EKS-CII-00157

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00157

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PLK	327.4	5.6E-98	125	380	256

Status

Unreviewed

Ensembl Protein

ENSCINP00000015359

UniProt Accession

F6XWE7;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100183083

Gene Synonyms/Alias

LOC100183083;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000007490	ENSCINP00000015359	ENSCINT00000015359

Organism

Ciona intestinalis

Functional Description

Protein Length

754

Protein Sequence
(FASTA)

MPTTANTSSS AYSSAPSSCC DTNERNRRKS EVVPGQVLHI GNQPCFLDNP QSYSSSNNES 60

PVYHELLHPS YSAPTLLHNK INLKPQLPQS CQQRRRSHQH VPLTTSKHEV DDHLYLHDAI 120

NGKVYQKRRM LGKGGFARVY EVIEECDIED SGMIFAAKVI DKSRLSRPQQ REKVDIEVKL 180

LKAARGHPNV VAFHKSFEDE KFICILLELC NKKSLAQYLR RKQYLSEAEV CCIARQIVSG 240

LSHLHDNGII HRDLKLGNIL LTDDMTVKIG DFGLATLVEW GKKKTICGTP NFIAPEVLQR 300

QGHGPEADVW ALGCLLYTLL VGKPPFETSC LRETYRCILK NSYRIPSTVS TEAADLLRWM 360

LRHKPKMRPT LSQVSSHAFF TKHSETSSIS TPISKTYTLS FHGNGLGHVS NSSTECKSCT 420

IVGSKTNEGS IPSKEDTKQN EASPACVDVP TTKSPVKLIA CKLQRHFRVP SPRKYVRAAA 480

STLFDKKTEG KQPESSKTNF IFSFYLYIHI SNVFNLSDNK PIRKSSATVN VACQNQPGAA 540

AASTWVCKWV DYSNRYGFGY QLANGRVCVL FNDGKHISML PGGKVIEYAS NEQSNAIRFS 600

VDSVPPCLER YANMLNNFTH YMDTKLRHNT DVRQQQQTSN ARMLTWFRTD DYVLMYLNDG 660

TLQVNYCTDH VKMNITSIHR RSAMKITVVD ENRQTSTYTT TTFNDQAPTS IKSRLPLLHD 720

HFHNLFPDVE CSSHPFCAVS SQTHPNLNVD KLST 754

Nucleotide Sequence
(FASTA)

ATGCCAACCA CAGCAAATAC GTCATCATCT GCATATTCAT CCGCACCATC ATCGTGCTGT 60

GACACTAACG AGCGAAATCG AAGAAAATCT GAAGTTGTTC CCGGTCAAGT ACTTCATATC 120

GGAAACCAGC CTTGCTTTTT AGACAATCCC CAGAGCTATT CTTCTAGCAA TAACGAAAGT 180

CCGGTTTATC ACGAGTTGCT GCACCCCTCA TATTCCGCAC CAACTTTATT ACACAACAAA 240

ATCAACTTGA AACCACAACT ACCTCAGTCG TGTCAACAAC GACGTCGTTC CCACCAACAC 300

GTACCCCTCA CAACCAGCAA ACACGAAGTA GATGACCATC TATATCTCCA TGATGCAATT 360

AATGGAAAGG TTTATCAGAA GAGACGTATG CTTGGAAAGG GAGGCTTCGC TCGAGTTTAC 420

GAAGTCATCG AAGAATGCGA CATTGAGGAT TCTGGAATGA TTTTTGCTGC GAAAGTCATC 480

GATAAATCGC GGCTGTCGCG ACCGCAACAG CGCGAAAAGG TCGACATTGA AGTAAAATTA 540

TTAAAAGCGG CACGTGGTCA CCCTAATGTG GTCGCCTTTC ACAAAAGCTT TGAAGACGAA 600

AAATTTATCT GTATTTTGTT GGAACTTTGC AATAAAAAGA GCCTCGCGCA ATATCTAAGG 660

AGAAAGCAAT ATCTGAGTGA AGCGGAGGTT TGCTGCATCG CAAGACAAAT CGTATCCGGG 720

CTTTCACATC TTCACGATAA TGGGATAATC CACAGAGACT TAAAGTTGGG AAATATACTC 780

CTCACAGATG ACATGACGGT CAAGATTGGA GACTTTGGTC TTGCAACACT TGTAGAATGG 840

GGAAAGAAAA AAACAATATG CGGAACGCCG AACTTTATCG CGCCAGAGGT TCTTCAAAGA 900

CAGGGTCACG GTCCAGAGGC CGATGTTTGG GCGCTAGGTT GTTTACTCTA TACTTTGTTG 960

GTTGGCAAGC CACCCTTTGA AACTTCTTGC TTAAGGGAGA CTTACCGATG TATCTTAAAG 1020

AATAGTTACC GCATACCTTC CACTGTGTCG ACAGAAGCGG CAGATTTGTT ACGTTGGATG 1080

TTACGTCATA AACCAAAAAT GCGACCCACG CTTAGCCAAG TATCGTCCCA TGCGTTCTTT 1140

ACAAAGCATT CTGAGACATC CAGTATCTCC ACACCCATCT CGAAAACTTA CACACTAAGT 1200

TTCCACGGCA ACGGTTTAGG CCACGTATCT AATAGTTCCA CGGAATGCAA ATCGTGCACG 1260

ATCGTCGGTT CGAAGACCAA CGAAGGTTCG ATCCCGAGTA AAGAAGACAC GAAACAAAAC 1320

GAAGCTTCGC CTGCCTGTGT TGACGTCCCG ACCACCAAGA GTCCAGTAAA ACTTATAGCA 1380

TGCAAACTAC AACGCCATTT TCGTGTTCCA TCTCCCCGGA AATATGTTCG AGCAGCAGCT 1440

TCCACCTTGT TTGACAAGAA AACCGAAGGA AAACAACCCG AATCGAGTAA GACAAATTTT 1500

ATTTTTAGTT TTTATTTGTA TATTCATATT TCAAACGTTT TTAATTTATC AGACAACAAA 1560

CCGATTAGAA AGTCGTCAGC CACTGTAAAC GTGGCTTGCC AAAATCAGCC CGGAGCAGCT 1620

GCAGCTTCAA CGTGGGTTTG TAAGTGGGTG GATTACTCAA ACCGCTACGG TTTCGGATAC 1680

CAACTCGCCA ATGGTCGCGT GTGTGTTCTA TTCAACGACG GAAAACACAT CTCGATGCTT 1740

CCCGGTGGAA AAGTAATCGA ATACGCGTCG AACGAACAAT CCAATGCTAT CCGGTTTTCC 1800

GTGGATTCCG TCCCACCATG TTTGGAAAGA TACGCGAACA TGTTGAACAA CTTTACGCAT 1860

TACATGGACA CTAAACTACG TCATAACACC GATGTACGTC AGCAACAACA GACGAGTAAC 1920

GCTCGTATGT TAACTTGGTT CCGCACCGAT GATTATGTGT TAATGTACCT GAATGATGGG 1980

ACGCTCCAAG TCAACTATTG TACGGACCAT GTTAAAATGA ACATAACGTC AATCCACAGA 2040

AGATCTGCCA TGAAAATAAC TGTCGTAGAC GAGAACCGCC AAACATCCAC CTACACGACG 2100

ACAACTTTCA ACGATCAAGC TCCAACGTCA ATTAAATCCC GGCTCCCCCT TCTTCACGAT 2160

CACTTCCATA ACCTTTTTCC GGATGTTGAA TGTTCCTCGC ATCCATTCTG TGCAGTTTCA 2220

TCACAAACTC ACCCCAATCT AAATGTTGAC AAACTATCCA CGTAA 2265

Domain Profile

S: 1     yergkllGkGgfakcyelkd....letkevfavkvvpksllakekqrekvekeieihrsl  56

         y++ ++lGkGgfa++ye+ +     +++ +fa+kv++ks+l +++qrekv+ e+++ +

Q: 125   YQKRRMLGKGGFARVYEVIEecdiEDSGMIFAAKVIDKSRLSRPQQREKVDIEVKLLKAA  184

         89**************98652222468899*************************97765

S: 57    .khknivklyeffedkenvylvlelcsrrslaellkrrkaltepevryylrqivsglkyl  115

           h+n+v++++ fed++++ ++lelc+++sla++l+r++ l+e ev  + rqivsgl +l

Q: 185   rGHPNVVAFHKSFEDEKFICILLELCNKKSLAQYLRRKQYLSEAEVCCIARQIVSGLSHL  244

         16**********************************************************

S: 116   hekrilhrdlklgnlflneelevkigdfGlatrlekeeerkktlcGtPnyiaPevlskkg  175

         h++ i+hrdlklgn++l+++++vkigdfGlat +e    +kkt+cGtPn+iaPevl+++g

Q: 245   HDNGIIHRDLKLGNILLTDDMTVKIGDFGLATLVE--WGKKKTICGTPNFIAPEVLQRQG  302

         **********************************9..67899******************

S: 176   hslevdiWslGcilytllvGkPPfetkelketyekikkaeyslPsslskeaksliakllk  235

         h+ e+d+W+lGc+lytllvGkPPfet++l+ety++i k++y++Ps++s+ea++l++ +l+

Q: 303   HGPEADVWALGCLLYTLLVGKPPFETSCLRETYRCILKNSYRIPSTVSTEAADLLRWMLR  362

         ************************************************************

S: 236   kePeerpsleevlkdefl  253

         ++P+ rp+l++v ++ f+

Q: 363   HKPKMRPTLSQVSSHAFF  380

         ***************998

Domain Sequence
(FASTA)

YQKRRMLGKG GFARVYEVIE ECDIEDSGMI FAAKVIDKSR LSRPQQREKV DIEVKLLKAA 60

RGHPNVVAFH KSFEDEKFIC ILLELCNKKS LAQYLRRKQY LSEAEVCCIA RQIVSGLSHL 120

HDNGIIHRDL KLGNILLTDD MTVKIGDFGL ATLVEWGKKK TICGTPNFIA PEVLQRQGHG 180

PEADVWALGC LLYTLLVGKP PFETSCLRET YRCILKNSYR IPSTVSTEAA DLLRWMLRHK 240

PKMRPTLSQV SSHAFF 256

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000959	; POLO_box_duplicated_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00659	; POLO_box; 2.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50078	; POLO_BOX; 2.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013