EKS-CAJ-00062

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00062

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	369.1	3.0E-110	39	323	285

Status

Unreviewed

Ensembl Protein

ENSCJAP00000019813

UniProt Accession

F7C8F5;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK10

Gene Synonyms/Alias

CDK10;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000010752	ENSCJAP00000030045	ENSCJAT00000031753
ENSCJAG00000010752	ENSCJAP00000019835	ENSCJAT00000020964
ENSCJAG00000010752	ENSCJAP00000019839	ENSCJAT00000020966
ENSCJAG00000010752	ENSCJAP00000019813	ENSCJAT00000020939

Organism

Callithrix jacchus

Functional Description

Protein Length

360

Protein Sequence
(FASTA)

MAEPDSESEH IRLKCIRKEG FFTVPPEHRL GRCRSVKEFE KLNRIGEGTY GIVYRARDTQ 60

TDEIVALKKV RMDKEKDGIP ISSLREITLL LRLRHPNIVE LKEVVVGNHL ESIFLVMGYC 120

EQDLASLLEN MPTPFSEAQV KCIVLQVLRG LQYLHRNFII HRDLKVSNLL MTDKGCVKTA 180

DFGLARAYGV PVKPMTPKVV TLWYRAPELL LGTTTQTTSI DMWAVGCILA ELLAHKPLLP 240

GTSEIHQIDL IVQLLGTPSE TIWPGFSKLP LVGQYSLRKQ PYNNLKHKFP WLSEAGLRLL 300

HFLFMYDPKK RATAGDCLES SYFKEKPLPC EPELMPTFPH HRNKRAAPAT SEGQSKRCKP 360

Nucleotide Sequence
(FASTA)

ATGGCGGAGC CTGACTCGGA GTCGGAGCAC ATCCGTCTGA AGTGCATTCG TAAGGAGGGC 60

TTCTTCACGG TGCCTCCAGA ACACAGGCTG GGGCGATGCC GGAGTGTGAA GGAGTTCGAG 120

AAGCTGAACC GGATTGGAGA GGGCACTTAC GGCATCGTGT ATCGGGCGCG GGACACCCAG 180

ACAGATGAGA TTGTTGCGCT GAAGAAGGTG CGGATGGACA AGGAGAAGGA TGGCATCCCC 240

ATCAGCAGCC TGCGGGAGAT CACGCTGCTG CTCCGCCTAC GCCACCCGAA TATCGTGGAG 300

CTGAAGGAGG TGGTTGTCGG GAACCACCTG GAGAGTATCT TCCTGGTGAT GGGTTACTGT 360

GAGCAGGACC TGGCCAGCCT CCTGGAGAAT ATGCCAACAC CCTTCTCGGA GGCCCAGGTC 420

AAGTGCATCG TGCTGCAGGT GCTCCGGGGC CTCCAGTACC TGCACAGGAA CTTCATCATC 480

CACAGGGACC TGAAGGTCTC CAACTTGCTC ATGACTGACA AGGGCTGCGT GAAGACAGCG 540

GATTTTGGCC TGGCCCGGGC CTACGGTGTC CCAGTAAAGC CGATGACCCC CAAGGTGGTC 600

ACTCTCTGGT ACCGAGCCCC CGAGCTGCTG CTGGGAACCA CCACACAGAC CACCAGCATC 660

GACATGTGGG CCGTGGGCTG CATCCTGGCC GAGCTGCTGG CCCACAAGCC CCTTCTCCCC 720

GGCACCTCCG AGATCCACCA GATTGACTTG ATCGTGCAGC TGCTGGGGAC GCCGAGTGAG 780

ACCATCTGGC CGGGCTTTTC CAAGCTGCCG CTGGTTGGTC AGTATAGCCT TCGGAAGCAG 840

CCGTACAACA ACCTAAAGCA CAAGTTCCCA TGGCTGTCGG AGGCTGGGCT GCGCCTGCTC 900

CACTTCCTGT TCATGTACGA CCCTAAGAAA AGGGCGACCG CTGGGGACTG CCTGGAGAGC 960

TCCTACTTCA AGGAGAAGCC CCTGCCCTGT GAGCCGGAGC TCATGCCCAC CTTTCCTCAC 1020

CACCGCAACA AGCGGGCCGC CCCGGCCACC TCCGAGGGCC AGAGCAAGCG CTGCAAGCCC 1080

TGA 1083

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         +ekl++igeGtyg vy+a+d++t+e+vAlKk+r++kek+g+pi++lrEi+ll +l+h+ni

Q: 39    FEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNI  98

         89**********************************************************

S: 61    vkLlevvakdk.kklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsn  119

         v+L+evv+ ++ ++++Lv+ ++eqdL++ll+++++  +s+++vk ++lq+l+gl+ylH+n

Q: 99    VELKEVVVGNHlESIFLVMGYCEQDLASLLENMPT-PFSEAQVKCIVLQVLRGLQYLHRN  157

         ********5555***********************.************************

S: 120   kilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYs  179

          i+HRDlK +NlL++++g++k aDfGlara+++p+k +t++vvTlwYraPelLlg+++ +

Q: 158   FIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQT  217

         ************************************************************

S: 180   tavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksf  238

         t++D+W+vgcilaell++kpl++g+sei+q++ i++llgtpse++wp++sklp +  +s+

Q: 218   TSIDMWAVGCILAELLAHKPLLPGTSEIHQIDLIVQLLGTPSETIWPGFSKLPLVGqYSL  277

         *******************************************************988**

S: 239   pkkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         +k+++++lk+k++ l+e++l+ll+ l+++dpkkR +a ++l+++yf

Q: 278   RKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYF  323

         *********************************************8

Domain Sequence
(FASTA)

FEKLNRIGEG TYGIVYRARD TQTDEIVALK KVRMDKEKDG IPISSLREIT LLLRLRHPNI 60

VELKEVVVGN HLESIFLVMG YCEQDLASLL ENMPTPFSEA QVKCIVLQVL RGLQYLHRNF 120

IIHRDLKVSN LLMTDKGCVK TADFGLARAY GVPVKPMTPK VVTLWYRAPE LLLGTTTQTT 180

SIDMWAVGCI LAELLAHKPL LPGTSEIHQI DLIVQLLGTP SETIWPGFSK LPLVGQYSLR 240

KQPYNNLKHK FPWLSEAGLR LLHFLFMYDP KKRATAGDCL ESSYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013