EKS-CII-00014

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00014

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/RAD53	313.0	1.3E-93	204	470	267

Status

Unreviewed

Ensembl Protein

ENSCINP00000010261

UniProt Accession

F6WMB2;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100175326

Gene Synonyms/Alias

LOC100175326;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000004987	ENSCINP00000010261	ENSCINT00000010261

Organism

Ciona intestinalis

Functional Description

Protein Length

524

Protein Sequence
(FASTA)

IMEDTNDERP KEKNASSSVE SDKEKMRSPA SLPASQEKVS SSSGTGTSSG NTVSSADTVP 60

TQEITDSQGV ELEPVWGVLH SMQPEFYSLN LRDEQYTFGR ANSCDYCFDI KTIKSTSRYK 120

HYSKRHFAIR RVKLEDETYQ VFIEDFGGQN GVYVNGVKIP SGRKQTIKTS DEIGIAYNNF 180

NVFLFIDKEK DSDLEVSDEF SKKYITHKLL GKGACGQVWE VWERFCAGKF AVKIISKTYL 240

SVSPSSKDVI KEADILRKLS HPCIIGVHDV VDLPQNLYIV LEFAKGGELF KRLEKGGKLP 300

EKIAKLYFFQ MLSAVKYLHD NEITHRDLKP ENILLMSTEE PCLIKITDFG MSRLVEEKSL 360

MKTLAGTPSY LAPEIIKQHM GLGKGYTKQV DLWSLGVILY VCLVAFPPFS AELTKTGQSI 420

DEQILSANYS FQNQPWSTVS NDAKNLVSSL LVLNANDRLT TSAAVAHPWL QDSEMIRTAN 480

SLMSTVETSL EMLPQTINLP SSAEKRCHTP NSSAEEPTAK LSKC 524

Nucleotide Sequence
(FASTA)

ATAATGGAAG ACACCAATGA CGAAAGACCA AAAGAGAAAA ATGCTTCATC GTCTGTAGAG 60

TCTGATAAAG AAAAGATGAG ATCACCTGCT TCTCTACCTG CGAGTCAAGA GAAAGTTTCA 120

TCATCATCTG GCACCGGTAC TTCGTCAGGA AATACGGTTT CAAGCGCGGA TACTGTTCCT 180

ACACAGGAGA TCACAGATTC ACAAGGTGTT GAATTGGAAC CTGTGTGGGG GGTGTTGCAC 240

TCCATGCAAC CAGAGTTTTA TTCCTTGAAT TTAAGAGATG AACAATACAC ATTTGGCCGG 300

GCAAACTCAT GTGATTATTG CTTTGATATT AAGACCATAA AAAGCACAAG CAGATACAAA 360

CATTATAGCA AACGACACTT TGCTATTAGA AGAGTGAAGT TAGAAGACGA AACTTACCAA 420

GTCTTTATAG AGGATTTTGG AGGACAAAAT GGTGTTTATG TTAATGGAGT AAAAATACCA 480

TCCGGAAGGA AACAAACTAT TAAAACATCT GATGAAATTG GGATCGCGTA CAATAACTTC 540

AACGTATTTC TTTTTATTGA TAAAGAAAAA GATTCTGATC TAGAAGTTTC TGATGAGTTT 600

TCAAAGAAGT ACATCACTCA TAAGTTGCTT GGCAAAGGCG CATGTGGTCA AGTTTGGGAG 660

GTGTGGGAAA GATTCTGTGC TGGAAAATTT GCTGTGAAGA TCATCAGCAA GACATATTTG 720

TCTGTATCAC CCTCAAGTAA AGATGTTATT AAAGAAGCAG ATATACTAAG GAAGCTGAGT 780

CACCCTTGTA TAATAGGTGT ACATGATGTG GTAGACCTGC CACAAAACTT GTACATTGTT 840

CTTGAGTTTG CAAAAGGTGG AGAATTGTTT AAGAGGCTTG AAAAAGGTGG AAAACTGCCG 900

GAGAAAATTG CGAAGCTTTA TTTCTTCCAG ATGCTTTCAG CTGTAAAGTA TCTGCATGAC 960

AATGAGATTA CACACAGAGA CCTAAAACCA GAAAATATTC TCCTAATGTC AACGGAGGAG 1020

CCTTGTCTTA TAAAGATTAC TGATTTTGGA ATGTCTAGAC TAGTGGAGGA AAAGAGCCTT 1080

ATGAAAACAC TCGCAGGGAC ACCTTCATAT CTTGCCCCTG AAATTATAAA GCAGCATATG 1140

GGTCTTGGTA AAGGGTACAC AAAACAAGTT GATTTATGGA GTCTTGGAGT GATTCTGTAT 1200

GTTTGTCTCG TTGCATTTCC ACCTTTCAGT GCCGAACTGA CCAAAACTGG ACAATCTATC 1260

GATGAACAAA TATTGTCAGC AAATTACAGT TTCCAGAACC AACCCTGGTC CACTGTATCA 1320

AATGATGCCA AAAACCTTGT CTCCAGTCTT CTTGTACTTA ATGCAAATGA CAGGTTAACT 1380

ACTAGCGCAG CTGTAGCACA TCCTTGGCTG CAAGATTCAG AGATGATACG CACTGCTAAT 1440

TCACTTATGT CGACAGTGGA AACATCATTG GAAATGTTGC CCCAAACCAT AAATTTACCA 1500

AGTTCTGCAG AAAAGCGTTG CCATACTCCG AATTCTTCAG CTGAAGAACC CACTGCCAAA 1560

CTTTCAAAAT GTTAA 1575

Domain Profile

S: 1     yilskelGkGafgkvklayekktgkkvavkilskrksirssreikkakeveeeveilkkl  60

         yi++k lGkGa+g+v ++ e+  + k+avki+sk       +   ++k+v +e++il+kl

Q: 204   YITHKLLGKGACGQVWEVWERFCAGKFAVKIISKTY----LSVSPSSKDVIKEADILRKL  259

         7999******************************99....334456789***********

S: 61    shPnivklkdvfeeeeskylvlelvegGelldkvvakkllkedlskllfkqlltavkylh  120

         shP+i+ ++dv++ ++  y+vle+ +gGel++++ +   l e+++kl+f+q+l+avkylh

Q: 260   SHPCIIGVHDVVDLPQNLYIVLEFAKGGELFKRLEKGGKLPEKIAKLYFFQMLSAVKYLH  319

         ************************************************************

S: 121   ekgiihrDlkPeniLlsekeedvlvkitDfGlakvlgevslmktlCGtpsyvaPevlvkk  180

         +++i+hrDlkPeniLl + ee++l+kitDfG++++++e+slmktl Gtpsy+aPe++ ++

Q: 320   DNEITHRDLKPENILLMSTEEPCLIKITDFGMSRLVEEKSLMKTLAGTPSYLAPEIIKQH  379

         *********************************************************987

S: 181   g..raeytskvDiWslGvvlfvilsGypPfseeltq..vslkeqilkgkyafieekwkki  236

             ++yt++vD+WslGv+l+v+l  +pPfs elt+  +s++eqil+++y f+++ w+++

Q: 380   MglGKGYTKQVDLWSLGVILYVCLVAFPPFSAELTKtgQSIDEQILSANYSFQNQPWSTV  439

         534589**************************98763379********************

S: 237   seeakdlikklLvvdPeerlsieealnhpWl  267

         s++ak+l+++lLv++ ++rl+++ a+ hpWl

Q: 440   SNDAKNLVSSLLVLNANDRLTTSAAVAHPWL  470

         ******************************7

Domain Sequence
(FASTA)

YITHKLLGKG ACGQVWEVWE RFCAGKFAVK IISKTYLSVS PSSKDVIKEA DILRKLSHPC 60

IIGVHDVVDL PQNLYIVLEF AKGGELFKRL EKGGKLPEKI AKLYFFQMLS AVKYLHDNEI 120

THRDLKPENI LLMSTEEPCL IKITDFGMSR LVEEKSLMKT LAGTPSYLAP EIIKQHMGLG 180

KGYTKQVDLW SLGVILYVCL VAFPPFSAEL TKTGQSIDEQ ILSANYSFQN QPWSTVSNDA 240

KNLVSSLLVL NANDRLTTSA AVAHPWL 267

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000253	; FHA_dom.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR008984	; SMAD_FHA_domain.

Pfam

PF00498	; FHA; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00240	; FHA; 1.
SM00220	; S_TKc; 1.

Prosites

PS50006	; FHA_DOMAIN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013