EKS-CAJ-00297

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00297

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/BUB	385.5	2.3E-115	786	1051	266

Status

Unreviewed

Ensembl Protein

ENSCJAP00000024828

UniProt Accession

F6U7Z4;

Protein Name

Protein Synonyms/Alias

Gene Name

BUB1

Gene Synonyms/Alias

BUB1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000013468	ENSCJAP00000024828	ENSCJAT00000026251

Organism

Callithrix jacchus

Functional Description

Protein Length

1083

Protein Sequence
(FASTA)

MDTPENALQM FEAHMQSYKG NDPLGEWESY IQWVEENFPE NREYLATLLE HLMKEFLDKK 60

KYHNDPRFIN YCLKFAEYNS DLHQFFEFLY NHGIGTLSSL LYIAWAGHLE AQGELQHASA 120

VLRRGIQNQA EPRELLQQQY RLFQTRLTET HLPAQARTSE PLHNVQISNQ MVTSKSNPGN 180

SMACISKNQG SELSGVISSA CDKESNMEHR VIMISKSEYS VHSSLASKAD VQQVVMYCKE 240

KLIRGESEFS FEELRAQKYN QRRKHEQWVN EDRHYMKRKE ANAFEEQLLK QKMDELHKKL 300

HQVVETSHEE LPTSQERSEV NPACMGPSIG SQQELRAPCL PVIYHQTPVN MEKNPRKAPP 360

VVPPLANAIS AALVSPSTSQ SIPPPVPLKA QAVTDSMFAV ARTDAGCVNK STHEFKPQSG 420

TEIKEGYETH KVASTSSFHT TPNTSLGMVQ ATPSKVQPSP TVHTKEALGF IMNMFQAPTL 480

PDISDDKDEW QSLDQNEDAF EAQFQKNVRS SGAWGVNKII SSLSSAFHVF EDGNKENYGL 540

PQPQNKPTGT RTFGERSVSR FPSKPNEVPH AEEFLDDSTV WGIRCNKTLA PSPKSPGDFT 600

SAAQLASTPF HKLPVESVLI LEDKENVAAK QCTHVTLDSW EENVVPSRDR KFSPIQEKSP 660

EQAFSSEVYS ASLLRLSQPA AGGILTCEAE RGLEACRLTD TDTVIVEDPP DATAGLQAEQ 720

MQTSSLEEVD DPNFIVENPW DDKLIFKLLS GLSKPVSSYP NVFEWQCKLP AIKPKTEFQL 780

GSELIYVHHL LGEGAFAQVY EATQGEVNDA KNKQKFVLKV QKPANPWEFY IGTQLMERLK 840

PTMHHMVIKF YSAHLFQNGS ILVGELYSYG TLLNAINLYK NTPEKVMPQG LVISFAMRML 900

YMIEQVHDCE IIHGDIKPDN FILGNRFLEQ DDEDDLSAGL ALIDLGQSID MKLFPKGTAF 960

TAKCNTSGFQ CVEMLSNKPW NYQSDYFGVA ATVYCMLFGT YMKVKNEGGV WKPEGLFRRL 1020

PHLDMWNEFF HIMLNIPDCH HLPSLDLLRQ KLKKIFQQHY TNKIRALRNR LIGLLLECMR 1080

SRK 1083

Nucleotide Sequence
(FASTA)

ATGGACACCC CGGAAAATGC CCTTCAGATG TTTGAAGCCC ATATGCAGAG CTACAAGGGC 60

AATGACCCTC TTGGTGAATG GGAAAGCTAC ATACAGTGGG TAGAAGAGAA TTTTCCTGAG 120

AATAGAGAAT ACTTGGCAAC TTTACTAGAA CATTTAATGA AGGAATTTTT AGATAAGAAG 180

AAATACCACA ATGACCCAAG ATTCATCAAT TATTGTTTAA AATTTGCTGA GTACAACAGT 240

GACCTCCATC AGTTTTTTGA GTTTCTGTAC AACCATGGGA TTGGAACCCT GTCATCCCTT 300

CTGTACATAG CCTGGGCGGG GCATCTGGAA GCCCAAGGAG AGCTGCAGCA TGCCAGTGCT 360

GTCCTCCGGA GAGGAATTCA AAACCAGGCT GAACCTAGAG AGCTCCTGCA ACAACAGTAC 420

AGGTTATTTC AGACACGCCT CACTGAAACC CATTTGCCAG CTCAAGCTAG AACCTCAGAA 480

CCTCTGCATA ATGTTCAAAT TTCAAACCAA ATGGTAACAT CAAAATCAAA TCCAGGAAAT 540

AGTATGGCCT GTATTTCTAA GAATCAGGGT TCAGAGCTTT CAGGAGTGAT ATCTTCAGCT 600

TGTGATAAAG AGTCAAATAT GGAACACAGA GTGATCATGA TTTCTAAATC AGAATATTCT 660

GTGCACTCAT CTTTGGCATC CAAAGCTGAT GTTCAACAGG TTGTTATGTA TTGCAAGGAG 720

AAGCTTATTC GTGGGGAATC AGAATTTTCC TTTGAAGAAT TGAGAGCCCA GAAATACAAT 780

CAACGGAGAA AGCATGAGCA ATGGGTAAAT GAAGACAGAC ATTATATGAA AAGGAAAGAA 840

GCAAATGCTT TTGAAGAACA GCTATTAAAA CAGAAAATGG ATGAACTTCA TAAGAAGTTG 900

CATCAAGTGG TGGAGACATC CCATGAGGAG CTGCCCACTT CTCAGGAAAG GTCTGAGGTT 960

AATCCAGCAT GTATGGGACC AAGCATAGGC TCCCAGCAGG AACTGAGAGC TCCATGTCTT 1020

CCAGTCATCT ATCACCAGAC ACCAGTGAAC ATGGAAAAGA ACCCAAGAAA GGCACCTCCT 1080

GTTGTTCCTC CTTTGGCAAA TGCTATTTCT GCAGCTTTGG TGTCCCCATC TACTAGCCAG 1140

AGCATTCCTC CTCCTGTTCC TTTGAAAGCC CAGGCAGTAA CAGACTCCAT GTTTGCAGTG 1200

GCCAGAACGG ATGCTGGATG TGTGAATAAG AGTACTCATG AATTTAAGCC ACAGAGTGGA 1260

ACAGAGATAA AAGAAGGGTA TGAAACACAT AAGGTTGCCA GCACAAGTTC TTTCCACACA 1320

ACTCCAAACA CATCACTGGG AATGGTTCAG GCAACACCGT CCAAAGTGCA GCCATCACCC 1380

ACTGTGCACA CAAAAGAAGC ATTAGGTTTC ATAATGAATA TGTTTCAAGC TCCTACACTT 1440

CCTGATATTT CTGATGACAA AGATGAATGG CAATCTCTAG ATCAAAATGA AGATGCATTC 1500

GAAGCCCAGT TTCAAAAAAA TGTAAGGTCA TCTGGGGCTT GGGGAGTCAA TAAGATTATC 1560

TCTTCTTTGT CATCTGCTTT TCATGTGTTT GAAGATGGAA ACAAAGAAAA TTACGGATTA 1620

CCACAGCCTC AAAATAAACC AACAGGAACC AGGACCTTTG GAGAACGCTC TGTCAGCAGA 1680

TTTCCTTCAA AACCAAATGA AGTTCCTCAT GCTGAAGAGT TTTTGGATGA TTCAACCGTA 1740

TGGGGTATTC GCTGCAACAA AACCCTAGCA CCCAGTCCTA AGAGCCCAGG AGACTTCACA 1800

TCTGCTGCAC AACTTGCATC TACACCATTC CATAAACTTC CAGTGGAGTC AGTGCTCATT 1860

TTAGAAGATA AAGAAAATGT GGCAGCAAAA CAGTGCACCC ATGTGACTTT GGATTCTTGG 1920

GAAGAAAATG TGGTGCCTTC AAGGGACAGA AAATTCAGTC CAATTCAAGA GAAAAGCCCA 1980

GAACAGGCCT TCTCCTCTGA GGTGTATTCA GCATCCTTAC TCCGTCTGAG CCAGCCTGCT 2040

GCAGGTGGGA TACTTACCTG TGAGGCAGAG CGAGGCCTTG AGGCTTGCAG ACTCACAGAC 2100

ACTGACACTG TCATTGTAGA AGATCCTCCA GATGCTACTG CTGGGCTCCA AGCAGAACAG 2160

ATGCAGACGA GTTCACTTGA GGAAGTTGAT GATCCAAACT TCATTGTTGA GAACCCATGG 2220

GATGATAAGC TGATTTTCAA ACTTTTATCT GGGCTTTCTA AACCAGTGAG TTCCTATCCA 2280

AATGTTTTTG AATGGCAATG TAAACTTCCA GCCATCAAGC CCAAGACTGA ATTTCAATTG 2340

GGTTCTGAGC TGATCTATGT CCATCACCTT CTTGGAGAAG GAGCCTTTGC TCAGGTGTAT 2400

GAAGCTACCC AGGGAGAGGT GAATGATGCT AAAAATAAAC AGAAATTTGT TTTAAAGGTC 2460

CAGAAGCCTG CTAACCCCTG GGAATTCTAC ATTGGAACTC AGCTGATGGA GAGACTAAAG 2520

CCAACTATGC ATCACATGGT TATCAAGTTC TATTCTGCTC ACTTATTCCA GAATGGCAGT 2580

ATATTAGTAG GAGAGCTCTA CAGCTATGGA ACATTATTAA ATGCCATTAA CCTCTATAAA 2640

AATACCCCTG AAAAAGTGAT GCCTCAAGGT CTCGTTATCT CTTTTGCTAT GAGAATGCTT 2700

TACATGATTG AGCAAGTGCA TGACTGTGAA ATCATTCATG GAGACATTAA GCCAGACAAT 2760

TTCATACTTG GAAACAGATT TTTGGAACAG GATGATGAAG ATGATTTATC TGCTGGCTTG 2820

GCACTGATTG ACCTGGGTCA GAGTATAGAT ATGAAACTTT TTCCAAAAGG AACTGCATTC 2880

ACAGCAAAAT GTAACACATC TGGTTTTCAG TGTGTTGAGA TGCTCAGTAA CAAACCATGG 2940

AACTACCAGA GCGATTACTT TGGGGTTGCT GCAACAGTAT ATTGCATGCT CTTCGGCACT 3000

TACATGAAAG TGAAAAATGA AGGAGGAGTG TGGAAGCCTG AAGGTCTTTT TAGAAGGCTT 3060

CCTCATTTGG ATATGTGGAA TGAATTTTTT CACATCATGT TGAATATTCC GGATTGTCAT 3120

CATCTTCCAT CTTTGGATTT GTTAAGGCAA AAGCTGAAGA AAATATTTCA GCAACACTAT 3180

ACTAACAAGA TTAGGGCTCT ACGTAATAGG CTAATTGGAC TGCTCTTAGA ATGTATGCGT 3240

TCACGGAAAT AA 3252

Domain Profile

S: 2     eiekeigeGayakvykaeh....dsksgelvalKvekpansWefYIclqlkeRlkeeell  57

         ++++++geGa+a+vy+a++    d+k++++++lKv+kpan+WefYI +ql+eRlk ++++

Q: 786   YVHHLLGEGAFAQVYEATQgevnDAKNKQKFVLKVQKPANPWEFYIGTQLMERLK-PTMH  844

         799*******************9********************************.89**

S: 58    ksiieissallfqdasllvleyasygtlldlinkvkevtnkvmdeelvvllivqllkive  117

         +++i+++sa+lfq++s+lv e++sygtll++in++k++ +kvm++ lv+++++++l+++e

Q: 845   HMVIKFYSAHLFQNGSILVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIE  904

         ************************************************************

S: 118   klHeveIiHgDlkPdnfllgnrimdkadkdkeekglkliDfgrsiDmkllpdgtkfkgka  177

         ++H++eIiHgD+kPdnf+lgnr+ ++ d+d+ ++gl+liD+g+siDmkl+p+gt+f++k+

Q: 905   QVHDCEIIHGDIKPDNFILGNRFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTAFTAKC  964

         ************************************************************

S: 178   ktdafeciemlagkswsYqvDlfglaavihvllfgkyleviqeggswklkqkikrllkke  237

         +t++f+c+eml++k+w+Yq D+fg+aa+++++lfg+y++v++egg wk++  ++rl++ +

Q: 965   NTSGFQCVEMLSNKPWNYQSDYFGVAATVYCMLFGTYMKVKNEGGVWKPEGLFRRLPHLD  1024

         ************************************************************

S: 238   lwekiferlLNisdastlpsleelveek  265

         +w+++f+ +LNi+d+++lpsl+ l++ k

Q: 1025  MWNEFFHIMLNIPDCHHLPSLDLLRQ-K  1051

         ************************95.4

Domain Sequence
(FASTA)

YVHHLLGEGA FAQVYEATQG EVNDAKNKQK FVLKVQKPAN PWEFYIGTQL MERLKPTMHH 60

MVIKFYSAHL FQNGSILVGE LYSYGTLLNA INLYKNTPEK VMPQGLVISF AMRMLYMIEQ 120

VHDCEIIHGD IKPDNFILGN RFLEQDDEDD LSAGLALIDL GQSIDMKLFP KGTAFTAKCN 180

TSGFQCVEML SNKPWNYQSD YFGVAATVYC MLFGTYMKVK NEGGVWKPEG LFRRLPHLDM 240

WNEFFHIMLN IPDCHHLPSL DLLRQK 266

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR013212	; Mad3_BUB1_I.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR015661	; Ser/Thr_kinase_Bub1.

Pfam

PF08311	; Mad3_BUB1_I; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00777

; Mad3_BUB1_I; 1.

Prosites

PS51489	; BUB1_N; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013