EKS-CAJ-00285

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00285

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	452.4	1.4E-135	204	491	288

Status

Unreviewed

Ensembl Protein

ENSCJAP00000012942

UniProt Accession

F6RPX2;

Protein Name

Protein Synonyms/Alias

Gene Name

BMPR1B

Gene Synonyms/Alias

BMPR1B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000006930	ENSCJAP00000051099	ENSCJAT00000054502
ENSCJAG00000006930	ENSCJAP00000012949	ENSCJAT00000013647
ENSCJAG00000006930	ENSCJAP00000012923	ENSCJAT00000013620
ENSCJAG00000006930	ENSCJAP00000046817	ENSCJAT00000056370
ENSCJAG00000006930	ENSCJAP00000012950	ENSCJAT00000013649
ENSCJAG00000006930	ENSCJAP00000012942	ENSCJAT00000013639
ENSCJAG00000006930	ENSCJAP00000012954	ENSCJAT00000013653

Organism

Callithrix jacchus

Functional Description

Protein Length

502

Protein Sequence
(FASTA)

MLLRSAGKIN VGTKKEDGES TAPTPRPKIL RCKCHHHCPE DSVNNICSTD GYCFTMIEED 60

DSGMPVVTSG CLGLEGSDFQ CRDTPIPHQR RSIECCTERN ECNKDLHPTL PPLKNRDFVD 120

GPIHHKALLI SVTVCSLLLV LIILFCYFRY KRQETRPRYS IGLEQDETYI PPGESLRDLI 180

EQSQSSGSGS GLPLLVQRTI AKQIQMVKQI GKGRYGEVWM GKWRGEKVAV KVFFTTEEAS 240

WFRETEIYQT VLMRHENILG FIAADIKGTG SWTQLYLITD YHENGSLYDY LKSTTLDTKS 300

MLKLAYSSVS GLCHLHTEIF STQGKPAIAH RDLKSKNILV KKNGTCCIAD LGLAVKFISD 360

TNEVDIPPNT RVGTKRYMPP EVLDESLNRN HFQSYIMADM YSFGLILWEV ARRCVSGGIV 420

EEYQLPYHDL VPSDPSYEDM REIVCIKKLR PSFPNRWSSD ECLRQMGKLM TECWAHNPAS 480

RLTALRVKKT LAKMSESQDI KL 502

Nucleotide Sequence
(FASTA)

ATGCTTTTGC GAAGTGCAGG AAAAATAAAC GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 60

ACAGCCCCCA CCCCTCGTCC GAAGATCTTG CGTTGTAAAT GCCATCACCA TTGTCCGGAA 120

GACTCGGTTA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT 180

GACTCTGGGA TGCCTGTGGT CACTTCTGGA TGCCTAGGAC TAGAAGGCTC CGATTTTCAG 240

TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGTTGCAC AGAAAGGAAT 300

GAATGTAATA AAGACCTGCA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT 360

GGACCTATAC ACCACAAGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC 420

CTTATCATTT TATTCTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGGTACAGC 480

ATTGGTTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT 540

GAGCAGTCTC AAAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA 600

GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG 660

GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC 720

TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT 780

TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC 840

TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CACTAAATCA 900

ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ACTTACACAC AGAAATCTTT 960

AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAGAA CATTCTGGTG 1020

AAGAAAAATG GAACTTGCTG TATAGCTGAT CTGGGCCTGG CTGTTAAATT TATTAGTGAT 1080

ACAAATGAAG TTGACATACC ACCCAACACT CGAGTTGGCA CCAAACGCTA CATGCCTCCA 1140

GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG 1200

TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG 1260

GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGCG ACCCCTCCTA TGAGGACATG 1320

AGAGAGATTG TGTGCATCAA GAAGTTACGT CCCTCATTCC CAAACCGGTG GAGCAGTGAC 1380

GAGTGTCTCA GGCAGATGGG GAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA 1440

AGGCTGACAG CCCTGCGTGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT 1500

AAACTCTGA 1509

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         ++++++igkGrygeVw++k+rge+vAvK+f+t++easw+rE+eiyqtvl+rhenil+fia

Q: 204   IQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIA  263

         799*********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         ad+k ++s+t+l+l+t+yhe+gsL+dyLk++tld++++l+la+s +sGl+hLH+ei+ t+

Q: 264   ADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDTKSMLKLAYSSVSGLCHLHTEIFSTQ  323

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         g  KpaiaHRDlkskNilvkk++tcciaDlGLa+k+ ++++e+d+  n++vGtkRYm PE

Q: 324   G--KPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPE  381

         *..*********************************************************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         vl+e+ln ++f+++ +aD+Ys+gL+lWEva+Rc + +++veey+lp+++ v+sdPs+e+m

Q: 382   VLDESLNRNHFQSYIMADMYSFGLILWEVARRCVS-GGIVEEYQLPYHDLVPSDPSYEDM  440

         ***********************************.************************

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         +e+v+ kklrP++p++w+++e+l+++ kl++ecW+++p++Rltalrvkk+l

Q: 441   REIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTL  491

         *************************************************97

Domain Sequence
(FASTA)

IQMVKQIGKG RYGEVWMGKW RGEKVAVKVF FTTEEASWFR ETEIYQTVLM RHENILGFIA 60

ADIKGTGSWT QLYLITDYHE NGSLYDYLKS TTLDTKSMLK LAYSSVSGLC HLHTEIFSTQ 120

GKPAIAHRDL KSKNILVKKN GTCCIADLGL AVKFISDTNE VDIPPNTRVG TKRYMPPEVL 180

DESLNRNHFQ SYIMADMYSF GLILWEVARR CVSGGIVEEY QLPYHDLVPS DPSYEDMREI 240

VCIKKLRPSF PNRWSSDECL RQMGKLMTEC WAHNPASRLT ALRVKKTL 288

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0004702	; F:receptor signaling protein serine/threonine kinase activity
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0023014	; P:signal transduction by phosphorylation

KEGG

InterPros

IPR000333	; Activin_II/TGFBeta-II_recpt.
IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR00653

; ACTIVIN2R.

Created Date

20-Feb-2013