EKS-CAJ-00068

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00068

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	346.6	2.1E-103	172	448	277

Status

Unreviewed

Ensembl Protein

ENSCJAP00000022511

UniProt Accession

F7IFN0;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK18

Gene Synonyms/Alias

CDK18;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000010878	ENSCJAP00000020088	ENSCJAT00000021226
ENSCJAG00000010878	ENSCJAP00000022511	ENSCJAT00000023812

Organism

Callithrix jacchus

Functional Description

Protein Length

497

Protein Sequence
(FASTA)

INMNKMKNFK RHFSMSVTRT ETIKESLAEF TEQFNQLQNR RNEDLQLGPL GRDSPQECSP 60

FSPADSGEEP GQLSPGMRFQ QRQNQRRFSM EVSASGALTW EGGMGRSVHR RAAGMRFMWD 120

VSKRLSLPMD IRLPQEFLQK LQMESPDLPK PLSRMSRRAS LSDIGFGKLE TYVKLDKLGE 180

GTYATVFKGR SKLTENLVAL KEIRLEHEEG APCTAIREVS LLKNLEAPPD LIHTDRSLTL 240

VLSTWDSDLK QYLDHCGNLM SMHNVKIFMF QLLRGLAYCH HRKILHRDLK PQNLLINERG 300

ELKLADFGLA RAKSVPTKTY SNEVVTLWYR PPDVLLGSTE YSTPIDMWGV GCIHYEMATG 360

RPLFPGSTVK EELHLIFRLL GTPTEETWPG VTAFSEFRTY SFPRYLPQPL INHAPRLDTD 420

GIHLLSSLLL YESKSRMSAE AALSHPYFRP LGERVHQLED TASIFSLKEI QLQKDPGYRS 480

LAFQHPGRGL CPPGPFL 497

Nucleotide Sequence
(FASTA)

ATAAACATGA ACAAGATGAA GAACTTTAAG CGCCATTTCT CCATGTCAGT GACCCGCACC 60

GAGACCATCA AAGAATCCTT GGCTGAATTC ACGGAGCAAT TCAACCAGCT CCAAAACCGG 120

AGGAATGAGG ACCTGCAGCT CGGTCCTCTT GGCAGAGACT CCCCGCAGGA GTGCAGCCCC 180

TTCTCCCCAG CAGACAGCGG GGAGGAGCCA GGGCAGCTGT CCCCTGGCAT GCGGTTCCAG 240

CAGCGGCAGA ACCAGCGCCG CTTCTCCATG GAGGTGAGTG CTTCCGGAGC TCTGACCTGG 300

GAAGGTGGCA TGGGCAGGAG TGTCCATAGG AGGGCAGCTG GTATGAGATT TATGTGGGAT 360

GTCAGCAAGA GGCTCTCTCT GCCCATGGAT ATCCGCCTGC CCCAGGAGTT CTTACAGAAG 420

CTACAGATGG AAAGCCCAGA TCTGCCCAAA CCGCTCAGCC GCATGTCCCG CCGGGCTTCT 480

CTGTCAGACA TTGGCTTTGG GAAACTGGAA ACCTACGTGA AACTGGACAA ACTGGGAGAG 540

GGCACCTATG CCACAGTCTT CAAAGGCCGC AGCAAGCTGA CGGAGAACCT CGTGGCCCTG 600

AAGGAGATCC GGCTGGAGCA TGAGGAGGGA GCACCCTGCA CTGCCATTCG AGAGGTGTCT 660

TTGCTGAAGA ACCTTGAAGC ACCGCCAGAC CTCATTCACA CAGATCGGTC CCTCACCCTG 720

GTGTTGAGTA CCTGGGACAG TGACCTGAAG CAGTATCTGG ACCACTGCGG GAACCTCATG 780

AGCATGCACA ACGTCAAGAT TTTCATGTTC CAGCTGCTAC GGGGCCTCGC CTACTGTCAC 840

CACCGCAAGA TCCTGCACCG GGATCTGAAG CCCCAGAACC TGCTCATCAA TGAGAGAGGG 900

GAGCTGAAGC TGGCTGACTT TGGACTGGCC AGGGCCAAAT CAGTGCCCAC GAAGACCTAC 960

TCCAATGAGG TGGTGACCCT GTGGTACCGG CCCCCTGATG TGCTGCTGGG ATCCACAGAG 1020

TACTCCACCC CCATCGATAT GTGGGGCGTG GGCTGCATCC ACTACGAGAT GGCCACAGGG 1080

AGGCCCCTCT TTCCGGGCTC CACAGTCAAG GAGGAGCTGC ACCTCATCTT CCGCCTCCTC 1140

GGGACCCCCA CAGAAGAGAC GTGGCCCGGA GTGACCGCCT TCTCCGAGTT CCGCACCTAC 1200

AGCTTCCCCC GCTATCTCCC ACAGCCGCTC ATCAACCACG CGCCCAGGTT GGATACGGAT 1260

GGCATTCACC TCCTGAGCAG CCTGCTCCTG TATGAATCCA AGAGTCGCAT GTCAGCAGAG 1320

GCTGCCCTGA GTCACCCCTA CTTCCGGCCT CTGGGAGAGC GTGTGCACCA GCTTGAAGAC 1380

ACTGCCTCCA TCTTCTCCCT GAAGGAGATC CAGCTCCAGA AGGACCCAGG CTACCGCAGC 1440

TTGGCCTTCC AGCATCCAGG TAGGGGCTTG TGCCCTCCTG GCCCCTTCCT T 1491

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y kl+k+geGty++v+k+++k t+++vAlK+irle+e eg p+ta+rE+sllk+l+ +

Q: 172   YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLEAPP-  229

         7899********************************9.9****************9995.

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

             ++++ ++++l+Lv+   ++dLk++l+++ +  +s+++vk +++qll+glay+H++k

Q: 230   ----DLIH-TDRSLTLVLSTWDSDLKQYLDHCGN-LMSMHNVKIFMFQLLRGLAYCHHRK  283

         ....8899.899**********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         ilHRDlKpqNlLi+++g+lklaDfGlara s+p+kty++evvTlwYr+P++Llg++eYst

Q: 284   ILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYST  343

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

          +D+W+vgci  e++t +plf+g++ +++l+ if+llgtp+e++wp+v+ ++e++ +sfp

Q: 344   PIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRtYSFP  403

         *******************************************************99***

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         ++ ++ l ++ ++l++++++ll++ll ++ k+R+sa++al+h+yf

Q: 404   RYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHPYF  448

         ********************************************9

Domain Sequence
(FASTA)

YVKLDKLGEG TYATVFKGRS KLTENLVALK EIRLEHEEGA PCTAIREVSL LKNLEAPPDL 60

IHTDRSLTLV LSTWDSDLKQ YLDHCGNLMS MHNVKIFMFQ LLRGLAYCHH RKILHRDLKP 120

QNLLINERGE LKLADFGLAR AKSVPTKTYS NEVVTLWYRP PDVLLGSTEY STPIDMWGVG 180

CIHYEMATGR PLFPGSTVKE ELHLIFRLLG TPTEETWPGV TAFSEFRTYS FPRYLPQPLI 240

NHAPRLDTDG IHLLSSLLLY ESKSRMSAEA ALSHPYF 277

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013