EKS-CII-00239

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00239

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	399.5	5.0E-120	14	275	262

Status

Unreviewed

Ensembl Protein

ENSCINP00000034118

UniProt Accession

H2XWT4;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100175927

Gene Synonyms/Alias

LOC100175927;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000022737	ENSCINP00000034118	ENSCINT00000035900

Organism

Ciona intestinalis

Functional Description

Protein Length

526

Protein Sequence
(FASTA)

MISFRQENVE DFYDITEEIG SGQFAVVRKC IEKSTNKVCA AKFIKKKRAK ASRRGVTKED 60

IEREVKILSD VNHENILQLH EVFESNTEVV LILEMVAGGE LFDFLAEKEC LSEPEAIVFL 120

NQILSGMDYL HDRNIAHFDL KPENIMLYDK CEDPHRIKLI DFGLAHMIEP GQEYRNMHGT 180

PEFVAPEIIA FESIGLPADC WSIGVITYIL LSGCSPFLGD DKSETFENIT RVDYDFDDEY 240

FDGTSDLAKD FIQQFLIRDP RKRLTVKDSL NHPWIKSAAV LIPSWSTLEP TYQPPTPTEI 300

KQITSSESND ETNFDVQVTV EDGKSPSPLP LPKKSPTPYP GASPIPSPIP PESPKPTPIQ 360

VQVEPARKKD EKDVPALPTP ASIPIPVHHV QRSSAASSRS SSEEEFWSPR SLLESKGGRM 420

TTSLSKSRDL LQDLRKERGA LEKDLRVFSE SIPLMSDDSV VNLRQRMARR IAEMEDSFNN 480

FSDDRSRTRR QMKSLFGDDG QLDLLQKRFQ QSKARFRNLI DNTDLQ 526

Nucleotide Sequence
(FASTA)

ATGATTTCTT TTCGCCAAGA AAATGTAGAA GATTTTTATG ATATTACCGA AGAAATTGGC 60

AGTGGGCAAT TTGCGGTCGT GCGAAAATGC ATCGAAAAAT CAACGAACAA AGTTTGCGCC 120

GCCAAGTTCA TAAAAAAGAA GAGAGCAAAG GCCAGTAGAC GTGGGGTTAC AAAGGAAGAC 180

ATAGAACGTG AAGTTAAAAT TCTAAGTGAT GTAAATCATG AAAACATTCT TCAACTTCAT 240

GAAGTGTTTG AAAGCAACAC GGAAGTTGTG CTGATACTGG AAATGGTGGC AGGCGGGGAA 300

TTGTTTGATT TTCTCGCTGA AAAAGAATGT TTGTCGGAAC CTGAAGCCAT TGTGTTTCTC 360

AACCAAATAT TGAGCGGGAT GGATTATTTG CACGACAGAA ATATCGCACA CTTTGATTTA 420

AAGCCTGAGA ATATAATGTT GTATGATAAA TGTGAGGACC CACACCGTAT TAAACTCATT 480

GATTTTGGCC TGGCACATAT GATTGAACCT GGACAGGAGT ATCGCAACAT GCATGGCACT 540

CCCGAATTTG TTGCACCTGA AATCATTGCA TTTGAATCAA TAGGACTACC TGCTGACTGT 600

TGGAGTATTG GAGTTATAAC ATATATTTTA TTAAGCGGTT GTTCCCCTTT CCTCGGCGAC 660

GACAAATCCG AAACATTCGA GAATATAACT CGTGTCGATT ACGATTTCGA TGATGAATAT 720

TTCGACGGTA CGAGCGACCT CGCAAAGGAT TTCATTCAAC AGTTCCTTAT TCGCGATCCA 780

AGAAAAAGGC TCACAGTGAA AGACAGTCTC AACCATCCGT GGATAAAGAG TGCTGCTGTC 840

CTAATACCGT CTTGGTCAAC CCTGGAACCC ACATACCAGC CTCCTACACC AACAGAAATC 900

AAACAAATCA CGTCGAGCGA ATCGAACGAT GAAACAAACT TCGATGTCCA AGTTACAGTG 960

GAGGATGGAA AATCCCCTTC ACCGTTACCA CTGCCCAAAA AATCCCCAAC CCCTTACCCA 1020

GGTGCATCCC CTATTCCGTC ACCAATTCCA CCGGAATCCC CAAAACCCAC ACCGATCCAA 1080

GTCCAAGTCG AACCTGCTCG GAAAAAAGAC GAAAAAGATG TTCCTGCTCT TCCTACTCCT 1140

GCCAGCATCC CTATCCCTGT CCACCACGTC CAAAGATCAA GCGCAGCATC ATCAAGATCC 1200

TCAAGTGAAG AGGAGTTTTG GAGTCCTCGA TCTCTCTTAG AATCCAAGGG TGGGAGGATG 1260

ACAACATCCT TATCAAAGTC CAGAGATCTT CTTCAGGACC TCAGAAAAGA GCGAGGAGCT 1320

CTCGAGAAAG ATCTTCGTGT CTTCTCAGAG AGCATTCCTT TGATGTCGGA TGACTCTGTG 1380

GTAAACCTCC GGCAGAGAAT GGCTCGTAGG ATCGCCGAGA TGGAGGATAG CTTCAATAAC 1440

TTCTCGGATG ATCGTTCAAG GACAAGAAGA CAGATGAAAT CTTTGTTTGG CGACGATGGC 1500

CAACTTGATC TGCTGCAGAA GCGTTTCCAA CAGAGCAAAG CAAGGTTCCG CAATTTAATC 1560

GACAATACTG ACCTGCAGTG A 1581

Domain Profile

S: 2     etgkelgsGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeirs  61

         ++++e+gsG+favvrkc+ekst k  aakf+kk+r+k+srrgv++e+ierev++l+ ++

Q: 14    DITEEIGSGQFAVVRKCIEKSTNKVCAAKFIKKKRAKASRRGVTKEDIEREVKILSDVN-  72

         6789******************************************************9.

S: 62    epnvinlhevyenksdvililelvaGGelfdllaekeslseeeatellkqilegvkylhs  121

         ++n+++lhev+e++++v+lile+vaGGelfd+laeke+lse ea+ +l+qil+g+ ylh+

Q: 73    HENILQLHEVFESNTEVVLILEMVAGGELFDFLAEKECLSEPEAIVFLNQILSGMDYLHD  132

         ************************************************************

S: 122   kkivhldlkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefvaPeivnye  181

         ++i+h+dlkPeni+l dk  +  +iklidfGl++ ie g+e +++ GtPefvaPei+ +e

Q: 133   RNIAHFDLKPENIMLYDKCEDPHRIKLIDFGLAHMIEPGQEYRNMHGTPEFVAPEIIAFE  192

         *******************88889************************************

S: 182   plsletdmwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselakdfi  241

         +++l +d wsiGvityillsg sPflGd+k et+ ni++v++df++e+f+ +s+lakdfi

Q: 193   SIGLPADCWSIGVITYILLSGCSPFLGDDKSETFENITRVDYDFDDEYFDGTSDLAKDFI  252

         ************************************************************

S: 242   rrllvkdpekrltieeclehswl  264

         ++ l++dp+krlt++++l+h+w+

Q: 253   QQFLIRDPRKRLTVKDSLNHPWI  275

         **********************8

Domain Sequence
(FASTA)

DITEEIGSGQ FAVVRKCIEK STNKVCAAKF IKKKRAKASR RGVTKEDIER EVKILSDVNH 60

ENILQLHEVF ESNTEVVLIL EMVAGGELFD FLAEKECLSE PEAIVFLNQI LSGMDYLHDR 120

NIAHFDLKPE NIMLYDKCED PHRIKLIDFG LAHMIEPGQE YRNMHGTPEF VAPEIIAFES 180

IGLPADCWSI GVITYILLSG CSPFLGDDKS ETFENITRVD YDFDDEYFDG TSDLAKDFIQ 240

QFLIRDPRKR LTVKDSLNHP WI 262

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

cin:100175927

;

InterPros

IPR011009	; Kinase-like_dom.
IPR020675	; Myosin_light_ch_kinase-rel.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013