EKS-CAJ-00450

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00450

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/DMPK	423.6	6.7E-127	97	360	264

Status

Unreviewed

Ensembl Protein

ENSCJAP00000050551

UniProt Accession

F6YCP8;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100403341

Gene Synonyms/Alias

LOC100403341;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000009005	ENSCJAP00000016696	ENSCJAT00000017650
ENSCJAG00000009005	ENSCJAP00000016633	ENSCJAT00000017584
ENSCJAG00000009005	ENSCJAP00000049894	ENSCJAT00000060459
ENSCJAG00000009005	ENSCJAP00000050551	ENSCJAT00000054202
ENSCJAG00000009005	ENSCJAP00000016689	ENSCJAT00000017643

Organism

Callithrix jacchus

Functional Description

Protein Length

482

Protein Sequence
(FASTA)

MLKFKYGARN PLDAGAAEPI ASRASRLNLF FQGKPPFMTQ QQMSPLSREG ILDALFVLFE 60

ECSQPALMKI KHVSNFVRKY SDTIAELQEL QPSAKDFEVR SLVGCGHFAE VQVVREKATG 120

DIYAMKVMKK KALLAQEQVS FFEEERNILS RSTSPWIPQL QYAFQDKNHL YLVMEYQPGG 180

DLLSLLNRFE DQLDENLIQF YLAELILAVH SVHQMGYVHR DIKPENILID RTGHIKLVDF 240

GSAAKMNSNK MVSARLPVGT PDYMAPEVLT VMNGDGKGTY GLDCDWWSVG VIAYEMIYGR 300

SPFAEGTYAR TFNNIMNFQR FLKFPDDPKV SSDFLDLIQS LLCGQKERLK FEGLCCHPFF 360

SKIDWNNIHN SPPPFVPTLK SDDDTSNFDE PEKNSWVSSS PCQLSPSGFS GEELPFVGFS 420

YSKALGILGR SESVVSGLDS PAKTSSMEKK LLIKSKELQD SQDKCHKMEQ EMTRLHRRVS 480

GG 482

Nucleotide Sequence
(FASTA)

ATGCTGAAGT TCAAATATGG AGCGAGGAAT CCTTTGGATG CTGGTGCTGC TGAACCCATT 60

GCCAGCCGGG CCTCCAGGCT GAATCTGTTC TTCCAGGGGA AACCACCCTT TATGACTCAA 120

CAGCAGATGT CTCCTCTTTC CCGAGAAGGG ATATTAGATG CCCTCTTTGT TCTCTTTGAA 180

GAGTGCAGTC AGCCTGCTCT GATGAAGATT AAGCATGTGA GCAACTTTGT CCGGAAGTAT 240

TCCGACACCA TAGCTGAGTT ACAGGAGCTC CAGCCTTCGG CAAAGGACTT TGAAGTCAGA 300

AGTCTTGTAG GTTGTGGTCA CTTTGCTGAA GTGCAGGTGG TAAGAGAGAA AGCAACTGGG 360

GACATCTATG CCATGAAAGT GATGAAGAAG AAGGCCTTAT TGGCCCAGGA GCAGGTTTCG 420

TTTTTTGAGG AAGAACGAAA CATATTATCT CGAAGCACAA GCCCTTGGAT CCCCCAATTA 480

CAGTATGCCT TTCAGGACAA AAATCACTTG TATCTGGTCA TGGAATATCA GCCTGGAGGG 540

GACTTGCTGT CACTTTTGAA TAGATTTGAG GACCAATTAG ATGAAAATCT GATTCAGTTT 600

TACCTGGCTG AACTGATTTT GGCTGTTCAC AGCGTTCATC AGATGGGATA TGTGCATCGA 660

GACATCAAGC CCGAGAACAT TCTCATTGAC CGCACAGGAC ACATCAAGCT GGTGGATTTT 720

GGATCAGCTG CGAAAATGAA TTCAAACAAG ATGGTGAGTG CCAGACTCCC AGTTGGGACC 780

CCAGATTACA TGGCTCCTGA AGTGCTGACT GTGATGAATG GGGATGGAAA AGGCACCTAC 840

GGCCTTGACT GTGACTGGTG GTCGGTGGGC GTGATTGCCT ATGAGATGAT TTATGGGAGA 900

TCCCCCTTTG CAGAGGGAAC CTACGCCAGA ACCTTCAATA ACATCATGAA TTTCCAGCGG 960

TTTTTGAAGT TTCCAGATGA CCCCAAAGTG AGCAGTGACT TTCTTGATCT GATTCAAAGT 1020

TTGTTGTGTG GCCAGAAAGA GAGGCTGAAG TTTGAAGGCC TTTGCTGCCA TCCTTTCTTC 1080

TCGAAAATTG ACTGGAATAA CATTCATAAC TCTCCTCCCC CCTTCGTTCC CACCCTCAAG 1140

TCTGACGATG ACACCTCCAA TTTTGATGAA CCAGAGAAGA ATTCGTGGGT TTCATCCTCT 1200

CCGTGCCAGC TGAGCCCCTC AGGTTTCTCG GGTGAAGAAC TGCCGTTTGT GGGGTTTTCC 1260

TACAGCAAGG CACTGGGGAT TCTTGGTAGA TCTGAGTCTG TTGTGTCGGG TCTGGACTCC 1320

CCTGCCAAGA CTAGCTCCAT GGAAAAGAAA CTTCTCATCA AAAGCAAAGA GCTACAAGAC 1380

TCTCAGGACA AGTGTCACAA GATGGAGCAG GAAATGACCC GGTTACATCG GAGAGTGTCA 1440

GGTGGCTGA 1449

Domain Profile

S: 1     feilkviGrGafgevavvrekatekvyamkilkklellkraesaffreerdvlvkadsew  60

         fe+++++G+G+f+ev+vvrekat+++yamk++kk++ll++++++ff+eer++l++++s+w

Q: 97    FEVRSLVGCGHFAEVQVVREKATGDIYAMKVMKKKALLAQEQVSFFEEERNILSRSTSPW  156

         89**********************************************************

S: 61    ivqlqyafqdekylylvmeylvGGdlltllskyedklpeelarfylaelvlaldsvhelg  120

         i qlqyafqd+++lylvmey++GGdll+ll+++ed+l+e+l++fylael+la++svh++g

Q: 157   IPQLQYAFQDKNHLYLVMEYQPGGDLLSLLNRFEDQLDENLIQFYLAELILAVHSVHQMG  216

         ************************************************************

S: 121   yvhrdikpdnilldksGhikladfGsclklnedgtvkssvavGtpdyispevlkalee.g  179

         yvhrdikp+nil+d++Ghikl+dfGs++k+n++++v+++ +vGtpdy++pevl++++  g

Q: 217   YVHRDIKPENILIDRTGHIKLVDFGSAAKMNSNKMVSARLPVGTPDYMAPEVLTVMNGdG  276

         ********************************************************977*

S: 180   kgeygkecdwwslGvilyellvgetpfyaeslvetyskilnhkeslkfpedekvseeakd  239

         kg+yg +cdwws+Gvi+ye+++g++pf + + ++t+++i+n++++lkfp+d kvs+++ d

Q: 277   KGTYGLDCDWWSVGVIAYEMIYGRSPFAEGTYARTFNNIMNFQRFLKFPDDPKVSSDFLD  336

         ************************************************************

S: 240   likklltsreerlgregiedlkkhpff  266

         li++ll+ ++erl++eg+   ++hpff

Q: 337   LIQSLLCGQKERLKFEGL---CCHPFF  360

         *****************9...*****9

Domain Sequence
(FASTA)

FEVRSLVGCG HFAEVQVVRE KATGDIYAMK VMKKKALLAQ EQVSFFEEER NILSRSTSPW 60

IPQLQYAFQD KNHLYLVMEY QPGGDLLSLL NRFEDQLDEN LIQFYLAELI LAVHSVHQMG 120

YVHRDIKPEN ILIDRTGHIK LVDFGSAAKM NSNKMVSARL PVGTPDYMAP EVLTVMNGDG 180

KGTYGLDCDW WSVGVIAYEM IYGRSPFAEG TYARTFNNIM NFQRFLKFPD DPKVSSDFLD 240

LIQSLLCGQK ERLKFEGLCC HPFF 264

Keyword

ATP-binding; Complete proteome; Kinase; Metal-binding; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase; Zinc; Zinc-finger.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005622	; C:intracellular
GO:0005524	; F:ATP binding
GO:0046872	; F:metal ion binding
GO:0005543	; F:phospholipid binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0005083	; F:small GTPase regulator activity
GO:0035556	; P:intracellular signal transduction

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR001180	; Citron.
IPR017405	; Citron_Rho-interacting_kinase.
IPR011009	; Kinase-like_dom.
IPR011993	; PH_like_dom.
IPR017892	; Pkinase_C.
IPR001849	; Pleckstrin_homology.
IPR002219	; Prot_Kinase_C-like_PE/DAG-bd.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00780	; CNH; 1.
PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00109	; C1; 1.
SM00036	; CNH; 1.
SM00233	; PH; 1.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS50219	; CNH; 1.
PS50003	; PH_DOMAIN; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013