EKS-CII-00123

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00123

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Ryk	339.3	1.3E-101	313	582	270

Status

Unreviewed

Ensembl Protein

ENSCINP00000018455

UniProt Accession

F6QDT9;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100177957

Gene Synonyms/Alias

LOC100177957;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000009096	ENSCINP00000018455	ENSCINT00000018455

Organism

Ciona intestinalis

Functional Description

Protein Length

593

Protein Sequence
(FASTA)

MRVCAYILAV VLLPCMSKCS IDLYLAEDQV EKLFGIADAE MYYIRNGIIN ENAVNFVAHV 60

QPEHTDLTYL WKVTNKAITV AYDLDILDVQ KSPAQLNTGS VEMNKHSILY PPKLESKSGT 120

IRYSEDLQPQ TLKVSLVCTG EREGNVTVTM KLKLVMDSGT DLVVNIKRLK KCLKTHSFVE 180

DKPVLTDQPS EPNDQDLNLG GTQQSTSAFY ISVSVVSSFI VLIVVGVTLW HVRMSKRYQR 240

SGVDNCIPMQ PGAQHLNQFL RPDLPNNALK PPSHSSLMQI ITPLINDLGT DINEIQSKLS 300

AIAIPRENVD IGELTLKGTF ARIYKGTLDD GTPVLIKTVS DMATEEQKRL LLFESSLLRG 360

MHHRNLLSMK HVVLQDDSTP PMVLFHFMEG GNLKHYLQGL KLKESPGLVS GIFGSGSTKY 420

EQVSTQDLVE MAIQIACGMT YLSKRGLVHK DLAARNCVID RDLKVKISDN ALSRDAFPAD 480

YCCLGDNENR PVRWLGLESL VHKVYSSASD VWSFGVLLWE LQSLAATPYA DIDDFEMASY 540

LKDGFRLSQP INCPDHLYSI IASCWHYSPD QRPSFTKLLQ MLTEFYAELE VYV 593

Nucleotide Sequence
(FASTA)

ATGCGGGTAT GTGCTTATAT TTTGGCTGTG GTTTTACTAC CATGCATGTC CAAATGCAGT 60

ATTGACCTTT ATTTGGCCGA AGATCAAGTG GAAAAGTTAT TTGGCATAGC TGATGCTGAG 120

ATGTACTACA TAAGGAACGG GATTATAAAC GAAAATGCAG TGAATTTTGT TGCCCATGTT 180

CAACCTGAAC ATACAGATCT TACATATTTG TGGAAAGTTA CAAATAAAGC TATTACTGTT 240

GCTTACGATT TGGACATTCT CGATGTACAG AAAAGCCCTG CACAATTAAA TACTGGCAGT 300

GTGGAGATGA ACAAGCATTC CATATTATAT CCACCAAAGC TGGAGTCAAA AAGTGGGACC 360

ATTAGGTACA GTGAGGACTT ACAGCCTCAA ACCCTGAAAG TCAGTCTGGT TTGCACTGGT 420

GAAAGGGAAG GGAATGTTAC AGTGACAATG AAACTTAAGT TAGTGATGGA TTCTGGCACT 480

GATTTAGTAG TCAACATCAA ACGACTGAAG AAATGTTTAA AAACTCATAG CTTTGTAGAA 540

GACAAGCCTG TACTTACTGA TCAACCAAGT GAACCAAATG ATCAGGATTT AAACTTGGGA 600

GGTACACAAC AAAGCACGTC CGCTTTTTAC ATCTCTGTGT CTGTTGTTTC ATCATTTATT 660

GTGTTGATTG TGGTTGGTGT TACATTGTGG CATGTTCGTA TGAGCAAACG ATACCAACGT 720

TCAGGAGTGG ACAACTGTAT ACCAATGCAA CCTGGTGCCC AACATTTGAA CCAGTTCCTG 780

CGCCCAGATC TTCCCAACAA TGCACTAAAA CCGCCTTCCC ATTCAAGCTT AATGCAGATA 840

ATCACTCCGC TAATAAATGA TCTTGGAACT GATATTAATG AAATTCAAAG CAAGTTATCA 900

GCCATTGCCA TTCCCAGGGA AAATGTTGAT ATTGGTGAGC TTACATTGAA AGGAACGTTT 960

GCAAGGATAT ATAAAGGAAC ATTAGATGAT GGAACACCAG TCCTTATCAA GACTGTATCA 1020

GACATGGCAA CTGAAGAACA AAAGCGATTG TTGTTATTTG AAAGCTCGCT GCTACGTGGC 1080

ATGCACCATA GAAATCTACT ATCAATGAAA CATGTTGTTC TTCAAGATGA TTCCACCCCA 1140

CCAATGGTCT TATTCCATTT TATGGAAGGT GGAAATCTAA AGCATTACCT GCAAGGATTA 1200

AAATTGAAGG AATCACCAGG ACTTGTGTCT GGAATATTTG GTTCAGGGTC AACAAAATAT 1260

GAACAAGTTT CGACGCAAGA TCTTGTAGAG ATGGCTATAC AGATTGCTTG TGGTATGACT 1320

TATTTATCAA AAAGAGGATT AGTGCACAAA GATTTGGCTG CAAGAAATTG TGTAATCGAC 1380

AGAGATCTAA AAGTAAAAAT TTCTGACAAC GCATTATCAC GGGATGCTTT CCCTGCCGAT 1440

TATTGTTGCC TTGGCGATAA TGAAAACCGA CCAGTAAGAT GGCTAGGTCT TGAAAGTTTG 1500

GTTCACAAAG TATATTCCTC TGCAAGTGAC GTGTGGTCCT TTGGAGTTTT ATTATGGGAG 1560

TTACAGTCCC TAGCTGCTAC ACCATATGCA GATATTGATG ATTTTGAAAT GGCTAGCTAT 1620

TTGAAAGATG GTTTTCGTCT AAGTCAACCA ATCAACTGCC CAGATCATTT GTACAGCATA 1680

ATTGCAAGTT GTTGGCATTA CTCACCAGAC CAAAGACCCT CCTTTACCAA ACTCCTACAA 1740

ATGCTTACTG AGTTTTATGC AGAACTAGAA GTCTATGTGT AA 1782

Domain Profile

S: 5     ellqeGtfGriyrGkledekdtnkekavlvktvkdqaseiqvalllqealllygvshrni  64

         el   Gtf riy+G+l+d +       vl+ktv d a+e q  lll e++ll+g++hrn+

Q: 313   ELTLKGTFARIYKGTLDDGTP------VLIKTVSDMATEEQKRLLLFESSLLRGMHHRNL  366

         78889*************999......*********************************

S: 65    lsvllvsieea.ekPlvvypalnkgnlkkflricklkdk............ekaqalstk  111

         ls+ +v +++  + P+v+++ ++ gnlk++l+  klk++            +k + +st+

Q: 367   LSMKHVVLQDDsTPPMVLFHFMEGGNLKHYLQGLKLKESpglvsgifgsgsTKYEQVSTQ  426

         *****9997651569****************9999887433333333322256789****

S: 112   qlvelaiqiasalaylhkrevvhkdiaarncviddelqvkltdsalsrdlfPadydclGd  171

         +lve+aiqia+++ yl kr++vhkd+aarncvid +l+vk++d+alsrd fPady clGd

Q: 427   DLVEMAIQIACGMTYLSKRGLVHKDLAARNCVIDRDLKVKISDNALSRDAFPADYCCLGD  486

         ************************************************************

S: 172   nenrPlkWlslealqkeeyssasdvWalGvllWelvtlgksPyaeidpfeleaylkdGyr  231

         nenrP++Wl le+l++++yssasdvW++GvllWel +l+ +Pya+id fe+++ylkdG+r

Q: 487   NENRPVRWLGLESLVHKVYSSASDVWSFGVLLWELQSLAATPYADIDDFEMASYLKDGFR  546

         ************************************************************

S: 232   laqPvncPdelftvmaccWallpeerPsfeqlvscl  267

         l qP+ncPd+l++++a cW+ +p++rPsf +l+++l

Q: 547   LSQPINCPDHLYSIIASCWHYSPDQRPSFTKLLQML  582

         ********************************9876

Domain Sequence
(FASTA)

ELTLKGTFAR IYKGTLDDGT PVLIKTVSDM ATEEQKRLLL FESSLLRGMH HRNLLSMKHV 60

VLQDDSTPPM VLFHFMEGGN LKHYLQGLKL KESPGLVSGI FGSGSTKYEQ VSTQDLVEMA 120

IQIACGMTYL SKRGLVHKDL AARNCVIDRD LKVKISDNAL SRDAFPADYC CLGDNENRPV 180

RWLGLESLVH KVYSSASDVW SFGVLLWELQ SLAATPYADI DDFEMASYLK DGFRLSQPIN 240

CPDHLYSIIA SCWHYSPDQR PSFTKLLQML 270

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity

KEGG

cin:100177957

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR008266	; Tyr_kinase_AS.
IPR020635	; Tyr_kinase_cat_dom.
IPR003306	; WIF.

Pfam

PF07714	; Pkinase_Tyr; 1.
PF02019	; WIF; 1.

SMARTs

SM00219

; TyrKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.
PS50814	; WIF; 1.

Prints

PR00109

; TYRKINASE.

Created Date

20-Feb-2013