EKS-CAJ-00122

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00122

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NAK	315.2	7.5E-94	2	246	245

Status

Unreviewed

Ensembl Protein

ENSCJAP00000003494

UniProt Accession

F7GPJ3;

Protein Name

Protein Synonyms/Alias

Gene Name

GAK

Gene Synonyms/Alias

GAK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000001896	ENSCJAP00000003494	ENSCJAT00000003684
ENSCJAG00000001896	ENSCJAP00000003470	ENSCJAT00000003660

Organism

Callithrix jacchus

Functional Description

Protein Length

1105

Protein Sequence
(FASTA)

IQRLLSNEEE KNRAIIQEVC FMKRLSGHPN IVQFCSAASI GKEESDTGQA EFLLLTELCK 60

GQLVEFLKKM ESRGPLSCDT VLKIFYQTCR AVQHMHRQKP PIIHRDLKVE NLLVSNQGTI 120

KLCDFGSATT ISHYPDYSWS AQRRALVEEE ITRNTTPMYR TPEIIDLYSN FPIGEKQDIW 180

ALGCILYLLC FRQHPFEDGA KLRIVNGKYS IPPHDTQYTV FHSLIRAMLQ VNPEERLSIA 240

EVVHQLQEIA AARNVNPKSP ITELLEQNGG YGSAALSRGP PPPVGPAGSG YGGGLALAEY 300

DQPYGGFLDI LRGGTERLFT NLRDTSSKVI QSVANYAKGD LDISYITSRI AVMSFPAEGV 360

ESALKNNIED VRLFLDSKHA GHYAVYNLSP RTYRPSRFHN RVSECGWAAR RAPHLHTLYN 420

ICRNMHAWLR QDHKNVCVVH CMDGRAASAV AVCSFLCFCR LFSTAEAAVY MFSMKRCPPG 480

IWPSHKRYIE YMCDMVAEEP ITPHSKPILV RAVVMTPVPL FSKQRSGCRP FCEVYVGDER 540

VASTSQEYDK MRDFKIEDGK AVIPLGITVQ GDVLIVIYHA RSTLSGRLQA SMASMKMFQI 600

QFHTGFVPRN ATTVKFAKYD LDACDIQEKY PDLFQVNLEV EVEPRDRPSR EAPPWENSSM 660

KGLNPKILFS SREEQQDILS KFGKPELPRQ PGSTAQYDAG VGSPEAEPPD SDSPPSSSAD 720

TSRFLHTLDW QEEKESETGA EDASPKESES ALMEDRDESE VSDEGGSPIS SEGQEPRADS 780

DTPCLAAGLV PQDSVLEVGS PAELPEPETQ EDGVDLLGLH SKPEAGAEPA LPPQAHRAPS 840

SNTDLLSCLL GSPEAASQGS PEDLLGEAPL LLASPAPPLS VQSTPRGGPP TAADPFGPLL 900

LSSDTDAQPC SSPDLFCELL NSDSAAVPSF PSAHSAPPLA CSTDFLHLGD LPGEPTKITA 960

SSSNPDLLGG WAAWAEAAAS ATTPVPATEG MTTPICRPIP CTTPASLTHK SNRPFKDMWV 1020

LGAGVQGSPA GFPPGSFVPK TAATPKASGS WQTSRSPAQG TPRPPQAKPP PKASTQLRPN 1080

YAANFSVIGA REERGVRAPS FGESP 1105

Nucleotide Sequence
(FASTA)

ATACAGAGGC TATTATCCAA CGAAGAGGAA AAGAACAGAG CCATCATTCA AGAAGTGTGT 60

TTCATGAAAA GGCTTTCCGG GCACCCGAAT ATCGTCCAGT TTTGTTCTGC AGCATCCATA 120

GGGAAAGAGG AGTCAGACAC GGGGCAGGCT GAGTTCCTCC TGCTCACGGA GCTCTGTAAA 180

GGGCAGCTGG TGGAATTTTT AAAGAAAATG GAGTCTCGAG GTCCGCTGTC ATGTGACACG 240

GTTCTGAAGA TCTTCTACCA GACGTGCCGG GCGGTGCAGC ACATGCACCG GCAGAAGCCG 300

CCCATCATCC ACCGGGACCT CAAGGTTGAG AATTTGTTAG TTAGTAACCA AGGGACCATC 360

AAGCTGTGTG ACTTTGGCAG CGCCACGACC ATCTCTCACT ACCCTGACTA CAGCTGGAGT 420

GCGCAGAGGC GAGCCCTGGT GGAGGAAGAG ATCACGAGGA ATACGACGCC AATGTACAGG 480

ACGCCGGAAA TCATAGACTT GTATTCGAAC TTCCCCATCG GCGAGAAGCA GGATATCTGG 540

GCCCTGGGCT GCATCTTGTA CCTGCTCTGC TTCCGGCAGC ACCCTTTTGA AGATGGAGCG 600

AAACTTCGAA TAGTCAACGG GAAGTACTCA ATCCCCCCGC ACGACACGCA GTACACGGTC 660

TTCCACAGCC TCATCCGCGC CATGCTGCAG GTGAACCCAG AGGAGCGGCT GTCCATCGCT 720

GAGGTGGTGC ATCAGCTGCA GGAGATCGCG GCCGCCCGCA ATGTGAACCC CAAGTCTCCT 780

ATCACAGAGC TCCTGGAGCA GAATGGAGGC TACGGGAGCG CCGCACTGTC CCGGGGGCCA 840

CCCCCTCCCG TGGGCCCCGC AGGCAGTGGC TACGGTGGAG GCCTGGCCCT GGCGGAGTAT 900

GACCAGCCCT ATGGCGGCTT CCTGGACATT CTGCGGGGTG GGACGGAGCG GCTTTTCACC 960

AACCTCAGGG ACACCTCGTC CAAGGTCATA CAGTCTGTTG CCAATTACGC CAAGGGTGAC 1020

CTGGACATAT CTTACATCAC ATCCAGGATT GCGGTGATGT CATTCCCAGC CGAAGGTGTG 1080

GAGTCAGCGC TCAAAAACAA CATTGAAGAT GTGCGGCTCT TCCTGGACTC GAAGCATGCA 1140

GGGCACTATG CCGTCTACAA CCTGTCCCCA AGGACCTACC GGCCCTCCAG GTTTCACAAC 1200

CGGGTCTCCG AGTGTGGCTG GGCGGCGCGG CGGGCCCCAC ACCTGCACAC CCTCTACAAC 1260

ATCTGCAGGA ATATGCACGC CTGGCTGCGG CAGGACCACA AGAACGTCTG TGTGGTGCAC 1320

TGCATGGATG GGAGAGCTGC GTCTGCCGTG GCCGTCTGCT CCTTCCTGTG CTTCTGCCGT 1380

CTCTTCAGCA CCGCGGAGGC CGCCGTGTAC ATGTTCAGCA TGAAGCGCTG CCCACCAGGC 1440

ATCTGGCCGT CCCACAAAAG GTACATCGAG TACATGTGTG ACATGGTGGC GGAGGAGCCC 1500

ATCACGCCTC ATAGCAAGCC CATCCTGGTG AGGGCCGTGG TCATGACGCC CGTGCCACTG 1560

TTCAGCAAAC AGAGGAGCGG CTGCAGGCCC TTCTGCGAGG TCTACGTGGG GGACGAGCGC 1620

GTGGCCAGCA CCTCCCAGGA GTATGACAAG ATGCGGGATT TTAAGATCGA GGATGGGAAA 1680

GCAGTCATTC CCTTGGGCAT CACGGTGCAA GGAGACGTGC TCATCGTCAT CTATCACGCC 1740

CGGTCCACCC TGAGTGGTCG GCTGCAGGCC AGTATGGCAT CCATGAAGAT GTTCCAGATT 1800

CAGTTCCACA CGGGCTTTGT GCCTCGGAAT GCCACCACTG TGAAATTTGC CAAGTATGAC 1860

CTGGACGCGT GCGACATTCA GGAGAAATAC CCAGATTTAT TTCAAGTGAA CCTGGAAGTG 1920

GAGGTGGAGC CCAGGGACAG GCCAAGCCGG GAGGCCCCGC CATGGGAGAA CTCGAGCATG 1980

AAGGGGCTGA ACCCCAAGAT CCTGTTTTCC AGCCGGGAGG AGCAGCAAGA CATTCTGTCT 2040

AAGTTTGGGA AGCCAGAGCT CCCTCGACAG CCCGGCTCCA CGGCTCAGTA TGATGCTGGG 2100

GTGGGGTCCC CAGAAGCCGA GCCCCCGGAC TCTGACTCAC CACCAAGCAG CAGTGCGGAC 2160

ACCAGCCGCT TCCTGCACAC ACTGGACTGG CAGGAAGAGA AGGAGTCAGA GACCGGTGCA 2220

GAAGACGCCT CTCCCAAGGA GAGCGAGTCT GCCCTGATGG AGGACAGAGA CGAGAGCGAG 2280

GTGTCGGATG AAGGGGGGTC CCCGATCTCC AGCGAGGGCC AGGAGCCCAG GGCCGACTCG 2340

GACACCCCCT GCCTAGCAGC GGGGCTGGTG CCGCAGGACT CTGTTTTGGA GGTGGGATCG 2400

CCCGCTGAAC TGCCAGAGCC TGAGACGCAG GAAGACGGGG TCGACCTCCT GGGGCTGCAC 2460

TCCAAGCCCG AGGCAGGCGC AGAGCCTGCT CTCCCACCGC AGGCCCACAG GGCCCCCTCC 2520

AGCAACACCG ACTTGCTCAG CTGCCTCCTC GGGTCCCCTG AGGCCGCCTC GCAGGGGTCC 2580

CCGGAGGATC TGCTCGGCGA GGCCCCCCTA CTCCTGGCAA GCCCGGCCCC TCCCCTGAGC 2640

GTTCAGAGTA CCCCAAGAGG AGGGCCCCCC ACTGCTGCTG ACCCCTTCGG CCCACTGCTG 2700

CTGTCTTCAG ACACTGACGC TCAGCCCTGC TCCAGTCCTG ATCTCTTCTG CGAGCTTCTC 2760

AACTCAGACT CTGCGGCCGT CCCGTCCTTC CCGTCTGCCC ACAGCGCTCC GCCCCTGGCC 2820

TGCAGCACCG ACTTCCTGCA CCTGGGGGAT CTGCCAGGAG AACCCACCAA GATAACAGCC 2880

TCATCCAGCA ACCCCGACCT GCTGGGAGGA TGGGCTGCCT GGGCCGAGGC TGCGGCGTCA 2940

GCCACGACCC CCGTGCCGGC CACGGAAGGT ATGACCACCC CCATCTGTAG ACCCATCCCC 3000

TGTACCACAC CCGCGTCACT CACACACAAG TCTAACAGGC CATTCAAAGA CATGTGGGTG 3060

CTGGGTGCAG GTGTTCAGGG CTCACCAGCT GGATTCCCTC CCGGCAGCTT CGTTCCCAAA 3120

ACGGCTGCCA CACCCAAGGC CAGTGGCTCC TGGCAGACAA GTCGATCGCC AGCCCAGGGC 3180

ACCCCACGGC CCCCTCAGGC CAAGCCTCCC CCCAAAGCCA GCACACAGCT GAGGCCTAAC 3240

TATGCCGCCA ACTTCAGTGT GATCGGGGCA CGAGAGGAGC GGGGGGTCCG CGCACCCAGT 3300

TTCGGTGAGT CCCCT 3315

Domain Profile

S: 30    KrilvneeedleeikrEieimkklsghknivklv..dssvkeekdngskevlllleyckk  87

          r+l+neee++++i++E+++mk+lsgh+niv+++  +s  kee+d+g++e+lll+e+ck

Q: 2     QRLLSNEEEKNRAIIQEVCFMKRLSGHPNIVQFCsaASIGKEESDTGQAEFLLLTELCK-  60

         799*******************************877888999****************.

S: 88    gslvdllnkrlekgelseaeilkilldvtravaalHalsvpliHRDlkveNillsdegel  147

         g+lv++l+k++++g ls++++lki+++++rav+++H++++p+iHRDlkveN+l+s++g++

Q: 61    GQLVEFLKKMESRGPLSCDTVLKIFYQTCRAVQHMHRQKPPIIHRDLKVENLLVSNQGTI  120

         8***********************************************************

S: 148   vlcDlGSattaileve...skqelsalqeeieknttlsyrsPElidlysnlvideksDiW  204

         +lcD+GSatt+++ ++   s+q+++ ++eei++ntt++yr+PE+idlysn++i+ek+DiW

Q: 121   KLCDFGSATTISHYPDyswSAQRRALVEEEITRNTTPMYRTPEIIDLYSNFPIGEKQDIW  180

         ***************999999***************************************

S: 205   aLGcllYklcffesPfeesvklailngkysiPensryseklkslikkmlevdpeeRptia  264

         aLGc+lY lcf+++Pfe+++kl+i+ngkysiP+++++++ ++sli++ml+v+peeR++ia

Q: 181   ALGCILYLLCFRQHPFEDGAKLRIVNGKYSIPPHDTQYTVFHSLIRAMLQVNPEERLSIA  240

         ************************************************************

S: 265   qvlell  270

         +v+++l

Q: 241   EVVHQL  246

         **9986

Domain Sequence
(FASTA)

QRLLSNEEEK NRAIIQEVCF MKRLSGHPNI VQFCSAASIG KEESDTGQAE FLLLTELCKG 60

QLVEFLKKME SRGPLSCDTV LKIFYQTCRA VQHMHRQKPP IIHRDLKVEN LLVSNQGTIK 120

LCDFGSATTI SHYPDYSWSA QRRALVEEEI TRNTTPMYRT PEIIDLYSNF PIGEKQDIWA 180

LGCILYLLCF RQHPFEDGAK LRIVNGKYSI PPHDTQYTVF HSLIRAMLQV NPEERLSIAE 240

VVHQL 245

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR001623	; DnaJ_N.
IPR011009	; Kinase-like_dom.
IPR014019	; Phosphatase_tensin-typ.
IPR000719	; Prot_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR014020	; Tensin_phosphatase_C2-dom.

Pfam

PF00226	; DnaJ; 1.
PF00069	; Pkinase; 1.
PF10409	; PTEN_C2; 1.

SMARTs

SM00271

; DnaJ; 1.

Prosites

PS51182	; C2_TENSIN; 1.
PS50076	; DNAJ_2; 1.
PS51181	; PPASE_TENSIN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013