EKS-CAJ-00178

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00178

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PKC	438.7	1.6E-131	220	489	270

Status

Unreviewed

Ensembl Protein

ENSCJAP00000004555

UniProt Accession

F7C4A7;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100399514

Gene Synonyms/Alias

LOC100399514;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000002470	ENSCJAP00000004555	ENSCJAT00000004802

Organism

Callithrix jacchus

Functional Description

Protein Length

563

Protein Sequence
(FASTA)

DIMITHFEPS ISFEGLCNEV RDMCSFDNEQ LFTMKWIDEE GDPCTVSSQL ELEEAFRLYE 60

LNKDSELLIH VFPCVPERPG MPCPGEDKSI YRRGARRWRK LYCANGHTFQ AKRFNRRAHC 120

AICTDRIWGL GRQGYKCINC KLLVHKKCHK LVTIECGRHS LPPEPMMPMD QSSMHSDHAQ 180

TVIPYNPSSH ESLDQVGEEK EAMNTRESGK ASSSLGLQDF DLLRVIGRGS YAKVLLVRLK 240

KTDRIYAMKV VKKELVNDDE DIDWVQTEKH VFEQASNHPF LVGLHSCFQT ESRLFFVIEY 300

VNGGDLMFHM QRQRKLPEEH ARFYSAEISL ALNYLHERGI IYRDLKLDNV LLDSEGHIKL 360

TDYGMCKKEG LRPGDTTSTF CGTPNYIAPE ILRGEDYGFS VDWWALGVLM FEMMAGRSPF 420

DIVGSSDNPD QNTEDYLFQV ILEKQIRIPR SLSVKAASVL KSFLNKDPKE RLGCHPQTGF 480

ADIQGHPFFR NVDWDMMEQK QVVPPFKPNI SGEFGLDNFD SQFTNEPVQL TPDDDDIVRK 540

IDQSEFEGFE YINPLLMSAE ECV 563

Nucleotide Sequence
(FASTA)

GATATCATGA TAACACATTT TGAACCTTCC ATCTCCTTTG AGGGCCTTTG CAATGAGGTT 60

CGAGACATGT GTTCTTTTGA CAATGAACAG CTCTTCACCA TGAAATGGAT AGATGAGGAA 120

GGAGACCCGT GTACAGTGTC ATCTCAGTTG GAGTTAGAAG AAGCCTTTAG ACTTTATGAA 180

CTAAACAAGG ATTCTGAACT CTTGATTCAT GTGTTCCCTT GTGTACCAGA ACGTCCTGGA 240

ATGCCTTGTC CAGGAGAAGA TAAATCCATC TACCGTAGAG GTGCACGCCG CTGGAGAAAG 300

CTTTATTGTG CCAATGGCCA CACTTTCCAA GCCAAGCGTT TCAACAGGCG TGCTCACTGT 360

GCCATCTGCA CAGACCGAAT ATGGGGACTT GGACGCCAAG GATATAAGTG CATCAACTGC 420

AAACTCCTGG TTCATAAGAA GTGCCATAAA CTCGTCACAA TTGAATGTGG GCGGCATTCT 480

TTGCCACCGG AGCCAATGAT GCCCATGGAT CAGTCATCCA TGCATTCTGA CCATGCACAG 540

ACAGTAATTC CATATAATCC TTCAAGTCAT GAGAGTTTGG ATCAAGTTGG TGAAGAAAAA 600

GAGGCAATGA ACACCAGGGA AAGTGGCAAA GCTTCATCCA GTCTAGGTCT TCAGGATTTT 660

GATTTGCTCC GGGTAATAGG AAGAGGAAGT TATGCCAAAG TACTGTTGGT TCGATTAAAA 720

AAAACAGATC GTATTTATGC AATGAAAGTT GTGAAGAAAG AACTTGTTAA TGATGATGAG 780

GATATTGATT GGGTACAGAC AGAAAAGCAT GTGTTTGAGC AGGCATCCAA TCATCCGTTT 840

CTTGTTGGAC TCCATTCTTG CTTTCAGACA GAAAGCAGAT TGTTCTTTGT TATAGAGTAT 900

GTAAATGGAG GAGACCTAAT GTTTCATATG CAGCGACAAA GAAAACTTCC TGAAGAACAT 960

GCCAGATTTT ACTCTGCAGA AATCAGTCTA GCATTAAATT ATCTTCATGA GCGAGGGATA 1020

ATTTATAGAG ATTTGAAATT GGACAATGTG TTACTGGACT CCGAAGGGCA CATTAAACTC 1080

ACTGACTATG GCATGTGTAA GAAGGAAGGA TTACGGCCAG GAGATACAAC CAGCACTTTC 1140

TGTGGTACTC CTAATTACAT TGCTCCTGAA ATTTTAAGAG GAGAAGATTA TGGTTTCAGT 1200

GTTGACTGGT GGGCTCTTGG AGTGCTAATG TTTGAGATGA TGGCAGGAAG GTCTCCATTT 1260

GATATTGTTG GGAGCTCTGA TAACCCTGAC CAGAACACAG AGGATTACCT CTTCCAAGTT 1320

ATTTTGGAAA AACAAATTCG CATACCACGG TCTCTGTCTG TAAAAGCTGC AAGTGTTCTG 1380

AAGAGTTTTC TTAACAAGGA CCCAAAAGAA CGATTGGGTT GTCATCCTCA AACAGGATTT 1440

GCTGATATTC AGGGACACCC ATTCTTCCGA AATGTTGATT GGGATATGAT GGAGCAAAAG 1500

CAGGTGGTAC CTCCCTTTAA ACCAAACATT TCTGGGGAAT TTGGTTTGGA CAACTTTGAT 1560

TCTCAGTTTA CTAATGAACC TGTCCAGCTC ACTCCAGATG ATGACGACAT TGTGAGGAAG 1620

ATTGATCAGT CTGAATTTGA AGGTTTTGAG TATATCAATC CTCTTTTGAT GTCTGCAGAA 1680

GAATGTGTCT GA 1692

Domain Profile

S: 1     fellkvlGkGsfgkvllaelkktdelyaikvlkkdvvlqdddveltlvekrvlalaskkp  60

         f+ll+v+G+Gs++kvll++lkktd++ya+kv+kk++v++d+d++++++ek+v+++as++p

Q: 220   FDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHP  279

         89**********************************************************

S: 61    flvqlfscfqtedrlffvleyvnGGdlmfhiqkarklkeerarfyaaeiilalkflhekg  120

         flv l+scfqte+rlffv+eyvnGGdlmfh+q++rkl+ee+arfy+aei+lal++lhe+g

Q: 280   FLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERG  339

         ************************************************************

S: 121   iiyrdlkldnvlldaeGhikladfGlck.eeilegkttstfcGtPdyiaPeilkeeeygk  179

         iiyrdlkldnvlld+eGhikl+d+G+ck e++  g+ttstfcGtP+yiaPeil++e+yg+

Q: 340   IIYRDLKLDNVLLDSEGHIKLTDYGMCKkEGLRPGDTTSTFCGTPNYIAPEILRGEDYGF  399

         ***************************73689****************************

S: 180   svdwwalGvllyemlagqsPfe.........gededelfesilekevlyPkslskeavei  230

         svdwwalGvl++em+ag+sPf+         +++ed+lf++ilek++++P+sls++a+++

Q: 400   SVDWWALGVLMFEMMAGRSPFDivgssdnpdQNTEDYLFQVILEKQIRIPRSLSVKAASV  459

         ******************************99****************************

S: 231   lkglltkdpekrlGvk.eegeedikehaff  259

         lk++l+kdp++rlG++ ++g +di+ h+ff

Q: 460   LKSFLNKDPKERLGCHpQTGFADIQGHPFF  489

         ***************989***********9

Domain Sequence
(FASTA)

FDLLRVIGRG SYAKVLLVRL KKTDRIYAMK VVKKELVNDD EDIDWVQTEK HVFEQASNHP 60

FLVGLHSCFQ TESRLFFVIE YVNGGDLMFH MQRQRKLPEE HARFYSAEIS LALNYLHERG 120

IIYRDLKLDN VLLDSEGHIK LTDYGMCKKE GLRPGDTTST FCGTPNYIAP EILRGEDYGF 180

SVDWWALGVL MFEMMAGRSP FDIVGSSDNP DQNTEDYLFQ VILEKQIRIP RSLSVKAASV 240

LKSFLNKDPK ERLGCHPQTG FADIQGHPFF 270

Keyword

ATP-binding; Complete proteome; Kinase; Metal-binding; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase; Zinc; Zinc-finger.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005622	; C:intracellular
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0008270	; F:zinc ion binding
GO:0035556	; P:intracellular signal transduction

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR020454	; DAG/PE-bd.
IPR011009	; Kinase-like_dom.
IPR000270	; OPR_PB1.
IPR012233	; PKC_zeta.
IPR017892	; Pkinase_C.
IPR002219	; Prot_Kinase_C-like_PE/DAG-bd.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00130	; C1_1; 1.
PF00564	; PB1; 1.
PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00109	; C1; 1.
SM00666	; PB1; 1.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS00479	; ZF_DAG_PE_1; 1.
PS50081	; ZF_DAG_PE_2; 1.

Prints

PR00008

; DAGPEDOMAIN.

Created Date

20-Feb-2013