EPS-CII-00031

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-CII-00031

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PTEN	243.9	1.1E-72	14	184	171

Status

Unreviewed

Ensembl Protein

ENSCINP00000004848

UniProt Accession

F6R4Z1;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100182434

Gene Synonyms/Alias

LOC100182434;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000002379	ENSCINP00000004848	ENSCINT00000004848

Organism

Ciona intestinalis

Functional Description

Protein Length

403

Protein Sequence
(FASTA)

KMSKIKRLVS KNKRRHIEDG YDLDLTYICP NILAMGFPAE KVEGFYRNNI DDVVRFLENK 60

HGSNYKVYNL CSERTYDTKK FHGRVAAYPF DDHNPPRFEL IKPFCEDLDQ WLGMHKDNIA 120

AIHCKAGKGR TGVMICCYLL HRRRFAKPSD ALHFYGLART NNMKGVTIPS QQRYVGYYWQ 180

LLQSSLTYKP KTLLLHSIQF ETLPLQHNAS LFFVVNQLKV KLYTSNPDLV IRGDDFLIFD 240

MPQPLPLCGD IKIEVFNKPV MRKDKVFHFW FNTFFVQHGA GSNLSETTPS TEKDMIVLPF 300

NKKELDRANK DEANKLFSAN FRVILIFSQM DALPTASKSP LLQAISGQKS SALQPSDPYD 360

QYSVGTPVNS SICSDTENED GSLSDTDDED DWDGIVDENV IRS 403

Nucleotide Sequence
(FASTA)

AAAATGTCGA AGATTAAACG TCTTGTAAGT AAAAACAAGC GTCGTCACAT TGAGGATGGA 60

TATGACCTTG ATCTCACTTA TATTTGCCCT AATATATTAG CCATGGGTTT CCCTGCTGAA 120

AAAGTGGAAG GATTTTACCG CAATAATATA GATGATGTTG TGCGTTTCTT GGAGAATAAA 180

CATGGAAGCA ATTATAAGGT TTATAATTTA TGTTCCGAGC GTACGTACGA CACCAAGAAG 240

TTCCACGGCC GTGTAGCAGC TTATCCATTC GATGATCATA ATCCACCAAG GTTCGAACTG 300

ATTAAGCCGT TTTGTGAAGA CCTTGATCAA TGGTTAGGCA TGCATAAGGA TAACATTGCT 360

GCCATCCATT GCAAAGCTGG TAAAGGTAGA ACAGGAGTCA TGATCTGCTG CTATCTCCTA 420

CACAGGCGTA GGTTCGCCAA GCCTTCCGAT GCACTTCATT TCTATGGCCT CGCAAGAACC 480

AATAACATGA AAGGTGTAAC CATCCCGTCC CAGCAGCGAT ACGTTGGCTA CTATTGGCAG 540

CTGCTTCAAT CCAGCTTAAC CTACAAACCA AAGACATTGC TGCTACACAG CATTCAGTTT 600

GAAACCCTCC CTTTGCAGCA CAATGCCAGT TTATTTTTCG TGGTAAACCA GTTGAAAGTG 660

AAGCTCTATA CTTCTAACCC AGACCTTGTG ATACGAGGAG ATGATTTCCT TATTTTCGAC 720

ATGCCGCAAC CTCTGCCTTT ATGTGGAGAC ATCAAGATTG AAGTCTTCAA TAAACCAGTC 780

ATGAGGAAAG ACAAAGTCTT CCACTTCTGG TTCAACACAT TCTTTGTACA GCATGGAGCG 840

GGTTCAAACC TCAGTGAGAC CACTCCTTCT ACGGAAAAAG ATATGATAGT GCTGCCATTC 900

AACAAGAAGG AGCTTGACCG TGCAAACAAA GATGAAGCAA ATAAACTCTT TTCTGCTAAC 960

TTCCGAGTGA TTCTCATCTT TAGTCAGATG GATGCTCTTC CCACCGCATC TAAGTCCCCT 1020

CTTCTTCAAG CAATATCGGG CCAGAAATCT TCGGCCCTTC AACCCAGTGA TCCATACGAC 1080

CAATACTCTG TCGGAACACC AGTGAATTCC TCCATATGTT CCGACACAGA GAACGAAGAT 1140

GGAAGTTTAT CGGATACTGA TGACGAGGAT GACTGGGATG GAATCGTGGA TGAAAATGTC 1200

ATCCGTTCA 1209

Domain Profile

S: 1     rrltedgfdldltyvteriiavsfPaeareevyrnnlrevvrlldskhrnkyklynlcse  60

         rr  edg+dldlty+ ++i+a++fPae+ e++yrnn+++vvr+l++kh  +yk+ynlcse

Q: 14    RRHIEDGYDLDLTYICPNILAMGFPAEKVEGFYRNNIDDVVRFLENKHGSNYKVYNLCSE  73

         6889********************************************************

S: 61    rrydltklnakvaefgiedlnaPaleklvsickeldeWlseddenvvvlhckggkgrlGv  120

         r yd++k++ +va ++++d+n+P +e ++++c++ld+Wl   ++n++++hck+gkgr+Gv

Q: 74    RTYDTKKFHGRVAAYPFDDHNPPRFELIKPFCEDLDQWLGMHKDNIAAIHCKAGKGRTGV  133

         ************************************************************

S: 121   ivcayllaseisakadealdtfgerrtredkvagvkqPsqrryvsyfsqllkg  173

         ++c yll+++ +ak  +al+++g  rt + k  gv++Psq+ryv y+ qll++

Q: 134   MICCYLLHRRRFAKPSDALHFYGLARTNNMK--GVTIPSQQRYVGYYWQLLQS  184

         ***************************9999..****************9975

Domain Sequence
(FASTA)

RRHIEDGYDL DLTYICPNIL AMGFPAEKVE GFYRNNIDDV VRFLENKHGS NYKVYNLCSE 60

RTYDTKKFHG RVAAYPFDDH NPPRFELIKP FCEDLDQWLG MHKDNIAAIH CKAGKGRTGV 120

MICCYLLHRR RFAKPSDALH FYGLARTNNM KGVTIPSQQR YVGYYWQLLQ S 171

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR014019	; Phosphatase_tensin-typ.
IPR014020	; Tensin_phosphatase_C2-dom.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782	; DSPc; 1.
PF10409	; PTEN_C2; 1.

SMARTs

Prosites

PS51182	; C2_TENSIN; 1.
PS51181	; PPASE_TENSIN; 1.
PS00383	; TYR_PHOSPHATASE_1; 1.

Prints

Created Date

20-Feb-2013