EKS-CII-00053

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00053

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Tec	394.6	1.3E-118	125	376	252

Status

Unreviewed

Ensembl Protein

ENSCINP00000004763

UniProt Accession

F6PN33;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100184615

Gene Synonyms/Alias

LOC100184615;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000016914	ENSCINP00000004763	ENSCINT00000004763

Organism

Ciona intestinalis

Functional Description

Protein Length

390

Protein Sequence
(FASTA)

WFQRDMTRQR AEYLLKQDGK EGNFIVRNSS QPSVVYTLSI VTKGGQINGP AIVKHYHIRK 60

NQNDEFYLSE KHFLPTIKEL INYHKHNAGG LVTRLRQAPV SIAGNSQPAT HLFSNSHWEI 120

DINELQFMKE LGSGQFGVVQ LASIRGKQLV AVKIMKEGTM EEDHFIEEAE VMTKLTHPNL 180

VELYGVVVKQ RPICIVTEFM EEGCLLDYIR KHTHLQNHPE TLLDMSCQIC SAMKYLETNN 240

LIHRDLAARN CLVGKNMLVK VADFGLTRYV LDDEYTSSLG SKFPIKWAAP EVLNFTKFSS 300

KSDVWAFGIL MWELFTGGKM PYRALSNTEV VERVAVGHRL ERPQSCPHDV YLLMLKTWDM 360

EPEKRPSFEI LSMEIEDIVD IVNAACMPEG 390

Nucleotide Sequence
(FASTA)

TGGTTTCAGC GCGATATGAC TCGACAACGA GCCGAATATT TATTAAAGCA AGATGGAAAA 60

GAAGGGAATT TTATCGTTCG TAATTCATCC CAGCCCTCAG TGGTTTATAC TTTATCTATC 120

GTTACTAAAG GAGGACAAAT TAATGGACCA GCTATCGTGA AGCATTACCA TATAAGAAAA 180

AATCAAAATG ATGAATTTTA TCTTTCGGAA AAACATTTCT TGCCAACTAT AAAGGAATTG 240

ATCAACTACC ACAAACATAA CGCTGGAGGT TTAGTTACGA GGCTACGGCA AGCTCCAGTA 300

TCAATAGCGG GGAATTCCCA GCCAGCCACC CATCTGTTCA GCAACTCACA TTGGGAGATT 360

GATATCAACG AACTACAGTT CATGAAAGAA CTTGGAAGCG GACAGTTTGG TGTGGTTCAA 420

CTTGCATCAA TACGTGGCAA ACAACTGGTT GCTGTGAAAA TAATGAAGGA AGGGACGATG 480

GAGGAGGATC ATTTTATTGA AGAGGCCGAA GTTATGACTA AACTGACCCA CCCGAACCTT 540

GTTGAGTTAT ACGGGGTTGT CGTGAAACAG CGACCGATCT GTATTGTCAC TGAGTTTATG 600

GAAGAAGGTT GTTTGCTGGA TTATATTCGG AAACATACGC ACCTACAGAA CCATCCGGAA 660

ACTTTACTAG ATATGTCTTG CCAGATATGT TCTGCTATGA AATATCTTGA AACAAATAAT 720

TTAATTCATC GTGATCTGGC TGCAAGGAAT TGCTTGGTTG GGAAAAACAT GTTGGTGAAA 780

GTAGCCGACT TTGGTCTGAC CAGATATGTT CTTGATGATG AATACACCAG CTCGCTTGGG 840

AGCAAATTCC CCATCAAATG GGCGGCCCCG GAAGTTTTGA ACTTTACTAA ATTTAGCTCA 900

AAGTCGGATG TTTGGGCATT TGGAATTCTA ATGTGGGAAC TTTTTACAGG AGGCAAAATG 960

CCGTACAGAG CATTAAGCAA CACCGAGGTT GTAGAACGAG TTGCCGTCGG TCATCGGTTG 1020

GAACGACCAC AAAGTTGCCC TCATGATGTT TATCTACTTA TGTTGAAAAC ATGGGACATG 1080

GAGCCAGAAA AACGGCCGTC GTTTGAAATC CTTTCAATGG AAATTGAAGA TATTGTTGAC 1140

ATTGTGAATG CAGCGTGCAT GCCAGAGGGA 1170

Domain Profile

S: 1     ltllkelgsgqfgvvklgkwrakidvaikaikegamseedfieeakvmmklshpklvqly  60

         l ++kelgsgqfgvv+l   r+k+ va+k++keg+m e++fieea+vm+kl+hp+lv+ly

Q: 125   LQFMKELGSGQFGVVQLASIRGKQLVAVKIMKEGTMEEDHFIEEAEVMTKLTHPNLVELY  184

         689*********************************************************

S: 61    gvclkqkpiyivteylengcllnylrekkkkl.ekelllemckdvcegmeylerksfihr  119

         gv +kq+pi+ivte++e+gcll+y+r++ +   + e+ll+m  ++c +m+yle +++ihr

Q: 185   GVVVKQRPICIVTEFMEEGCLLDYIRKHTHLQnHPETLLDMSCQICSAMKYLETNNLIHR  244

         ***************************9886515689***********************

S: 120   dlaarnclvdeelvvkvsdfglaryvlddqyvssvgakfpvkwsppevlsyskyssksdv  179

         dlaarnclv+++++vkv+dfgl+ryvldd+y+ss g+kfp+kw++pevl+++k+ssksdv

Q: 245   DLAARNCLVGKNMLVKVADFGLTRYVLDDEYTSSLGSKFPIKWAAPEVLNFTKFSSKSDV  304

         ************************************************************

S: 180   wafgvlmwevfsegklpyekksnsevvekvsrglrlyrpklaskkvyevmkscwkekpee  239

         wafg+lmwe+f+ gk+py   sn+evve+v+ g+rl+rp+++++ vy +m + w+ +pe+

Q: 305   WAFGILMWELFTGGKMPYRALSNTEVVERVAVGHRLERPQSCPHDVYLLMLKTWDMEPEK  364

         ************************************************************

S: 240   rptfkellsale  251

         rp+f+ l  ++e

Q: 365   RPSFEILSMEIE  376

         *****9987775

Domain Sequence
(FASTA)

LQFMKELGSG QFGVVQLASI RGKQLVAVKI MKEGTMEEDH FIEEAEVMTK LTHPNLVELY 60

GVVVKQRPIC IVTEFMEEGC LLDYIRKHTH LQNHPETLLD MSCQICSAMK YLETNNLIHR 120

DLAARNCLVG KNMLVKVADF GLTRYVLDDE YTSSLGSKFP IKWAAPEVLN FTKFSSKSDV 180

WAFGILMWEL FTGGKMPYRA LSNTEVVERV AVGHRLERPQ SCPHDVYLLM LKTWDMEPEK 240

RPSFEILSME IE 252

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase; Tyrosine-protein kinase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR000980	; SH2.
IPR008266	; Tyr_kinase_AS.
IPR020635	; Tyr_kinase_cat_dom.

Pfam

PF07714	; Pkinase_Tyr; 1.
PF00017	; SH2; 1.

SMARTs

SM00252	; SH2; 1.
SM00219	; TyrKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.
PS50001	; SH2; 1.

Prints

PR00401	; SH2DOMAIN.
PR00109	; TYRKINASE.

Created Date

20-Feb-2013