EKS-CAJ-00469

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00469

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/MAPK	416.6	1.0E-124	26	321	296

Status

Unreviewed

Ensembl Protein

ENSCJAP00000010410

UniProt Accession

F7HU18;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPK10

Gene Synonyms/Alias

MAPK10;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000005621	ENSCJAP00000010459	ENSCJAT00000011054
ENSCJAG00000005621	ENSCJAP00000010432	ENSCJAT00000011026
ENSCJAG00000005621	ENSCJAP00000010410	ENSCJAT00000011002
ENSCJAG00000005621	ENSCJAP00000010469	ENSCJAT00000011064
ENSCJAG00000005621	ENSCJAP00000046231	ENSCJAT00000054092

Organism

Callithrix jacchus

Functional Description

Protein Length

426

Protein Sequence
(FASTA)

MSKSKVDNQF YSVEVGDSTF TVLKRYQNLK PIGSGAQGIV CAAYDAVLDR NVAIKKLSRP 60

FQNQTHAKRA YRELVLMKCV NHKNIISLLN VFTPQKTLEE FQDVYLVMEL MDANLCQVIQ 120

MELDHERMSY LLYQMLCGIK HLHSAGIIHR DLKPSNIVVK SDCTLKILDF GLARTAGTSF 180

MMTPYVVTRY YRAPEVILGM GYKENVDIWS VGCIMGEMVR HKILFPGRDY IDQWNKVIEQ 240

LGTPCPEFMK KLQPTVRNYV ENRPKYAGLT FPKLFPDSLF PADSEHNKLK ASQARDLLSK 300

MLVIDPAKRI SVDDALQHPY INVWYDPAEV EAPPPQIYDK QLDEREHTIE EWKELIYKEV 360

MNSEEKTKNG VVKGQPSPSG AAVNSSESLP PSSSVNDISS MSTDQTLASD TDSSLEASAG 420

PLGCCR 426

Nucleotide Sequence
(FASTA)

ATGAGCAAAA GCAAAGTTGA CAACCAGTTC TACAGTGTGG AAGTGGGAGA CTCAACCTTC 60

ACAGTTCTCA AGCGCTACCA GAATCTAAAG CCTATTGGCT CTGGGGCTCA GGGCATAGTT 120

TGTGCCGCGT ATGATGCTGT CCTTGACAGA AATGTGGCCA TTAAGAAGCT CAGCAGACCC 180

TTTCAGAACC AAACACATGC CAAGAGAGCA TACCGGGAGC TGGTCCTCAT GAAGTGTGTG 240

AACCATAAAA ACATCATTAG TTTATTAAAT GTCTTCACAC CCCAGAAAAC GCTGGAGGAG 300

TTCCAAGATG TTTACTTAGT AATGGAACTG ATGGATGCCA ACTTATGTCA AGTGATCCAG 360

ATGGAATTAG ACCACGAGCG AATGTCTTAC CTGCTGTACC AAATGCTGTG TGGCATTAAG 420

CACCTCCACT CTGCTGGAAT TATTCACAGG GATTTAAAAC CAAGTAACAT TGTAGTCAAG 480

TCTGATTGCA CATTGAAAAT CCTGGACTTT GGACTGGCCA GGACAGCAGG CACAAGCTTC 540

ATGATGACTC CGTATGTGGT GACACGTTAT TACAGAGCCC CGGAGGTCAT CCTGGGGATG 600

GGCTACAAGG AGAACGTGGA TATATGGTCT GTGGGATGCA TTATGGGAGA AATGGTTCGC 660

CACAAAATCC TCTTTCCAGG AAGGGACTAT ATTGACCAGT GGAATAAGGT AATTGAACAA 720

CTAGGAACAC CATGTCCAGA ATTCATGAAG AAATTGCAAC CCACAGTAAG AAACTATGTG 780

GAGAATCGGC CCAAGTATGC AGGACTCACC TTCCCCAAGC TCTTCCCAGA TTCCCTCTTC 840

CCAGCGGACT CTGAGCACAA TAAACTCAAA GCCAGCCAAG CCAGGGACTT GTTGTCAAAG 900

ATGCTAGTGA TTGACCCAGC AAAAAGAATA TCAGTGGACG ACGCCTTACA GCATCCCTAC 960

ATCAATGTTT GGTATGACCC AGCTGAAGTG GAGGCGCCTC CACCTCAGAT ATATGACAAG 1020

CAGTTGGATG AAAGAGAACA CACAATTGAA GAATGGAAAG AACTTATCTA CAAGGAAGTA 1080

ATGAACTCGG AAGAAAAGAC TAAAAATGGC GTAGTAAAAG GACAGCCTTC TCCTTCAGGT 1140

GCAGCAGTGA ACAGCAGTGA GAGTCTCCCT CCATCCTCGT CTGTCAATGA CATCTCCTCC 1200

ATGTCCACGG ACCAGACCCT GGCATCTGAC ACTGACAGCA GCCTGGAAGC CTCGGCAGGA 1260

CCCCTGGGTT GTTGCAGGTG A 1281

Domain Profile

S: 1     yeslkplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkelkheNi  60

         y++lkp+g+Ga+g+v++a+d+  +++vaikklsrpfq++t+akr++REl l+k+++h+Ni

Q: 26    YQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNI  85

         899*********************************************************

S: 61    iklldvftpeeeleelkdvYlvtelmetdLkkviksqklsdehiklllyqilrglkylHs  120

         i+ll+vftp+++lee++dvYlv+elm+++L++vi+++ l++e++++llyq+l+g+k+lHs

Q: 86    ISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME-LDHERMSYLLYQMLCGIKHLHS  144

         ************************************9.**********************

S: 121   anviHrDlKPsNllvnedcelkildFGlarsadkekekklteyvatrwYraPeillslke  180

         a++iHrDlKPsN++v++dc+lkildFGlar+a ++ +  +t+yv+tr+YraPe++l  +

Q: 145   AGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFM--MTPYVVTRYYRAPEVILG-MG  201

         **********************************976..*****************9.99

S: 181   ytkavDiWsvGCIlaElltgkplfpgkdeidqlekilevlgtpseeflkkieseearnyi  240

         y+++vDiWsvGCI++E++++k+lfpg+d+idq++k++e+lgtp  ef+kk++  ++rny+

Q: 202   YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQP-TVRNYV  260

         *****************************************************.5*****

S: 241   kslpkkkkkdfeelfpk............aseealdLleklLvldpdkRisveeaLehpY  288

         +++pk++  +f +lfp+            + ++a+dLl+k+Lv+dp kRisv++aL+hpY

Q: 261   ENRPKYAGLTFPKLFPDslfpadsehnklKASQARDLLSKMLVIDPAKRISVDDALQHPY  320

         *****************************99*****************************

S: 289   l  289

Q: 321   I  321

Domain Sequence
(FASTA)

YQNLKPIGSG AQGIVCAAYD AVLDRNVAIK KLSRPFQNQT HAKRAYRELV LMKCVNHKNI 60

ISLLNVFTPQ KTLEEFQDVY LVMELMDANL CQVIQMELDH ERMSYLLYQM LCGIKHLHSA 120

GIIHRDLKPS NIVVKSDCTL KILDFGLART AGTSFMMTPY VVTRYYRAPE VILGMGYKEN 180

VDIWSVGCIM GEMVRHKILF PGRDYIDQWN KVIEQLGTPC PEFMKKLQPT VRNYVENRPK 240

YAGLTFPKLF PDSLFPADSE HNKLKASQAR DLLSKMLVID PAKRISVDDA LQHPYI 296

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004707	; F:MAP kinase activity
GO:0000165	; P:MAPK cascade

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR003527	; MAP_kinase_CS.
IPR008351	; MAPK_JNK.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS01351	; MAPK; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01772

; JNKMAPKINASE.

Created Date

20-Feb-2013