EKS-CAJ-00199

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00199

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/LISK	422.2	1.6E-126	36	290	255

Status

Unreviewed

Ensembl Protein

ENSCJAP00000017385

UniProt Accession

F7I2Z2;

Protein Name

Protein Synonyms/Alias

Gene Name

TESK1

Gene Synonyms/Alias

TESK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000009457	ENSCJAP00000045549	ENSCJAT00000063221
ENSCJAG00000009457	ENSCJAP00000017403	ENSCJAT00000018405
ENSCJAG00000009457	ENSCJAP00000017385	ENSCJAT00000018387

Organism

Callithrix jacchus

Functional Description

Protein Length

605

Protein Sequence
(FASTA)

MAGERPPLRG PGPGPGDSSY RALRSAVSSL ARVDDFHCAE KIGAGFFSEV YKVRHRQSGQ 60

VMVLKMNKLP SNRGNTLREV QLMNRLRHPN ILRFMGVCVH QGQLHALTEY MNGGTLEQLL 120

SSPEPLSWPV RLHLALDIAR GLRYLHSKGV FHRDLTSKNC LVRREDGGFT AVVGDFGLAE 180

KIPVYREGAR KEPLAVVGSP YWMAPEVLRG ELYDEKADVF AFGIVLCELI ARVPADPDYL 240

PRTEDFGLDV PAFRTLVGDD CPLPFLLLAI HCCSMEPSTR APFTEITQHL EWILEQLPEP 300

APLTRTRLTH NQGFVPRGGP SATLPRPDPR LSRSRSDLFL PPSPESPPNW GDNLTRVNPF 360

SLREDLRGGK IKLLDTPSKP VLPLVPPSPL PSTQLPLVTT PETLVQPGTP ARRCRSLPSS 420

PELPRRMETA LPGPGPPPVG PSAEEKMECE GSSPEPEPPG PAPQLPLAVA TDNFISTCSS 480

ASQPWSPRSG PALNNNPPAV VVHSPQGWAG EPWNRAQHSL PRAAALERTE ASPPPSAPRE 540

PDEGLPCPGC CLGPFSFGFL SMCPRPTPAV ARYRNLNCEA GSLLCHRGHH AKPPTPSLQL 600

PGARS 605

Nucleotide Sequence
(FASTA)

ATGGCCGGGG AACGGCCCCC ACTGCGGGGC CCTGGGCCCG GGCCTGGAGA CTCCTCCTAC 60

CGGGCTCTCC GCAGCGCCGT GTCTAGCCTG GCGCGTGTGG ACGATTTCCA CTGCGCGGAG 120

AAGATCGGGG CCGGCTTCTT CTCTGAGGTC TACAAGGTTC GGCATCGACA GTCAGGGCAA 180

GTCATGGTGC TGAAGATGAA CAAGCTCCCC AGTAACCGGG GCAACACACT ACGGGAAGTG 240

CAGTTGATGA ACCGACTCCG GCACCCCAAC ATCCTAAGGT TCATGGGGGT CTGTGTGCAC 300

CAGGGACAGC TGCACGCTCT TACAGAGTAT ATGAATGGGG GGACGTTGGA ACAGCTGCTC 360

AGCTCCCCTG AACCCCTATC CTGGCCGGTA AGGCTCCACC TGGCCCTGGA CATTGCCCGA 420

GGCCTGCGGT ACCTGCACTC CAAAGGTGTA TTTCACCGCG ACCTCACATC CAAGAACTGT 480

CTAGTCCGAC GGGAAGATGG AGGCTTCACA GCTGTCGTGG GTGACTTCGG GCTGGCTGAA 540

AAGATTCCTG TGTATAGGGA AGGGGCAAGG AAGGAGCCAT TGGCCGTGGT GGGCTCCCCA 600

TACTGGATGG CTCCAGAGGT ATTGCGGGGT GAGCTGTATG ATGAGAAGGC TGATGTCTTT 660

GCCTTCGGGA TTGTCCTCTG TGAGCTCATT GCCCGAGTAC CTGCGGACCC TGACTACCTA 720

CCACGCACTG AGGACTTTGG CTTGGATGTG CCTGCTTTCC GAACTCTGGT GGGGGATGAC 780

TGCCCACTGC CTTTCCTGCT CCTGGCCATC CACTGCTGCA GCATGGAACC CAGCACCCGC 840

GCCCCCTTCA CTGAAATTAC CCAGCACCTA GAATGGATCC TGGAGCAGCT GCCTGAGCCA 900

GCCCCACTCA CCAGGACTCG CCTGACACAT AATCAGGGCT TTGTTCCAAG AGGGGGTCCC 960

TCTGCTACGC TTCCCAGGCC AGACCCCCGG CTTTCCCGAA GCCGGTCAGA CCTCTTCCTG 1020

CCCCCATCAC CAGAATCACC CCCCAACTGG GGGGACAATC TGACTCGAGT CAACCCCTTC 1080

TCACTACGGG AAGACCTCAG GGGTGGCAAG ATCAAGCTCT TGGACACACC CAGCAAGCCA 1140

GTCCTGCCTC TTGTGCCACC ATCGCCACTG CCCTCCACTC AGCTGCCCTT GGTGACCACT 1200

CCGGAGACTC TGGTCCAGCC TGGAACACCT GCCCGCCGCT GCCGCTCGCT ACCCTCATCC 1260

CCTGAGCTCC CCCGCCGTAT GGAGACAGCA CTGCCAGGTC CTGGCCCTCC CCCTGTGGGC 1320

CCCTCAGCTG AAGAGAAGAT GGAGTGTGAG GGCAGCAGCC CAGAGCCGGA ACCTCCAGGT 1380

CCAGCACCCC AGCTGCCTCT GGCTGTGGCC ACAGACAACT TCATCAGCAC CTGTTCCTCG 1440

GCCTCCCAAC CCTGGTCCCC TAGATCAGGG CCCGCCCTCA ATAACAACCC CCCAGCTGTG 1500

GTGGTGCACT CCCCACAAGG CTGGGCTGGG GAGCCCTGGA ACCGGGCCCA GCATAGCCTG 1560

CCCCGGGCAG CAGCCCTGGA GCGGACAGAA GCCTCGCCAC CCCCTTCAGC TCCCCGAGAG 1620

CCTGATGAGG GGCTGCCCTG TCCTGGCTGC TGCCTCGGCC CCTTCAGCTT TGGCTTCTTG 1680

TCCATGTGCC CCCGCCCCAC ACCAGCTGTT GCCCGCTACC GCAACCTGAA CTGTGAGGCG 1740

GGCAGTCTCC TCTGCCACCG AGGGCACCAC GCCAAGCCAC CCACACCCAG CCTGCAGCTG 1800

CCTGGGGCAC GCTCTTAG 1818

Domain Profile

S: 1     livgeklGkGffsevfkvthrasGevmvlkeliradeenrknllkevkllrklehpnvlk  60

         ++++ek+G+Gffsev+kv+hr+sG+vmvlk  ++++ +nr n+l+ev+l+++l+hpn+l+

Q: 36    FHCAEKIGAGFFSEVYKVRHRQSGQVMVLK--MNKLPSNRGNTLREVQLMNRLRHPNILR  93

         689***************************..****************************

S: 61    fiGvlvkdkklhllteyiegGtlkellkskeslpwtqrvrlakdiasGlsylhskgiihr  120

         f+Gv+v++++lh+ltey++gGtl++ll+s+e+l+w++r++la dia+Gl+ylhskg++hr

Q: 94    FMGVCVHQGQLHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIARGLRYLHSKGVFHR  153

         ************************************************************

S: 121   dlnsknclvre...dksvvvadfGlarlvveerkkseklrslkkkdrkkrltvvGsPywm  177

         dl+sknclvr+   ++++vv+dfGla          ek++++++++rk+ l+vvGsPywm

Q: 154   DLTSKNCLVRRedgGFTAVVGDFGLA----------EKIPVYREGARKEPLAVVGSPYWM  203

         ***********99889**********..........9***********************

S: 178   aPevlkgksydekvdvfsfGivlceiiarveadPdylPrtedfgldvkafreklvaedcP  237

         aPevl+g+ ydek+dvf+fGivlce+iarv adPdylPrtedfgldv afr+ lv++dcP

Q: 204   APEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRT-LVGDDCP  262

         ****************************************************.*******

S: 238   eaflklavvccdldpesrpsfeelekkl  265

          +fl la++cc+++p++r++f+e++++l

Q: 263   LPFLLLAIHCCSMEPSTRAPFTEITQHL  290

         *************************987

Domain Sequence
(FASTA)

FHCAEKIGAG FFSEVYKVRH RQSGQVMVLK MNKLPSNRGN TLREVQLMNR LRHPNILRFM 60

GVCVHQGQLH ALTEYMNGGT LEQLLSSPEP LSWPVRLHLA LDIARGLRYL HSKGVFHRDL 120

TSKNCLVRRE DGGFTAVVGD FGLAEKIPVY REGARKEPLA VVGSPYWMAP EVLRGELYDE 180

KADVFAFGIV LCELIARVPA DPDYLPRTED FGLDVPAFRT LVGDDCPLPF LLLAIHCCSM 240

EPSTRAPFTE ITQHL 255

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0046872	; F:metal ion binding
GO:0004713	; F:protein tyrosine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR015782	; Testis-specific_kinase_1.
IPR008266	; Tyr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.

Prints

PR00109

; TYRKINASE.

Created Date

20-Feb-2013