EKS-CII-00040

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CII-00040

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	300.7	1.2E-89	135	477	343

Status

Unreviewed

Ensembl Protein

ENSCINP00000036411

UniProt Accession

H2Y3C6;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCING00000023900	ENSCINP00000036411	ENSCINT00000031491

Organism

Ciona intestinalis

Functional Description

Protein Length

540

Protein Sequence
(FASTA)

MKHIVENYQN MFNDFFQCIP PAASEESSLY GDSPTSDSVG LIWTKFSKNY KAKVERTFGG 60

QTGDKLSRMN LKQCRGEINN LYSDIEKFTL GTSSLNDYSP WLAKFQSLQR SSKELEVPGQ 120

YDGKSRPLLE YHATITGFDD RVTMMTSIRK PCKIIMRGSN EKDFGFLIKG GEDLRQDQRI 180

QQIFVIFNQL LESDMGCRKR NLSMRTYQVI PISSKVGMIE WVDNVVPYIE FISQQAKRMN 240

CNSCITEPAR TWIPKNMVQK PPCETYGVLM QRGSYAQVVE KFKRAENMLP WDLFRQAYIR 300

LCANPESFVA LRKRFTSSYA VMCVTHWLLG IGDRHTSNFM LSLTTGEVVG IDFGHAFGSA 360

TEVLPVPELV PFRLTNQIIN LLSPHSAIHG ELRHVMVRCL SALRSRTDTI LPLLDVFVKD 420

PSVDWAKFGK RSRDQDQRYS DSDVESSDRV WYARRKMALT KKKLEGENPS SITCDELNHN 480

STITKFKKSY CCIASGDTKN IRFLMPKSGL SVSEQTDCLL DLATDPNVLG RMWVGWKPWI 540

Nucleotide Sequence
(FASTA)

ATGAAACATA TTGTGGAAAA TTATCAAAAC ATGTTTAACG ATTTCTTCCA GTGTATTCCC 60

CCTGCTGCTT CAGAAGAATC ATCACTTTAT GGAGATTCTC CAACCTCTGA TTCAGTTGGC 120

TTAATATGGA CAAAATTTTC TAAGAACTAC AAGGCAAAGG TTGAGAGAAC ATTTGGCGGA 180

CAAACTGGTG ACAAACTGTC AAGGATGAAT TTAAAACAAT GCAGGGGTGA GATCAACAAT 240

CTTTATTCGG ATATTGAAAA GTTTACCCTT GGAACATCTT CTCTTAATGA TTACAGTCCA 300

TGGTTGGCTA AGTTTCAATC TTTACAGAGG AGCAGCAAAG AACTTGAGGT TCCAGGCCAG 360

TATGATGGAA AAAGTCGTCC ACTCCTGGAG TATCACGCAA CAATCACGGG ATTTGATGAT 420

AGGGTCACGA TGATGACATC AATTCGTAAA CCATGCAAGA TTATTATGCG TGGATCAAAT 480

GAAAAAGATT TTGGATTTTT GATTAAAGGT GGTGAGGATT TACGTCAGGA CCAACGTATC 540

CAACAAATAT TTGTCATTTT TAACCAGTTG TTAGAGTCAG ACATGGGGTG TAGGAAGAGA 600

AACTTATCAA TGAGAACATA CCAGGTTATC CCAATAAGTT CAAAGGTTGG AATGATTGAA 660

TGGGTGGACA ATGTGGTTCC TTACATTGAA TTTATTTCAC AACAAGCAAA AAGAATGAAC 720

TGCAATTCTT GTATTACTGA ACCAGCAAGA ACTTGGATTC CAAAGAATAT GGTTCAAAAA 780

CCTCCTTGCG AAACATATGG AGTGTTAATG CAGCGCGGGA GCTATGCACA GGTAGTGGAG 840

AAATTTAAGA GAGCTGAAAA TATGTTGCCA TGGGACTTAT TCAGGCAAGC CTACATAAGG 900

TTATGTGCAA ATCCAGAGTC ATTTGTTGCT CTGCGCAAAC GTTTTACATC CTCATACGCT 960

GTCATGTGCG TCACTCATTG GTTACTTGGG ATCGGCGATC GTCACACTTC TAACTTCATG 1020

CTGTCATTGA CAACTGGAGA AGTTGTTGGC ATCGATTTTG GTCACGCCTT TGGTTCGGCA 1080

ACAGAGGTTC TTCCTGTGCC AGAATTGGTT CCATTCCGTT TAACAAACCA GATCATCAAC 1140

CTGCTGTCAC CACATTCAGC CATTCATGGC GAACTTCGCC ATGTTATGGT TCGATGCTTA 1200

TCTGCTCTCA GATCTCGTAC GGATACAATT CTACCGCTGT TGGATGTTTT TGTAAAAGAT 1260

CCTTCTGTGG ATTGGGCAAA ATTTGGAAAA CGAAGTCGTG ATCAGGACCA AAGGTACTCA 1320

GATAGTGATG TAGAGTCATC CGATAGAGTT TGGTATGCCA GGAGGAAAAT GGCACTCACC 1380

AAAAAGAAAC TTGAAGGCGA AAATCCTTCA TCCATAACAT GTGATGAATT GAACCACAAC 1440

AGCACAATAA CAAAGTTTAA GAAGTCGTAC TGCTGCATTG CATCTGGGGA CACTAAAAAT 1500

ATAAGATTTC TAATGCCAAA ATCGGGACTT AGTGTCTCAG AGCAAACAGA CTGTTTATTG 1560

GATTTGGCAA CCGATCCCAA TGTGCTTGGT CGAATGTGGG TTGGGTGGAA GCCTTGGATT 1620

TAA 1623

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         i gfd+rv++++s +kp k+++rGs++k + +L+kg eDlrqd+r++q+f + N+lL+ d

Q: 135   ITGFDDRVTMMTSIRKPCKIIMRGSNEKDFGFLIKGGEDLRQDQRIQQIFVIFNQLLESD  194

         789*********************************************************

S: 61    ketsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpi.syrykd  119

           +++r+L++rty+V+p+s+++g+iewv+n v+  e++ +  ++  ++ ++ i +   +

Q: 195   MGCRKRNLSMRTYQVIPISSKVGMIEWVDNVVPYIEFISQQAKR--MNCNSCItEPARTW  252

         **************************************855555..55544443222233

S: 120   lstvqarkpklkhlkls.........levfkevlenlvpkdllkklllekfpspeewfel  170

          ++++ +kp  +++            +e fk   en+ p dl++++ ++ + +pe++ +l

Q: 253   IPKNMVQKPPCETYGVLmqrgsyaqvVEKFKR-AENMLPWDLFRQAYIRLCANPESFVAL  311

         34555555555555333355999666666655.46789**********************

S: 171   rkaytrslAvislvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvP  230

         rk +t+s Av+++ ++ Lg+gdrh++n+++  +tgevv idfg+af++a+  l+vpe vP

Q: 312   RKRFTSSYAVMCVTHWLLGIGDRHTSNFMLSLTTGEVVGIDFGHAFGSATEVLPVPELVP  371

         ************************************************************

S: 231   FRLTrnivnalgv.tgveGvfrasceavlrvlreskeklltiLevflydplvdwkk....  285

         FRLT++i+n+l +   ++G +r  ++  l +lr+  +++l +L+vf++dp+vdw k

Q: 372   FRLTNQIINLLSPhSAIHGELRHVMVRCLSALRSRTDTILPLLDVFVKDPSVDWAKfgkr  431

         ***********972579***************************************8888

S: 286   ...kkktsketeeelaekakaealkikkllskvekaenavatrdll  328

            +++  ++ + e +++ ++ + k+  +++k+e+ ++  +t+d+l

Q: 432   srdQDQRYSDSDVESSDRVWYARRKMALTKKKLEGENPSSITCDEL  477

         8665666666667777788899999999999999999999998876

Domain Sequence
(FASTA)

ITGFDDRVTM MTSIRKPCKI IMRGSNEKDF GFLIKGGEDL RQDQRIQQIF VIFNQLLESD 60

MGCRKRNLSM RTYQVIPISS KVGMIEWVDN VVPYIEFISQ QAKRMNCNSC ITEPARTWIP 120

KNMVQKPPCE TYGVLMQRGS YAQVVEKFKR AENMLPWDLF RQAYIRLCAN PESFVALRKR 180

FTSSYAVMCV THWLLGIGDR HTSNFMLSLT TGEVVGIDFG HAFGSATEVL PVPELVPFRL 240

TNQIINLLSP HSAIHGELRH VMVRCLSALR SRTDTILPLL DVFVKDPSVD WAKFGKRSRD 300

QDQRYSDSDV ESSDRVWYAR RKMALTKKKL EGENPSSITC DEL 343

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xiphophorus maculatus"; ?>