACA ACCAAAAGCA GTTGCTGGGA CGAAACGAAA GCGCGACAAT 1020

GACACAGATT CAATGGCAGG CCTCGCTAAA AAACTTGTGT TCTGA 1065

Domain Profile

S: 1     yeklekigeGtygkvykakd.ketgevvAlKkirlekeke...gvpitalrEisllkelk  56

         yek+e +geG++++vykakd k+++++vA+Kki+l ++ e   g++ talrEi+ll+el+

Q: 18    YEKIEFLGEGQFATVYKAKDtKDDDRIVAVKKIKLGNRAEakdGINRTALREIKLLQELH  77

         99******************6778889********98764445*****************

S: 57    hknivkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglayl  116

         h+ni+ Ll+v+  +k+++ Lvf+f+e+dL+ ++k++++  l+++++ks++++ l+gl+yl

Q: 78    HENIIGLLDVFG-QKSNISLVFDFMETDLEVIIKDMSI-VLTQAHIKSYMIMTLHGLEYL  135

         ************.99***********************.*********************

S: 117   HsnkilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgak  176

         Hs +ilHRDlKp+NlL +++g+lk++DfGla++f+sp+++yt++vvT+wYr+PelL+g++

Q: 136   HSLWILHRDLKPNNLLFDSHGVLKIGDFGLAKTFGSPSREYTHQVVTRWYRSPELLFGSR  195

         ************************************************************

S: 177   eYstavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeykk  236

          Y+  vD+W+vgcilaell r p+++g+s+ dql++if++lgtps+++wp++++lp+y

Q: 196   LYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLSKIFETLGTPSDAEWPGMKDLPDYI-  254

         **********************************************************8.

S: 237   sfpkkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

          f++ +   l++ +++++++ l+l++ ll+++p  R++a +al+ ++f

Q: 255   CFKEFPGIPLSQCFSAARDDLLELISGLLRYNPGLRVTAVQALHFSFF  302

         89999999********9**************************99887

Domain Sequence
(FASTA)

YEKIEFLGEG QFATVYKAKD TKDDDRIVAV KKIKLGNRAE AKDGINRTAL REIKLLQELH 60

HENIIGLLDV FGQKSNISLV FDFMETDLEV IIKDMSIVLT QAHIKSYMIM TLHGLEYLHS 120

LWILHRDLKP NNLLFDSHGV LKIGDFGLAK TFGSPSREYT HQVVTRWYRS PELLFGSRLY 180

GVGVDMWAVG CILAELLLRV PFLPGDSDLD QLSKIFETLG TPSDAEWPGM KDLPDYICFK 240

EFPGIPLSQC FSAARDDLLE LISGLLRYNP GLRVTAVQAL HFSFF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013