EKS-CAJ-00212

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00212

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	527.7	1.1E-158	5	288	284

Status

Unreviewed

Ensembl Protein

ENSCJAP00000011703

UniProt Accession

F7GM77;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL1

Gene Synonyms/Alias

CDKL1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000006334	ENSCJAP00000011703	ENSCJAT00000012346
ENSCJAG00000006334	ENSCJAP00000011690	ENSCJAT00000012333

Organism

Callithrix jacchus

Functional Description

Protein Length

358

Protein Sequence
(FASTA)

MMEKYEKIGK IGEGSYGVVF KCRNRDTGQI VAIKRFLESE DDPVIKKIAL REIRMLKQLK 60

HPNLVNLLEV FRRKRRLHLV FEYCDHTVLH ELDRYQRGVP EHLVKSITWQ TLKAVNFCHK 120

HNCIHRDVKP ENILITKHSV IKLCDFGFAR LLTGPSDYYT DYVATRWYRS PELLVGDTQY 180

GPPVDVWAIG CVFAELLSGV PLWPGKSDVD QLYLIRKTLG DLIPRHQKVF STNQYFSGVK 240

IPDPEDMEPL ELKFPNISYP ALGLLKGCLR MDPSERLTCE ELLHHPYFEN IREIDDLAKE 300

HDKPTRKTLR KSQKLQCFTE TSKLQYLPQL TGSSILPALD NKKYYCNTKK LNYHFPNI 358

Nucleotide Sequence
(FASTA)

ATGATGGAGA AGTATGAAAA AATTGGGAAA ATTGGAGAAG GATCCTATGG AGTTGTTTTC 60

AAATGTAGAA ACAGGGACAC GGGTCAGATT GTGGCCATCA AGAGGTTTCT GGAATCAGAA 120

GATGACCCTG TCATAAAGAA AATCGCCCTT CGGGAAATCC GCATGCTCAA GCAACTCAAG 180

CATCCCAACC TTGTCAACCT CCTGGAAGTC TTCAGGAGGA AACGGAGGCT TCACCTCGTG 240

TTTGAATATT GTGACCACAC AGTTCTCCAT GAGTTGGACA GATACCAAAG AGGGGTACCA 300

GAACATCTCG TGAAGAGCAT AACTTGGCAG ACCCTGAAAG CCGTAAATTT TTGCCATAAA 360

CACAATTGCA TACATAGAGA CGTGAAGCCG GAAAATATCC TCATCACAAA ACATTCTGTG 420

ATTAAGCTTT GCGACTTTGG ATTTGCTCGG CTTTTGACTG GACCGAGTGA CTATTATACA 480

GACTACGTGG CTACCCGGTG GTACCGCTCC CCTGAGCTGC TGGTCGGGGA CACACAGTAT 540

GGTCCCCCAG TGGATGTTTG GGCAATTGGC TGTGTCTTTG CTGAGCTGCT GTCAGGAGTG 600

CCTCTGTGGC CAGGAAAATC AGATGTGGAT CAGCTCTATC TGATTAGGAA AACCTTGGGA 660

GATCTCATTC CTAGGCACCA GAAAGTGTTT AGCACAAATC AGTACTTCAG TGGAGTGAAA 720

ATTCCAGACC CTGAAGATAT GGAACCACTT GAATTAAAAT TCCCAAACAT CTCTTATCCC 780

GCCCTGGGGC TCTTAAAGGG CTGTCTCCGC ATGGACCCTA GTGAGAGACT GACATGTGAA 840

GAGCTGTTGC ACCACCCGTA TTTTGAAAAC ATCAGAGAAA TAGATGATTT GGCAAAAGAA 900

CATGACAAAC CAACAAGGAA GACCCTAAGA AAGAGCCAAA AGCTCCAGTG CTTTACAGAA 960

ACATCCAAGT TGCAGTACCT ACCCCAGCTA ACTGGCAGCA GCATCCTTCC AGCTTTGGAT 1020

AATAAGAAGT ACTACTGTAA TACCAAGAAA CTGAACTACC ATTTTCCAAA CATTTAA 1077

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         yek+gk+GeGsyGvv+kcrn+dtgqivaik+flesedd+++kkialrei++lkqlkh+nl

Q: 5     YEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLESEDDPVIKKIALREIRMLKQLKHPNL  64

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnllevfrrk++l+lvfey+d+tvl+el+ry++Gv+e+lvk+i++q+lka++fchk+n+i

Q: 65    VNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLKAVNFCHKHNCI  124

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrd+kpenili+k++v+klcdfGfarll++p+d+ytdyvatrwyr+pellvgdt+yG++v

Q: 125   HRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPPV  184

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiGc++aell+G pl+pgksdvdqly+irktlG+liprhqk+fs+n++f+Gvk+p++

Q: 185   DVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQKVFSTNQYFSGVKIPDP  244

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         ed+e+le k+p++++ +l llk+cl++dp+erl+ceell+h+yf

Q: 245   EDMEPLELKFPNISYPALGLLKGCLRMDPSERLTCEELLHHPYF  288

         *******************************************9

Domain Sequence
(FASTA)

YEKIGKIGEG SYGVVFKCRN RDTGQIVAIK RFLESEDDPV IKKIALREIR MLKQLKHPNL 60

VNLLEVFRRK RRLHLVFEYC DHTVLHELDR YQRGVPEHLV KSITWQTLKA VNFCHKHNCI 120

HRDVKPENIL ITKHSVIKLC DFGFARLLTG PSDYYTDYVA TRWYRSPELL VGDTQYGPPV 180

DVWAIGCVFA ELLSGVPLWP GKSDVDQLYL IRKTLGDLIP RHQKVFSTNQ YFSGVKIPDP 240

EDMEPLELKF PNISYPALGL LKGCLRMDPS ERLTCEELLH HPYF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013