EKS-CAJ-00289

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00289

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	408.1	4.3E-122	172	459	288

Status

Unreviewed

Ensembl Protein

ENSCJAP00000018582

UniProt Accession

F7CZG7;

Protein Name

Protein Synonyms/Alias

Gene Name

ACVR2B

Gene Synonyms/Alias

ACVR2B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000010067	ENSCJAP00000018577	ENSCJAT00000019626
ENSCJAG00000010067	ENSCJAP00000018582	ENSCJAT00000019631
ENSCJAG00000010067	ENSCJAP00000018562	ENSCJAT00000019611

Organism

Callithrix jacchus

Functional Description

Protein Length

475

Protein Sequence
(FASTA)

SGRGEAETRE CIYYNANWEL ERTNQSGLEH CEGEQDKRLH CYASWRNSSG TIELVKKGCW 60

LDDFNCYDRQ ECVATEENPQ VYFCCCEGNF CNERFTHLPE AGGPEVTYEP PSTAPTLLTV 120

LAYSLLPVGG LSLIVLLAFW IYRHRKPPYG HVDIHEDPGP PPPSPLVGLK PLQLLEIKAR 180

GRFGCVWKAQ LMNDFVAVKI FPLQDKKSWQ SEREIFSTPG MKHENLLQFI AAEKRGSNLE 240

VELWLITAFH DKGSLTDYLK GNIVTWNELC HVAETMSRGL SYLHEDVPWC RGEGHKPSIA 300

HRDFKSKNVL LKSDLTAVLA DFGLAVRFEP GKPPGDTHGQ VGTRRYMAPE VLEGAINFQR 360

DAFLRIDMYA MGLVLWELVS RCKAADGPVD EYMLPFEEEI GQHPSLEELQ EVVVHKKMRP 420

TIKDHWLKHP GLAQLCVTIE ECWDHDAEAR LSAGCVEERV SLIRRSVNGT SSFPW 475

Nucleotide Sequence
(FASTA)

TCTGGGCGTG GGGAGGCTGA GACACGGGAG TGCATCTACT ACAACGCCAA CTGGGAGCTG 60

GAGCGCACCA ACCAGAGCGG CCTGGAGCAC TGCGAGGGCG AGCAGGACAA GCGGCTGCAC 120

TGCTACGCCT CGTGGCGCAA CAGCTCTGGC ACCATCGAGC TCGTGAAGAA GGGCTGCTGG 180

CTGGACGACT TCAACTGCTA CGATAGGCAG GAGTGTGTGG CCACTGAGGA GAACCCCCAG 240

GTGTACTTCT GCTGCTGTGA AGGCAACTTC TGCAACGAGC GCTTCACTCA TTTGCCAGAG 300

GCTGGGGGCC CAGAAGTCAC GTACGAGCCA CCCTCGACAG CCCCCACCTT GCTAACGGTG 360

CTGGCCTACT CACTGCTGCC CGTCGGGGGC CTTTCCCTCA TTGTCCTACT GGCTTTCTGG 420

ATATACCGGC ATCGCAAGCC CCCCTACGGC CACGTAGACA TCCATGAGGA CCCTGGGCCT 480

CCACCCCCAT CCCCTCTGGT GGGCCTGAAG CCACTGCAGC TGCTGGAGAT CAAGGCTCGG 540

GGGCGCTTTG GCTGTGTCTG GAAGGCCCAG CTCATGAACG ACTTTGTAGC TGTCAAGATC 600

TTTCCGCTCC AGGACAAGAA GTCGTGGCAG AGTGAACGGG AGATCTTCAG CACACCTGGC 660

ATGAAGCACG AGAACCTGCT ACAGTTCATT GCTGCGGAGA AGCGAGGCTC CAACCTTGAA 720

GTAGAGCTGT GGCTCATCAC GGCCTTCCAT GACAAGGGCT CCCTCACAGA TTACCTCAAG 780

GGGAACATCG TCACATGGAA CGAACTGTGT CACGTAGCAG AGACAATGTC ACGAGGCCTG 840

TCATACCTGC ATGAGGACGT GCCCTGGTGC CGTGGTGAGG GCCACAAGCC GTCTATTGCC 900

CACAGGGACT TTAAAAGCAA GAATGTATTG CTGAAGAGCG ACCTCACAGC CGTGCTGGCT 960

GACTTTGGCC TGGCTGTTCG ATTTGAGCCA GGGAAACCTC CAGGGGATAC CCACGGACAG 1020

GTAGGTACGA GACGGTACAT GGCTCCTGAG GTGCTCGAGG GAGCCATCAA CTTCCAGAGA 1080

GATGCCTTCC TGCGCATTGA CATGTATGCC ATGGGGCTGG TGCTGTGGGA GCTGGTGTCT 1140

CGCTGCAAGG CTGCAGATGG ACCTGTGGAT GAGTACATGC TGCCCTTTGA GGAAGAAATT 1200

GGCCAGCACC CTTCATTGGA GGAGCTGCAG GAGGTGGTGG TGCACAAGAA GATGAGACCC 1260

ACCATTAAGG ATCACTGGTT GAAACATCCG GGCCTGGCCC AGCTCTGTGT GACCATCGAG 1320

GAATGCTGGG ACCATGATGC AGAGGCGCGC TTGTCCGCGG GCTGTGTGGA GGAGCGGGTG 1380

TCCCTGATTC GGAGGTCGGT CAACGGCACT AGCTCGTTTC CCTGGTGA 1428

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         l+lle+ ++Gr+g+Vwka+l+++ vAvKif+ +d++sw++E+ei++t+ ++hen+lqfia

Q: 172   LQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKKSWQSEREIFSTPGMKHENLLQFIA  231

         6899********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         a+k+ +++++el+l+t++h+kgsL+dyLk ++++++el+++a+++++Gl++LHe++++++

Q: 232   AEKRGSNLEVELWLITAFHDKGSLTDYLKGNIVTWNELCHVAETMSRGLSYLHEDVPWCR  291

         ************************************************************

S: 121   g.kkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaP  179

         g  +Kp+iaHRD+kskN+l+k+dlt+++aD+GLa+++e  k   d  ++ qvGt+RYmaP

Q: 292   GeGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGD--THGQVGTRRYMAP  349

         *99***************************************888..79***********

S: 180   EvleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPslee  239

         Evle+a+n+++ +af r+D+Y++gLvlWE++sRc+++d+ v+ey+lpfee++g++Pslee

Q: 350   EVLEGAINFQR-DAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEE  408

         **********9.9***********************************************

S: 240   mkevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkr  290

         ++evvv+kk+rP+i+++w k++ l++l+ ++eecWd+d+eaRl+a +v++r

Q: 409   LQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEER  459

         ************************************************998

Domain Sequence
(FASTA)

LQLLEIKARG RFGCVWKAQL MNDFVAVKIF PLQDKKSWQS EREIFSTPGM KHENLLQFIA 60

AEKRGSNLEV ELWLITAFHD KGSLTDYLKG NIVTWNELCH VAETMSRGLS YLHEDVPWCR 120

GEGHKPSIAH RDFKSKNVLL KSDLTAVLAD FGLAVRFEPG KPPGDTHGQV GTRRYMAPEV 180

LEGAINFQRD AFLRIDMYAM GLVLWELVSR CKAADGPVDE YMLPFEEEIG QHPSLEELQE 240

VVVHKKMRPT IKDHWLKHPG LAQLCVTIEE CWDHDAEARL SAGCVEER 288

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0017002	; F:activin-activated receptor activity
GO:0005524	; F:ATP binding
GO:0004702	; F:receptor signaling protein serine/threonine kinase activity
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0023014	; P:signal transduction by phosphorylation

KEGG

InterPros

IPR000333	; Activin_II/TGFBeta-II_recpt.
IPR015768	; Activin_II_recpt.
IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR00653

; ACTIVIN2R.

Created Date

20-Feb-2013