EKS-CII-00008

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00008

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PHK	424.3	1.7E-127	25	290	266

Status

Unreviewed

Ensembl Protein

ENSCINP00000019808

UniProt Accession

F7ACA9;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100182979

Gene Synonyms/Alias

LOC100182979;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000009748	ENSCINP00000019808	ENSCINT00000019808

Organism

Ciona intestinalis

Functional Description

Protein Length

420

Protein Sequence
(FASTA)

MAVMDGEKKE ELPDINTAKE FYSKYEPKEI LGRGVSSCVR RCVDKKTRGE FAVKIIDLTD 60

GSNKISEELR QVTHNEINIL KEVSGHVHII ELVDVFETST FIFLIFQLLK RGELFDYLTE 120

VVKFGERQTR STMRSLLEAV AYLHSQNIVH RDLKPENILL DDDLNLHLSD FGFSTKIENG 180

KYFTELYGTP GYMSPEMLKC TVDEHHHGYG VEIDIWACGV IMYTLLAGAP PFWHRRQMIM 240

LRRIMEGQYS FPSPDWDDIS ESARDLVSKM LVVDPTKRLT AEMALAHPFF QQVEDTSRYS 300

AKPFNARRKF RVAVHTIVAY HRMAAQVHQH RPLQRAVAAR DPYSVKCLRR IIDASAFRIY 360

GHWVKKAANQ NRATLFENSS RADQRRLQEL EEFASAVNED GLLMCPISSA GNSLIPQSVS 420

Nucleotide Sequence
(FASTA)

ATGGCGGTCA TGGACGGTGA AAAAAAGGAG GAACTCCCTG ATATTAACAC TGCAAAAGAG 60

TTTTACAGCA AATATGAACC AAAGGAGATA TTGGGAAGGG GTGTAAGCAG CTGTGTGCGT 120

CGTTGTGTGG ACAAGAAAAC TCGCGGAGAA TTTGCCGTAA AGATCATTGA CTTAACTGAT 180

GGTAGTAATA AGATAAGTGA AGAGCTGAGA CAAGTCACAC ACAATGAAAT TAACATCCTC 240

AAAGAAGTCT CTGGTCATGT ACACATTATT GAACTGGTTG ATGTATTTGA AACAAGCACA 300

TTTATCTTCC TTATATTTCA ACTGTTAAAA CGTGGTGAAT TATTCGATTA TTTAACAGAG 360

GTGGTGAAAT TTGGAGAACG ACAGACCAGA TCCACAATGA GGTCTTTATT AGAAGCAGTT 420

GCTTACCTGC ATAGTCAGAA CATTGTACAC CGTGACCTTA AGCCTGAGAA TATTTTATTA 480

GATGACGACT TAAATCTACA TCTGTCGGAT TTCGGTTTTT CCACCAAGAT TGAAAATGGA 540

AAATATTTTA CAGAATTATA CGGCACACCC GGCTACATGT CTCCTGAGAT GTTAAAATGC 600

ACAGTAGACG AACATCACCA TGGTTATGGT GTTGAGATCG ATATTTGGGC GTGTGGTGTT 660

ATTATGTATA CGCTTCTTGC AGGAGCTCCT CCTTTTTGGC ACAGAAGGCA AATGATAATG 720

TTACGTCGGA TCATGGAAGG ACAATATTCG TTTCCAAGTC CGGACTGGGA TGATATTTCA 780

GAATCTGCAC GAGATTTAGT CTCAAAGATG CTGGTAGTTG ACCCAACAAA AAGATTAACA 840

GCAGAGATGG CGCTCGCTCA TCCATTCTTC CAGCAAGTGG AAGACACCTC GAGATACTCA 900

GCCAAACCAT TCAACGCTAG ACGAAAGTTC AGGGTGGCAG TTCATACAAT CGTAGCATAC 960

CACCGCATGG CGGCGCAAGT GCACCAGCAC AGACCACTAC AACGTGCGGT TGCCGCTCGT 1020

GATCCCTATT CTGTGAAATG CCTTCGACGA ATAATAGACG CTTCAGCTTT TCGTATATAT 1080

GGCCACTGGG TAAAGAAAGC AGCGAACCAA AACCGGGCCA CGCTTTTTGA AAACAGCTCC 1140

CGCGCAGACC AGCGCAGACT TCAAGAACTA GAAGAATTTG CATCTGCAGT TAATGAAGAC 1200

GGTCTTCTTA TGTGTCCCAT ATCCTCCGCT GGAAACAGTT TAATCCCACA ATCTGTCTCC 1260

TAG 1263

Domain Profile

S: 1     yepkeilGrGvssvvrrciekatgqefavkiidvsaeklseeevkelreatlkeveilrq  60

         yepkeilGrGvss vrrc++k+t  efavkiid++ +  s++  +elr+ t +e++il++

Q: 25    YEPKEILGRGVSSCVRRCVDKKTRGEFAVKIIDLTDG--SNKISEELRQVTHNEINILKE  82

         9*********************************965..455667999************

S: 61    vsGhpsiiklkdvyesssflflvfdlmkkGelfdyltekvtlseketrkimralleavey  120

         vsGh +ii+l dv+e+s+f+fl+f+l+k+Gelfdylte+v + e++tr+ mr+lleav+y

Q: 83    VSGHVHIIELVDVFETSTFIFLIFQLLKRGELFDYLTEVVKFGERQTRSTMRSLLEAVAY  142

         ************************************************************

S: 121   lhaknivhrdlkpenillddneniklsdfGfstqleeGeklrelcGtpgylapeilkcsm  180

         lh++nivhrdlkpenilldd+ n++lsdfGfst++e+G+ ++el Gtpgy++pe+lkc++

Q: 143   LHSQNIVHRDLKPENILLDDDLNLHLSDFGFSTKIENGKYFTELYGTPGYMSPEMLKCTV  202

         ************************************************************

S: 181   deeapGyskevdlwalGvilytllaGsppfwhrkqllmlrlimeGkyqftspewddisee  240

         de++ Gy+ e+d+wa+Gvi+ytllaG+ppfwhr+q++mlr imeG+y+f sp+wddise+

Q: 203   DEHHHGYGVEIDIWACGVIMYTLLAGAPPFWHRRQMIMLRRIMEGQYSFPSPDWDDISES  262

         ************************************************************

S: 241   vkdliskllvvdpekrltaeealahpff  268

         ++dl+sk+lvvdp+krltae alahpff

Q: 263   ARDLVSKMLVVDPTKRLTAEMALAHPFF  290

         ***************************8

Domain Sequence
(FASTA)

YEPKEILGRG VSSCVRRCVD KKTRGEFAVK IIDLTDGSNK ISEELRQVTH NEINILKEVS 60

GHVHIIELVD VFETSTFIFL IFQLLKRGEL FDYLTEVVKF GERQTRSTMR SLLEAVAYLH 120

SQNIVHRDLK PENILLDDDL NLHLSDFGFS TKIENGKYFT ELYGTPGYMS PEMLKCTVDE 180

HHHGYGVEID IWACGVIMYT LLAGAPPFWH RRQMIMLRRI MEGQYSFPSP DWDDISESAR 240

DLVSKMLVVD PTKRLTAEMA LAHPFF 266

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005964	; C:phosphorylase kinase complex
GO:0005524	; F:ATP binding
GO:0004689	; F:phosphorylase kinase activity
GO:0005978	; P:glycogen biosynthetic process

KEGG

cin:100182979

;

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR002291	; Phosph_kin_gamma.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01049

; PHOSPHBKNASE.

Created Date

20-Feb-2013