EKS-CAJ-00236

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00236

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE7	336.4	2.6E-100	132	383	252

Status

Unreviewed

Ensembl Protein

ENSCJAP00000003933

UniProt Accession

F7EJT6;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP2K5

Gene Synonyms/Alias

MAP2K5;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000002156	ENSCJAP00000003936	ENSCJAT00000004150
ENSCJAG00000002156	ENSCJAP00000003894	ENSCJAT00000004106
ENSCJAG00000002156	ENSCJAP00000003933	ENSCJAT00000004146

Organism

Callithrix jacchus

Functional Description

Protein Length

412

Protein Sequence
(FASTA)

MMDGHFPQSD VIGQVLPEAT TTAFEYEDED GDRITVRSDE EMKAMLSYYY STVMEQQVNG 60

QLIEPLQIFP RACKPPGERN IHGLKVNTRA GPSQHSSPAV SDALPSNSLK KSSAELKKIL 120

ANGQMNEQDI RYRDTLGHGN GGTVYKAYHV PSGKILAVKV ILLDITLELQ KQIMSELEIL 180

YKCDSSYIIG FYGAFFVENR ISICTEFMDG GSLDVYRKIP EHVLGRIAVA VVKGLTYLWS 240

LKILHRDVKP SNMLVNTRGQ VKLCDFGVST QLVNSIAKTY VGTNAYMAPE RISGEQYGIH 300

SDVWSLGISF MELALGRFPY PQIQKNQGSL MPLQLLQCIV DEDSPILPVG EFSEPFVHFI 360

TQCMRKQPKE RPAPEELMGH PFLVQFNDGN ATVVSMWVCR ALEERRSQQG SP 412

Nucleotide Sequence
(FASTA)

ATGATGGACG GTCACTTTCC CCAGAGCGAT GTGATAGGCC AGGTTCTGCC TGAAGCCACA 60

ACTACAGCAT TTGAATATGA AGATGAAGAT GGTGATCGAA TTACAGTGAG AAGTGATGAA 120

GAAATGAAGG CAATGCTGTC GTATTATTAT TCCACAGTAA TGGAACAGCA AGTAAATGGA 180

CAGTTAATAG AGCCTCTGCA GATATTTCCA AGAGCCTGCA AGCCTCCTGG GGAACGGAAC 240

ATACATGGCC TGAAGGTGAA TACTCGGGCT GGACCCTCTC AACACAGCAG CCCAGCAGTC 300

TCAGATGCCC TTCCAAGCAA TAGCTTAAAG AAGTCTTCTG CTGAACTGAA AAAAATATTA 360

GCCAATGGCC AGATGAATGA ACAAGACATA CGGTATCGGG ACACTCTTGG TCATGGCAAT 420

GGAGGCACAG TCTACAAAGC ATATCATGTC CCGAGCGGCA AAATACTAGC TGTAAAGGTC 480

ATACTACTAG ATATTACACT GGAACTTCAG AAGCAAATCA TGTCTGAATT GGAAATTCTT 540

TATAAGTGTG ATTCATCATA TATCATTGGA TTTTATGGAG CATTTTTTGT AGAAAATAGG 600

ATTTCAATAT GTACAGAATT CATGGATGGG GGATCTTTGG ATGTATATAG GAAAATCCCA 660

GAACATGTCC TTGGAAGAAT TGCAGTAGCA GTTGTTAAAG GCCTTACTTA TTTGTGGAGT 720

TTAAAGATTT TACATAGAGA CGTGAAGCCC TCCAATATGC TAGTAAACAC AAGAGGACAG 780

GTCAAGCTGT GTGATTTTGG AGTTAGCACT CAGCTGGTGA ATTCTATAGC CAAGACGTAT 840

GTTGGAACAA ATGCTTATAT GGCGCCTGAA AGAATCTCAG GGGAGCAGTA TGGAATTCAT 900

TCTGATGTCT GGAGCTTAGG AATCTCTTTT ATGGAGCTTG CTCTTGGGAG GTTTCCATAT 960

CCTCAGATTC AGAAAAACCA GGGATCTTTA ATGCCTCTCC AGCTTCTGCA GTGCATTGTT 1020

GATGAGGATT CGCCCATCCT TCCAGTTGGA GAGTTCTCGG AACCATTTGT ACATTTCATC 1080

ACTCAGTGCA TGCGAAAACA GCCGAAAGAA AGGCCAGCGC CTGAAGAATT GATGGGCCAC 1140

CCGTTCCTCG TGCAGTTCAA TGACGGAAAT GCCACTGTCG TGTCCATGTG GGTGTGCAGG 1200

GCGTTGGAGG AGCGGCGGAG CCAGCAGGGA TCCCCATGA 1239

Domain Profile

S: 3     kleelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyivk  62

           ++lG+Gngg+V+k+ h +sgkilavK i l+i+ e qkqi++ele+l k+ +s+yi++

Q: 132   YRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKC-DSSYIIG  190

         5679************************************************.*******

S: 63    fyGafvsegdvsicmelmdgtsldkvlkkvlekkkripekvlgkiavavvkaleylkekl  122

         fyGaf+ e+++sic+e+mdg+sld v++k       ipe+vlg+iavavvk+l+yl+ +l

Q: 191   FYGAFFVENRISICTEFMDGGSLD-VYRK-------IPEHVLGRIAVAVVKGLTYLW-SL  241

         ************************.6876.......9********************.78

S: 123   kiiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksavGtksYmaPEriegkkkYsvk  182

         ki+HRDvKPsN+Lvn++G+vKlCDFGvs+qlv+siAk++vGt++YmaPEri+g ++Y ++

Q: 242   KILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISG-EQYGIH  300

         *****************************************************.******

S: 183   sdvWslGltlvelatgrypyeklke......ilellkaivneeppklpeeefseefqefv  236

         sdvWslG++++ela gr+py++ ++      +l+ll++iv+e++p+lp  efse f++f+

Q: 301   SDVWSLGISFMELALGRFPYPQIQKnqgslmPLQLLQCIVDEDSPILPVGEFSEPFVHFI  360

         ***********************9999*********************************

S: 237   skClkkdekeRpklkellkhafi  259

         ++C++k++keRp  +el+ h+f+

Q: 361   TQCMRKQPKERPAPEELMGHPFL  383

         *********************96

Domain Sequence
(FASTA)

YRDTLGHGNG GTVYKAYHVP SGKILAVKVI LLDITLELQK QIMSELEILY KCDSSYIIGF 60

YGAFFVENRI SICTEFMDGG SLDVYRKIPE HVLGRIAVAV VKGLTYLWSL KILHRDVKPS 120

NMLVNTRGQV KLCDFGVSTQ LVNSIAKTYV GTNAYMAPER ISGEQYGIHS DVWSLGISFM 180

ELALGRFPYP QIQKNQGSLM PLQLLQCIVD EDSPILPVGE FSEPFVHFIT QCMRKQPKER 240

PAPEELMGHP FL 252

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000270	; OPR_PB1.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00564	; PB1; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00666	; PB1; 1.
SM00220	; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013