EKS-CAJ-00126

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00126

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Met	448.6	1.5E-134	1083	1344	262

Status

Unreviewed

Ensembl Protein

ENSCJAP00000008290

UniProt Accession

F7I635;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100401190

Gene Synonyms/Alias

LOC100401190;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000004544	ENSCJAP00000047225	ENSCJAT00000061329
ENSCJAG00000004544	ENSCJAP00000008298	ENSCJAT00000008770
ENSCJAG00000004544	ENSCJAP00000008263	ENSCJAT00000008735
ENSCJAG00000004544	ENSCJAP00000008287	ENSCJAT00000008759
ENSCJAG00000004544	ENSCJAP00000008290	ENSCJAT00000008762

Organism

Callithrix jacchus

Functional Description

Protein Length

1403

Protein Sequence
(FASTA)

MELLPPLPQS FLLLLLLPAN PTAGEDWQCP RTSYAASRNF DVKYVVPSFS AGGLVQAMVT 60

YEGENESAVF VAIRNRLHVL GPDLKSLQSL VTGPAGDPGC QTCVTCGPGP HGPPGDTDTK 120

VLVLEPALPA LVSCGSSLQG RCFLHELEPQ GTAVHLAAPA CLFSAHHNRP DDCPDCVASP 180

LGTRVTVVEQ GQASYFYVAS SLDASVAASF SPHSVSIRRL KADYSGFAPG FAALSVLPKY 240

LASYSIEYVH SFQSGAFVYF LTVQPTSMTD APRALHTRLA RLSATETELG DYRELVLDCQ 300

FAPKRRRRGA PEDSRPYPVL RVAHSAPVGA QLATELSIAE GQEVLFGVFV AGKDGSPGVG 360

PNSVVCAFPI DLLDTLIDQG VERCCESPVH PGLRRGLDFF QLPSFCPDPP VPEAPSHNTS 420

CRHYPLLVSS SFLRVDLFNG LLGAVQVTAL YVTRLDNVTV AHMGTSDGRI LQVELARSLN 480

YLLYVSNFSL GDNGQPVQRD VSRLGDHLLF ASGDQVFKVP IQGPGCHHFL TCGRCLRAQR 540

FMGCGWCGSM CGRQKECPSS WQMDHCPPKL TEFHPHSGPL RGSTRLTLCG SNFYLHPGGL 600

VPEGTHQVTV GQSPCRPLPK DSSKLRPVPR KDFVEEFECE LEPSDTQAEG PTNVSLTVTN 660

MPPGKHFRVD GTSMLRGFSF MKPVLTAVQP LFGPRAGGTR LTLEGQSLSV GTSRAVLVNG 720

TECLLEWVSE GQLLCTTPPG AMAASVPLSL QVGGARVPGS WTFQYREDPV VLSISPTCGY 780

INSHITICGQ HLTSAWHLVL SFHDGNKAVE SRQCERQLPE QQLCRLPVYV VQDHQGGVTG 840

NLSAWGDGAA GFTLPGFHFL PPPHPPSANI APLKPEEHAI KFEYIGLGAV ADCVGVNVTV 900

GGESCQHEFW GDIIVCPLPP SLRLGKDGAP LQVCVDGECR ILGRVVQPGP DGVPQSTLLG 960

VLLPLLLLVA ALATALVFSY WWQRKQLVLS PNLDDLASLD QTVGATYLPM LSSGSDYRSG 1020

LAIPATDGLD STTCVHGASF SDSEDEYCVP LLRKESIKLK DLDSALLAEV KDVLVPHQRV 1080

VTHSDQVIGK GHFGVVYHGE YIDQAQNQIQ CAIKSLSRIT EVQQVEAFLR EGLLMRGLNH 1140

PNVLALIGIM LPPEGLPHVL LPYMCHGDLL QSFVDALIPS NNPTVKDLIS FGLQVARGME 1200

YLAEQKFVHR DLAARNCMLD ESFTVKVADF GLARDILDKE YYSVRQHRHA RLPVKWMALE 1260

SLQSYRFTTK SDVWSFGVLL WELLTRGAPP YSHIDPFDLP HFLAQGRRLP QPEYCPDSLY 1320

QVMQQCWEAD PAVRPTFGAL VGEVEQIVSI LLGDHYVHLP ATYVNLGPST SHEMNVRPEQ 1380

LQSSPTQGSE HRPRPLSEPP RPT 1403

Nucleotide Sequence
(FASTA)

ATGGAGCTCC TCCCGCCACT GCCTCAGTCC TTCCTGTTGC TGCTGCTGCT GCCTGCCAAT 60

CCCACGGCGG GCGAGGACTG GCAGTGCCCA CGCACCTCCT ACGCGGCCTC CCGCAACTTT 120

GACGTGAAGT ATGTGGTGCC CAGCTTCTCC GCCGGAGGCC TGGTACAGGC CATGGTGACC 180

TATGAAGGCG AAAATGAGAG TGCCGTGTTT GTAGCCATAC GCAATCGCCT GCATGTGCTT 240

GGGCCTGACC TGAAGTCTCT TCAGAGCTTG GTCACGGGCC CTGCTGGTGA CCCTGGCTGC 300

CAGACATGTG TAACCTGTGG TCCAGGCCCC CACGGCCCTC CCGGTGACAC AGACACAAAG 360

GTGCTGGTGC TGGAGCCCGC GCTGCCTGCT CTGGTCAGTT GTGGCTCCAG CCTTCAGGGC 420

CGCTGCTTCC TGCATGAGCT AGAGCCCCAA GGGACAGCCG TGCATCTGGC AGCGCCAGCC 480

TGCCTCTTCT CAGCCCACCA TAACCGGCCC GACGACTGCC CCGACTGTGT TGCCAGCCCA 540

TTGGGCACCC GTGTGACTGT GGTAGAGCAA GGCCAGGCCT CCTACTTCTA CGTGGCATCC 600

TCATTGGATG CATCCGTGGC TGCCAGCTTC AGCCCACACT CAGTGTCTAT CAGGCGACTC 660

AAGGCCGACT ACTCGGGATT CGCACCGGGC TTTGCGGCAT TGTCAGTGCT GCCTAAGTAT 720

CTCGCATCTT ACAGTATTGA ATACGTGCAC AGTTTCCAAT CGGGAGCCTT CGTCTACTTC 780

CTGACTGTGC AGCCGACCAG CATGACGGAT GCTCCTCGTG CCCTGCACAC ACGCCTGGCA 840

CGGCTTAGCG CCACTGAGAC AGAGTTGGGT GACTATCGGG AGCTGGTCCT TGACTGCCAA 900

TTCGCTCCGA AACGCAGGCG CCGGGGGGCC CCAGAGGACA GTCGGCCCTA TCCAGTGCTG 960

CGGGTGGCCC ACTCTGCTCC AGTGGGTGCC CAACTTGCGA CTGAACTGAG CATTGCTGAG 1020

GGCCAGGAAG TGCTCTTTGG GGTCTTTGTT GCTGGCAAGG ATGGTAGCCC TGGCGTGGGC 1080

CCCAACTCTG TCGTCTGTGC CTTCCCCATT GACCTGCTGG ACACGCTAAT TGATCAGGGT 1140

GTGGAGCGCT GTTGTGAATC CCCAGTCCAT CCAGGCCTCC GGCGAGGCCT CGACTTCTTC 1200

CAGTTGCCCA GTTTTTGCCC CGACCCGCCT GTCCCGGAGG CCCCCAGCCA CAACACCAGC 1260

TGCCGCCACT ACCCTCTGCT GGTCAGTAGC AGCTTCTTAC GTGTGGACCT ATTCAATGGG 1320

CTACTGGGAG CAGTACAGGT CACTGCATTG TATGTGACAC GCCTTGACAA CGTCACCGTG 1380

GCACACATGG GCACATCAGA TGGGCGTATC CTGCAGGTGG AGCTGGCCAG GTCACTCAAT 1440

TACTTGTTGT ATGTGTCCAA CTTCTCACTG GGTGACAATG GGCAGCCGGT GCAGCGGGAT 1500

GTCAGTCGCC TTGGGGACCA CCTACTCTTT GCCTCTGGGG ACCAGGTTTT CAAGGTACCT 1560

ATCCAGGGCC CTGGCTGCCA CCACTTCCTC ACCTGTGGGC GTTGCCTGAG GGCACAGCGT 1620

TTCATGGGCT GTGGCTGGTG TGGGAGCATG TGTGGCCGAC AGAAGGAGTG TCCTAGCTCC 1680

TGGCAAATGG ACCACTGCCC GCCTAAGCTT ACTGAGTTCC ACCCCCACAG TGGACCTCTA 1740

AGGGGAAGTA CAAGGCTGAC CCTGTGTGGC TCCAACTTCT ACCTGCACCC TGGTGGTCTG 1800

GTGCCTGAGG GAACCCATCA GGTCACCGTG GGCCAAAGTC CATGCCGGCC ACTGCCCAAG 1860

GACAGCTCAA AACTCAGACC AGTGCCCCGG AAAGACTTTG TAGAGGAGTT TGAGTGTGAA 1920

CTGGAGCCCT CCGACACCCA AGCAGAGGGA CCTACCAACG TCAGCCTCAC CGTGACTAAC 1980

ATGCCACCAG GCAAGCACTT CCGGGTAGAT GGCACCTCCA TGCTGAGAGG CTTCTCTTTC 2040

ATGAAGCCAG TGCTGACAGC AGTGCAACCC CTCTTTGGCC CACGGGCAGG GGGCACCCGT 2100

CTCACTCTTG AAGGCCAGAG TCTGTCTGTA GGCACTAGCC GGGCTGTGCT GGTCAATGGG 2160

ACTGAGTGTC TGCTAGAATG GGTCAGTGAG GGGCAGCTTT TATGTACCAC ACCCCCTGGG 2220

GCCATGGCAG CCAGTGTCCC CCTTAGCCTG CAGGTGGGGG GTGCCCGGGT ACCTGGTTCC 2280

TGGACCTTCC AATACAGAGA AGACCCTGTC GTGCTAAGCA TCAGCCCCAC CTGTGGCTAC 2340

ATCAACTCCC ACATCACCAT CTGTGGCCAG CACCTAACCT CAGCGTGGCA CTTAGTGCTA 2400

TCATTCCATG ACGGGAATAA GGCAGTGGAG AGCAGGCAGT GTGAGAGGCA GCTTCCAGAG 2460

CAGCAGCTGT GCCGCCTGCC TGTTTATGTG GTCCAGGATC ACCAGGGAGG GGTGACAGGG 2520

AATCTGAGTG CCTGGGGAGA TGGAGCTGCT GGCTTTACAC TGCCTGGCTT TCACTTCCTA 2580

CCCCCACCCC ATCCACCCAG TGCCAACATA GCTCCACTGA AGCCTGAGGA GCATGCCATT 2640

AAGTTTGAGT ATATTGGGCT AGGCGCTGTG GCTGACTGTG TGGGTGTCAA CGTGACCGTT 2700

GGCGGTGAGA GCTGCCAGCA TGAGTTCTGG GGGGACATAA TTGTCTGCCC CCTGCCCCCA 2760

TCCCTGCGGC TTGGCAAGGA TGGTGCCCCA TTGCAGGTCT GTGTGGATGG TGAATGTCGC 2820

ATCCTGGGTA GAGTGGTGCA GCCAGGCCCA GATGGGGTCC CACAAAGCAC GCTCCTTGGT 2880

GTCCTGCTGC CTTTGCTGCT GCTTGTGGCT GCACTGGCCA CTGCACTGGT CTTCAGCTAC 2940

TGGTGGCAGA GGAAGCAGCT TGTTCTTTCT CCCAACTTGG ATGACCTGGC ATCCCTGGAC 3000

CAGACTGTTG GAGCCACATA CCTGCCTATG CTCTCTTCGG GCTCTGACTA CAGAAGTGGC 3060

CTTGCAATCC CTGCCACCGA TGGTCTGGAT TCCACCACTT GTGTCCATGG AGCATCCTTC 3120

TCTGATAGTG AGGATGAATA CTGTGTCCCA CTGCTGCGGA AAGAGTCCAT CAAGCTGAAG 3180

GACCTGGACT CTGCACTGTT AGCTGAGGTC AAGGATGTGC TGGTTCCTCA TCAGCGGGTG 3240

GTCACCCACA GTGACCAAGT CATTGGCAAA GGCCACTTTG GAGTTGTCTA CCATGGAGAA 3300

TACATAGACC AGGCCCAGAA TCAAATTCAA TGTGCCATCA AGTCACTAAG TCGCATCACA 3360

GAGGTGCAGC AGGTGGAGGC CTTCCTGCGA GAGGGGCTGC TCATGCGTGG CCTGAACCAC 3420

CCGAACGTGC TGGCTCTCAT TGGTATCATG TTGCCGCCTG AGGGCCTGCC CCATGTGCTG 3480

CTGCCCTATA TGTGCCACGG TGACCTGCTC CAGTCTTTTG TAGACGCGTT AATTCCTAGT 3540

AATAACCCCA CTGTGAAGGA CCTCATCAGC TTTGGACTGC AGGTAGCCCG TGGCATGGAG 3600

TACCTGGCAG AGCAGAAATT TGTGCACAGG GACCTGGCTG CACGGAACTG CATGCTGGAT 3660

GAGTCATTCA CAGTCAAGGT GGCTGACTTT GGTTTGGCCC GTGACATCCT GGACAAGGAG 3720

TACTATAGTG TTCGACAGCA TCGCCATGCT CGCCTACCTG TGAAGTGGAT GGCGCTGGAG 3780

AGCCTGCAGA GCTACAGATT TACCACCAAG TCTGATGTGT GGTCATTTGG TGTGCTGCTG 3840

TGGGAACTGC TGACACGGGG CGCCCCACCA TACTCCCACA TCGACCCTTT TGACCTCCCC 3900

CACTTCCTGG CCCAGGGTCG GCGCCTGCCC CAGCCTGAGT ATTGCCCTGA TTCTCTGTAC 3960

CAAGTGATGC AGCAATGTTG GGAGGCAGAC CCAGCAGTGC GACCCACCTT CGGAGCACTA 4020

GTGGGGGAAG TGGAGCAGAT AGTGTCCATC CTACTTGGGG ACCATTATGT GCACCTGCCA 4080

GCGACCTACG TGAACTTGGG CCCCAGCACC TCGCATGAGA TGAATGTGCG TCCAGAACAG 4140

CTGCAGTCCT CACCCACACA GGGCAGTGAA CACCGGCCCC GGCCCCTCTC GGAGCCTCCT 4200

CGGCCCACTT GA 4212

Domain Profile

S: 2     dkeeviGkGhfGvvykgelsdsaskkikvavksleritdiekveeflreglvmkeldhpn  61

         ++++viGkGhfGvvy+ge++d+a+++i++a+ksl+rit++++ve+flregl+m++l+hpn

Q: 1083  HSDQVIGKGHFGVVYHGEYIDQAQNQIQCAIKSLSRITEVQQVEAFLREGLLMRGLNHPN  1142

         789*********************************************************

S: 62    vlsllGialddeglplvvlpymkkGdl.ksfirn..eernltvkdllefalqvakgmeyl  118

         vl+l+Gi+l++eglp+v+lpym++Gdl +sf++   +++n+tvkdl++f+lqva+gmeyl

Q: 1143  VLALIGIMLPPEGLPHVLLPYMCHGDLlQSFVDAliPSNNPTVKDLISFGLQVARGMEYL  1202

         **************************735688765579**********************

S: 119   askkfvhrdlaarnclldekltvkvadfGlardvldkelyvveeerdarlpvkwlalesl  178

         a++kfvhrdlaarnc+lde++tvkvadfGlard+ldke+y+v+++r+arlpvkw+alesl

Q: 1203  AEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDKEYYSVRQHRHARLPVKWMALESL  1262

         ************************************************************

S: 179   qtfkqfttksdvwsfGvllwelltrgatpysevasfdltlylkegrrlrkpeycpdklyd  238

         q+++ fttksdvwsfGvllwelltrga+pys++++fdl ++l++grrl++peycpd+ly+

Q: 1263  QSYR-FTTKSDVWSFGVLLWELLTRGAPPYSHIDPFDLPHFLAQGRRLPQPEYCPDSLYQ  1321

         ****.*******************************************************

S: 239   vmlkcwkakpaerpqfsdlvsii  261

         vm++cw+a+pa rp+f  lv  +

Q: 1322  VMQQCWEADPAVRPTFGALVGEV  1344

         *****************999765

Domain Sequence
(FASTA)

HSDQVIGKGH FGVVYHGEYI DQAQNQIQCA IKSLSRITEV QQVEAFLREG LLMRGLNHPN 60

VLALIGIMLP PEGLPHVLLP YMCHGDLLQS FVDALIPSNN PTVKDLISFG LQVARGMEYL 120

AEQKFVHRDL AARNCMLDES FTVKVADFGL ARDILDKEYY SVRQHRHARL PVKWMALESL 180

QSYRFTTKSD VWSFGVLLWE LLTRGAPPYS HIDPFDLPHF LAQGRRLPQP EYCPDSLYQV 240

MQQCWEADPA VRPTFGALVG EV 262

Keyword

ATP-binding; Complete proteome; Disulfide bond; Kinase; Membrane; Nucleotide-binding; Phosphoprotein; Receptor; Reference proteome; Transferase; Transmembrane; Transmembrane helix; Tyrosine-protein kinase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016021	; C:integral to membrane
GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity
GO:0004872	; F:receptor activity
GO:0007275	; P:multicellular organismal development

KEGG

InterPros

IPR013783	; Ig-like_fold.
IPR014756	; Ig_E-set.
IPR002909	; IPT_TIG_rcpt.
IPR011009	; Kinase-like_dom.
IPR003659	; Plexin-like.
IPR016201	; Plexin-like_fold.
IPR002165	; Plexin_repeat.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001627	; Semaphorin/CD100_Ag.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR008266	; Tyr_kinase_AS.
IPR020635	; Tyr_kinase_cat_dom.
IPR015943	; WD40/YVTN_repeat-like_dom.

Pfam

PF07714	; Pkinase_Tyr; 1.
PF01437	; PSI; 1.
PF01403	; Sema; 1.
PF01833	; TIG; 3.

SMARTs

SM00429	; IPT; 3.
SM00423	; PSI; 1.
SM00630	; Sema; 1.
SM00219	; TyrKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.
PS51004	; SEMA; 1.

Prints

PR00109

; TYRKINASE.

Created Date

20-Feb-2013