EKS-CAJ-00473

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00473

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/MAPK	405.5	2.4E-121	55	347	293

Status

Unreviewed

Ensembl Protein

ENSCJAP00000046024

UniProt Accession

F7II28;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPK7

Gene Synonyms/Alias

MAPK7;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000001277	ENSCJAP00000047420	ENSCJAT00000053466
ENSCJAG00000001277	ENSCJAP00000047444	ENSCJAT00000062411
ENSCJAG00000001277	ENSCJAP00000046024	ENSCJAT00000062938
ENSCJAG00000001277	ENSCJAP00000045181	ENSCJAT00000058928
ENSCJAG00000001277	ENSCJAP00000002248	ENSCJAT00000002372
ENSCJAG00000001277	ENSCJAP00000003036	ENSCJAT00000003205

Organism

Callithrix jacchus

Functional Description

Protein Length

753

Protein Sequence
(FASTA)

MAELLKEEDS EDGSAEPPGP VKGEPAHTAA SVAAKNLALL KARSFDVTFD VGDEYEIIET 60

IGNGAYGVVS SARRRLTGQQ VAIKKIPNAF DVVTNAKRTL RELKILKHFK HDNIIAIKDI 120

LRPTVPYGEF KSVYVVLDLM ESDLHQIIHS SQPLTLEHVR YFLYQLLRGL KYMHSAQVIH 180

RDLKPSNLLV NENCELKIGD FGMARGLCTS PAEHQYFMTE YVATRWYRAP ELMLSLHEYT 240

QAIDLWSVGC IFGEMLARRQ LFPGKNYVHQ LQLIMMVLGT PSPAVIQAVG AERVRAYIQS 300

LPPRQPVPWE TVYPGADRQA LSLLGRMLRF EPSARISAAA ALRHPFLAKY HDPDDEPDCA 360

PPFDFAFDRE ALTRERIKEA IVAEIEDFHA RREGIRQQIR FQPSLQPVAS EPGCPDVEMP 420

SPWAPSGDCV MESPPPALPA CPGPAPDTID LTLQPPAAAS EPAPPKKEGA ISDNTKAALK 480

AALLKSLQSR LRDGPSAPLE APEPRKPVTA GASGGPSTDP LAGLVLSDND RSLLERWTRM 540

ARPPGPIALP AGPQSQPAGS TSGPVPQPAC PPPGPAPHPT GLPRPISVPA SLQVATSTSL 600

LAPQSLVPPP GLPGSSTPGV LPYFPSGLPP PDGGGAPQSS MSESPDVNLV TQQLSKSQVE 660

DPLPPVFSGT PKGSGAGYGV GFDLEEFLNQ SFDMGLADGP QDGQADSASL SASLLADWLE 720

GHGMNPADIE SLQREIQMDS PMLLADLPDL QDP 753

Nucleotide Sequence
(FASTA)

ATGGCCGAGC TCCTGAAGGA GGAAGACAGC GAGGACGGCT CTGCGGAGCC CCCCGGGCCC 60

GTGAAGGGCG AACCCGCCCA CACTGCTGCC TCTGTAGCGG CCAAGAACCT GGCACTGCTT 120

AAAGCCCGCT CCTTCGATGT GACCTTTGAC GTGGGCGACG AGTACGAGAT CATTGAGACT 180

ATAGGCAACG GGGCCTACGG AGTGGTGTCC TCCGCTCGCC GCCGCCTCAC CGGCCAGCAG 240

GTGGCCATCA AGAAGATCCC TAATGCTTTC GATGTGGTGA CCAATGCCAA GCGGACCCTC 300

AGGGAGCTGA AGATCCTCAA ACACTTCAAG CATGACAACA TCATCGCCAT CAAGGACATC 360

CTGAGGCCCA CTGTGCCCTA CGGCGAATTC AAATCTGTCT ATGTGGTCCT GGACCTGATG 420

GAGAGTGACC TGCATCAGAT CATCCACTCC TCACAGCCCC TCACGCTGGA ACACGTGCGG 480

TACTTCCTGT ACCAACTGCT GCGGGGCCTG AAGTACATGC ACTCGGCTCA GGTCATCCAC 540

CGTGACCTCA AGCCCTCCAA CCTATTGGTG AATGAGAACT GTGAGCTCAA GATTGGTGAC 600

TTTGGTATGG CTCGTGGCCT GTGTACCTCA CCCGCTGAAC ATCAGTACTT CATGACTGAG 660

TATGTGGCCA CTCGCTGGTA CCGTGCCCCC GAGCTCATGC TCTCTTTGCA TGAGTACACA 720

CAGGCTATTG ACCTCTGGTC TGTGGGCTGC ATCTTTGGTG AGATGCTAGC CCGGCGCCAG 780

CTCTTCCCGG GCAAAAACTA CGTACACCAG CTACAGCTCA TCATGATGGT TCTGGGTACC 840

CCATCACCAG CTGTGATTCA GGCTGTGGGG GCTGAGAGGG TACGGGCCTA TATCCAGAGC 900

TTGCCACCAC GCCAGCCTGT GCCCTGGGAG ACAGTGTATC CAGGTGCCGA CCGCCAGGCC 960

CTATCACTGC TGGGTCGCAT GCTGCGTTTT GAGCCCAGCG CCCGCATCTC AGCAGCTGCT 1020

GCCCTTCGCC ACCCCTTCCT AGCCAAGTAC CATGACCCTG ATGATGAGCC TGATTGTGCC 1080

CCGCCCTTTG ACTTTGCCTT TGACCGAGAA GCCCTCACTC GGGAGCGCAT TAAAGAGGCC 1140

ATTGTGGCTG AGATTGAGGA CTTCCATGCA AGGCGCGAGG GCATCCGCCA ACAGATTCGC 1200

TTCCAGCCTT CTCTGCAGCC TGTGGCTAGT GAGCCTGGCT GTCCAGATGT TGAGATGCCT 1260

AGCCCCTGGG CTCCCAGTGG GGACTGTGTC ATGGAGTCTC CCCCACCAGC CCTGCCAGCG 1320

TGCCCCGGCC CTGCACCTGA CACCATTGAT CTGACCCTGC AGCCACCCGC AGCAGCCAGT 1380

GAGCCTGCCC CACCGAAGAA AGAGGGTGCC ATCTCAGACA ACACTAAGGC TGCTCTCAAA 1440

GCTGCGCTGC TCAAGTCCTT GCAGAGCCGG CTCAGAGATG GCCCCAGCGC ACCCCTGGAG 1500

GCTCCTGAGC CTCGGAAGCC AGTGACAGCT GGAGCCTCTG GGGGCCCCTC CACTGACCCC 1560

CTGGCTGGAC TAGTACTCAG TGACAATGAC CGAAGCTTGT TGGAACGCTG GACTCGAATG 1620

GCCCGGCCCC CTGGCCCTAT AGCCCTACCC GCTGGCCCCC AATCACAGCC TGCAGGTTCC 1680

ACCTCTGGCC CTGTACCCCA GCCTGCCTGC CCACCCCCTG GCCCTGCACC CCACCCCACT 1740

GGCCTTCCTA GACCTATCTC TGTCCCTGCA TCACTCCAGG TTGCCACTTC TACCAGCCTC 1800

CTGGCTCCCC AGTCACTTGT GCCGCCCCCT GGGTTGCCTG GCTCCAGCAC CCCAGGAGTT 1860

TTGCCTTACT TCCCATCTGG CCTGCCACCT CCAGATGGAG GGGGAGCCCC TCAGTCTTCC 1920

ATGTCAGAGT CACCTGATGT CAACCTGGTG ACCCAGCAGC TATCTAAGTC ACAGGTGGAG 1980

GACCCCCTGC CCCCTGTGTT CTCAGGCACA CCAAAGGGCA GTGGGGCTGG CTACGGTGTT 2040

GGTTTTGACC TGGAGGAATT TTTAAACCAG TCTTTCGACA TGGGCTTGGC TGATGGGCCA 2100

CAGGATGGCC AGGCAGATTC AGCCTCACTC TCAGCCTCCC TGCTTGCTGA CTGGCTCGAA 2160

GGCCATGGTA TGAACCCTGC CGATATTGAG TCCCTGCAGC GTGAGATCCA GATGGACTCC 2220

CCAATGCTAC TGGCTGACCT GCCTGACCTC CAGGACCCCT GA 2262

Domain Profile

S: 1     yeslkplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkelkheNi  60

         ye ++++g+Gaygvv sa ++ t+++vaikk+ ++f+  t+akrtlRElk+lk++kh+Ni

Q: 55    YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNI  114

         77899*******************************************************

S: 61    iklldvftpeeeleelkdvYlvtelmetdLkkviksq.klsdehiklllyqilrglkylH  119

         i + d+++p+  + e+k+vY+v +lme+dL+++i+s+  l+ eh++++lyq+lrglky+H

Q: 115   IAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSqPLTLEHVRYFLYQLLRGLKYMH  174

         ***********************************9889*********************

S: 120   sanviHrDlKPsNllvnedcelkildFGlarsadkekekk...lteyvatrwYraPeill  176

         sa+viHrDlKPsNllvne+celki dFG+ar   ++  ++   +teyvatrwYraPe++l

Q: 175   SAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHqyfMTEYVATRWYRAPELML  234

         *******************************955444333489*****************

S: 177   slkeytkavDiWsvGCIlaElltgkplfpgkdeidqlekilevlgtpseeflkkieseea  236

         sl+eyt+a+D+WsvGCI++E+l++++lfpgk++++ql++i+ vlgtps  +++++  e++

Q: 235   SLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERV  294

         ************************************************************

S: 237   rnyikslpkkkkkdfeelfpkaseealdLleklLvldpdkRisveeaLehpYl  289

         r+yi+slp+++  ++e+++p a+++al Ll ++L ++p+ Ris++ aL+hp+l

Q: 295   RAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFL  347

         ***************************************************97

Domain Sequence
(FASTA)

YEIIETIGNG AYGVVSSARR RLTGQQVAIK KIPNAFDVVT NAKRTLRELK ILKHFKHDNI 60

IAIKDILRPT VPYGEFKSVY VVLDLMESDL HQIIHSSQPL TLEHVRYFLY QLLRGLKYMH 120

SAQVIHRDLK PSNLLVNENC ELKIGDFGMA RGLCTSPAEH QYFMTEYVAT RWYRAPELML 180

SLHEYTQAID LWSVGCIFGE MLARRQLFPG KNYVHQLQLI MMVLGTPSPA VIQAVGAERV 240

RAYIQSLPPR QPVPWETVYP GADRQALSLL GRMLRFEPSA RISAAAALRH PFL 293

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004707	; F:MAP kinase activity
GO:0000165	; P:MAPK cascade

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR003527	; MAP_kinase_CS.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS01351	; MAPK; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013