EPS-CAJ-00012

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-CAJ-00012

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	121.3	6.3E-35	30	170	141

Status

Unreviewed

Ensembl Protein

ENSCJAP00000008367

UniProt Accession

F7HN10;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP12

Gene Synonyms/Alias

DUSP12;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000004609	ENSCJAP00000008367	ENSCJAT00000008849

Organism

Callithrix jacchus

Functional Description

Protein Length

341

Protein Sequence
(FASTA)

MLEAPGPSLG CELGNPSSAV RASCVGQMLE VQPGLYLGGA AAVAEPNHLR EAGITAVLTV 60

DSEEPSFKAG PGAEGLWRLF VPALDKPETD LLSHLDRCVA FIGQARAEGR GVLVHCHAGV 120

SRSVAMITAF LMKTDQLPFE KAYEKLQTLK PEAKMNEGFE WQLKLYQAMG YEVDTSSAIY 180

KQYRLQKVTE KYPELQNLPQ ELFAVDPTTV LQGLKDEILY KCRKCRRSLF RSSSILDHHE 240

GSGPIAFAHK RMTPSFKLTA GRQAQCTSYF IEPVQWMESA LLGVMDGQLL CPKCSAKLGS 300

FNWYGEQCSC GRWITPAFQI HKNRVDEMKI LPILGSQTRK I 341

Nucleotide Sequence
(FASTA)

ATGTTGGAGG CTCCGGGTCC GAGTCTTGGC TGCGAGCTCG GCAACCCCAG CAGCGCTGTT 60

AGAGCCAGCT GCGTGGGGCA GATGCTGGAA GTGCAGCCAG GACTGTATCT GGGTGGGGCC 120

GCGGCCGTCG CGGAGCCAAA CCACTTGAGG GAAGCGGGCA TCACGGCTGT GCTAACGGTG 180

GACTCGGAGG AGCCCAGCTT CAAGGCTGGG CCTGGGGCCG AGGGTCTATG GCGCCTCTTC 240

GTGCCAGCAC TGGACAAACC CGAGACTGAC CTGCTCAGCC ATCTGGACCG GTGCGTGGCC 300

TTCATCGGCC AGGCCCGCGC CGAGGGCCGT GGGGTGTTGG TGCATTGCCA TGCAGGAGTC 360

AGTCGAAGTG TGGCCATGAT AACTGCTTTT CTCATGAAGA CTGACCAACT TCCCTTTGAA 420

AAAGCCTATG AAAAGCTCCA GACTCTCAAA CCAGAGGCTA AGATGAATGA GGGGTTTGAA 480

TGGCAATTGA AATTATACCA GGCGATGGGA TATGAAGTGG ATACCTCTAG TGCAATTTAT 540

AAGCAATATC GTTTACAAAA GGTTACAGAG AAGTATCCAG AATTGCAGAA TTTACCTCAA 600

GAACTCTTTG CTGTTGACCC AACCACCGTT TTACAAGGAT TGAAAGATGA GATTCTCTAC 660

AAGTGTAGAA AGTGCAGGCG ATCATTATTT CGAAGTTCTA GTATTCTGGA TCACCATGAA 720

GGAAGTGGAC CTATAGCCTT TGCCCACAAG AGAATGACAC CATCTTTCAA GCTTACCGCA 780

GGGAGGCAAG CTCAATGTAC ATCTTACTTC ATTGAACCTG TACAGTGGAT GGAATCTGCT 840

TTGTTGGGAG TGATGGATGG ACAGCTTCTT TGTCCAAAAT GCAGTGCCAA ATTGGGTTCC 900

TTCAACTGGT ATGGTGAACA GTGCTCGTGT GGTAGATGGA TAACACCTGC TTTTCAAATA 960

CATAAGAATA GAGTGGATGA AATGAAAATA TTGCCTATTT TGGGATCACA AACAAGAAAA 1020

ATATGA 1026

Domain Profile

S: 4     eilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipvdDs  63

         e+ pglylg++a + +  +L+++git v+++  +   ++++P +   +g   + +p+ D+

Q: 30    EVQPGLYLGGAAAVAEPNHLREAGITAVLTVDSEEPSFKAGPGA---EGLWRLFVPALDK  86

         799***************************************86...5999999******

S: 64    dvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAieav  123

         ++tdll+++d++++fi +a+ +g+ vlvHC+aGvsRS+++++a+Lmk+ +l +++A+e++

Q: 87    PETDLLSHLDRCVAFIGQARAEGRGVLVHCHAGVSRSVAMITAFLMKTDQLPFEKAYEKL  146

         ************************************************************

S: 124   krkrpsiepnegfleQLlelekkl  147

         ++ +p++++negf +QL +++ ++

Q: 147   QTLKPEAKMNEGFEWQLKLYQAMG  170

         ********************9886

Domain Sequence
(FASTA)

EVQPGLYLGG AAAVAEPNHL REAGITAVLT VDSEEPSFKA GPGAEGLWRL FVPALDKPET 60

DLLSHLDRCV AFIGQARAEG RGVLVHCHAG VSRSVAMITA FLMKTDQLPF EKAYEKLQTL 120

KPEAKMNEGF EWQLKLYQAM G 141

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0008270	; F:zinc ion binding
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR016278	; DUSP12.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR007087	; Znf_C2H2.

Pfam

PF00782

; DSPc; 1.

SMARTs

SM00195

; DSPc; 1.

Prosites

PS50056	; TYR_PHOSPHATASE_2; 1.
PS50054	; TYR_PHOSPHATASE_DUAL; 1.
PS50157	; ZINC_FINGER_C2H2_2; 1.

Prints

Created Date

20-Feb-2013