EKS-CII-00159

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00159

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/DYRK	462.8	5.2E-139	71	384	314

Status

Unreviewed

Ensembl Protein

ENSCINP00000015725

UniProt Accession

F6T718;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100176767

Gene Synonyms/Alias

LOC100176767;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000007679	ENSCINP00000015725	ENSCINT00000015725

Organism

Ciona intestinalis

Functional Description

Protein Length

440

Protein Sequence
(FASTA)

SYISPDEAMK QFMQKLTSYE HHEVFSYPRI YFTGTSAKKR PGVVGASNNC GYDDDQCSYI 60

AVPHDHIAYR YEILKVIGKG SFGQVMKAFD HKLHQHVALK IVRNEKRFHR QAAEEIRILE 120

HLRKQDKDNA MNIIHMMESF TFRNHICMTF ELLSINLYEL IKKNKFQGFS LQLVRKFAHS 180

ILQCLEALSR NRIIHCDLKP ENILLKQQGR SGIKVIDFGS SCYEHQRVYT YIQSRFYRAP 240

EVILGGRYGM PIDMWSFGCI LAELLTGYPL LPGEDEADQL ACSIELLGMP PRRLLDQSKR 300

AKNFISSKGH PRYCQVTTLS DGSTVLGPGR SRRGKLRGPP GQREWVTALK GCDDPLFTDF 360

LRRCLDWDPA ARMTPSQALR HSWLRRRLPK PPGGATAHRG DNSTIKNHSS FNRQPSGNKA 420

KDMSVTVAAT TRTVLPKIVG 440

Nucleotide Sequence
(FASTA)

AGCTACATTT CGCCTGACGA AGCAATGAAG CAGTTTATGC AAAAGTTAAC TTCATACGAG 60

CACCATGAAG TGTTCAGCTA CCCGCGTATT TACTTCACCG GTACCTCAGC AAAGAAACGG 120

CCTGGCGTTG TTGGTGCAAG CAACAACTGT GGATACGATG ACGACCAATG CTCTTACATA 180

GCTGTACCAC ATGACCACAT CGCATATCGC TACGAAATCC TGAAAGTTAT TGGCAAAGGA 240

AGTTTTGGGC AGGTCATGAA AGCGTTTGAT CATAAACTAC ACCAACATGT CGCTTTGAAA 300

ATCGTGAGGA ACGAGAAACG TTTCCACCGG CAAGCCGCTG AAGAAATACG AATATTAGAA 360

CATCTTAGGA AACAAGATAA AGACAATGCA ATGAACATAA TTCATATGAT GGAGAGTTTT 420

ACGTTCCGAA ACCACATCTG TATGACGTTT GAACTACTTA GTATCAACCT CTATGAGCTC 480

ATAAAGAAGA ATAAATTCCA AGGCTTTTCC CTTCAGCTGG TGAGAAAATT CGCCCACTCG 540

ATTCTACAAT GTTTGGAAGC CTTATCGCGC AACCGCATTA TTCACTGCGA CTTAAAACCT 600

GAGAATATCC TACTTAAACA GCAAGGCAGA AGCGGGATTA AGGTCATAGA CTTCGGCTCA 660

TCCTGCTACG AGCACCAGCG TGTCTACACT TATATCCAAT CCCGGTTCTA TCGCGCTCCT 720

GAGGTTATCT TAGGCGGCAG ATACGGCATG CCGATCGATA TGTGGAGTTT CGGGTGCATT 780

CTGGCCGAAC TTCTTACCGG TTATCCCCTC CTGCCAGGCG AGGATGAAGC GGACCAACTA 840

GCTTGCTCTA TAGAGCTACT AGGCATGCCG CCAAGGCGTC TTCTTGACCA ATCAAAACGG 900

GCTAAGAATT TCATTAGTTC AAAAGGCCAC CCTCGTTATT GTCAAGTGAC AACTTTATCG 960

GATGGGAGCA CCGTCCTTGG TCCCGGCCGC TCCCGTAGAG GAAAGCTTAG AGGGCCTCCT 1020

GGTCAGCGAG AATGGGTTAC AGCGCTCAAA GGCTGCGACG ACCCTCTCTT CACCGATTTC 1080

CTGCGTAGAT GTCTAGACTG GGACCCGGCA GCGCGCATGA CGCCTTCCCA AGCCCTACGT 1140

CACTCCTGGC TTCGTCGGCG CCTCCCCAAA CCGCCTGGTG GCGCTACAGC GCACCGAGGT 1200

GACAACTCGA CCATTAAAAA CCATTCATCG TTTAACCGTC AACCATCAGG AAACAAAGCC 1260

AAGGACATGT CAGTCACCGT CGCCGCAACC ACGCGTACTG TGCTACCCAA GATCGTAGGA 1320

TAG 1323

Domain Profile

S: 1     yevlevigkGsfgqVvkaldkktkeivaikiiknkkrfarqaqeEveiLeklnkkdkeek  60

         ye+l+vigkGsfgqV+ka d+k +++va+ki++n+krf+rqa+eE++iLe+l+k+dk+++

Q: 71    YEILKVIGKGSFGQVMKAFDHKLHQHVALKIVRNEKRFHRQAAEEIRILEHLRKQDKDNA  130

         9***********************************************************

S: 61    ynvvrllelfvfrnhlclvfellsqnLyellkknkfsglslklvrklaqqilkaLklLke  120

         +n+++++e+f+frnh+c++fells+nLyel+kknkf+g+sl+lvrk+a++il++L++L++

Q: 131   MNIIHMMESFTFRNHICMTFELLSINLYELIKKNKFQGFSLQLVRKFAHSILQCLEALSR  190

         ************************************************************

S: 121   lkiiHaDlKPeNillvekkrsevkviDFGsssavsqkeiytyiqsrfYraPEiilglkyd  180

         ++iiH+DlKPeNill++++rs +kviDFGss++++q+ +ytyiqsrfYraPE+ilg +y

Q: 191   NRIIHCDLKPENILLKQQGRSGIKVIDFGSSCYEHQR-VYTYIQSRFYRAPEVILGGRYG  249

         *************************************.**********************

S: 181   eaiDmWSlGcvlaElftGkpLfpGenevdqlalivevlglppekllekakkakkfftkke  240

         + iDmWS+Gc+laEl+tG+pL+pGe+e dqla+ +e+lg+pp++ll+++k+ak+f+++k+

Q: 250   MPIDMWSFGCILAELLTGYPLLPGEDEADQLACSIELLGMPPRRLLDQSKRAKNFISSKG  309

         ************************************************************

S: 241   apkyilktkksdrkkklvlnvkkaakkrkaplskelgealkekedklfkdllkrmleldp  300

         +p+y+ +t+ sd +++l  ++++++k r +p+++e+++alk ++d lf+d+l+r+l++dp

Q: 310   HPRYCQVTTLSDGSTVLGPGRSRRGKLRGPPGQREWVTALKGCDDPLFTDFLRRCLDWDP  369

         ************************************************************

S: 301   akRitpkealkhpfv  315

         a+R+tp++al+h+++

Q: 370   AARMTPSQALRHSWL  384

         *************96

Domain Sequence
(FASTA)

YEILKVIGKG SFGQVMKAFD HKLHQHVALK IVRNEKRFHR QAAEEIRILE HLRKQDKDNA 60

MNIIHMMESF TFRNHICMTF ELLSINLYEL IKKNKFQGFS LQLVRKFAHS ILQCLEALSR 120

NRIIHCDLKP ENILLKQQGR SGIKVIDFGS SCYEHQRVYT YIQSRFYRAP EVILGGRYGM 180

PIDMWSFGCI LAELLTGYPL LPGEDEADQL ACSIELLGMP PRRLLDQSKR AKNFISSKGH 240

PRYCQVTTLS DGSTVLGPGR SRRGKLRGPP GQREWVTALK GCDDPLFTDF LRRCLDWDPA 300

ARMTPSQALR HSWL 314

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013