EKS-CAJ-00160

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00160

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/RSK	360.9	9.6E-108	67	328	262

Status

Unreviewed

Ensembl Protein

ENSCJAP00000001669

UniProt Accession

F7CC19;

Protein Name

Protein Synonyms/Alias

Gene Name

RPS6KB2

Gene Synonyms/Alias

RPS6KB2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000000967	ENSCJAP00000001669	ENSCJAT00000001773
ENSCJAG00000000967	ENSCJAP00000001673	ENSCJAT00000001777

Organism

Callithrix jacchus

Functional Description

Protein Length

470

Protein Sequence
(FASTA)

MAAVFDLDLE TEEGSDCEGE PELSPADVCP LAELRAAGLE PVGHYEEVEL TESSVNLGPE 60

RIGPHCFELL RVLGKGGYGK VFQVRKVQGT NLGKIYAMKV LRKAKIVRNA KDTAHTRAER 120

NILESVKHPF IVELAYAFQT CGKLYLILEC LSGGELFTHL EREGIFLEDT ACFYLAEITL 180

ALGHLHSLGI IYRDLKPENI MLSSQGHIKL TDFGLCKESI HEGAVTHTFC GTIEYMAPEI 240

LVRSGHNRAV DWWSLGALMY DMLTGSPPFT AENRKKTMDK IIKGKLALPP YLTPDARDLV 300

KKFLKRNPSQ RIGGGPGDAA DVQKHPFFRH MNWDDLLARC VDPPFRPCLQ SEEDVSQFDT 360

RFTRQTPVDS PDDTALSESA DQAFLGFTYV APSVLDSLKE GFSFQPKLRS PRRLNSSPRA 420

PISPLKFSPF EGFRPSPSLP EPMASITAPL PIRPHPGTKK SKRGRGRPGH 470

Nucleotide Sequence
(FASTA)

ATGGCGGCCG TGTTTGATCT GGATTTGGAG ACCGAGGAAG GCAGCGACTG CGAGGGAGAG 60

CCAGAGCTCA GCCCCGCGGA CGTGTGTCCC CTTGCCGAGT TGAGGGCAGC TGGCCTGGAG 120

CCTGTGGGGC ACTATGAAGA GGTGGAGCTG ACTGAGAGCA GTGTGAACCT CGGCCCGGAG 180

CGCATCGGGC CCCACTGTTT TGAGCTGCTG CGTGTGCTGG GCAAGGGAGG CTATGGCAAG 240

GTGTTCCAGG TTCGAAAGGT GCAAGGCACC AACTTGGGCA AAATATACGC CATGAAAGTC 300

CTAAGGAAGG CCAAAATTGT GCGCAACGCC AAGGACACAG CACACACTCG GGCTGAGCGG 360

AACATTCTGG AGTCAGTGAA GCACCCCTTT ATTGTGGAAC TGGCCTATGC CTTCCAGACT 420

TGTGGCAAAC TCTACCTCAT CCTCGAGTGT CTCAGTGGTG GCGAGCTCTT CACGCATCTG 480

GAGCGAGAGG GCATCTTCCT GGAAGATACG GCCTGCTTCT ACCTGGCCGA GATCACGCTG 540

GCCCTGGGCC ATCTCCACTC CCTGGGCATC ATCTACCGGG ACCTCAAACC CGAGAACATC 600

ATGCTCAGCA GCCAGGGCCA CATCAAACTG ACCGACTTTG GACTCTGCAA GGAGTCGATC 660

CATGAGGGCG CTGTCACTCA CACCTTCTGC GGCACCATTG AGTACATGGC CCCTGAGATT 720

CTGGTGCGCA GTGGCCACAA CCGGGCTGTG GACTGGTGGA GCCTGGGGGC CCTGATGTAC 780

GACATGCTCA CTGGATCGCC ACCCTTTACT GCAGAGAACC GGAAGAAAAC CATGGATAAG 840

ATCATCAAGG GCAAGCTGGC GCTGCCCCCC TACCTCACCC CTGATGCCCG GGACCTTGTC 900

AAAAAGTTTC TGAAACGGAA TCCCAGCCAG CGGATTGGGG GTGGCCCAGG GGATGCTGCT 960

GATGTGCAGA AGCACCCCTT TTTCCGGCAC ATGAATTGGG ACGACCTTCT GGCCCGCTGC 1020

GTGGACCCCC CTTTCAGGCC CTGTCTGCAG TCAGAGGAGG ATGTGAGCCA GTTTGATACC 1080

CGCTTCACGC GACAGACGCC GGTGGACAGT CCCGATGACA CGGCCCTTAG CGAGAGTGCT 1140

GACCAGGCCT TCCTGGGCTT CACGTATGTG GCGCCGTCTG TCCTGGACAG CCTCAAGGAG 1200

GGCTTTTCCT TCCAGCCCAA GCTGCGCTCA CCCAGGCGCC TCAACAGCAG CCCTCGGGCC 1260

CCTATCAGCC CCCTCAAGTT CTCCCCCTTT GAGGGGTTTC GGCCTAGCCC CAGTCTGCCA 1320

GAGCCCATGG CCTCGATCAC CGCCCCTCTC CCCATCCGTC CCCACCCAGG GACCAAGAAG 1380

TCCAAGAGGG GCCGTGGGCG TCCAGGGCAC TAA 1413

Domain Profile

S: 1     fellkvlgkGaygkvflvrkvekkdtgklyavKvlkkaelvk..kkkertkeereiLeev  58

         fell+vlgkG+ygkvf+vrkv++++ gk+ya+Kvl+ka++v+  k++++t++er+iLe+v

Q: 67    FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRnaKDTAHTRAERNILESV  126

         89***************************************999****************

S: 59    ehpfivklheafqdekklylvlellkGgeLlerlkkkklfseeeasfilaelvlaleylH  118

         +hpfiv+l +afq+  klyl+le+l+GgeL+++l+++++f e++a+f+lae++lal +lH

Q: 127   KHPFIVELAYAFQTCGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH  186

         ************************************************************

S: 119   skgvvyrDLkpeNilldeeghvkltDfglakekiaeneekaysfcgTleyvaPevlkrkg  178

         s g++yrDLkpeNi+l+++gh+kltDfgl+ke+i +++  +++fcgT+ey+aPe+l r+g

Q: 187   SLGIIYRDLKPENIMLSSQGHIKLTDFGLCKESI-HEGAVTHTFCGTIEYMAPEILVRSG  245

         *********************************9.9999999******************

S: 179   ydeavDlwslGvllyemLtGktPftgeerketlarilkgkfslklpaweelseeakdlvk  238

         +++avD+wslG+l+y+mLtG++Pft+e+rk+t+++i kgk  l lp +  l+++a+dlvk

Q: 246   HNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGK--LALPPY--LTPDARDLVK  301

         ****************************************..9*****..**********

S: 239   klLkkdpakRlga...taeeikehkfl  262

         k+Lk++p++R+g    +a+++++h+f+

Q: 302   KFLKRNPSQRIGGgpgDAADVQKHPFF  328

         ***********99999*********97

Domain Sequence
(FASTA)

FELLRVLGKG GYGKVFQVRK VQGTNLGKIY AMKVLRKAKI VRNAKDTAHT RAERNILESV 60

KHPFIVELAY AFQTCGKLYL ILECLSGGEL FTHLEREGIF LEDTACFYLA EITLALGHLH 120

SLGIIYRDLK PENIMLSSQG HIKLTDFGLC KESIHEGAVT HTFCGTIEYM APEILVRSGH 180

NRAVDWWSLG ALMYDMLTGS PPFTAENRKK TMDKIIKGKL ALPPYLTPDA RDLVKKFLKR 240

NPSQRIGGGP GDAADVQKHP FF 262

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007165	; P:signal transduction

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR016238	; Ribosomal_S6_kinase.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013