EKS-CII-00173

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00173

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IKK	173.6	5.0E-51	17	172	156

Status

Unreviewed

Ensembl Protein

ENSCINP00000021745

UniProt Accession

Q4H3C1; F6U8P5;

Protein Name

Protein Synonyms/Alias

IkappaB kinase;

Gene Name

Ci-IKK-alpha/beta

Gene Synonyms/Alias

Ci-IKK-alpha/beta; ikk-alpha/beta;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000011366	ENSCINP00000021745	ENSCINT00000021991

Organism

Ciona intestinalis

Functional Description

Protein Length

172

Protein Sequence
(FASTA)

MLATRPPQRQ PMQCGEWTLI KILGSGGFGQ VSLWKNKQDV KLAVKQCKNQ LSRQNERRWR 60

KEVEMMQRLN HPSIVNFVEV PVEIQNAYVD HYVALGMEYC EAGDLRKFLT QPENCCGLPE 120

FQVRNILQDI GSAIEHLHER QLVHRDLKPE NIVMKEKEKN VFQFKIIDLG YA 172

Nucleotide Sequence
(FASTA)

ATGTTGGCGA CACGTCCCCC ACAAAGACAA CCCATGCAAT GTGGAGAGTG GACGCTAATA 60

AAGATCCTTG GTTCCGGGGG TTTTGGGCAA GTCTCGCTGT GGAAGAATAA GCAAGATGTT 120

AAACTAGCAG TCAAACAATG CAAGAATCAA CTGAGTAGAC AAAATGAAAG AAGATGGAGA 180

AAGGAGGTTG AAATGATGCA AAGACTAAAC CACCCCAGTA TTGTTAACTT TGTGGAAGTA 240

CCGGTGGAGA TACAAAACGC ATATGTTGAT CATTATGTGG CACTTGGTAT GGAGTATTGT 300

GAGGCAGGAG ATCTGAGGAA GTTCCTGACT CAGCCGGAAA ACTGTTGTGG ATTGCCAGAG 360

TTTCAAGTTC GAAATATTCT ACAAGACATC GGGTCGGCAA TCGAACATTT GCATGAGAGA 420

CAACTTGTAC ATAGAGATTT GAAGCCCGAG AATATTGTGA TGAAAGAAAA AGAAAAAAAT 480

GTGTTTCAAT TCAAGATAAT TGATCTTGGA TATGCA 516

Domain Profile

S: 1     WelkelLGeGafgnvikarnkktgekiavkvikeesslrprevqvrelevlrklnhkniv  60

         W+l ++LG G+fg+v  ++nk+ + k+avk++k+++s++++ ++ +e+e++++lnh+ iv

Q: 17    WTLIKILGSGGFGQVSLWKNKQ-DVKLAVKQCKNQLSRQNERRWRKEVEMMQRLNHPSIV  75

         9999****************86.889**********************************

S: 61    klvdveeel.nlasarlkvlvleyCsgGdlrkvLeepenayGLkesevlvvLsdvvaglr  119

         + v+v+ e+ n    +   l +eyC++Gdlrk L +pen++GL+e++v+ +L+d+ ++++

Q: 76    NFVEVPVEIqNAYVDHYVALGMEYCEAGDLRKFLTQPENCCGLPEFQVRNILQDIGSAIE  135

         ********9677777777799***************************************

S: 120   yLrenkivhRDlkPenivllkgedgksiykltDlGaa  156

         +L+e ++vhRDlkPeniv+ + e++   +k++DlG+a

Q: 136   HLHERQLVHRDLKPENIVMKEKEKNVFQFKIIDLGYA  172

         **********************999999*******98

Domain Sequence
(FASTA)

WTLIKILGSG GFGQVSLWKN KQDVKLAVKQ CKNQLSRQNE RRWRKEVEMM QRLNHPSIVN 60

FVEVPVEIQN AYVDHYVALG MEYCEAGDLR KFLTQPENCC GLPEFQVRNI LQDIGSAIEH 120

LHERQLVHRD LKPENIVMKE KEKNVFQFKI IDLGYA 156

Keyword

Complete proteome; Kinase; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>