EKS-CII-00115

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00115

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PKC	430.6	2.0E-129	240	508	269

Status

Unreviewed

Ensembl Protein

ENSCINP00000006222

UniProt Accession

F6PPJ1;

Protein Name

Protein Synonyms/Alias

Gene Name

CIN.17402

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000003055	ENSCINP00000006222	ENSCINT00000006222

Organism

Ciona intestinalis

Functional Description

Protein Length

582

Protein Sequence
(FASTA)

RDIVKMSIDA GSHQILAKVY YSGHAFSLHL EHTIQMEELF TMVRLNCNFP DAQVFTLKWM 60

DDEGDPCTIS SQLELSEALR LYRHNNETVL LFHIFLGIPV EPGLLCPGEH KLYRHGARRW 120

YKLKRILRQI KKPKHPRIPI ESGPILDSGD SQDSKQFHPR FCYNECNCIL TMSPQIFKQN 180

LKQLLLHIPP SFCLSNYRSY LVVTPYVLCK QTPIYTKYKQ TSASSDQASP NAPGFGLKDF 240

EMLKVIGRGS YAKVLLVKLK STDKMYAMKV IKKELVTDEE DIDWVQTEKH VFETASNYPF 300

LVGLHSCFQT PERLFFVIEY VNGGDLMFHM QRQRKLPEEH ARFYAAEIVL ALHFLHEKGI 360

IYRDLKLDNV LLDSDGHIKL TDYGMCKEGI RKGVNTSTFC GTPNYIAPEI LRGEDYDFSV 420

DWWALGVLMF EMMAGRSPFD IVGMTDNPEQ NTEDYLFQVI LEKVIRIPRS LSVKASSVLK 480

GFLNKIPVDR LGCNHESGFQ DILDHQFFRT IDWDLLQSRQ VVPPYKPNIE DDLGLDNFDK 540

QFTQEPVQLT PTEATVIGKI DQADFEGFEY INPLLMTSDV AV 582

Nucleotide Sequence
(FASTA)

AGAGACATAG TTAAAATGTC CATAGACGCT GGTTCACATC AAATATTGGC GAAGGTATAT 60

TACAGTGGTC ATGCATTCTC ACTTCACCTG GAACATACAA TACAAATGGA GGAGTTATTT 120

ACAATGGTGC GATTGAATTG TAACTTTCCC GATGCTCAAG TTTTTACTTT AAAGTGGATG 180

GATGATGAGG GAGACCCATG CACCATATCT TCACAGCTTG AATTATCAGA AGCGCTGAGG 240

TTGTACAGGC ATAACAACGA AACTGTTTTA CTTTTCCATA TATTTCTTGG TATTCCTGTG 300

GAACCTGGTC TATTGTGTCC AGGAGAACAC AAGTTGTACA GGCACGGTGC GCGAAGGTGG 360

TACAAGTTAA AACGGATATT ACGGCAGATA AAGAAACCAA AACATCCAAG AATTCCTATC 420

GAAAGTGGAC CAATATTAGA TTCAGGTGAC AGCCAAGACA GTAAGCAATT TCACCCTAGA 480

TTTTGCTATA ATGAATGTAA CTGCATTTTA ACAATGTCGC CCCAGATTTT CAAACAAAAC 540

TTAAAACAAC TACTACTGCA TATACCTCCT TCATTCTGCT TGTCAAATTA TCGAAGCTAT 600

TTAGTTGTCA CACCTTATGT GTTGTGTAAA CAAACACCAA TATATACAAA ATATAAACAA 660

ACCTCGGCAA GCTCAGACCA AGCGAGTCCA AATGCTCCCG GGTTTGGCTT GAAAGACTTT 720

GAGATGCTTA AGGTGATAGG TAGAGGGAGC TACGCTAAAG TTTTACTGGT CAAGTTAAAA 780

TCTACGGACA AAATGTATGC TATGAAGGTA ATAAAGAAAG AGTTAGTGAC TGATGAAGAA 840

GATATAGATT GGGTGCAAAC AGAGAAACAT GTTTTTGAAA CTGCCTCAAA TTATCCTTTT 900

CTTGTCGGCC TTCATTCTTG TTTTCAGACA CCAGAGCGTT TATTTTTCGT CATTGAATAT 960

GTTAATGGTG GAGACTTAAT GTTCCATATG CAACGTCAGC GTAAACTACC CGAAGAACAT 1020

GCAAGATTTT ACGCAGCGGA AATTGTCCTA GCATTGCATT TCTTGCATGA GAAAGGAATC 1080

ATATACAGAG ATTTGAAACT AGATAATGTT TTGCTGGACA GCGATGGACA TATCAAGCTA 1140

ACTGACTACG GGATGTGCAA AGAGGGAATA AGGAAAGGTG TCAACACGTC AACTTTCTGT 1200

GGGACGCCCA ACTACATCGC ACCTGAGATT CTACGTGGAG AGGATTATGA TTTCTCCGTG 1260

GATTGGTGGG CACTAGGTGT CCTCATGTTT GAAATGATGG CTGGCCGAAG TCCGTTCGAT 1320

ATTGTTGGAA TGACCGATAA TCCAGAACAA AATACTGAAG ATTATCTTTT CCAGGTTATT 1380

CTAGAAAAAG TGATTCGAAT CCCACGGTCT CTGTCTGTCA AAGCTTCATC TGTGTTGAAA 1440

GGCTTCTTAA ACAAGATACC AGTGGACAGG TTAGGCTGCA ACCACGAAAG TGGTTTCCAA 1500

GATATTCTTG ATCATCAATT CTTTCGCACA ATTGATTGGG ATCTTTTGCA ATCGAGACAA 1560

GTGGTTCCCC CATATAAACC TAACATAGAG GATGACCTGG GATTGGATAA TTTCGACAAA 1620

CAGTTTACCC AGGAACCTGT ACAACTAACA CCCACTGAGG CGACTGTTAT TGGGAAAATA 1680

GATCAAGCAG ATTTTGAAGG GTTTGAATAC ATTAACCCAC TTCTAATGAC GAGTGATGTT 1740

GCTGTGTGA 1749

Domain Profile

S: 1     fellkvlGkGsfgkvllaelkktdelyaikvlkkdvvlqdddveltlvekrvlalaskkp  60

         fe+lkv+G+Gs++kvll++lk+td++ya+kv+kk++v++++d++++++ek+v+++as+ p

Q: 240   FEMLKVIGRGSYAKVLLVKLKSTDKMYAMKVIKKELVTDEEDIDWVQTEKHVFETASNYP  299

         899*********************************************************

S: 61    flvqlfscfqtedrlffvleyvnGGdlmfhiqkarklkeerarfyaaeiilalkflhekg  120

         flv l+scfqt +rlffv+eyvnGGdlmfh+q++rkl+ee+arfyaaei+lal+flhekg

Q: 300   FLVGLHSCFQTPERLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEIVLALHFLHEKG  359

         ************************************************************

S: 121   iiyrdlkldnvlldaeGhikladfGlckeeilegkttstfcGtPdyiaPeilkeeeygks  180

         iiyrdlkldnvlld++Ghikl+d+G+cke+i +g +tstfcGtP+yiaPeil++e+y++s

Q: 360   IIYRDLKLDNVLLDSDGHIKLTDYGMCKEGIRKGVNTSTFCGTPNYIAPEILRGEDYDFS  419

         ************************************************************

S: 181   vdwwalGvllyemlagqsPfe.........gededelfesilekevlyPkslskeaveil  231

         vdwwalGvl++em+ag+sPf+         +++ed+lf++ilek +++P+sls++a+++l

Q: 420   VDWWALGVLMFEMMAGRSPFDivgmtdnpeQNTEDYLFQVILEKVIRIPRSLSVKASSVL  479

         *****************************99*****************************

S: 232   kglltkdpekrlGvk.eegeedikehaff  259

         kg+l+k p +rlG++ e+g +di +h+ff

Q: 480   KGFLNKIPVDRLGCNhESGFQDILDHQFF  508

         **************6699**********9

Domain Sequence
(FASTA)

FEMLKVIGRG SYAKVLLVKL KSTDKMYAMK VIKKELVTDE EDIDWVQTEK HVFETASNYP 60

FLVGLHSCFQ TPERLFFVIE YVNGGDLMFH MQRQRKLPEE HARFYAAEIV LALHFLHEKG 120

IIYRDLKLDN VLLDSDGHIK LTDYGMCKEG IRKGVNTSTF CGTPNYIAPE ILRGEDYDFS 180

VDWWALGVLM FEMMAGRSPF DIVGMTDNPE QNTEDYLFQV ILEKVIRIPR SLSVKASSVL 240

KGFLNKIPVD RLGCNHESGF QDILDHQFF 269

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR000270	; OPR_PB1.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00564	; PB1; 1.
PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00666	; PB1; 1.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013