EKS-CII-00172

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00172

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IKK	360.0	7.2E-108	20	305	286

Status

Unreviewed

Ensembl Protein

ENSCINP00000011687

UniProt Accession

F7A8T7;

Protein Name

Protein Synonyms/Alias

Gene Name

ikk-epsilon

Gene Synonyms/Alias

ikk-epsilon;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000005640	ENSCINP00000011687	ENSCINT00000011687

Organism

Ciona intestinalis

Functional Description

Protein Length

797

Protein Sequence
(FASTA)

MNPHPAHNSS PIRSTLNYVW STTEILGQGA TGFVFKGREK KTGQEYAIKV FNSLNYMARS 60

LEARRREFEV LRKVDHKNVV RLFSVEEELT TKHDVIIMEL CPNGSLYSML DDPENLYGLP 120

ESEFHRVLSH ITAGMKHLHD KGIVHRDLKP GNIMRSLDDD GTAVYKLTDF GAARELGDDE 180

QFMSLYGTEE YLHPDIYERA VLRKHAGKMF SATVDLWSLG VTLYHVATGM LPFRPYGGAR 240

RNKDVMYRIT TEKPSGVISG VQHSERGSIE WSRELPKTCR LSHGFKKIFT VVLSGILECN 300

PHKIWTFDRY FAEVEDILSK KVINVFSVPN AMLHKVYISP EKTLVSFQEA VAELTEVRSS 360

KQLLLLDGEQ FEMEQFVPVK SYPHTTPEHP LILFSSDIND FQAITIPHTC KPPKVKPSLS 420

LDNDSSLAKV CSSTLFDIRK SVSYLLLVQI LIRLSVKWFV CYLKSRVVKL KLLRSNLQCK 480

VDCLRTALEI FEEHYQRETS LLTVITNLVT SPPEVNELKL YFTQITEKAK ILRQIRTEFD 540

QLNESTNQFD KLIIQEEIPS SIFVDEGSQT NDRLEERMKV ASEKSREISR LFKTHKKIRR 600

LSHSDDQLHK FEKQRLAEVC EASVTLFTDK SVPGCKRLHK ESINWFSNMN EYQKKLWNCE 660

TRIMRLSDRC QEQEESIRTL QRVYRDKLSL VESILKENAK PLSAASLPGP NLNVVQPSIA 720

VPSSWPNSID NPRSSRQRQL KQLRQGLIEA KNSLNEVRCE VQTGSEILKK LSSLTANRNC 780

ASPETPSRPC VPMRTND 797

Nucleotide Sequence
(FASTA)

ATGAACCCCC ATCCTGCCCA CAACTCTTCT CCCATTAGAA GCACCCTCAA CTATGTGTGG 60

TCGACCACTG AGATATTGGG GCAGGGGGCG ACAGGATTTG TGTTCAAAGG CCGGGAGAAG 120

AAAACTGGGC AGGAATATGC CATCAAGGTA TTCAATTCTC TCAACTACAT GGCACGCAGT 180

CTTGAAGCAC GGAGAAGGGA ATTTGAAGTT TTAAGAAAAG TTGATCATAA GAATGTTGTG 240

AGACTTTTCA GTGTGGAAGA AGAGTTGACA ACAAAGCACG ATGTAATAAT TATGGAGTTA 300

TGTCCCAACG GTAGTTTGTA CTCCATGCTG GATGATCCTG AAAATCTCTA TGGACTACCC 360

GAGTCGGAAT TCCATCGTGT ATTGAGCCAT ATAACTGCTG GTATGAAACA CCTTCACGAC 420

AAAGGTATTG TACACAGAGA TCTTAAACCT GGTAATATCA TGCGTTCCCT CGATGACGAT 480

GGCACTGCTG TGTACAAACT TACGGACTTT GGGGCAGCGA GAGAACTGGG AGATGATGAG 540

CAGTTCATGT CGCTCTATGG AACAGAGGAA TATTTGCACC CAGACATATA CGAGAGAGCT 600

GTTCTAAGAA AACATGCGGG TAAAATGTTT TCCGCAACTG TTGACCTTTG GAGTTTGGGA 660

GTTACTCTAT ACCATGTTGC TACCGGCATG CTCCCATTTC GTCCTTATGG TGGCGCTAGA 720

CGTAACAAAG ACGTGATGTA TAGGATTACA ACAGAAAAAC CAAGTGGTGT AATATCTGGG 780

GTCCAACATT CAGAAAGGGG AAGTATTGAA TGGAGTCGAG AACTGCCCAA GACGTGCCGA 840

CTGTCACATG GCTTTAAGAA AATTTTCACG GTTGTGCTTT CCGGTATCCT TGAATGCAAC 900

CCCCACAAAA TTTGGACGTT TGATCGTTAC TTTGCTGAAG TAGAAGACAT CCTGAGCAAA 960

AAAGTAATCA ACGTATTTAG CGTGCCCAAC GCCATGCTAC ATAAGGTTTA CATCAGTCCA 1020

GAAAAAACCT TGGTTTCGTT CCAAGAGGCG GTGGCTGAAC TGACAGAGGT TCGCTCCAGC 1080

AAACAACTTC TTCTGTTGGA TGGGGAACAG TTTGAGATGG AGCAATTCGT TCCCGTTAAG 1140

AGTTACCCCC ATACAACCCC TGAACACCCT CTTATCTTGT TCAGTTCTGA TATCAATGAT 1200

TTCCAAGCGA TAACTATACC TCACACATGC AAACCTCCAA AGGTGAAACC TTCGCTCTCA 1260

CTTGATAATG ACTCAAGTTT AGCGAAAGTT TGTTCGAGTA CGTTGTTTGA TATTCGAAAG 1320

TCAGTCAGTT ACCTGCTGCT TGTGCAAATC CTTATTCGTC TCAGTGTAAA GTGGTTTGTA 1380

TGTTATTTAA AATCTCGTGT TGTCAAATTA AAACTTCTCC GAAGCAATCT CCAATGCAAA 1440

GTAGATTGTC TGCGTACTGC ACTGGAAATA TTTGAAGAAC ATTACCAGCG AGAGACATCT 1500

TTACTGACAG TGATCACAAA TTTAGTGACC AGCCCTCCCG AGGTCAATGA ACTTAAGTTA 1560

TATTTCACTC AAATCACAGA GAAGGCGAAA ATTTTAAGAC AGATCCGCAC GGAATTTGAT 1620

CAGCTCAATG AATCTACGAA TCAGTTTGAT AAACTGATCA TCCAAGAAGA GATCCCAAGC 1680

TCCATCTTCG TGGATGAGGG ATCGCAAACC AACGACCGCC TCGAAGAGCG GATGAAAGTT 1740

GCTTCTGAAA AATCGAGAGA GATTAGCCGA CTTTTTAAAA CACACAAAAA AATCAGAAGA 1800

TTATCGCATA GTGATGATCA ACTCCATAAG TTTGAAAAAC AACGACTCGC AGAAGTCTGT 1860

GAAGCTTCTG TCACTCTTTT CACCGATAAA AGCGTCCCTG GGTGTAAACG GTTGCACAAA 1920

GAATCGATTA ATTGGTTCAG TAATATGAAT GAGTACCAGA AGAAGTTATG GAATTGTGAG 1980

ACTCGTATCA TGAGATTGAG TGACAGGTGT CAAGAACAGG AAGAATCCAT TCGTACGTTA 2040

CAACGAGTAT ATCGAGACAA ATTATCATTA GTTGAGTCAA TTTTAAAAGA AAATGCAAAA 2100

CCTTTATCAG CAGCATCGCT ACCTGGCCCC AATCTTAATG TTGTCCAGCC TAGTATAGCA 2160

GTTCCTTCAT CATGGCCTAA CTCCATTGAC AATCCCCGGT CTTCCCGGCA AAGGCAATTG 2220

AAACAGCTTC GTCAAGGTTT AATTGAGGCC AAAAACAGCC TCAATGAAGT CAGATGCGAA 2280

GTACAAACTG GTTCTGAAAT TTTAAAAAAA CTCAGTTCAT TAACAGCAAA CCGAAACTGT 2340

GCTTCCCCTG AAACACCTTC CAGACCATGC GTGCCAATGA GAACTAATGA TTGA 2394

Domain Profile

S: 1     WelkelLGeGafgnvikarnkktgekiavkvikeessl.rprevqvrelevlrklnhkni  59

         W ++e+LG+Ga+g v+k+r+kktg+++a+kv+++  ++ r  e + re+evlrk++hkn+

Q: 20    WSTTEILGQGATGFVFKGREKKTGQEYAIKVFNSLNYMaRSLEARRREFEVLRKVDHKNV  79

         9*********************************99876999******************

S: 60    vklvdveeelnlasarlkvlvleyCsgGdlrkvLeepenayGLkesevlvvLsdvvaglr  119

         v+l+ veee   +++++ v+++e+C  G+l+++L++pen yGL+ese+  vLs+++ag++

Q: 80    VRLFSVEEE---LTTKHDVIIMELCPNGSLYSMLDDPENLYGLPESEFHRVLSHITAGMK  136

         *********...899*********************************************

S: 120   yLrenkivhRDlkPenivllkgedgksiykltDlGaareldddekvvslvGteeYlaPel  179

         +L++++ivhRDlkP+ni++   +dg  +ykltD+Gaarel dde+++sl+GteeYl+P++

Q: 137   HLHDKGIVHRDLKPGNIMRSLDDDGTAVYKLTDFGAARELGDDEQFMSLYGTEEYLHPDI  196

         ************************************************************

S: 180   ye........qkkytatvDlWsiGvllyeaitGslPflpfegprr....lykkitkkpak  227

         ye         k ++atvDlWs+Gv+ly+++tG+lPf+p++g rr    +y+++t+kp++

Q: 197   YEravlrkhaGKMFSATVDLWSLGVTLYHVATGMLPFRPYGGARRnkdvMYRITTEKPSG  256

         ********999********************************999**************

S: 228   aiagteka.ngevefssslPlsaslssglqeklekllanllevdeekrw  275

         +i+g++++  g++e+s +lP +++ls+g+++ ++ +l+ +le +++k w

Q: 257   VISGVQHSeRGSIEWSRELPKTCRLSHGFKKIFTVVLSGILECNPHKIW  305

         *******999************************************998

Domain Sequence
(FASTA)

WSTTEILGQG ATGFVFKGRE KKTGQEYAIK VFNSLNYMAR SLEARRREFE VLRKVDHKNV 60

VRLFSVEEEL TTKHDVIIME LCPNGSLYSM LDDPENLYGL PESEFHRVLS HITAGMKHLH 120

DKGIVHRDLK PGNIMRSLDD DGTAVYKLTD FGAARELGDD EQFMSLYGTE EYLHPDIYER 180

AVLRKHAGKM FSATVDLWSL GVTLYHVATG MLPFRPYGGA RRNKDVMYRI TTEKPSGVIS 240

GVQHSERGSI EWSRELPKTC RLSHGFKKIF TVVLSGILEC NPHKIW 286

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>