EKS-CAJ-00053

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00053

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/RAF	375.6	3.3E-112	475	742	268

Status

Unreviewed

Ensembl Protein

ENSCJAP00000022734

UniProt Accession

F7HVR8;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100403547

Gene Synonyms/Alias

LOC100403547;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000012392	ENSCJAP00000022734	ENSCJAT00000024052
ENSCJAG00000012392	ENSCJAP00000022715	ENSCJAT00000024031
ENSCJAG00000012392	ENSCJAP00000043924	ENSCJAT00000054159
ENSCJAG00000012392	ENSCJAP00000017224	ENSCJAT00000018218

Organism

Callithrix jacchus

Functional Description

Protein Length

764

Protein Sequence
(FASTA)

MNEARVKETL RRCGASAEEC GRLQYALTCL RKVTGLGGEH KEDSGCSLLD ARRESGSGPS 60

TDTLSPASLP WPPGSSQLSR AGNSTQGPRS ISVSAIPASD SPTTSFSEGL SDTCIPLHAS 120

GRLTPRALHS FITPPTTPQL RRHTKLKPPR TPPPPSRKVF QLLPSFPTLT RSKSHESQLG 180

NRIDEVSSMR DLPHGSPQMV RRDIGLSVTH RFSTKSWLSQ VCHVCQKSMI FGVKCKHCRL 240

KCHNKCTKEA PACRISFLPL TRLRRTESVP SDINNPVDRA AEPHFGTLPK ALTKKEHPPA 300

MNHLDSSSNP SSTTSSTPSS PAPFPTSSNP SSATTPPNPS PGQRDSRFNF PAAYFIHHRQ 360

QFIFPVSSAG CCWKCLLIAE SLKEKSYNIS AFAQAAPLPE AADSTRFNDQ PKADVLEAHE 420

AEAEEPEAGK SEAEDDEDEV DDLPSSRRPW RGPISRKASQ TSVYLQEWDI PFEQVELGEP 480

IGQGRWGRVH RGRWHGEVAI RLLEMDGHNQ DHLKLFKKEV MNYRQTRHEN VVLFMGACMN 540

PRDLCLITTL NSFCKGRTLH SFVRDPKTSL DINKTRQIAQ EIIKGMGYLH AKGIVHKDLK 600

SKNVFYDNGK VVITDFGLFG ISGVVREGRR ENQLKLSHDW LCYLAPEIVR EMTPGKDEDQ 660

LPFSKAADVY AFGTVWYELQ ARDWPLKNQA AEASIWQIGS GEGMKRVLAS VSLGKEVSEI 720

LSACWAFDLQ ERPSFSLLMD MLEKLPKLNR RLSHPGHFWK SAEL 764

Nucleotide Sequence
(FASTA)

ATGAACGAGG CCAGGGTGAA GGAGACGCTG CGGCGCTGTG GGGCCAGTGC GGAGGAGTGT 60

GGCCGCCTGC AGTACGCCCT CACCTGCTTG CGGAAAGTGA CAGGCCTGGG AGGGGAACAC 120

AAGGAGGACT CGGGTTGTAG TTTGTTGGAT GCTCGGCGGG AAAGTGGCTC AGGGCCTTCC 180

ACGGACACCC TCTCACCAGC CAGCCTGCCC TGGCCCCCGG GCAGCTCTCA GCTGAGCAGA 240

GCAGGCAACA GCACCCAGGG CCCACGCTCC ATCTCCGTGT CAGCTATTCC CGCCTCTGAC 300

TCCCCCACCA CCAGCTTCAG TGAGGGCCTC TCGGACACCT GTATCCCCCT GCACGCCAGC 360

GGCCGGCTGA CCCCGCGGGC CCTGCACAGC TTCATCACCC CGCCCACCAC ACCCCAGCTG 420

CGACGGCACA CCAAGCTGAA GCCACCACGG ACGCCCCCGC CACCCAGCCG CAAGGTCTTC 480

CAGCTGCTGC CCAGCTTCCC CACGCTCACC CGGAGCAAGT CCCATGAGTC TCAGCTGGGG 540

AACCGCATCG ACGAGGTCTC CTCAATGAGA GATCTCCCGC ATGGATCCCC ACAGATGGTA 600

CGGAGGGATA TTGGGCTTTC GGTGACGCAC AGGTTCTCCA CCAAGTCTTG GCTGTCGCAG 660

GTCTGCCACG TGTGCCAGAA GAGCATGATA TTTGGAGTGA AGTGCAAGCA TTGCAGGTTG 720

AAGTGTCACA ACAAATGCAC CAAAGAAGCT CCTGCCTGTA GAATATCCTT CCTGCCACTA 780

ACTCGGCTTC GGAGGACAGA ATCTGTCCCT TCAGACATCA ACAACCCGGT GGACAGAGCA 840

GCCGAACCCC ACTTTGGAAC CCTCCCCAAA GCACTGACAA AGAAGGAGCA CCCTCCAGCC 900

ATGAATCACC TGGACTCCAG CAGCAACCCC TCCTCCACCA CCTCCTCCAC ACCCTCCTCG 960

CCAGCGCCCT TCCCGACATC ATCCAACCCA TCCAGTGCCA CCACGCCCCC AAACCCCTCA 1020

CCTGGCCAGC GGGACAGCAG GTTCAACTTC CCAGCTGCCT ACTTCATTCA TCATAGACAG 1080

CAGTTTATCT TTCCAGTGTC ATCTGCTGGC TGTTGCTGGA AATGCCTCCT TATTGCAGAA 1140

AGTTTAAAGG AAAAATCTTA CAACATTTCG GCCTTTGCAC AGGCAGCCCC GCTCCCCGAA 1200

GCCGCCGACA GTACCCGGTT CAACGATCAG CCGAAAGCAG ACGTGTTGGA GGCTCACGAA 1260

GCAGAGGCTG AGGAGCCAGA GGCTGGCAAG TCAGAGGCAG AAGACGACGA GGACGAGGTG 1320

GACGACTTGC CGAGCTCTCG CCGGCCCTGG CGGGGCCCCA TCTCTCGTAA GGCCAGCCAG 1380

ACCAGTGTGT ACCTGCAGGA GTGGGACATC CCCTTCGAGC AGGTAGAGCT GGGCGAGCCC 1440

ATCGGGCAGG GCCGCTGGGG CCGGGTGCAC CGCGGCCGCT GGCATGGCGA GGTGGCCATT 1500

CGCCTGCTGG AGATGGATGG CCACAACCAG GACCACCTGA AGCTCTTCAA GAAAGAGGTG 1560

ATGAACTACC GGCAGACACG GCACGAGAAC GTGGTGCTCT TCATGGGGGC CTGCATGAAC 1620

CCCCGGGACC TGTGCTTGAT CACCACCCTC AACAGCTTTT GCAAGGGGCG GACATTGCAC 1680

TCGTTTGTGA GGGACCCCAA GACGTCTCTG GACATCAACA AGACAAGGCA GATCGCTCAG 1740

GAGATCATCA AGGGCATGGG GTATCTTCAC GCTAAGGGCA TCGTACACAA AGACCTCAAA 1800

TCCAAGAACG TCTTCTATGA CAACGGCAAG GTGGTCATCA CAGACTTCGG GCTGTTCGGG 1860

ATCTCGGGCG TGGTCCGAGA GGGACGGCGT GAGAACCAGC TGAAGCTGTC CCACGACTGG 1920

CTGTGCTATC TGGCCCCAGA GATCGTGCGT GAGATGACCC CTGGGAAGGA CGAGGATCAG 1980

CTCCCATTCT CCAAAGCTGC TGACGTCTAT GCATTTGGGA CTGTCTGGTA TGAGCTGCAA 2040

GCGAGAGATT GGCCCTTGAA GAACCAAGCT GCGGAGGCAT CCATCTGGCA GATTGGAAGC 2100

GGGGAAGGAA TGAAGCGTGT CCTGGCCTCT GTCAGCCTGG GGAAGGAAGT CAGTGAGATC 2160

CTGTCAGCCT GCTGGGCTTT CGACCTGCAG GAGAGACCCA GCTTCAGCCT GCTGATGGAC 2220

ATGCTGGAGA AACTTCCCAA GCTGAACCGG CGGCTCTCCC ACCCCGGGCA CTTCTGGAAG 2280

TCAGCTGAGT TGTAG 2295

Domain Profile

S: 1     velaekiGsGrfGtvyrgkwhGdvavkllnveelseeqleaFkkevaaykktRhenivLF  60

         vel+e iG+Gr+G+v+rg+whG+va++ll+++ +++++l+ Fkkev++y++tRhen+vLF

Q: 475   VELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVLF  534

         67899*******************************************************

S: 61    mG.yvskpelaivt...slckgssLykllheqetkldlaklidiarqiaqgmdYLhakki  116

         mG ++++ +l ++t   s+ckg++L++++++ +t+ld++k+++ia++i++gm+YLhak+i

Q: 535   MGaCMNPRDLCLITtlnSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGI  594

         ***********99855579*****************************************

S: 117   lhkDlksknilleeglkvvitDFgllsvkrllsg.rrekqleipkgwilylapevirals  175

         +hkDlkskn+++++g kvvitDFgl+ ++ ++++ rre+ql+++++w++ylape++r+++

Q: 595   VHKDLKSKNVFYDNG-KVVITDFGLFGISGVVREgRRENQLKLSHDWLCYLAPEIVREMT  653

         ***************.***************9977*************************

S: 176   idleqdelpfskesDvyafGivlyellarelpykeesadqilfavgrG..lkpdlskvks  233

         +++++d+lpfsk++DvyafG+v+yel+ar++p+k+++a++ ++++g+G  +k++l++v

Q: 654   PGKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEASIWQIGSGegMKRVLASV--  711

         *********************************************99988********..

S: 234   klpkelkellleClkfekeeRPlftqilkkl  264

         +l+ke++e+l++C++f+ +eRP+f+ ++++l

Q: 712   SLGKEVSEILSACWAFDLQERPSFSLLMDML  742

         ***************************9985

Domain Sequence
(FASTA)

VELGEPIGQG RWGRVHRGRW HGEVAIRLLE MDGHNQDHLK LFKKEVMNYR QTRHENVVLF 60

MGACMNPRDL CLITTLNSFC KGRTLHSFVR DPKTSLDINK TRQIAQEIIK GMGYLHAKGI 120

VHKDLKSKNV FYDNGKVVIT DFGLFGISGV VREGRRENQL KLSHDWLCYL APEIVREMTP 180

GKDEDQLPFS KAADVYAFGT VWYELQARDW PLKNQAAEAS IWQIGSGEGM KRVLASVSLG 240

KEVSEILSAC WAFDLQERPS FSLLMDML 268

Keyword

Complete proteome; Metal-binding; Reference proteome; Zinc.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005622	; C:intracellular
GO:0005524	; F:ATP binding
GO:0046872	; F:metal ion binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0035556	; P:intracellular signal transduction

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR025561	; KSR_SAM-like_dom.
IPR002219	; Prot_Kinase_C-like_PE/DAG-bd.
IPR000719	; Prot_kinase_cat_dom.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF13543	; KSR1-SAM; 1.
PF07714	; Pkinase_Tyr; 1.

SMARTs

SM00109

; C1; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS00479	; ZF_DAG_PE_1; 1.
PS50081	; ZF_DAG_PE_2; 1.

Prints

Created Date

20-Feb-2013