EKS-CAJ-00205

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00205

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/MAST	526.1	4.0E-158	374	647	274

Status

Unreviewed

Ensembl Protein

ENSCJAP00000008852

UniProt Accession

F7IHG3;

Protein Name

Protein Synonyms/Alias

Gene Name

MAST1

Gene Synonyms/Alias

MAST1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000004772	ENSCJAP00000008852	ENSCJAT00000009356
ENSCJAG00000004772	ENSCJAP00000008863	ENSCJAT00000009368
ENSCJAG00000004772	ENSCJAP00000008865	ENSCJAT00000009370

Organism

Callithrix jacchus

Functional Description

Protein Length

725

Protein Sequence
(FASTA)

MSDSLWTALS NFSMPSFPGG SMFRRTKSCR TSNRKSLILT STSPTLPRPH SPLPGHLGSS 60

PLDSPRNFSP NTPAHFSFAS SRRADGRRWS LASLPSSGYG TNTPSSTVSS SCSSQERLHQ 120

LPYQPTVDEL HFLSKHFGST ESITDEDGGR RSPAVRPRSR SLSPGRSPSS YDNEIVMMNH 180

VYKERFPKAT AQMEEKLRDF ARAYEPDSVL PLADGVLSFI HHQIIELARD CLTKSRDGLI 240

TTVYFYELQE NLEKLLQDAY ERSESLEVAF VTQLVKKLLI IISRPARLLE CLEFNPEEFY 300

HLLEAAEGHA KEGHLVKTDI PRYIIRQLGL TRDPFPDVVH LEEQDSGGSN TPEQDDLSEG 360

RSNKAKKPPG ENDFDTIKLI SNGAYGAVYL VRHRDTRQRF AMKKINKQNL ILRNQIQQAF 420

VERDILTFAE NPFVVGMFCS FETRRHLCMV MEYVEGGDCA TLLKNIGALP VEMARMYFAE 480

TVLALEYLHN YGIVHRDLKP DNLLITSMGH IKLTDFGLSK MGLMSLTTNL YEGHIEKDAR 540

EFLDKQVCGT PEYIAPEVIL RQGYGKPVDW WAMGIILYEF LVGCVPFFGD TPEELFGQVI 600

SDDILWPEGD EALPTEAQLL ISSLLQTNPL VRLGAGGAFE VKQHSFFRDL DWTGLLRQKA 660

EFIPHLESED DTSYFDTRSD RYHHVNSYDE DDTTEEEPVE IRQFSSCSPR FSKVYSACIH 720

MYTYK 725

Nucleotide Sequence
(FASTA)

ATGTCTGACT CCCTCTGGAC CGCGCTTTCC AATTTCTCGA TGCCCTCCTT CCCCGGCGGC 60

AGTATGTTCC GCCGCACCAA GAGCTGCCGC ACCAGTAACC GGAAAAGCCT CATCCTGACC 120

AGCACTTCGC CCACGCTGCC GAGACCCCAC TCCCCTCTAC CAGGCCATCT AGGCAGCAGT 180

CCCCTGGACA GCCCCCGAAA CTTCTCCCCC AACACCCCCG CTCACTTCTC GTTTGCCTCT 240

TCCAGAAGGG CGGACGGACG CCGGTGGTCT CTGGCCTCTC TCCCTTCATC TGGCTATGGC 300

ACCAACACAC CCAGCTCCAC CGTCTCGTCC TCCTGCTCCT CCCAGGAGCG CCTGCACCAG 360

CTGCCCTACC AGCCCACGGT GGACGAGCTC CACTTCCTCT CCAAACACTT TGGGAGCACG 420

GAGAGCATCA CAGACGAGGA TGGTGGCCGT CGCTCCCCAG CCGTGCGGCC CCGCTCGCGG 480

AGCCTCAGCC CCGGGCGCTC CCCCTCCTCC TACGACAACG AAATCGTGAT GATGAATCAT 540

GTCTACAAGG AGAGGTTCCC GAAGGCCACC GCGCAGATGG AGGAGAAGCT GCGCGATTTC 600

GCCCGCGCCT ATGAACCCGA CAGCGTTCTG CCGCTGGCCG ATGGCGTGCT CAGCTTCATC 660

CACCACCAGA TCATCGAGCT GGCCCGGGAC TGCCTGACCA AGTCCCGCGA CGGCCTCATA 720

ACCACCGTCT ACTTCTACGA ATTGCAGGAA AACCTGGAGA AGCTCCTTCA AGACGCTTAT 780

GAACGCTCTG AGAGCTTGGA GGTGGCCTTC GTCACTCAGT TGGTGAAGAA GTTGCTTATT 840

ATCATCTCAC GCCCTGCGAG GCTGCTGGAG TGCCTGGAAT TCAACCCCGA GGAGTTCTAC 900

CATCTGCTGG AGGCAGCCGA GGGACACGCC AAGGAGGGCC ACCTTGTCAA GACGGACATC 960

CCCCGTTACA TCATCCGCCA GCTGGGCCTC ACCCGTGACC CCTTTCCAGA CGTGGTGCAC 1020

CTGGAGGAAC AGGACAGTGG TGGCTCCAAC ACTCCTGAGC AAGACGATCT CTCCGAGGGC 1080

CGCAGCAACA AGGCCAAGAA ACCACCCGGG GAGAATGACT TTGATACCAT CAAGCTCATA 1140

AGCAATGGTG CCTACGGCGC TGTCTACCTG GTGCGGCACC GCGACACGCG GCAGCGCTTC 1200

GCCATGAAAA AGATCAACAA GCAGAACTTG ATCCTCCGCA ACCAGATCCA GCAGGCCTTC 1260

GTGGAGCGCG ACATCCTCAC CTTCGCCGAG AACCCGTTTG TGGTCGGCAT GTTCTGCTCC 1320

TTCGAGACCC GGCGCCACCT CTGCATGGTC ATGGAATATG TGGAAGGCGG CGACTGTGCC 1380

ACCCTGCTGA AGAATATCGG AGCGCTGCCC GTAGAGATGG CCCGCATGTA CTTTGCTGAG 1440

ACGGTACTAG CCCTGGAGTA TTTACACAAC TATGGCATCG TGCACCGCGA CCTCAAGCCT 1500

GACAACCTCC TTATCACCTC CATGGGTCAC ATCAAGCTCA CAGATTTCGG CCTCTCCAAG 1560

ATGGGGCTCA TGAGCCTCAC GACCAATTTG TACGAAGGCC ACATCGAGAA GGACGCCCGG 1620

GAGTTCCTGG ACAAACAGGT GTGTGGGACC CCAGAGTACA TCGCACCCGA GGTCATCCTG 1680

CGTCAAGGCT ATGGCAAGCC AGTGGACTGG TGGGCCATGG GGATCATCCT CTACGAGTTC 1740

CTGGTGGGCT GTGTGCCCTT CTTCGGAGAT ACGCCAGAAG AACTATTTGG ACAGGTCATC 1800

AGTGATGACA TCCTGTGGCC TGAGGGAGAT GAGGCCCTAC CCACAGAGGC CCAGCTCCTC 1860

ATATCCAGCC TCCTGCAGAC CAACCCTCTA GTCAGGCTTG GGGCAGGCGG TGCTTTTGAG 1920

GTGAAGCAGC ACAGTTTCTT TCGAGACCTG GACTGGACAG GGCTGCTGAG GCAGAAGGCC 1980

GAGTTCATTC CCCACCTAGA GTCGGAAGAT GACACTAGCT ACTTTGACAC CCGCTCAGAC 2040

AGGTATCACC ACGTGAACTC CTATGACGAG GATGACACGA CGGAGGAGGA GCCCGTGGAA 2100

ATCCGCCAGT TCTCTTCCTG CTCTCCGCGC TTCAGCAAGG TGTACAGCGC CTGTATACAT 2160

ATGTACACAT ATAAATAA 2178

Domain Profile

S: 1     feiiklisrGayGavylvrhketrkrfavkkikkqdlilknqvqqvfaerdilalaenpf  60

         f++iklis+GayGavylvrh++tr+rfa+kki+kq+lil+nq+qq+f+erdil++aenpf

Q: 374   FDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPF  433

         99**********************************************************

S: 61    vvslyysletrrnlylvmeyveGGdvksllkniGaldvemarlyiaevvlaleylhryGi  120

         vv +++s+etrr+l++vmeyveGGd+++llkniGal+vemar+y+ae+vlaleylh+yGi

Q: 434   VVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLHNYGI  493

         ************************************************************

S: 121   vhrdlkPdnllitseGhikltdfGlskvglmslttnlyegyidkdarefldkqvcgtPey  180

         vhrdlkPdnllits+GhikltdfGlsk+glmslttnlyeg+i+kdarefldkqvcgtPey

Q: 494   VHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEY  553

         ************************************************************

S: 181   iaPevilrqgygkpvdwwalgiilyeflvgivpffgdtpeelfaqvlsdeivwPekdeal  240

         iaPevilrqgygkpvdwwa+giilyeflvg+vpffgdtpeelf+qv+sd+i wPe+deal

Q: 554   IAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEGDEAL  613

         ************************************************************

S: 241   ssealelisellesnPrerlgtgsaaevkqhefl  274

         ++ea+ lis+ll++nP  rlg+g+a evkqh+f+

Q: 614   PTEAQLLISSLLQTNPLVRLGAGGAFEVKQHSFF  647

         ********************************97

Domain Sequence
(FASTA)

FDTIKLISNG AYGAVYLVRH RDTRQRFAMK KINKQNLILR NQIQQAFVER DILTFAENPF 60

VVGMFCSFET RRHLCMVMEY VEGGDCATLL KNIGALPVEM ARMYFAETVL ALEYLHNYGI 120

VHRDLKPDNL LITSMGHIKL TDFGLSKMGL MSLTTNLYEG HIEKDAREFL DKQVCGTPEY 180

IAPEVILRQG YGKPVDWWAM GIILYEFLVG CVPFFGDTPE ELFGQVISDD ILWPEGDEAL 240

PTEAQLLISS LLQTNPLVRL GAGGAFEVKQ HSFF 274

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR015022	; MA_Ser/Thr_Kinase_dom.
IPR023142	; MAST_pre-PK_dom.
IPR001478	; PDZ.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF08926	; DUF1908; 1.
PF00595	; PDZ; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00228	; PDZ; 1.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS50106	; PDZ; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013