EKS-CII-00093

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00093

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/RSK	319.1	2.2E-95	30	297	268

Status

Unreviewed

Ensembl Protein

ENSCINP00000029922

UniProt Accession

H2XJU0;

Protein Name

Protein Synonyms/Alias

Gene Name

rps6ka5

Gene Synonyms/Alias

rps6ka5;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000021826	ENSCINP00000029922	ENSCINT00000037212

Organism

Ciona intestinalis

Functional Description

Protein Length

813

Protein Sequence
(FASTA)

MDDFAAEEVV LSVTDANLTG HVEKVGLDSF ELLKVLGTGA YGKVFLVRKA CGHDMGQLYA 60

MKVLKKASIV TKQKTTEHTM TERQVLEAVR QSPFLVTLHY AFQTNSRLHL ILDYVNGGEM 120

FTHLNTREKF TEPEVQLFSA EILLALEHLH KLGIVYRDIK LENILLDSEG HVVLTDFGLS 180

KEFINKGDRT FSFCGTIEYM APEVIRSNGA GHDFAVDFWS LGVLMYELLT GASPFTVEGE 240

RNSQAEVSRR ILYKHPPLPK GLSSAALDVI LKLLDKNPKT RLGCGTTGVK EIKEHPYYKS 300

LDWEKVARKD VPAPFKPVIA NDMDTSNFAE EFTLMPVNYS PAPTPATNAS CPFKVDQGYS 360

FVSPSVVFGR QHVLSDDLLK PMSNSGRPSP SYLQKVAHAG RLTDSEFFTL YELDLDTEPL 420

GDGSFSVCRK CVELSTGREF AVKIISRRWE LQSMLELRSL SHCQGHPNIV KLYNVFQDKH 480

HTYIVMELLH GGELLSMIRD HPTFNEAEAS IIMKQIVSAV AFMHEKGIVH RDLKPENIIF 540

VQAPTDTNNN TMPASKQLHI KIVDFGFARL KPNTGAGASV ALSTPVFTLQ YAAPEVLQTS 600

GFVGTSNTPG YDESCDLWSI GVILYAVLSG AVPFVSDGQS LRASEIMTRI TKGEFTFDGL 660

SWQNVSEEAR RLVDGLLTVD PKKRLKISDL LASPWVQGAC APTTPLLSPC ILSPGHRATT 720

CFNATMKAYH LASKEGFQLS AVTNAPIAKR RNRKRTGKQR NGSDTRSSSG SNDSVVLTSS 780

TAATSSSSCS TPGASPVTSP AVELIFQLST SAL 813

Nucleotide Sequence
(FASTA)

ATGGACGATT TTGCTGCAGA AGAAGTTGTT CTATCTGTGA CTGATGCAAA TCTCACAGGC 60

CATGTTGAAA AAGTTGGTTT GGACAGCTTC GAATTGTTAA AAGTTTTGGG AACTGGAGCG 120

TATGGCAAAG TGTTCCTGGT TCGAAAAGCA TGCGGTCACG ACATGGGTCA ACTATATGCT 180

ATGAAAGTGT TAAAAAAAGC ATCAATTGTT ACAAAACAAA AAACAACAGA ACACACAATG 240

ACAGAACGAC AGGTATTAGA GGCTGTACGT CAGTCTCCAT TCTTAGTGAC ACTTCACTAT 300

GCATTTCAAA CCAACTCAAG ATTACATCTC ATTTTAGATT ATGTCAATGG TGGTGAAATG 360

TTCACTCATT TGAATACAAG GGAAAAGTTT ACTGAGCCAG AAGTTCAATT ATTTAGTGCT 420

GAGATATTAC TTGCATTGGA ACATCTGCAT AAACTTGGAA TCGTATACCG TGACATAAAA 480

TTGGAAAATA TTTTGTTGGA TTCTGAAGGT CACGTTGTTT TGACTGACTT TGGTTTGAGT 540

AAGGAGTTCA TAAATAAAGG AGACAGAACA TTCTCATTTT GTGGCACGAT TGAGTACATG 600

GCTCCTGAAG TCATTAGAAG TAACGGCGCC GGTCACGATT TTGCCGTTGA CTTCTGGAGT 660

CTTGGTGTTC TGATGTACGA GCTGTTGACA GGTGCTTCCC CTTTCACAGT AGAAGGAGAA 720

CGGAACTCTC AAGCTGAAGT ATCAAGGCGC ATTTTATACA AGCATCCTCC ACTACCAAAA 780

GGTCTTTCTT CTGCAGCGCT TGACGTGATT TTAAAACTTC TCGACAAAAA TCCAAAAACA 840

CGTCTTGGAT GTGGAACAAC AGGTGTCAAA GAAATAAAGG AACATCCGTA CTATAAGTCA 900

CTAGACTGGG AGAAAGTGGC GCGAAAAGAT GTCCCTGCAC CTTTTAAGCC AGTTATCGCA 960

AATGATATGG ACACAAGTAA CTTTGCTGAG GAATTTACTT TGATGCCCGT CAACTATTCC 1020

CCTGCACCAA CACCAGCCAC TAACGCCTCA TGCCCTTTTA AGGTAGACCA GGGTTATTCA 1080

TTCGTGTCCC CATCGGTTGT GTTTGGACGA CAGCACGTAC TTTCCGACGA TCTTCTAAAA 1140

CCAATGTCCA ATTCGGGTCG GCCTTCCCCA AGCTACTTAC AGAAGGTAGC ACACGCTGGC 1200

CGTTTGACTG ACAGCGAATT TTTTACGCTG TATGAATTGG ACTTGGACAC TGAACCATTG 1260

GGTGATGGAA GTTTTTCAGT TTGTAGGAAA TGTGTGGAAC TTTCTACCGG TCGAGAGTTT 1320

GCAGTGAAAA TTATTAGCCG AAGATGGGAA TTGCAGTCAA TGTTAGAACT CCGATCATTA 1380

TCTCACTGTC AGGGCCATCC GAATATTGTC AAACTCTACA ATGTATTTCA GGATAAGCAC 1440

CACACGTACA TCGTAATGGA GTTATTACAT GGTGGTGAAC TGCTATCCAT GATACGTGAC 1500

CACCCAACTT TCAACGAGGC GGAAGCGAGT ATTATCATGA AGCAAATCGT GTCTGCCGTC 1560

GCCTTCATGC ACGAAAAAGG AATTGTACAT CGGGATTTAA AACCAGAGAA CATTATATTC 1620

GTGCAAGCAC CAACTGACAC TAACAACAAT ACCATGCCAG CCTCGAAACA ACTCCATATA 1680

AAAATCGTGG ACTTCGGTTT TGCGAGGCTA AAGCCCAACA CCGGCGCTGG GGCTTCTGTC 1740

GCGCTCAGCA CTCCTGTTTT TACGCTACAA TACGCCGCCC CAGAAGTTTT ACAGACCTCC 1800

GGTTTTGTAG GAACGTCCAA TACACCTGGC TACGACGAGT CTTGCGACCT ATGGAGTATA 1860

GGTGTTATTT TGTACGCCGT CTTATCCGGA GCTGTTCCGT TTGTGAGCGA CGGGCAGAGT 1920

CTCAGAGCTT CGGAAATCAT GACTCGTATC ACGAAGGGGG AATTTACCTT CGATGGCCTG 1980

TCCTGGCAGA ACGTGTCGGA AGAAGCACGA AGACTCGTGG ACGGTCTTTT GACAGTGGAT 2040

CCAAAAAAGC GACTCAAAAT CTCCGACCTG CTCGCAAGCC CGTGGGTCCA AGGAGCGTGC 2100

GCCCCAACAA CACCACTTCT CAGTCCTTGC ATTCTTTCAC CAGGCCACCG AGCCACCACC 2160

TGCTTCAACG CCACGATGAA GGCTTACCAC CTCGCCAGCA AAGAAGGGTT TCAACTTAGT 2220

GCAGTTACGA ACGCACCAAT TGCAAAACGC CGGAACAGAA AACGTACAGG CAAGCAACGA 2280

AACGGCTCCG ACACGAGAAG CAGCAGCGGC TCGAACGACA GCGTAGTTCT GACGTCATCA 2340

ACAGCCGCCA CGTCATCATC CTCCTGCTCG ACGCCAGGAG CAAGTCCAGT GACGTCACCA 2400

GCGGTTGAGT TGATATTTCA ACTCAGCACC AGTGCTTTG 2439

Domain Profile

S: 1     fellkvlgkGaygkvflvrkvekkdtgklyavKvlkkaelvk..kkkertkeereiLeev  58

         fellkvlg+Gaygkvflvrk  ++d g+lya+Kvlkka++v+  k++e+t++er++Le+v

Q: 30    FELLKVLGTGAYGKVFLVRKACGHDMGQLYAMKVLKKASIVTkqKTTEHTMTERQVLEAV  89

         89**************************************9978999*************

S: 59    eh.pfivklheafqdekklylvlellkGgeLlerlkkkklfseeeasfilaelvlaleyl  117

         ++ pf+v+lh+afq++++l+l+l++++Gge++++l+ ++ f+e e++ + ae+ lale+l

Q: 90    RQsPFLVTLHYAFQTNSRLHLILDYVNGGEMFTHLNTREKFTEPEVQLFSAEILLALEHL  149

         ************************************************************

S: 118   HskgvvyrDLkpeNilldeeghvkltDfglakekiaeneekaysfcgTleyvaPevl..k  175

         H+ g+vyrD+k+eNilld+eghv+ltDfgl+ke i +++ +++sfcgT+ey+aPev+  +

Q: 150   HKLGIVYRDIKLENILLDSEGHVVLTDFGLSKEFI-NKGDRTFSFCGTIEYMAPEVIrsN  208

         *********************************99.999999***************766

S: 176   rkgydeavDlwslGvllyemLtGktPftgeerketlarilkgkfslklpaweelseeakd  235

           g+d avD+wslGvl+ye+LtG++Pft e +++++a++ +  +  + p  + ls++a d

Q: 209   GAGHDFAVDFWSLGVLMYELLTGASPFTVEGERNSQAEVSRRILYKHPPLPKGLSSAALD  268

         779***************************99988886666655555555566*******

S: 236   lvkklLkkdpakRlga...taeeikehkf  261

         ++ klL+k+p++Rlg+   +++eikeh++

Q: 269   VILKLLDKNPKTRLGCgttGVKEIKEHPY  297

         ****************9999*******99

Domain Sequence
(FASTA)

FELLKVLGTG AYGKVFLVRK ACGHDMGQLY AMKVLKKASI VTKQKTTEHT MTERQVLEAV 60

RQSPFLVTLH YAFQTNSRLH LILDYVNGGE MFTHLNTREK FTEPEVQLFS AEILLALEHL 120

HKLGIVYRDI KLENILLDSE GHVVLTDFGL SKEFINKGDR TFSFCGTIEY MAPEVIRSNG 180

AGHDFAVDFW SLGVLMYELL TGASPFTVEG ERNSQAEVSR RILYKHPPLP KGLSSAALDV 240

ILKLLDKNPK TRLGCGTTGV KEIKEHPY 268

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 2.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 2.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 2.
PS50011	; PROTEIN_KINASE_DOM; 2.
PS00108	; PROTEIN_KINASE_ST; 2.

Prints

Created Date

20-Feb-2013