EKS-CAJ-00395

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00395

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	333.2	2.9E-99	544	790	247

Status

Unreviewed

Ensembl Protein

ENSCJAP00000010023

UniProt Accession

F7CQ99;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP3K15

Gene Synonyms/Alias

MAP3K15;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000005459	ENSCJAP00000010023	ENSCJAT00000010589
ENSCJAG00000005459	ENSCJAP00000010009	ENSCJAT00000010574

Organism

Callithrix jacchus

Functional Description

Protein Length

1194

Protein Sequence
(FASTA)

ADVAVVDMSD VCRQPSLFYH LGVRESFDMA NNVILYHDTD ADTALSLKDM VTQKNTASSG 60

NYYFIPYIMT PCADYFCCES NAQRRASEYM QPNWDTILGP LCMPLVDRFI SLLKDIHVTS 120

CVYYKETLLN DIRKAREKYQ GEELAKELAR IKLRMDNTEV LTSDIIINLL LSYRDIQDYD 180

AMVKLVETLE MLPTCDLADQ HNIKFHYAFA LNRRNSTSDR EKALQIMLQV LQSCDHPGPD 240

MFCLCGRIYK DIFLDSDCKD DTSRDSAIEW YRKGFELQSS LYSGINLAVL LIVAGQQFET 300

SLELRKIGVR LNSLLGRKGS LEKMNNYWDV GQFFTVSMLA SDVGKAVQAA ERLFKLKPPV 360

WYLRSLVQNL LLIQRFKKPN IEHSPRQEQL NFWLDIIFEA TNKVTDALRF PVLVIEPTKV 420

YQPSYVSINN EAEERTVSLW HVSPTEMKQM HEWNFAASSI RGISLSKFDE RCCFLYVHDN 480

SDDFQIYFST EEQCSRFFSL VKAMITNTVG STVEPEGETD GDTLEYPVFQ FFEMHSVIKG 540

KNITYGCVYI HINVGERVDC ASRPLYCNKR LYSQPLHEEI ALHKYLKHRN IVQYLGSVSE 600

NGYIKIFMEQ VPGGSLSALL RSKWGPMKEP TIKFYTKQIL EGLKYLHENQ IVHRDIKGDN 660

VLVNTYSGVV KISDFGTSKR LAGVNPCTET FTGTLQYMAP EIIDQGPRGY GAPADIWSLG 720

CTIIEMATSK PPFHELGEPQ AAMFKVGMFK IHPEIPEALS AEARAFILSC FEPDPHKRAT 780

TTELLREGFL RQVNKGKKNR IAFKPSEGPR GVILALPAQG EPMATSSSEH GSISPDSEAH 840

PDVLFERTRA PRPHLGHLLS VPDESSTLED RGLASSPEDR DQGLFLLRKD SERRAILYKI 900

LWEEQNQVAS NLQECVAQSS EELHLSVGHI KQIIGILRDF IRSPEHRVMA TTISKLKVDL 960

DFDSSSISQI HLVLFGFQDA VNHALRNALK TLLFVYFLFE MLPKLILFLR LLLPELRAHF 1020

EPASEAEGVD KDTDEAEEGY LPVAGPGQEP QPHQQHLSLQ LGELRQETNR LLEHLVQKER 1080

EYQNLLRQTL EQKTQELYHL QLKLKSNRIT ESPAALHGQR TDKELIDWLQ LQGADAKTIE 1140

KIIEEGYTLS DILNEITKED LRYLRLRGGL LCRLWSAVSQ YRRAQEASEA KDEA 1194

Nucleotide Sequence
(FASTA)

GCAGATGTTG CTGTGGTAGA CATGAGTGAT GTCTGCAGGC AGCCTTCTCT CTTCTACCAT 60

CTTGGAGTCC GAGAAAGCTT TGACATGGCC AATAACGTGA TCTTGTACCA TGACACCGAT 120

GCCGACACTG CTCTCTCTTT GAAGGACATG GTAACTCAAA AAAACACAGC ATCCAGTGGA 180

AATTATTATT TCATCCCATA CATCATGACA CCGTGCGCTG ATTATTTTTG CTGCGAGAGC 240

AACGCCCAGA GGCGAGCCTC CGAGTACATG CAGCCCAACT GGGACACCAT CCTGGGCCCG 300

CTGTGCATGC CTTTGGTGGA CAGGTTCATT AGCCTCCTTA AGGACATCCA CGTGACCTCA 360

TGTGTTTATT ACAAAGAAAC CTTGTTAAAT GACATCCGGA AAGCCAGAGA GAAATACCAA 420

GGTGAGGAAC TGGCAAAGGA GCTGGCTCGG ATCAAGCTCC GCATGGATAA TACTGAGGTT 480

CTGACCTCAG ACATCATCAT TAACTTACTC CTGTCCTACC GTGATATCCA GGACTATGAT 540

GCGATGGTGA AGCTGGTGGA AACACTGGAG ATGCTGCCTA CGTGTGATTT GGCCGATCAG 600

CATAACATTA AATTCCACTA TGCATTTGCA CTGAATAGGA GAAACAGCAC GAGTGACCGT 660

GAGAAGGCTC TGCAGATCAT GCTCCAGGTT CTGCAGAGCT GTGATCACCC GGGCCCTGAC 720

ATGTTCTGCC TGTGTGGGAG GATCTACAAG GACATCTTCT TGGATTCAGA CTGCAAAGAT 780

GACACCAGCC GAGACAGCGC CATTGAGTGG TATCGCAAAG GGTTTGAACT CCAGTCATCT 840

CTCTATTCGG GAATTAACCT TGCAGTTTTG CTGATAGTTG CTGGACAACA ATTTGAAACT 900

TCCTTGGAAC TAAGGAAAAT AGGTGTCCGG CTGAACAGTT TGTTGGGAAG AAAAGGGAGC 960

TTGGAGAAAA TGAACAATTA CTGGGATGTG GGTCAGTTCT TCACCGTCAG CATGCTGGCC 1020

AGTGATGTCG GGAAAGCTGT CCAGGCAGCA GAGAGGTTGT TCAAACTGAA ACCTCCAGTC 1080

TGGTACCTGC GATCATTAGT TCAGAACTTG TTATTAATTC AGCGCTTCAA GAAACCTAAT 1140

ATCGAACACT CGCCCAGGCA AGAGCAGCTG AACTTCTGGT TAGATATAAT TTTTGAGGCA 1200

ACAAACAAAG TCACTGATGC ACTCAGATTT CCGGTTCTGG TGATAGAGCC AACCAAAGTG 1260

TACCAGCCTT CTTACGTTTC CATAAACAAT GAAGCCGAGG AGAGAACGGT TTCTTTATGG 1320

CATGTCTCAC CCACAGAAAT GAAACAAATG CACGAATGGA ATTTTGCAGC CTCTTCCATA 1380

AGGGGAATCA GCCTATCGAA GTTTGATGAA CGGTGTTGTT TTCTATATGT CCATGATAAT 1440

TCTGATGACT TTCAAATCTA CTTTTCCACC GAAGAGCAGT GTAGTAGATT TTTCTCTTTG 1500

GTCAAAGCAA TGATAACCAA TACAGTGGGC AGTACAGTGG AGCCGGAGGG AGAGACCGAC 1560

GGAGACACCT TGGAGTACCC AGTCTTTCAA TTTTTTGAAA TGCATTCTGT TATTAAAGGA 1620

AAAAATATAA CATATGGGTG TGTATATATA CACATAAACG TAGGTGAAAG AGTAGACTGT 1680

GCATCGCGGC CTTTATATTG TAATAAAAGG TTATATTCTC AGCCTCTGCA CGAGGAGATA 1740

GCCCTGCACA AGTACCTTAA GCACCGCAAT ATCGTTCAGT ACCTGGGCTC TGTTTCAGAG 1800

AACGGCTACA TTAAGATATT TATGGAGCAG GTGCCTGGAG GAAGCCTTTC TGCTCTTTTG 1860

CGATCCAAAT GGGGGCCGAT GAAGGAACCA ACGATCAAGT TTTACACCAA ACAGATCCTG 1920

GAGGGCCTTA AGTATCTCCA TGAAAACCAG ATCGTGCACA GAGACATAAA GGGCGATAAT 1980

GTTCTGGTGA ACACCTACAG CGGAGTGGTG AAAATCTCTG ATTTTGGGAC CTCGAAACGC 2040

CTTGCGGGTG TAAACCCCTG CACAGAGACT TTTACTGGCA CCCTGCAGTA CATGGCACCG 2100

GAGATCATTG ATCAGGGGCC TCGTGGGTAT GGTGCCCCGG CTGATATCTG GTCCCTGGGC 2160

TGCACCATCA TCGAGATGGC CACCAGCAAG CCTCCGTTCC ATGAGCTCGG TGAGCCACAG 2220

GCAGCCATGT TCAAAGTGGG CATGTTTAAG ATCCACCCTG AGATTCCAGA AGCCCTTTCA 2280

GCTGAAGCCC GAGCCTTCAT TTTATCCTGT TTCGAGCCTG ACCCCCACAA ACGTGCCACC 2340

ACCACTGAGC TACTCAGAGA GGGGTTCTTA AGACAGGTGA ACAAGGGCAA GAAAAACCGA 2400

ATTGCCTTCA AGCCCTCAGA GGGTCCGCGG GGTGTCATCC TGGCCCTGCC CGCACAGGGG 2460

GAGCCCATGG CCACCAGCAG CAGCGAGCAT GGCTCCATCT CCCCGGACTC CGAGGCCCAT 2520

CCCGATGTGC TCTTTGAGAG GACCCGGGCG CCCAGGCCTC ACCTTGGCCA CCTTCTCAGT 2580

GTTCCAGATG AGAGCTCAAC CTTGGAAGAC CGGGGCTTGG CCTCGTCCCC AGAGGACAGG 2640

GACCAGGGCC TCTTCCTGCT ACGCAAGGAC AGTGAGCGCC GCGCCATCCT GTACAAAATC 2700

CTCTGGGAGG AGCAGAACCA GGTGGCTTCC AACCTGCAGG AGTGCGTGGC TCAGAGTTCC 2760

GAAGAGCTGC ACCTCTCAGT TGGCCACATC AAGCAAATCA TTGGCATCCT GAGGGACTTC 2820

ATCCGCTCCC CAGAGCACCG GGTGATGGCG ACCACAATAT CAAAGCTCAA GGTGGACCTG 2880

GACTTTGACA GCTCGTCCAT CAGTCAGATT CACCTGGTGC TGTTTGGATT TCAGGATGCC 2940

GTAAATCATG CCCTCAGGAA TGCTTTAAAA ACTTTGCTTT TTGTATATTT CCTTTTTGAA 3000

ATGTTACCAA AGTTGATTCT CTTTCTCCGG TTACTTCTTC CTGAGCTTCG AGCCCACTTT 3060

GAGCCTGCCT CTGAGGCTGA AGGGGTAGAT AAGGACACAG ATGAAGCAGA AGAGGGCTAT 3120

CTCCCAGTGG CCGGACCTGG CCAGGAGCCC CAGCCTCACC AGCAGCACCT GAGCCTCCAG 3180

CTGGGTGAGC TGAGGCAGGA GACCAACAGA CTTTTGGAAC ACCTAGTTCA AAAAGAGAGA 3240

GAGTACCAGA ATCTCCTGCG GCAAACTCTA GAACAGAAAA CTCAAGAATT GTATCACCTT 3300

CAGTTAAAAT TAAAATCAAA TCGTATTACA GAGAGCCCAG CAGCCCTCCA CGGGCAGAGA 3360

ACAGATAAAG AGCTTATAGA CTGGTTGCAG CTGCAAGGAG CTGATGCAAA GACAATCGAA 3420

AAGATTATTG AAGAGGGTTA TACACTGTCT GATATTCTTA ATGAGATCAC TAAGGAAGAT 3480

CTAAGATACC TTCGACTACG GGGTGGTCTC CTCTGCAGGC TCTGGAGCGC GGTTTCCCAG 3540

TACAGAAGGG CTCAGGAGGC CTCAGAAGCC AAAGACGAGG CTTGA 3585

Domain Profile

S: 11    sfgsvyaaldvdtgellavKeveikpekksekkevkalkeEikllkelkHenivkyyGve  70

         ++g vy  ++v ++   a + +    +   ++ ++++l+eEi+l+k lkH+niv+y+G+

Q: 544   TYGCVYIHINVGERVDCASRPLYC--N---KRLYSQPLHEEIALHKYLKHRNIVQYLGSV  598

         79****************999965..2...23489*************************

S: 71    veeeelkiflEyvegGslsslle.kygkleesvikkytkqileglayLHekkivHRDiKg  129

         +e++++kif+E+v+gGsls+ll+ k+g+++e +ik+ytkqilegl+yLHe++ivHRDiKg

Q: 599   SENGYIKIFMEQVPGGSLSALLRsKWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKG  658

         ***********************9************************************

S: 130   aNillds.sgvvklsDFGaskrlaelntkaaelesltGtlaymaPEvikkkekgygrkaD  188

         +N+l+++ sgvvk+sDFG+skrla +n++   +e++tGtl+ymaPE+i+++ +gyg+ aD

Q: 659   DNVLVNTySGVVKISDFGTSKRLAGVNPC---TETFTGTLQYMAPEIIDQGPRGYGAPAD  715

         *****************************...8***************************

S: 189   iWslgcvviemltgkrPfaeldeelaimfkvgakktkPeipeklseegkdflekcleldp  248

         iWslgc++iem+t+k+Pf+el+e++a+mfkvg+ k++Peipe+ls+e+++f+ +c+e dp

Q: 716   IWSLGCTIIEMATSKPPFHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDP  775

         ************************************************************

S: 249   kkrpsaeeLLkhefl  263

         +kr++++eLL++ fl

Q: 776   HKRATTTELLREGFL  790

         ***********9885

Domain Sequence
(FASTA)

TYGCVYIHIN VGERVDCASR PLYCNKRLYS QPLHEEIALH KYLKHRNIVQ YLGSVSENGY 60

IKIFMEQVPG GSLSALLRSK WGPMKEPTIK FYTKQILEGL KYLHENQIVH RDIKGDNVLV 120

NTYSGVVKIS DFGTSKRLAG VNPCTETFTG TLQYMAPEII DQGPRGYGAP ADIWSLGCTI 180

IEMATSKPPF HELGEPQAAM FKVGMFKIHP EIPEALSAEA RAFILSCFEP DPHKRATTTE 240

LLREGFL 247

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR025136	; DUF4071.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR013761	; SAM/pointed.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF13281	; DUF4071; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013