EKS-CII-00270

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00270

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TBCK	170.4	3.5E-50	18	272	255

Status

Unreviewed

Ensembl Protein

ENSCINP00000013944

UniProt Accession

F6VDB6;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100177070

Gene Synonyms/Alias

LOC100177070;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000006797	ENSCINP00000013944	ENSCINT00000013944

Organism

Ciona intestinalis

Functional Description

Protein Length

861

Protein Sequence
(FASTA)

LFPLMKCSLG CMSFVTAALP HNQCGINGLP LTPNSITSLG LAQQLKTLKH ENLCSYVDFR 60

CGRHERIFAV SELYVDSVFN KITQPTELKQ DDWRKYSLNI VHGVLNGLNY LNSKGYIQLN 120

LEPKNILLNE NGTPKLSGYG LHHMTDGGKL LSGPLGSLKY SSPEQILSCC YSEIPMATSS 180

KSDVWSACIV LLELLHRELL WDSVENKSLV KRVLCLSANK SSHKNIEVLC QNFKENLSLN 240

ETDDVTKLIK VILENGLNVE SSQRATPLQI LNKLGKDLNL TNEQQPADTN GKFEKTVPSE 300

NTNPLMEMDS EEIWCLWNLA GGDMVAEVLR SVTTTPPIRT VPLFVTVHGD LYGLEPSPEN 360

LFNPGYKLLS LDTVESRLEV NTENISLIYP LLELKSPDVS HESAKLPLLI RENDFDYQVH 420

RIALYRRLLL GYPYLRDKLL KEARIDIPPY CRGRVWAGLL DVKGDLEEQY INIDKDTPIV 480

TDRQIAVDVP RCHQYDSMLC SPTAHEKLKR VLKAWLMSHP HLTYWQGLDS LCAVFVHLNF 540

NDEPRAWASM SQFIDKYLHD FFLKDNSAII QEYLVVFSHL LTFHDPLLSC HMQEIGFIPD 600

LYAIPWFLTM FAHVFPLHKI FHLWDTLLLG NSSFPLCIGV AILQQLRGQL LQSDFNECIL 660

LFSDLPEIDI DGVVKKSIQV FCQSPKSSTF RVHAQKEEKC KRQTVSYYTE DYNTLPKTEL 720

SETAIPLSEL KQEVCCRISA DDLIQLCELK GSNNSKTPAK ATKSGKPRIF IIDIRSSDEF 780

SRGCVPGSFN FPLAPNKSIP QLVQMISKQS PKVVVVIGNK STREDREFCF ELLKEGLKGV 840

CVLHGGIDIL KPVGVLTVPS Q 861

Nucleotide Sequence
(FASTA)

CTTTTTCCCC TTATGAAATG CAGTTTAGGA TGTATGTCAT TTGTGACTGC TGCTCTGCCA 60

CATAACCAGT GTGGTATTAA TGGACTTCCC TTGACTCCTA ACTCCATCAC ATCTCTTGGA 120

CTTGCACAGC AGTTAAAGAC ACTGAAGCAT GAAAATCTTT GCAGTTACGT TGATTTTCGA 180

TGTGGTAGGC ATGAGAGAAT TTTTGCCGTT TCTGAGCTAT ATGTGGATAG TGTGTTCAAC 240

AAAATCACAC AACCAACAGA ATTAAAACAA GATGATTGGA GGAAGTACAG CTTAAACATT 300

GTCCATGGAG TACTTAATGG ACTCAATTAT TTAAACTCAA AAGGATATAT TCAACTAAAC 360

TTAGAGCCCA AAAATATTCT GTTAAATGAG AATGGCACAC CCAAGCTGTC TGGATATGGT 420

TTACACCATA TGACAGATGG AGGGAAATTA CTTAGTGGAC CATTAGGTAG CTTAAAATAT 480

TCCTCTCCAG AACAAATACT GTCATGCTGC TACTCAGAGA TACCTATGGC CACCAGCAGC 540

AAATCTGATG TATGGTCTGC TTGTATAGTA CTGTTGGAAC TACTGCATAG GGAGTTGCTG 600

TGGGACAGTG TGGAAAATAA AAGTCTTGTC AAACGTGTGC TTTGTCTTTC TGCAAACAAA 660

AGCTCACACA AAAACATTGA GGTTTTGTGC CAAAATTTTA AAGAAAATCT AAGTCTAAAT 720

GAAACCGATG ACGTAACAAA GTTAATAAAA GTGATCTTGG AAAATGGATT GAATGTTGAA 780

TCCTCACAAA GAGCAACGCC ATTGCAGATT CTTAACAAAC TTGGTAAAGA TCTGAATTTA 840

ACCAATGAGC AACAACCTGC AGACACCAAT GGTAAGTTTG AAAAAACTGT ACCTAGTGAA 900

AACACCAACC CTTTAATGGA AATGGACAGT GAAGAGATAT GGTGTCTATG GAACTTGGCT 960

GGGGGAGATA TGGTTGCTGA AGTTTTACGT TCTGTGACCA CCACCCCTCC AATTCGTACA 1020

GTTCCATTAT TTGTAACTGT TCATGGCGAC CTTTACGGTC TTGAGCCATC CCCAGAAAAT 1080

TTGTTTAACC CTGGCTATAA ATTACTTTCT CTTGACACTG TTGAAAGCAG GCTTGAGGTT 1140

AACACTGAAA ATATCTCTCT CATATACCCA CTACTCGAGC TCAAATCACC AGATGTTTCA 1200

CATGAATCTG CCAAGTTACC TTTGCTAATA CGTGAAAATG ATTTTGATTA CCAAGTGCAT 1260

CGTATTGCTC TGTACAGGCG ATTACTCCTG GGCTACCCTT ACTTACGAGA CAAGTTATTA 1320

AAGGAAGCAC GAATTGACAT TCCACCATAT TGTAGGGGTA GGGTATGGGC AGGGCTTTTA 1380

GATGTCAAAG GTGACTTGGA AGAGCAATAT ATCAACATTG ATAAAGATAC TCCAATAGTG 1440

ACAGACAGAC AAATTGCTGT TGATGTACCA CGCTGCCACC AATATGATTC AATGCTGTGT 1500

TCACCTACCG CTCACGAAAA GTTAAAGCGG GTTCTTAAAG CGTGGTTGAT GTCACATCCA 1560

CATCTCACAT ACTGGCAAGG ACTAGATTCA CTTTGTGCTG TATTTGTTCA TTTAAATTTC 1620

AATGATGAAC CAAGAGCATG GGCCTCCATG TCCCAATTCA TTGACAAGTA CCTTCATGAC 1680

TTCTTTCTCA AAGATAACTC CGCCATCATT CAAGAATATC TTGTTGTATT CTCCCACTTG 1740

TTAACCTTCC ATGACCCTTT GCTTTCATGT CATATGCAGG AGATTGGTTT TATACCAGAC 1800

CTTTATGCAA TTCCTTGGTT TTTAACCATG TTTGCTCATG TATTTCCTCT GCATAAGATA 1860

TTCCATCTAT GGGACACCTT GCTGCTTGGA AATTCTTCTT TTCCTCTCTG TATCGGGGTG 1920

GCCATCTTAC AACAATTACG TGGACAGTTA CTTCAGAGTG ATTTTAACGA ATGCATCCTT 1980

CTATTTTCTG ACCTGCCTGA AATAGACATT GATGGTGTGG TGAAAAAATC CATACAAGTT 2040

TTCTGTCAGT CTCCAAAAAG CTCCACATTT CGTGTTCATG CACAGAAAGA AGAAAAATGC 2100

AAACGTCAAA CAGTATCTTA CTACACAGAA GACTATAATA CTCTTCCAAA AACTGAACTC 2160

TCAGAAACTG CGATTCCACT CTCAGAACTT AAACAAGAAG TTTGCTGCAG AATTTCGGCA 2220

GATGATTTAA TTCAGCTTTG TGAACTAAAA GGATCCAATA ACTCTAAGAC TCCAGCTAAA 2280

GCAACCAAAT CTGGCAAGCC TAGGATCTTC ATCATTGACA TTCGATCTTC AGATGAGTTT 2340

TCGCGTGGCT GTGTACCTGG AAGCTTTAAC TTCCCCCTGG CACCCAACAA ATCAATCCCC 2400

CAGTTGGTCC AAATGATTTC TAAACAGAGC CCAAAAGTAG TTGTAGTTAT TGGCAACAAA 2460

TCAACACGCG AGGACCGAGA ATTTTGCTTC GAACTCCTCA AAGAAGGATT AAAAGGCGTA 2520

TGTGTCTTGC ATGGTGGAAT TGATATTTTA AAACCTGTCG GTGTTCTTAC AGTGCCATCA 2580

CAATAA 2586

Domain Profile

S: 1     llaqdkdGsnGlplasnakkilGrfqiLkelqhdrLcqYldisrgkhervivvaehlels  60

         +l+++++G nGlpl++n++  lG +q+Lk+l+h++Lc Y+d+  g+her+  v+e +  s

Q: 18    ALPHNQCGINGLPLTPNSITSLGLAQQLKTLKHENLCSYVDFRCGRHERIFAVSELYVDS  77

         589****************************************************77766

S: 61    L.eDllkerkpvse...slvlriayevlsgldylnkhnivhralepksilldrkgqkvkL  116

         + + + +  ++++       l+i++ vl+gl+yln ++ ++ +lepk+ill+ +g   kL

Q: 78    VfNKITQPTELKQDdwrKYSLNIVHGVLNGLNYLNSKGYIQLNLEPKNILLNENGT-PKL  136

         516677767776642225689**********************************9.9**

S: 117   akyGLyhltayGkdvdfpigygsylaPerilqd..edkllaatvksDvWsLglillelil  174

         ++yGL+h+t++Gk  + p+g  +y +Pe+il    ++ ++a++ ksDvWs  ++llel+

Q: 137   SGYGLHHMTDGGKLLSGPLGSLKYSSPEQILSCcySEIPMATSSKSDVWSACIVLLELLH  196

         *******************************988899***********************

S: 175   gikLfaeldlserlkillklst...vdetliklae...ekkcldiikklderleallkkC  228

            L+ +++    +k +l ls+   +++++++l +   e+  l+   ++ + ++ +l++

Q: 197   RELLWDSVENKSLVKRVLCLSAnksSHKNIEVLCQnfkENLSLNETDDVTKLIKVILENG  256

         ***************9988875222556777776511155677888888889999*****

S: 229   LtllpskRpspdellk  244

         L++ +s+R++p ++l+

Q: 257   LNVESSQRATPLQILN  272

         ***********99986

Domain Sequence
(FASTA)

ALPHNQCGIN GLPLTPNSIT SLGLAQQLKT LKHENLCSYV DFRCGRHERI FAVSELYVDS 60

VFNKITQPTE LKQDDWRKYS LNIVHGVLNG LNYLNSKGYI QLNLEPKNIL LNENGTPKLS 120

GYGLHHMTDG GKLLSGPLGS LKYSSPEQIL SCCYSEIPMA TSSKSDVWSA CIVLLELLHR 180

ELLWDSVENK SLVKRVLCLS ANKSSHKNIE VLCQNFKENL SLNETDDVTK LIKVILENGL 240

NVESSQRATP LQILN 255

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005622	; C:intracellular
GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0005097	; F:Rab GTPase activator activity
GO:0032851	; P:positive regulation of Rab GTPase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR000195	; Rab-GTPase-TBC_dom.
IPR001763	; Rhodanese-like_dom.

Pfam

PF00069	; Pkinase; 1.
PF00566	; RabGAP-TBC; 1.
PF00581	; Rhodanese; 1.

SMARTs

SM00450	; RHOD; 1.
SM00164	; TBC; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS50206	; RHODANESE_3; 1.
PS50086	; TBC_RABGAP; 1.

Prints

Created Date

20-Feb-2013