EKS-CII-00028

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00028

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	330.0	9.5E-99	36	324	289

Status

Unreviewed

Ensembl Protein

ENSCINP00000005172

UniProt Accession

F6XQX8;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100175205

Gene Synonyms/Alias

LOC100175205;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000002540	ENSCINP00000005172	ENSCINT00000005172

Organism

Ciona intestinalis

Functional Description

Protein Length

324

Protein Sequence
(FASTA)

MTSEQSHDAD EAPSARASQS SLHAEPTSSP WTNQRYHTLS EIGVGAYGVV FKAQDMQSDD 60

ENKFVAIKCV RVENSEQGMP LSTVREIALL RQLESCEHPN VVRLLDICAG HHSKRETQLM 120

LVFEYVDQDL DVFLKKCPDS GLEPEKVTDI MRQMLGGLDF LHSMRVVHRD MKPQNILITT 180

TGQVKIADFG LARIYSIDMA LTEVVVTLWY RSPEVLLLDS YATPVDIWSA GCIFAELFNR 240

RPLFRGTGDV NQLKKIFDFI GRPSEAEWPL NVAVPIDSFP PQPPRPPQKF VPSITEDAAD 300

FLMKLLVFDP GKRLTAQSAL QHKY 324

Nucleotide Sequence
(FASTA)

ATGACAAGTG AACAGAGTCA TGATGCAGAT GAAGCACCAA GTGCTCGTGC CAGTCAGTCA 60

TCCTTACATG CCGAACCTAC CAGCAGTCCA TGGACAAACC AGCGTTACCA TACACTATCT 120

GAGATTGGTG TTGGTGCTTA TGGTGTTGTG TTTAAGGCAC AAGACATGCA GAGTGATGAT 180

GAGAATAAGT TTGTGGCAAT AAAATGTGTT CGAGTGGAAA ATTCTGAGCA AGGTATGCCT 240

TTGAGTACGG TCCGTGAAAT AGCTTTACTG AGGCAGCTTG AGTCTTGTGA ACACCCTAAT 300

GTTGTCAGAT TACTTGACAT TTGTGCTGGC CACCATTCAA AACGTGAAAC ACAACTCATG 360

CTTGTGTTTG AATATGTTGA CCAGGATCTT GACGTGTTTT TAAAAAAATG CCCCGACTCT 420

GGATTAGAAC CGGAAAAAGT CACAGATATT ATGCGGCAAA TGTTGGGGGG TTTGGATTTC 480

CTTCATTCCA TGAGGGTCGT TCATCGAGAC ATGAAACCAC AAAATATTCT CATCACCACA 540

ACTGGTCAAG TTAAAATCGC AGATTTTGGT CTTGCCAGAA TTTACAGCAT TGATATGGCA 600

CTAACTGAAG TGGTAGTAAC TTTATGGTAT CGGTCACCAG AAGTTCTACT ACTTGACAGT 660

TACGCAACAC CAGTTGATAT TTGGAGCGCT GGTTGTATCT TTGCCGAGTT ATTTAATAGA 720

AGACCTTTAT TCCGGGGCAC CGGAGATGTG AATCAACTCA AGAAAATATT CGATTTCATT 780

GGTCGACCAA GTGAAGCAGA ATGGCCACTT AATGTTGCTG TTCCGATTGA TTCTTTCCCT 840

CCCCAACCAC CTAGACCTCC ACAAAAGTTT GTTCCTTCTA TCACTGAAGA TGCTGCTGAC 900

TTTTTAATGA AACTCCTTGT GTTTGATCCT GGTAAGAGAC TTACTGCACA GAGTGCATTG 960

CAACATAAAT AT 972

Domain Profile

S: 1     yeklekigeGtygkvykakdke...tgevvAlKkirlekekegvpitalrEisllkel..  55

         y++l++ig G+yg+v+ka+d +   ++++vA+K++r+e++++g+p +++rEi+ll++l

Q: 36    YHTLSEIGVGAYGVVFKAQDMQsddENKFVAIKCVRVENSEQGMPLSTVREIALLRQLes  95

         78999**************9652224568****************************988

S: 56    .khknivkLlevva....kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqll  110

          +h+n+v+Ll+++a    k++++l+Lvfe+++qdL  +lkk++ ++l++e+v  +++q+l

Q: 96    cEHPNVVRLLDICAghhsKRETQLMLVFEYVDQDLDVFLKKCPDSGLEPEKVTDIMRQML  155

         89***********999877779**************************************

S: 111   eglaylHsnkilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPe  170

          gl++lHs +++HRD+KpqN+Li+++g++k+aDfGlar +s ++  +t++vvTlwYr+Pe

Q: 156   GGLDFLHSMRVVHRDMKPQNILITTTGQVKIADFGLARIYSIDMA-LTEVVVTLWYRSPE  214

         *******************************************99.**************

S: 171   lLlgakeYstavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsk  230

         +Ll + +Y t vDiWs+gci+ael++r+plf+g+ +++ql++if+ +g pse++wp

Q: 215   VLLLD-SYATPVDIWSAGCIFAELFNRRPLFRGTGDVNQLKKIFDFIGRPSEAEWPLNVA  273

         ***87.6**************************************************999

S: 231   lpeykksfpkkkkkklkekvkklkekaldllekllaldpkkRisakealqhky  283

         +p    sfp+++++  ++ v++++e+a d+l kll +dp kR++a++alqhky

Q: 274   VPID--SFPPQPPRPPQKFVPSITEDAADFLMKLLVFDPGKRLTAQSALQHKY  324

         9984..6********************************************98

Domain Sequence
(FASTA)

YHTLSEIGVG AYGVVFKAQD MQSDDENKFV AIKCVRVENS EQGMPLSTVR EIALLRQLES 60

CEHPNVVRLL DICAGHHSKR ETQLMLVFEY VDQDLDVFLK KCPDSGLEPE KVTDIMRQML 120

GGLDFLHSMR VVHRDMKPQN ILITTTGQVK IADFGLARIY SIDMALTEVV VTLWYRSPEV 180

LLLDSYATPV DIWSAGCIFA ELFNRRPLFR GTGDVNQLKK IFDFIGRPSE AEWPLNVAVP 240

IDSFPPQPPR PPQKFVPSIT EDAADFLMKL LVFDPGKRLT AQSALQHKY 289

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013