EKS-CII-00117

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00117

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PKA	469.5	2.0E-141	60	314	255

Status

Unreviewed

Ensembl Protein

ENSCINP00000013406

UniProt Accession

F6PH07;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100176009

Gene Synonyms/Alias

LOC100176009;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000006522	ENSCINP00000013406	ENSCINT00000013406

Organism

Ciona intestinalis

Functional Description

Protein Length

367

Protein Sequence
(FASTA)

MHSLYSLFGK DKEKHHNKQQ WEEYNLNYYA YVKAFLAEAK EEFLKKWENP IQNNSKLDDF 60

ERLKTLGTGS FGRVILVKRK ENSNYYAMKI LDKQKVVKLK QVEHTLNEKK ILQAINFPFL 120

VKMDFSFKDN SNLYMVLEYV IGGEMFSHLR RIGRFSESHS RFYAAQIVLG FEYLHYLDII 180

YRDLKPENLL IDQQGYIQVT DFGFAKRVKG RTWTLCGTPE YLAPEIILSK GYNKAVDWWA 240

LGVLIYEMAA GYPPFFADQP IQIYEKIVSG KVRFPSHFTS ELKDLLRNLL QVDLTKRFGN 300

LKNGVSDIKG HRWFQPIDWI AVYQRKLDAP FIPKFKHPGS TENFDDYEEE QLRVHSTEKC 360

VKEFADF 367

Nucleotide Sequence
(FASTA)

ATGCATAGTT TGTATTCATT GTTTGGTAAG GATAAAGAAA AACATCATAA TAAGCAACAA 60

TGGGAAGAAT ACAATCTCAA TTATTATGCG TATGTGAAAG CCTTCTTGGC AGAAGCAAAG 120

GAAGAATTTT TAAAGAAATG GGAAAATCCT ATTCAGAATA ATTCAAAATT GGACGATTTT 180

GAGCGTCTGA AAACTTTAGG AACTGGATCG TTTGGTCGAG TTATTCTTGT TAAAAGGAAG 240

GAGAATTCAA ATTATTATGC CATGAAAATA CTAGATAAAC AAAAGGTAGT AAAGCTGAAG 300

CAAGTGGAAC ACACTTTAAA CGAGAAGAAA ATCTTACAAG CTATTAATTT TCCTTTCTTA 360

GTTAAAATGG ATTTCTCGTT TAAGGACAAC AGCAATCTAT ACATGGTGCT GGAGTATGTG 420

ATAGGAGGGG AAATGTTTTC ACATTTAAGA AGAATAGGAA GATTCAGTGA ATCTCATTCA 480

CGATTCTACG CGGCACAAAT CGTCCTTGGC TTCGAATACC TTCACTACCT AGACATCATT 540

TACCGAGATC TCAAACCTGA GAATCTGCTT ATTGACCAGC AAGGTTACAT ACAGGTCACT 600

GACTTTGGGT TCGCAAAGCG TGTTAAAGGC CGCACATGGA CACTATGTGG GACCCCTGAA 660

TACTTGGCAC CTGAGATTAT TCTTAGCAAG GGTTACAACA AAGCTGTGGA TTGGTGGGCT 720

CTTGGTGTGC TTATATACGA GATGGCAGCC GGCTATCCTC CTTTCTTCGC TGATCAACCC 780

ATCCAAATAT ACGAGAAGAT TGTTTCAGGG AAGGTTCGAT TCCCGTCACA TTTCACTTCC 840

GAGTTAAAGG ATTTGCTTCG AAATCTACTC CAAGTTGATT TGACGAAAAG ATTTGGGAAC 900

CTTAAGAATG GAGTGTCCGA TATAAAGGGA CACAGATGGT TCCAACCAAT TGATTGGATT 960

GCTGTGTATC AAAGAAAGTT GGATGCTCCC TTCATCCCGA AGTTCAAACA CCCGGGTTCC 1020

ACGGAAAACT TTGATGATTA TGAAGAAGAG CAACTCCGAG TTCACTCCAC GGAAAAGTGC 1080

GTCAAAGAAT TTGCAGACTT TTAA 1104

Domain Profile

S: 1     ferlktlGtGsfGrvelvrekeskkyyalkvlskekvvklkqvehvknekrvlkavefpf  60

         ferlktlGtGsfGrv lv+ ke+ +yya+k+l+k+kvvklkqveh+ nek++l+a++fpf

Q: 60    FERLKTLGTGSFGRVILVKRKENSNYYAMKILDKQKVVKLKQVEHTLNEKKILQAINFPF  119

         799*********************************************************

S: 61    lvkllasfkdesnlylvleyveGGelfsylrkvrrfsekaarfyaaeivlaleylhsldl  120

         lvk+ +sfkd+snly+vleyv GGe+fs+lr+++rfse+++rfyaa+ivl +eylh ld+

Q: 120   LVKMDFSFKDNSNLYMVLEYVIGGEMFSHLRRIGRFSESHSRFYAAQIVLGFEYLHYLDI  179

         ************************************************************

S: 121   iyrdlkpenllldkeGyikvtdfGfakkvkdrtwtlcGtpeylapeiiqskgynkavdww  180

         iyrdlkpenll+d++Gyi+vtdfGfak+vk+rtwtlcGtpeylapeii skgynkavdww

Q: 180   IYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWW  239

         ************************************************************

S: 181   alGvliyellaGyppffddqpikiyekivsgklkfpsklssdlkdllkkllqvdltkrlg  240

         alGvliye++aGyppff+dqpi+iyekivsgk++fps+++s+lkdll++llqvdltkr+g

Q: 240   ALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSELKDLLRNLLQVDLTKRFG  299

         ************************************************************

S: 241   nlkngvedikehkwf  255

         nlkngv+dik h+wf

Q: 300   NLKNGVSDIKGHRWF  314

         **************9

Domain Sequence
(FASTA)

FERLKTLGTG SFGRVILVKR KENSNYYAMK ILDKQKVVKL KQVEHTLNEK KILQAINFPF 60

LVKMDFSFKD NSNLYMVLEY VIGGEMFSHL RRIGRFSESH SRFYAAQIVL GFEYLHYLDI 120

IYRDLKPENL LIDQQGYIQV TDFGFAKRVK GRTWTLCGTP EYLAPEIILS KGYNKAVDWW 180

ALGVLIYEMA AGYPPFFADQ PIQIYEKIVS GKVRFPSHFT SELKDLLRNL LQVDLTKRFG 240

NLKNGVSDIK GHRWF 255

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013