EKS-CII-00154

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00154

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	239.7	2.6E-71	753	1007	255

Status

Unreviewed

Ensembl Protein

ENSCINP00000009476

UniProt Accession

F6WPV3;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100186012

Gene Synonyms/Alias

LOC100186012;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000004591	ENSCINP00000009476	ENSCINT00000009476

Organism

Ciona intestinalis

Functional Description

Protein Length

1104

Protein Sequence
(FASTA)

MFHGDEQNVA TDVLASDSTR NKALRGKQLG VVSSFLNSFE HNQSFPMLPK NKKENRLAKG 60

LNKFTGKEIN ACTFSQDHLA NFNPADFPSV DLEKSFSSCI SKSSSRPHSR LSLGGSWSFS 120

SFINASDKIN PSDIKPINKA VFTIDAETSQ ILTANTNACI MFGYNGGFVN VKLTNLLKKP 180

SPGKPGKEAL LRDIHDVEGN EVVIAGKVME AVTKQGDVFA VSVWARKVEA NTEQPRCLVI 240

LQPVVRVVGK FQFNQQGDIL SCDDKFGHIH GYSDNTLLSK LKLQQLMPSY EMPTSSRISK 300

GVRKQQVTST TLDGQKIPIL VYIINQTESD TDVIYSANVW YFTDINGILV CHPCGKIKQI 360

NTNFSLALMG YTASEMCNKN IRDVLPDISS SAEPCSIKLD ISDDEVALVK ACSEDRTPNE 420

QFSATLIEKL SENETLQTSS CEPFEMISNA TAGNQQVSSF THIDFTLSEK QQSTADHINS 480

LLSGSCSESL GSDVDHNGSN IPYKHDLEGN SSWVELTLNE GNPSNAKDKL SQINAALNGS 540

LHSQPTVKDK TRSPDSAVHS SSETTESSST QENKGSTKSS FSDYHSRDGS PAHVFKSSAN 600

TSQLANHPKP NALSKTINIT STPIDGLLRS ESRMKSTLDL PLGIFSGQLR HKNNTLIPVT 660

YEIQNDENGQ LFYVRISFTT NYSHDPNQTL SSSFNSTLPS LNASAVSGML DYSLGAAIKQ 720

AAEQRNGNVS HEIETPEGNE EWNAMQGKFK EYYDVIRTIG NGAFGFVRMA KRRIDGKKVI 780

VKFIRKEKVL DDCWVDDYER EATIPLEISL LFKFNHPHIV EVVEFFENEN FFSMIMPTHG 840

TQGFDLFEFI DREPKLDEAL ASYIFRQVVS AVNYLHQQGV VHRDIKDENV IIDECFHCKL 900

IDFGSAAFFE DGKKFSTFCG TIEYCSPEVL LGNSYKGPEL EMWALGVTLY TLVFGENPFL 960

TAEDTIEAIL KPPNRLSDEL MFIIQWLLQP VPEHRCTMYD LLEDPWLNII IDPKEYNWED 1020

VVPSAGQKDV SYNGAIKPKM DDDCVEDFDS DDNEPLANQV KCWVNEHKKF GLKHGKMDPS 1080

GLDKDENIFP LTRCLENINL NHSI 1104

Nucleotide Sequence
(FASTA)

ATGTTCCATG GAGATGAGCA AAATGTGGCC ACTGATGTAT TAGCTTCAGA TTCTACGAGA 60

AACAAAGCTT TGAGGGGCAA ACAACTTGGA GTTGTTTCAT CTTTTCTAAA TTCATTTGAA 120

CATAATCAAT CATTCCCAAT GTTACCAAAA AACAAAAAGG AGAACAGACT TGCCAAAGGA 180

TTGAATAAGT TTACAGGAAA AGAGATAAAT GCTTGTACAT TTTCCCAAGA TCATCTCGCA 240

AATTTCAACC CTGCTGATTT TCCTTCAGTT GATTTGGAAA AATCTTTTTC TTCCTGTATT 300

TCTAAAAGCA GCTCCAGACC ACACTCAAGA TTATCATTAG GCGGATCATG GTCTTTCAGC 360

AGTTTTATAA ACGCATCAGA CAAAATCAAC CCTAGTGATA TTAAGCCAAT AAACAAAGCA 420

GTGTTCACCA TAGATGCTGA AACTTCTCAG ATCTTAACAG CGAACACGAA TGCTTGCATT 480

ATGTTTGGAT ATAATGGAGG TTTTGTGAAT GTGAAACTAA CGAACTTGTT AAAGAAACCG 540

TCTCCCGGCA AACCTGGAAA AGAAGCTCTT TTACGTGATA TACATGATGT GGAGGGGAAT 600

GAGGTGGTCA TTGCTGGCAA AGTTATGGAA GCAGTGACAA AACAAGGCGA TGTATTCGCA 660

GTATCAGTGT GGGCACGTAA GGTTGAAGCA AACACTGAAC AACCTCGATG TCTCGTCATC 720

TTGCAACCAG TTGTTCGGGT GGTTGGGAAG TTTCAATTCA ATCAACAGGG TGACATATTA 780

TCTTGTGATG ATAAATTCGG CCACATTCAT GGATACAGTG ACAATACATT GTTGTCTAAA 840

TTGAAGTTGC AACAACTGAT GCCTTCATAT GAAATGCCAA CTTCTTCGCG AATAAGCAAG 900

GGTGTACGGA AACAGCAAGT TACAAGTACG ACCTTAGATG GTCAAAAAAT ACCAATCTTG 960

GTTTACATCA TTAATCAAAC AGAATCTGAT ACTGACGTGA TCTACTCAGC AAATGTGTGG 1020

TATTTTACCG ACATCAACGG AATCCTTGTA TGTCATCCTT GTGGAAAGAT AAAACAGATC 1080

AACACCAACT TTTCACTTGC TCTCATGGGA TATACTGCCA GTGAAATGTG CAATAAGAAT 1140

ATAAGAGATG TGTTGCCGGA CATTTCCTCC TCAGCGGAAC CATGTAGCAT CAAACTCGAT 1200

ATAAGCGATG ATGAAGTTGC TTTGGTGAAG GCATGTAGTG AAGACAGAAC ACCAAACGAA 1260

CAGTTTTCAG CCACACTTAT AGAAAAGCTT TCAGAGAATG AAACTTTGCA AACTTCAAGC 1320

TGTGAACCAT TTGAAATGAT CTCGAACGCT ACTGCAGGAA ATCAACAAGT GAGCAGTTTT 1380

ACTCACATTG ATTTTACGTT GTCTGAAAAA CAACAAAGTA CGGCTGACCA CATCAATTCT 1440

TTGCTATCTG GAAGTTGCTC TGAATCTCTT GGTTCTGATG TTGATCATAA TGGTTCAAAT 1500

ATTCCATACA AACATGACTT AGAGGGCAAC AGTTCATGGG TGGAACTGAC GTTGAACGAA 1560

GGAAATCCTT CAAATGCAAA AGATAAATTG TCTCAGATAA ATGCTGCGTT GAATGGAAGT 1620

TTACATTCAC AACCAACAGT CAAAGATAAA ACTAGGAGTC CAGATTCAGC CGTTCACTCG 1680

TCTTCAGAAA CAACAGAATC TTCATCGACC CAGGAAAATA AAGGATCAAC AAAATCTTCG 1740

TTCTCAGATT ATCATTCACG TGATGGTTCA CCTGCTCATG TGTTCAAATC ATCCGCGAAT 1800

ACATCACAAC TTGCCAATCA CCCGAAACCT AACGCACTCT CAAAGACGAT CAATATAACG 1860

TCCACACCCA TTGATGGCTT GCTAAGATCA GAATCACGAA TGAAATCAAC TTTGGATCTT 1920

CCACTTGGTA TTTTCAGTGG TCAACTAAGA CACAAGAACA ATACCTTAAT ACCTGTTACG 1980

TATGAAATCC AAAATGATGA AAATGGTCAA TTGTTTTATG TTCGAATAAG TTTTACAACA 2040

AATTACTCCC ATGATCCCAA CCAAACATTA AGCAGCAGTT TCAACTCAAC ACTTCCTTCA 2100

TTAAATGCTT CTGCAGTTAG TGGTATGCTC GATTATTCAC TGGGTGCTGC TATAAAGCAA 2160

GCAGCAGAGC AGCGAAACGG AAATGTTTCA CATGAAATTG AAACACCGGA GGGCAATGAA 2220

GAGTGGAACG CAATGCAAGG AAAGTTCAAA GAGTATTATG ATGTCATAAG GACAATTGGA 2280

AACGGAGCGT TTGGTTTTGT TCGAATGGCA AAGAGAAGAA TAGATGGTAA AAAGGTTATT 2340

GTAAAATTCA TCAGAAAAGA GAAAGTCCTG GATGATTGCT GGGTGGATGA TTATGAAAGA 2400

GAAGCAACTA TTCCACTGGA AATATCTCTG CTTTTCAAGT TCAATCATCC ACACATTGTA 2460

GAAGTTGTGG AGTTTTTTGA GAACGAGAAT TTCTTCAGCA TGATAATGCC AACGCACGGA 2520

ACACAAGGAT TTGATTTATT TGAATTTATT GACCGTGAAC CAAAGTTGGA TGAAGCTCTT 2580

GCAAGTTATA TATTCCGTCA GGTTGTTTCT GCTGTCAACT ATTTACACCA ACAAGGTGTA 2640

GTTCATCGAG ATATCAAAGA TGAAAATGTC ATTATTGATG AATGTTTCCA CTGTAAACTG 2700

ATTGATTTTG GAAGTGCTGC GTTCTTTGAA GATGGTAAAA AGTTTTCAAC ATTTTGTGGA 2760

ACCATAGAAT ACTGCTCTCC TGAAGTTCTT CTCGGTAACA GCTATAAGGG TCCGGAGTTG 2820

GAGATGTGGG CACTTGGTGT AACTCTATAC ACGCTGGTTT TTGGTGAAAA CCCCTTTTTG 2880

ACCGCAGAAG ATACAATTGA AGCGATTTTA AAACCTCCAA ATCGATTGTC AGATGAATTA 2940

ATGTTTATAA TACAATGGCT ACTTCAACCT GTACCCGAGC ACAGATGCAC AATGTACGAT 3000

CTATTAGAAG ACCCTTGGTT AAATATTATA ATCGACCCGA AGGAGTATAA CTGGGAAGAT 3060

GTGGTCCCTT CAGCAGGCCA AAAAGATGTA TCTTACAACG GTGCAATTAA ACCCAAAATG 3120

GATGATGATT GTGTTGAAGA TTTTGATTCT GACGATAATG AACCACTAGC TAATCAAGTA 3180

AAGTGTTGGG TGAATGAGCA TAAGAAGTTT GGATTAAAAC ATGGAAAAAT GGACCCATCT 3240

GGTTTGGATA AAGATGAAAA CATTTTTCCA CTTACACGAT GCTTGGAAAA TATAAACCTT 3300

AATCATTCCA TTTAA 3315

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.......seeslekikrEieilk  53

         y++++t+G+g+fg V++ak++  ++kv+vK+i+k+k+       ++e   +i  Ei++l

Q: 753   YDVIRTIGNGAFGFVRMAKRRIDGKKVIVKFIRKEKVlddcwvdDYEREATIPLEISLLF  812

         899*********************************999999988888899*********

S: 54    klkhpniikllevietkkklylvle.y.asggeLfdyieekgrlkekearklfkqlvsav  111

         k++hp+i++++e++e+++++ +++  + ++g +Lf+ i ++ +l+e  a+ +f+q+vsav

Q: 813   KFNHPHIVEVVEFFENENFFSMIMPtHgTQGFDLFEFIDREPKLDEALASYIFRQVVSAV  872

         ************************94313455****************************

S: 112   kYlhskgivHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkg  171

         +Ylh++g+vHrD+K eN+++d+  + k++DFG a++f++gk+++tfcG+++Y++Pe+l g

Q: 873   NYLHQQGVVHRDIKDENVIIDECFHCKLIDFGSAAFFEDGKKFSTFCGTIEYCSPEVLLG  932

         ************************************************************

S: 172   kkYegpkvDvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrk  231

         ++Y+gp++++W+lGv+Ly+lv+g+ Pf ++      e + +  l+ p+ ls+el+ +++

Q: 933   NSYKGPELEMWALGVTLYTLVFGENPFLTA------EDTIEAILKPPNRLSDELMFIIQW  986

         ***************************999......566677788999************

S: 232   lLvvdpekRatieeilkhewl  252

         lL+  pe+R+t+ ++l+++wl

Q: 987   LLQPVPEHRCTMYDLLEDPWL  1007

         ********************7

Domain Sequence
(FASTA)

YDVIRTIGNG AFGFVRMAKR RIDGKKVIVK FIRKEKVLDD CWVDDYEREA TIPLEISLLF 60

KFNHPHIVEV VEFFENENFF SMIMPTHGTQ GFDLFEFIDR EPKLDEALAS YIFRQVVSAV 120

NYLHQQGVVH RDIKDENVII DECFHCKLID FGSAAFFEDG KKFSTFCGTI EYCSPEVLLG 180

NSYKGPELEM WALGVTLYTL VFGENPFLTA EDTIEAILKP PNRLSDELMF IIQWLLQPVP 240

EHRCTMYDLL EDPWL 255

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013