EKS-CAJ-00268

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00268

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PLK	416.5	9.0E-125	54	306	253

Status

Unreviewed

Ensembl Protein

ENSCJAP00000007745

UniProt Accession

F6XJB8;

Protein Name

Protein Synonyms/Alias

Gene Name

PLK3

Gene Synonyms/Alias

PLK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000004232	ENSCJAP00000007745	ENSCJAT00000008188
ENSCJAG00000004232	ENSCJAP00000007761	ENSCJAT00000008205

Organism

Callithrix jacchus

Functional Description

Protein Length

639

Protein Sequence
(FASTA)

MEPAAGFLSP RPFQRAAAPP SPSALPGPEL EMLAGLPASD PGRLITDPRS GRTYFKGRLL 60

GKGGFARCYE ATDTETGSAY AVKVIPQSRV AKPHQREKIL NEIELHRDLQ HRHIVRFSHH 120

FEDADNIYIF LELCSRKSLA HIWKARHTLL EPEVRYYLRQ ILSGLKYLHQ RGILHRDLKL 180

GNFFITENME LKVGDFGLAA RLEPPEQRKK TICGTPNYVA PEVLLRQGHG PEADVWSLGC 240

VMYTLLCGTP PFETADLKET YRCIKQVHYT LPASLSLPAR QLLAAILRAS PRDRPSIDQI 300

LRHDFFAKGY TPDRLPISSC VTVPDLTPPN PARSLFAKVT KSLFGRKKKK SKNHAEERDE 360

VSCLVSGLMR TSIGHQDARP EAPAASGPAP VSLVETAPED SSPCETLASS GDGVEEGLTV 420

ATVVESALCA LRNCVAFMPP AEHNPAPLAQ PEPLVWVSKW VDYSNKFGFG YQLSSRRVAV 480

LFNDGTHMAL SANRKTVHYN PTSTKHFSFS VGAVPRALQP QLGILQYFTS YMEQHLMKGG 540

DLPSVEEVEV PAPPLLLQWV KTDQALLMLF SDGTVQVNFY GDHTKLILSG WEPLLVTFVA 600

RNRSACTYLA SHLRQLGCSP DLRQRLRYAL RLLRDRSPA 639

Nucleotide Sequence
(FASTA)

ATGGAGCCCG CCGCCGGTTT CCTGTCCCCG CGCCCCTTCC AGCGTGCGGC AGCCCCACCC 60

TCTCCGAGTG CCTTGCCCGG ACCTGAGCTG GAGATGCTGG CCGGGCTACC GGCGTCAGAC 120

CCCGGGCGCC TCATCACGGA CCCGCGCAGC GGCCGCACTT ACTTCAAAGG CCGCTTGTTG 180

GGCAAGGGGG GCTTCGCCCG GTGCTACGAG GCTACTGACA CAGAGACTGG CAGCGCCTAC 240

GCTGTCAAAG TCATCCCACA GAGCCGCGTC GCCAAACCGC ATCAGCGTGA GAAGATCCTA 300

AATGAGATTG AGCTGCACCG AGACCTGCAG CACCGCCACA TCGTGCGTTT TTCGCACCAC 360

TTTGAGGATG CTGACAACAT CTACATTTTC CTGGAGCTCT GCAGCCGAAA GTCCCTGGCC 420

CACATCTGGA AGGCCCGCCA CACCCTGTTG GAGCCAGAGG TGCGATACTA CCTGAGGCAG 480

ATCCTTTCAG GCCTTAAGTA CTTGCACCAG CGAGGCATCT TGCACCGGGA CCTCAAGTTG 540

GGAAATTTTT TCATCACTGA GAACATGGAA TTGAAGGTGG GGGATTTTGG ACTGGCAGCC 600

CGGTTGGAGC CCCCAGAGCA GAGGAAGAAG ACCATCTGTG GCACCCCCAA CTATGTGGCT 660

CCAGAAGTGC TACTGAGACA GGGCCACGGC CCTGAGGCAG ATGTGTGGTC ACTGGGCTGT 720

GTCATGTACA CGCTGCTCTG TGGGACCCCT CCCTTTGAGA CAGCAGACCT GAAGGAGACA 780

TATCGCTGCA TCAAGCAGGT TCACTACACG CTGCCTGCCA GCCTCTCACT GCCTGCCCGG 840

CAGCTTCTGG CTGCCATCCT TCGGGCTTCA CCCCGAGACC GCCCCTCTAT TGACCAGATC 900

CTGCGCCATG ACTTCTTTGC CAAGGGCTAC ACCCCTGATC GACTCCCTAT CAGCAGCTGT 960

GTGACAGTCC CAGACCTGAC ACCCCCCAAC CCGGCTAGGA GTCTGTTTGC CAAAGTTACC 1020

AAGAGCCTCT TTGGCAGAAA GAAGAAGAAG AGTAAGAATC ATGCCGAGGA GAGGGATGAG 1080

GTCTCCTGTT TGGTGAGCGG TCTCATGCGC ACGTCCATTG GCCATCAGGA TGCCAGGCCA 1140

GAGGCTCCAG CAGCTTCTGG CCCAGCCCCT GTCAGCCTGG TAGAGACAGC ACCTGAAGAC 1200

AGCTCACCCT GTGAGACACT GGCAAGCAGT GGAGATGGAG TTGAAGAAGG TCTGACTGTG 1260

GCCACAGTGG TGGAGTCAGC CCTCTGTGCG CTGAGAAACT GTGTGGCCTT CATGCCCCCA 1320

GCGGAACATA ACCCGGCCCC CCTGGCCCAG CCAGAGCCTC TGGTGTGGGT CAGCAAGTGG 1380

GTTGACTACT CCAACAAGTT TGGCTTTGGG TATCAACTGT CCAGCCGCCG TGTGGCTGTG 1440

CTCTTCAATG ATGGCACACA TATGGCCCTG TCAGCCAATA GAAAGACTGT GCACTACAAC 1500

CCCACCAGCA CAAAGCACTT CTCCTTCTCT GTGGGTGCTG TGCCCCGGGC CCTGCAGCCT 1560

CAGCTGGGTA TCCTGCAGTA CTTCACCTCC TACATGGAGC AGCACCTCAT GAAGGGTGGA 1620

GATCTGCCCA GTGTGGAAGA GGTAGAGGTA CCTGCCCCGC CCTTGCTGCT GCAGTGGGTC 1680

AAGACGGATC AGGCTCTCCT CATGCTGTTT AGTGATGGCA CTGTCCAGGT GAACTTCTAC 1740

GGGGACCACA CCAAGCTGAT TCTCAGTGGC TGGGAGCCCC TCCTTGTGAC TTTTGTGGCC 1800

CGAAATCGTA GTGCTTGTAC TTACCTCGCT TCCCACCTTC GGCAGCTGGG CTGCTCCCCA 1860

GACCTGCGGC AGCGACTCCG ATATGCTCTG CGCCTGCTCC GGGACCGCAG CCCAGCGTAG 1920

Domain Profile

S: 1     yergkllGkGgfakcyelkdletkevfavkvvpksllakekqrekvekeieihrslkhkn  60

         y +g+llGkGgfa+cye++d+et++++avkv+p+s++ak++qrek+ +eie+hr+l+h++

Q: 54    YFKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRH  113

         789*********************************************************

S: 61    ivklyeffedkenvylvlelcsrrslaellkrrkaltepevryylrqivsglkylhekri  120

         iv+++++fed++n+y++lelcsr+sla+++k+r++l epevryylrqi+sglkylh++ i

Q: 114   IVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGI  173

         ************************************************************

S: 121   lhrdlklgnlflneelevkigdfGlatrlekeeerkktlcGtPnyiaPevlskkghslev  180

         lhrdlklgn+f++e++e+k+gdfGla+rle++e+rkkt+cGtPny+aPevl ++gh+ e+

Q: 174   LHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPEA  233

         ************************************************************

S: 181   diWslGcilytllvGkPPfetkelketyekikkaeyslPsslskeaksliakllkkePee  240

         d+WslGc++ytll+G+PPfet++lkety++ik+ +y+lP+sls +a++l+a++l+++P++

Q: 234   DVWSLGCVMYTLLCGTPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRD  293

         ************************************************************

S: 241   rpsleevlkdefl  253

         rps++++l+++f+

Q: 294   RPSIDQILRHDFF  306

         ************8

Domain Sequence
(FASTA)

YFKGRLLGKG GFARCYEATD TETGSAYAVK VIPQSRVAKP HQREKILNEI ELHRDLQHRH 60

IVRFSHHFED ADNIYIFLEL CSRKSLAHIW KARHTLLEPE VRYYLRQILS GLKYLHQRGI 120

LHRDLKLGNF FITENMELKV GDFGLAARLE PPEQRKKTIC GTPNYVAPEV LLRQGHGPEA 180

DVWSLGCVMY TLLCGTPPFE TADLKETYRC IKQVHYTLPA SLSLPARQLL AAILRASPRD 240

RPSIDQILRH DFF 253

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000959	; POLO_box_duplicated_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR020658	; Ser/Thr_kinase_Plk3.

Pfam

PF00069	; Pkinase; 1.
PF00659	; POLO_box; 2.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50078	; POLO_BOX; 2.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013