EKS-CII-00013

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00013

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/YANK	358.9	1.5E-107	24	279	256

Status

Unreviewed

Ensembl Protein

ENSCINP00000012550

UniProt Accession

F6ZFM9;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100187220

Gene Synonyms/Alias

LOC100187220;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000006077	ENSCINP00000012550	ENSCINT00000012550

Organism

Ciona intestinalis

Functional Description

Protein Length

346

Protein Sequence
(FASTA)

MGTKSSKNED GDDDPSADVG FNDFEVLRSI GKGSFGKVCI VRRKKTENEV YAMKYMNKLS 60

SWKHGAIDHV LRELEILSTL RHQFLVNLWF TFQDEEDIFM VSDLLMGGDL RYHIQRHVHF 120

TFDDVRIYFC ELALVLDYLR NKHIIHRDIK PDNILLDERG HLHLTDFNIA TVLNDEHPCA 180

KSFAGTKPYY DITAPEIFNS SSGYDYAVDW WSLGVTMYEV LRHKRPFNIG SDTTNEEVTA 240

LHNDGSISFP VDWGQPIMNL FFKLFKVDPT KRIQSFESLI SEEFCQNMEA DDVMRLKGQP 300

TFQPSQKELN YDPTFELEEM IIESNPLHKK KQRIQKLKKN SQKKKS 346

Nucleotide Sequence
(FASTA)

ATGGGAACGA AATCGTCCAA AAACGAAGAT GGCGACGACG ATCCCAGCGC TGACGTCGGG 60

TTCAACGACT TCGAGGTCCT TCGTTCGATC GGAAAGGGAA GTTTCGGCAA AGTTTGCATC 120

GTGAGACGCA AGAAGACGGA GAATGAGGTT TACGCGATGA AATATATGAA CAAACTATCA 180

TCATGGAAAC ATGGGGCCAT CGATCATGTG TTAAGGGAGC TGGAAATATT GTCGACGCTA 240

CGTCATCAGT TCCTGGTGAA TTTGTGGTTT ACTTTTCAGG ATGAAGAAGA TATCTTCATG 300

GTCAGCGATC TTCTCATGGG TGGCGACCTC CGTTACCACA TTCAACGACA CGTGCATTTC 360

ACTTTCGATG ATGTTCGAAT ATATTTCTGT GAACTAGCTC TGGTACTTGA CTATTTGCGC 420

AACAAACATA TTATACACAG AGACATCAAA CCCGATAATA TCCTCCTTGA CGAGCGAGGC 480

CATCTTCATC TAACGGACTT TAACATCGCT ACTGTACTTA ATGATGAACA TCCGTGTGCA 540

AAGTCATTCG CTGGAACAAA GCCTTATTAT GACATCACAG CCCCCGAAAT CTTTAATTCA 600

TCGTCTGGTT ACGATTACGC TGTGGATTGG TGGTCACTAG GGGTCACCAT GTACGAAGTA 660

TTGCGACACA AACGTCCGTT TAACATTGGA TCTGACACAA CGAATGAAGA AGTTACAGCT 720

TTACACAACG ATGGCTCAAT CTCGTTCCCT GTCGATTGGG GGCAACCTAT CATGAACTTG 780

TTTTTTAAGC TTTTTAAAGT CGACCCTACA AAACGAATCC AAAGTTTCGA AAGTTTAATT 840

TCGGAAGAAT TTTGTCAAAA TATGGAAGCT GATGATGTCA TGAGGTTAAA AGGTCAACCC 900

ACGTTTCAGC CATCGCAAAA AGAGTTGAAC TACGACCCGA CCTTTGAACT CGAGGAAATG 960

ATCATCGAGT CGAACCCACT GCATAAAAAG AAACAAAGGA TCCAAAAACT TAAGAAAAAT 1020

TCCCAGAAGA AGAAGTCG 1038

Domain Profile

S: 1     fqilraiGkGsfGkvcivqkrdtk.klyalkymnkqkcierdevrnvlrelellqelehp  59

         f++lr+iGkGsfGkvciv++++t+  +ya+kymnk    +++++  vlrele+l+ l h

Q: 24    FEVLRSIGKGSFGKVCIVRRKKTEnEVYAMKYMNKLSSWKHGAIDHVLRELEILSTLRHQ  83

         89*****************99997369*********************************

S: 60    flvnlwysfqdeedlfmvvdlllGGdlryhlqqnvkfsedtvklyicelalaleylqeqk  119

         flvnlw++fqdeed+fmv+dll+GGdlryh+q++v+f+ d v++y celal l+yl++++

Q: 84    FLVNLWFTFQDEEDIFMVSDLLMGGDLRYHIQRHVHFTFDDVRIYFCELALVLDYLRNKH  143

         ************************************************************

S: 120   iihrdikpdnilldekGhahltdfniatvlkdee.ratslaGtkpym...apevfasyle  175

         iihrdikpdnillde+Gh hltdfniatvl+de+  a s+aGtkpy    ape+f+s

Q: 144   IIHRDIKPDNILLDERGHLHLTDFNIATVLNDEHpCAKSFAGTKPYYditAPEIFNS---  200

         *******************************98735789*******54459****98...

S: 176   keaGysfevdwwslGvvayellrgrrpyeiksstaveeivnlfktesvkypstwskelva  235

          ++Gy+++vdwwslGv++ye+lr +rp++i s t+ ee++ l +  s+++p  w + +++

Q: 201   -SSGYDYAVDWWSLGVTMYEVLRHKRPFNIGSDTTNEEVTALHNDGSISFPVDWGQPIMN  259

         .99*********************************************************

S: 236   llkkllevdpekrlssledi  255

         l+ kl++vdp kr+ s e +

Q: 260   LFFKLFKVDPTKRIQSFESL  279

         **************998775

Domain Sequence
(FASTA)

FEVLRSIGKG SFGKVCIVRR KKTENEVYAM KYMNKLSSWK HGAIDHVLRE LEILSTLRHQ 60

FLVNLWFTFQ DEEDIFMVSD LLMGGDLRYH IQRHVHFTFD DVRIYFCELA LVLDYLRNKH 120

IIHRDIKPDN ILLDERGHLH LTDFNIATVL NDEHPCAKSF AGTKPYYDIT APEIFNSSSG 180

YDYAVDWWSL GVTMYEVLRH KRPFNIGSDT TNEEVTALHN DGSISFPVDW GQPIMNLFFK 240

LFKVDPTKRI QSFESL 256

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013