EKS-CAJ-00200

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00200

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/LISK	415.9	1.4E-124	61	309	249

Status

Unreviewed

Ensembl Protein

ENSCJAP00000008740

UniProt Accession

F7HMD2;

Protein Name

Protein Synonyms/Alias

Gene Name

TESK2

Gene Synonyms/Alias

TESK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000004755	ENSCJAP00000008728	ENSCJAT00000009228
ENSCJAG00000004755	ENSCJAP00000008734	ENSCJAT00000009234
ENSCJAG00000004755	ENSCJAP00000008655	ENSCJAT00000009152
ENSCJAG00000004755	ENSCJAP00000008661	ENSCJAT00000009158
ENSCJAG00000004755	ENSCJAP00000008740	ENSCJAT00000009240
ENSCJAG00000004755	ENSCJAP00000008719	ENSCJAT00000009219

Organism

Callithrix jacchus

Functional Description

Protein Length

571

Protein Sequence
(FASTA)

MDRSKRNSIA GFPPRVERLE EFEGGGGGDG NVSQVGRVWP SSYRALISAF SRLTRLDDFT 60

CEKIGSGFFS EVFKVRHRAS GQVMALKMNT LSSNRANMLK EVQLMNRLSH PNILRFMGVC 120

VHQGQLHALT EYINSGNLEQ LLDSNLHLPW TVRVKLAYDI AVGLSYLHFK GIFHRDLTSK 180

NCLIKRDENG YSAVVADFGL AEKIPDVSMG SEKLAVVGSP FWMAPEVLRG EPYNEKADVF 240

SYGIILCEII ARIQADPDYL PRTENFGLDY DAFQHMVGDC PPDFLQLTFN CCNMDPKLRP 300

SFVEIGKTLE EILSHLQEED QERDRKLQPT AKGLLEKTPG VKRLSSLDDK IPHKSPCPRR 360

TIWLSRSQSD IFSRKPPRTV SVLDPYYRPR DGAARTPKVN PFSARQDLRG GKIKFFDLPS 420

KSVISLVFDL DAPGPGTMPL ADWQEPLAPP IRRWRSLPGS PEFLHQEACP FVCREESLSD 480

GPPPRLSSLK YRVKEIPPFR ASALPAAQDH EAMDCSSLQE ENGFGSRPQG TSPCSAGASE 540

EMEVEERPAG STPATFSTSG IGLQTQGKQD G 571

Nucleotide Sequence
(FASTA)

ATGGATCGGA GCAAACGGAA TTCAATTGCG GGATTTCCTC CACGTGTAGA GCGTCTTGAA 60

GAGTTTGAAG GAGGTGGTGG AGGAGATGGA AATGTGAGCC AGGTCGGAAG AGTTTGGCCA 120

TCTTCATATA GAGCTCTTAT AAGTGCCTTT TCCAGACTGA CGCGTTTGGA TGATTTCACC 180

TGTGAAAAAA TAGGGTCTGG CTTCTTTTCT GAAGTGTTCA AGGTACGACA CCGAGCTTCT 240

GGTCAGGTGA TGGCTCTTAA GATGAACACG TTGAGTAGTA ACCGGGCAAA CATGCTGAAA 300

GAAGTACAGC TCATGAATAG ACTCTCCCAT CCCAACATCC TTAGGTTCAT GGGTGTGTGT 360

GTTCATCAAG GACAACTGCA TGCACTTACA GAGTATATCA ACTCTGGGAA CCTGGAACAG 420

TTGCTAGACA GTAACCTGCA TTTGCCTTGG ACTGTGAGGG TAAAACTGGC CTATGACATA 480

GCAGTGGGCC TCAGCTACCT TCACTTCAAA GGCATTTTTC ATCGGGACCT CACATCTAAG 540

AACTGCCTGA TAAAGAGGGA TGAGAATGGT TACTCTGCAG TGGTAGCTGA CTTTGGCCTG 600

GCTGAGAAGA TTCCCGATGT CAGCATGGGG AGTGAGAAGC TGGCCGTGGT GGGCTCCCCA 660

TTCTGGATGG CACCTGAGGT TCTCCGAGGT GAGCCCTATA ATGAGAAGGC GGATGTGTTC 720

TCTTATGGTA TCATCCTCTG CGAGATCATC GCCCGCATCC AGGCCGATCC AGACTACCTT 780

CCCCGCACAG AGAATTTCGG GCTGGACTAT GATGCTTTCC AGCACATGGT GGGAGACTGT 840

CCCCCAGACT TTCTGCAGCT CACCTTCAAC TGCTGTAATA TGGACCCCAA ACTGCGCCCA 900

TCCTTTGTGG AGATTGGGAA GACCCTGGAG GAAATTCTAA GCCACTTACA GGAAGAAGAT 960

CAGGAGAGGG ATAGGAAGCT GCAGCCCACA GCCAAGGGAC TCTTGGAGAA AACACCTGGG 1020

GTGAAGCGAC TAAGCTCACT GGATGACAAG ATCCCCCACA AGTCACCATG CCCGAGACGT 1080

ACCATCTGGC TGTCTCGAAG CCAATCAGAC ATCTTTTCCC GAAAGCCCCC ACGTACAGTG 1140

AGCGTCTTGG ACCCATACTA CCGGCCACGA GATGGTGCTG CCCGCACCCC CAAAGTCAAC 1200

CCTTTTAGTG CTCGCCAGGA CCTCAGGGGG GGCAAGATCA AGTTTTTTGA CCTGCCCAGC 1260

AAGTCTGTCA TCTCTCTGGT ATTTGACTTG GATGCACCAG GGCCGGGAAC TATGCCCCTG 1320

GCTGACTGGC AGGAGCCCCT GGCCCCACCT ATTCGCCGGT GGCGTTCCTT GCCTGGTTCA 1380

CCTGAGTTCT TGCATCAAGA AGCTTGTCCA TTTGTGTGCC GGGAAGAATC GCTATCTGAT 1440

GGGCCCCCAC CACGCCTAAG TAGTCTCAAG TACAGAGTAA AAGAGATCCC ACCATTCCGG 1500

GCATCTGCCC TACCAGCTGC TCAAGACCAT GAGGCTATGG ACTGCTCCAG TCTCCAGGAA 1560

GAAAACGGTT TTGGGTCCAG GCCCCAGGGG ACCAGTCCAT GCTCTGCAGG TGCTTCTGAG 1620

GAGATGGAGG TAGAAGAAAG GCCAGCAGGC TCAACTCCAG CTACCTTCTC CACCTCAGGC 1680

ATAGGCCTGC AGACCCAGGG AAAGCAGGAT GGGTGA 1716

Domain Profile

S: 4     geklGkGffsevfkvthrasGevmvlkeliradeenrknllkevkllrklehpnvlkfiG  63

          ek+G+Gffsevfkv+hrasG+vm+lk  ++++++nr+n+lkev+l+++l+hpn+l+f+G

Q: 61    CEKIGSGFFSEVFKVRHRASGQVMALK--MNTLSSNRANMLKEVQLMNRLSHPNILRFMG  118

         59*************************..*******************************

S: 64    vlvkdkklhllteyiegGtlkellkskeslpwtqrvrlakdiasGlsylhskgiihrdln  123

         v+v++++lh+lteyi++G+l++ll+s+ +lpwt+rv+la+dia+Glsylh+kgi+hrdl+

Q: 119   VCVHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLT  178

         ************************************************************

S: 124   sknclvre...dksvvvadfGlarlvveerkkseklrslkkkdrkkrltvvGsPywmaPe  180

         skncl+++   ++s+vvadfGla          ek+++++++  +++l+vvGsP+wmaPe

Q: 179   SKNCLIKRdenGYSAVVADFGLA----------EKIPDVSMG--SEKLAVVGSPFWMAPE  226

         *******9887899*********..........9****9999..899*************

S: 181   vlkgksydekvdvfsfGivlceiiarveadPdylPrtedfgldvkafreklvaedcPeaf  240

         vl+g+ y+ek+dvfs+Gi+lceiiar++adPdylPrte+fgld++af++ +v+ dcP++f

Q: 227   VLRGEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQH-MVG-DCPPDF  284

         *************************************************.999.******

S: 241   lklavvccdldpesrpsfeelekkl  265

         l+l+++cc++dp+ rpsf+e+ k+l

Q: 285   LQLTFNCCNMDPKLRPSFVEIGKTL  309

         *********************9876

Domain Sequence
(FASTA)

CEKIGSGFFS EVFKVRHRAS GQVMALKMNT LSSNRANMLK EVQLMNRLSH PNILRFMGVC 60

VHQGQLHALT EYINSGNLEQ LLDSNLHLPW TVRVKLAYDI AVGLSYLHFK GIFHRDLTSK 120

NCLIKRDENG YSAVVADFGL AEKIPDVSMG SEKLAVVGSP FWMAPEVLRG EPYNEKADVF 180

SYGIILCEII ARIQADPDYL PRTENFGLDY DAFQHMVGDC PPDFLQLTFN CCNMDPKLRP 240

SFVEIGKTL 249

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase; Tyrosine-protein kinase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR008266	; Tyr_kinase_AS.

Pfam

PF07714

; Pkinase_Tyr; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.

Prints

PR00109

; TYRKINASE.

Created Date

20-Feb-2013