EKS-CAJ-00095

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00095

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	419.1	2.8E-125	3720	4069	350

Status

Unreviewed

Ensembl Protein

ENSCJAP00000025149

UniProt Accession

F7CGE9;

Protein Name

Protein Synonyms/Alias

Gene Name

PRKDC

Gene Synonyms/Alias

PRKDC;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000013572	ENSCJAP00000025142	ENSCJAT00000026571
ENSCJAG00000013572	ENSCJAP00000025126	ENSCJAT00000026554
ENSCJAG00000013572	ENSCJAP00000051913	ENSCJAT00000054876
ENSCJAG00000013572	ENSCJAP00000025149	ENSCJAT00000026579

Organism

Callithrix jacchus

Functional Description

Protein Length

4129

Protein Sequence
(FASTA)

MAGSGAGVRC SLLRLQETLS AADRCGAALA GHQLIRGLGQ ECVLSGSPAL LALQTSLVFS 60

RDFGLLVFVR KSLNSIEFRE CREEILKFLC IFLEKMGQKM APYCLEIKNT CTSVYTKDRA 120

AKCKIPALDL LIKLLQTFRS SRLMDELKIG ELFSKFYGEL ALKKKIPDTV LEKVYELLGL 180

LGEVHPSEMI NNAENLFRAF LGELKTQMTS AVREPKLPVV AGCLKGLSSL LCNFTKSMEE 240

DPQTSKEIFN FVLKAIRPQI DLKRYAVPSA GLRLFALHAS QFSTCLLDKY VSLFEVLLKW 300

CAHTNVELKK AAQSALESFL KQVSYMVAKN AEMHKSKLQY FMEQFYGIIR NMDSNNKELS 360

IAIRGYGLFA GPCKVINAKD VDIMYIELIQ RCKQMFLTQT DIGDDRVYQM PSFLQSVASV 420

LLYLDTVPEV YTPVLEHLVV MQIDSFPQYS PKMQLVCCRA VVKVFLALAA KGPVLRNCIS 480

TVVHQGLIRI CSKPVVLPKG AESESEDHRA SGEVRTGKWK VPTYKDYVDL FRHLLSSDQM 540

MDSILADEAF FSVNSSHQSL NHLLYDEFVK SVLKIVEKLD LTLETQTVGE QENGDEAPGV 600

WVIPTSDPAA NLHPAKPKDF SAFINLVEFC REILPEKQVE FFEPWVYSFS HELILQSTRL 660

PLISGFYKLL SITVRNAKKI NYFEGVSPKS LQHSPEDPEK YSCFALFRKF GKEVAVKMKQ 720

YKDELLASCL TFLLSLPHDI IELDLRAYVP VLQMAFKLGL SHTPLAEVGL SALEEWSVYI 780

HKHEMQPYYK DILPFLDGYL KTSALSDETK SNWEVSALSR AAQKGFNKIV LKHLKKAKNL 840

SSSEAMSLEE IRIRIVQMLG SLGGQINKNL LTVASSDEMM KRYVAWDREK RLSFAVPFRE 900

MKPVIFLDVF LPRVTELALT ASDRQTKVAA CELLHSMVMF MLGKATQMPE GGQGVPPMYQ 960

LYKRTFPVLL RLACDVDQVT RQLYEPLVMQ LIHWFTNNKK FESQDTVALL EAILDGIVDS 1020

VDSTLRDFCG RCIREFLKWS IKQTTPQQQE KSPVNTKSLF KRLYSLALHP NAFKRLGASL 1080

AFNNIYREFR EEESLVEQFV FEAFVIYMES LALAHTDEKC LGTIQQCCDA IDHLCRIIEK 1140

KHVSLNKAKK RRVPRGFPPS ASLCLLDLVK WLLANCGRPQ TECRHKSIEL FYKFVPLLPG 1200

NRSPNLWLKD VLKEEGVSFL INIFEGGSCR QPSGILAQPT LLHLRGPFSL RATLCWLDLL 1260

LAALECYNTF IGERTVGAFQ VLGIEAQSSL LKAVAFFLES IAMHDIVAAE KCFGAGAAGT 1320

TPSPQEGERY NYSKCTVVVR IMEFTTTLLN TSPEGWKLLK KDLCNTHLMR VLVQTLCEPA 1380

SVGFNIGDIQ VMDHLPDVCV NLMKALKMSP YEDTLETHLR EKITARRIEE LCAVNLYGPD 1440

AQVHRSRLAA VVSACKQLHR AELLHAILPS QSTDLPHSLG TELLTLVYKS IAPGDERQCL 1500

PPLDPSCKQL ATGLLEFAFA FGGLCERLVS LLLNPVLLST PSLGSSQSSV IHFSHGEYFY 1560

SLFSETINTE LLKNMDLAVL ELMQSSMDNP KMVSAVLNGM LDQSFRERAS QKHQGLKLAT 1620

VILQHWKKCD SWWAKESPLE SKMAVLTLLA KLLQIDSSVS FNTSHGSFPE VFTTYLSLLA 1680

DTKLDLHLKG QAVTLLPFFT SLTGGSLEEL RRVLEQLIVA HFPMQSREFP AGTPRYNNYV 1740

DCMKKFLDAL EQSQSPMLLE LMTEVLCREH HHVMEDLFQS SFKRIARRGS CVTQVGLLES 1800

VYEMFRKDDP RLSFTRQSFV DRSLLTLLSH CSLDALREFF SRIVVDAIDV LKSRFTKLNE 1860

STFDTQITKK MGYYKMLDVM YSRLPKDDVH AKESKINQAF HGSCITEGNE LTKTLIKLCY 1920

DAFTENMAGE NQLLERRRLY HCAAYNCTIS VICCVFNELK FYQGFLFSEK PEKNLLIFEN 1980

LIDLKHRYNF PVEVEIPMER RKKYIEIRKE ARGAASGDSD GPSYMSSLSC LADSTLSEEM 2040

SQFDFSTGVQ SYSYSSQDPR PTTGRFRRRE QQDPAVHADV LELEMDELNR HECMAPLTAL 2100

VKHMHRSVGP PPGEEESVLR DLPPWMKFLH GKLGNPIVPL NIRLFLAKLI VNTEEVFRPY 2160

AKHWLSPLLQ LAVSENNGGE GIHYMVVEIV ATVLSWTGLA TPTGVPKDEV LANRLLNFLM 2220

KHVFHPKRTV YRHNLEIIKT LVECWKDCLS IPYRLIFEKF SGKDPNSKDN SVGIQLLGIV 2280

MANDLPPYDP QCGIQSSEYF QALVNNMSFV KYKEVYAAAA EVLGLILRYV MERKNILEES 2340

LCELVAKQLK QHQNTMEDKF IVCLNKVTKS FPPLADRFMN AVFFLLPKFH GVLKTLCLEV 2400

VLCRVEAMTE LYFQLKSKDF VQIMRHRDDE RQKVCLDIVY KVMPKLKPVE LRELLNPVVE 2460

FVSHPSTTCR EQMYNILMWI HDNYRDSESQ TDNDSQEIFK LTKDVLIQGL IDENPGLQLI 2520

IRNFWSHETR LPSNTLDRLL ALNSLYSPKI EVHFLSLATN FLLEMTSMSP DYPNPIFEHP 2580

LSECEFQECT IDSDWRFRST ILTPMFVETQ ASQGTLQTRT QEGSLSTRWS TAGQLRATQQ 2640

HYDFTPTQTA DGRSSFDWLT GSSTDPLADH TGPSSDSLLF AHKRSERSQR VPLKSVGPDF 2700

GKKRLGLPGD EVDNKVKGVA GRVDLLRLRR RFLRDQERLN LIYARKSLAE QKREKEMKSE 2760

LKMKQDAQVV LYRSYRHGDL PDIQIKHSSL ITPLQAVAQR DPIIAKLLFS SLFSGILKEM 2820

DKFKTLSEKN IITQKLLQDF SCFLSTTFSF FPPFVSCIQD ISCQHAALLS LDPAAVSASC 2880

LASLQQPVGI RLLEEALLRL LPSELPAKRV RGKARLPPDV LRWVELAKLY RSIGEYDVLR 2940

GIFSSEIGTK EITQNALLAE ARSNYSEAAK QYDEALNKQD WVDGEPTEAE KDFWELASLD 3000

CYNHLAEWKS LEYCSTASVD SENPPDLNKI WSEPFYQETY LPYMVRSKLK LLLQGEADQS 3060

LLTFIDKAMH GELQKVILEL HYSQEMSLLY LLQDDLDRAK YYIQNGIQSF MQSYSSIDVL 3120

LHRSRLTKLQ SVQALTEIQE FISFISKQGN LSSQVNLKRL LNTWTNRYPD AKMDPMNIWD 3180

DIITNRCFFL SKIEEKLTPP PEDSSMNVDE DGDPGDSGEM QEEQEEDISS LIRSCKFSMK 3240

MKMMDSARKQ NNFSLAMKLL KELHKESKTR DDWLVSWVQS YCRLSHCRSR AQRCSEQVLT 3300

VLKTVSLLDE NNVSSYLSKN ILAFRDQNIL LGTTYRIIAN ALSSEPACLA EIEEDKARTI 3360

LELSGSSSED SEKVIAGLYQ RAFQHLSEAV QAAEEEAQPS SWSCGPAAGV IDAYMTLADF 3420

CDQQLRKEEE NATVTDSAEL QAYPALVVEK MLKALKLNSN EARLKFPRLL QIIERYPEET 3480

LSLMTKEMSS VPCWQFIGWI SHMVALLDKD QAIAVQHTVE EITDNYPQAI IYPFIISSES 3540

YSFKDTSTGH KNKEFVARIK SKLDHGGVIQ DFINALDQLS NPELLFKDWS NDVRAELAKT 3600

PVNKKNIEKM YERMYTTLGD PKAPGLGAFR RKFIQTFGKE FDKHFGKGGS KLPRMKLSDF 3660

NDITNMLLLK MNKDSKPPGN LKEWSPWMSD FKVEFLRNEL EIPGQYDGRG KPLLEYHVRI 3720

AGFDERVTVM ASMRRPKRII IRGHDETEHP FLVKGGEDLR QDQRVEQLFQ VMNGILAGDS 3780

ACSQRALQLR TYSVVPMTSR LGLIEWLENT VTLKDLLLNT MSQEEKAAYL SDPKAPLCEY 3840

RDWLTKMSGK HDVGAYMLMY KGANRTETVT SFRKRESKVP ADLLKRAFVR MSTSPQTFLA 3900

LRSHFASSHA LICISHWILG IGDRHLNNFM VAMETGGMIG IDFGHAFGSA TQFLPIPELM 3960

PFRLTRQFIN LMLPMKEMGL MYSVMVHALR AFRSDPGLLT NTMDVFVKDP SFDWKNFEQK 4020

MLKKGGSWIQ DINVAEKNWY PRQKICYAKR KLAGANPAVI TCDELLLGHE KAPAFRDYVA 4080

VARGSKDHNI RAREPEGGLS EETQVKCLMD QATDPNILGR TWEGWEPWM 4129

Nucleotide Sequence
(FASTA)

ATGGCGGGCT CCGGAGCCGG TGTGCGTTGC TCCCTGCTGC GGCTGCAGGA GACCTTGTCC 60

GCCGCGGACC GCTGCGGTGC TGCCCTGGCC GGTCATCAGC TGATCCGCGG CCTGGGGCAG 120

GAATGCGTGC TAAGCGGCAG CCCCGCGTTG CTGGCATTAC AGACATCTCT AGTTTTTTCC 180

AGAGATTTCG GTTTGCTTGT ATTTGTCCGG AAGTCACTCA ACAGTATTGA ATTTCGTGAA 240

TGTAGAGAAG AAATCCTAAA GTTTTTATGT ATTTTCTTAG AAAAAATGGG CCAGAAGATG 300

GCGCCTTACT GTCTTGAAAT TAAGAATACT TGTACCAGTG TTTATACAAA AGATAGAGCT 360

GCTAAATGTA AAATTCCAGC CCTGGACCTT CTTATAAAGT TACTTCAGAC ATTTAGAAGT 420

TCTAGACTCA TGGATGAATT GAAAATTGGA GAATTGTTTA GTAAATTCTA TGGAGAACTT 480

GCATTGAAAA AAAAAATACC AGATACAGTT TTAGAAAAAG TATATGAGCT CTTGGGATTA 540

TTGGGTGAAG TTCATCCTAG TGAGATGATA AACAATGCGG AAAACCTGTT CCGTGCTTTT 600

CTGGGGGAAC TAAAGACCCA GATGACATCA GCAGTGAGAG AGCCCAAGCT ACCTGTTGTG 660

GCAGGCTGTC TGAAGGGGTT GTCCTCGCTT CTGTGCAACT TCACAAAGTC CATGGAAGAA 720

GATCCCCAGA CTTCAAAGGA GATTTTTAAT TTTGTTCTGA AGGCAATCCG TCCTCAGATT 780

GATCTGAAGA GATATGCCGT GCCCTCAGCT GGCTTGCGCT TATTTGCCCT GCACGCATCT 840

CAGTTTAGCA CCTGCCTTCT GGACAAGTAC GTGTCTCTAT TTGAAGTCCT GCTAAAGTGG 900

TGTGCCCACA CAAATGTAGA ATTGAAAAAA GCTGCACAAT CAGCCCTGGA ATCCTTTCTG 960

AAACAGGTTT CTTATATGGT GGCGAAAAAT GCAGAAATGC ATAAGAGTAA GCTGCAGTAC 1020

TTTATGGAGC AGTTTTATGG GATCATCAGA AACATGGATT CAAACAACAA GGAGTTATCC 1080

ATTGCTATCC GTGGATATGG ACTTTTCGCA GGACCTTGCA AGGTTATAAA TGCAAAAGAT 1140

GTTGACATCA TGTACATTGA GCTCATTCAG CGCTGCAAGC AGATGTTCCT CACCCAGACG 1200

GACATTGGTG ATGACCGTGT TTATCAGATG CCAAGCTTCC TCCAGTCTGT TGCAAGTGTC 1260

TTACTGTACC TTGACACTGT TCCTGAGGTA TATACTCCAG TTCTGGAGCA CCTCGTGGTG 1320

ATGCAGATAG ACAGTTTCCC ACAGTACAGT CCAAAAATGC AGTTGGTGTG TTGCAGAGCC 1380

GTAGTGAAGG TGTTTCTAGC CTTGGCAGCA AAAGGACCAG TTCTCAGGAA TTGCATTAGT 1440

ACTGTGGTGC ATCAGGGGTT AATCAGAATA TGTTCTAAAC CAGTGGTCCT TCCAAAGGGT 1500

GCTGAGTCTG AATCTGAAGA CCACCGTGCT TCAGGGGAAG TCAGAACTGG CAAATGGAAG 1560

GTGCCCACAT ACAAAGACTA TGTGGATCTC TTCAGACATC TCCTGAGCTC TGACCAGATG 1620

ATGGATTCTA TTTTAGCAGA TGAAGCATTT TTCTCTGTGA ATTCCTCCCA TCAAAGCCTG 1680

AATCATTTAC TTTATGATGA ATTTGTAAAA TCTGTTTTGA AGATTGTTGA GAAGTTGGAT 1740

CTTACACTAG AAACACAGAC TGTTGGGGAA CAAGAGAATG GAGATGAGGC GCCTGGTGTT 1800

TGGGTGATCC CGACTTCAGA TCCAGCGGCT AACTTGCATC CAGCTAAACC TAAAGATTTT 1860

TCGGCTTTCA TTAACCTGGT GGAATTTTGC AGAGAGATTC TCCCTGAGAA ACAAGTTGAA 1920

TTTTTTGAAC CATGGGTGTA CTCATTTTCA CATGAGTTAA TTTTACAGTC GACAAGATTG 1980

CCCCTCATCA GTGGTTTCTA CAAATTGCTT TCTATTACAG TAAGAAATGC CAAGAAAATA 2040

AATTATTTTG AGGGAGTTAG TCCAAAGAGT CTGCAACACT CTCCTGAAGA CCCAGAAAAG 2100

TATTCTTGCT TTGCTTTATT TAGGAAATTT GGCAAAGAGG TGGCAGTTAA AATGAAGCAA 2160

TACAAAGACG AACTTTTGGC CTCCTGTTTG ACCTTTCTTC TGTCCCTCCC ACATGACATC 2220

ATTGAACTCG ATCTTAGAGC CTACGTTCCT GTGCTGCAGA TGGCTTTCAA ACTGGGCCTG 2280

AGCCATACCC CCTTGGCAGA AGTAGGCCTG AGTGCTCTAG AAGAATGGTC AGTTTACATC 2340

CACAAACATG AAATGCAGCC TTATTACAAA GATATTCTCC CCTTCCTGGA TGGGTACCTG 2400

AAGACTTCAG CCTTGTCAGA TGAGACCAAG AGTAACTGGG AAGTGTCTGC TCTCTCTCGG 2460

GCTGCCCAGA AAGGATTTAA TAAAATCGTA TTAAAGCATC TGAAGAAGGC AAAGAACCTT 2520

TCATCAAGTG AAGCAATGTC CTTAGAAGAA ATAAGAATTA GAATAGTACA AATGCTTGGA 2580

TCTCTGGGAG GACAAATAAA CAAAAATCTT CTGACAGTTG CCTCCTCAGA TGAGATGATG 2640

AAGCGTTATG TGGCCTGGGA CAGAGAGAAG CGGCTGAGCT TTGCAGTGCC CTTTAGAGAG 2700

ATGAAGCCTG TCATTTTCCT GGATGTGTTT CTTCCTCGGG TCACAGAATT GGCACTGACA 2760

GCCAGTGACA GACAAACTAA AGTTGCAGCC TGTGAACTTT TACATAGCAT GGTCATGTTT 2820

ATGTTGGGCA AAGCCACGCA GATGCCGGAA GGGGGACAGG GAGTCCCACC CATGTACCAG 2880

CTCTATAAGC GGACGTTTCC TGTGCTGCTT CGACTTGCGT GCGATGTTGA TCAGGTGACA 2940

AGGCAACTAT ACGAGCCACT GGTTATGCAG CTAATTCACT GGTTCACTAA CAATAAGAAA 3000

TTTGAAAGTC AGGATACTGT CGCCTTACTG GAAGCTATAT TGGATGGAAT CGTGGACTCT 3060

GTTGACAGTA CGTTAAGAGA TTTCTGTGGT CGGTGTATTC GAGAATTCCT TAAGTGGTCC 3120

ATTAAACAGA CAACACCACA GCAGCAGGAG AAGAGTCCAG TAAACACCAA ATCACTTTTC 3180

AAGCGACTGT ACAGCCTCGC ACTTCACCCC AATGCTTTCA AGAGGCTGGG AGCATCACTT 3240

GCCTTTAATA ATATCTATAG GGAATTCAGG GAAGAAGAGT CTCTGGTGGA ACAGTTTGTG 3300

TTCGAAGCCT TTGTGATATA CATGGAAAGT CTGGCCTTAG CACATACAGA CGAGAAGTGC 3360

TTAGGTACAA TCCAACAGTG TTGTGATGCC ATCGATCACC TATGCCGCAT CATTGAAAAG 3420

AAGCATGTTT CCTTAAACAA AGCAAAAAAA CGACGTGTGC CTCGAGGATT TCCGCCGTCA 3480

GCATCATTGT GTTTATTGGA TCTGGTCAAG TGGCTTTTAG CTAATTGTGG GAGGCCCCAG 3540

ACAGAATGTC GACACAAATC CATTGAACTC TTTTATAAAT TCGTTCCTTT ATTGCCAGGC 3600

AATAGATCCC CTAATCTATG GCTGAAAGAT GTTCTCAAGG AAGAAGGTGT CTCTTTTCTC 3660

ATCAACATCT TTGAGGGGGG CAGCTGTCGC CAGCCCTCAG GTATCCTGGC TCAGCCCACC 3720

CTCCTGCACC TGCGGGGGCC CTTCAGCCTT AGGGCCACGC TTTGCTGGCT GGACCTGCTT 3780

CTGGCTGCAC TGGAATGCTA CAACACGTTC ATCGGGGAGA GAACTGTGGG GGCGTTCCAG 3840

GTCCTAGGTA TTGAAGCACA GTCTTCACTT TTGAAAGCAG TGGCTTTCTT TTTAGAAAGC 3900

ATTGCTATGC ATGACATTGT AGCAGCAGAA AAGTGCTTTG GCGCTGGGGC AGCAGGTACC 3960

ACACCAAGCC CACAGGAGGG AGAAAGGTAC AACTATAGCA AATGCACCGT CGTCGTTCGG 4020

ATCATGGAGT TCACCACAAC TCTCTTGAAC ACCTCCCCTG AAGGGTGGAA GCTCCTGAAG 4080

AAGGACTTGT GTAACACACA CCTGATGAGA GTCCTGGTGC AGACGCTGTG TGAGCCCGCG 4140

AGCGTAGGGT TCAACATCGG GGACATCCAG GTTATGGATC ATCTTCCTGA TGTTTGTGTG 4200

AACCTGATGA AAGCGCTAAA GATGTCCCCA TATGAAGATA CGCTAGAGAC CCACCTGAGA 4260

GAGAAAATAA CAGCACGGAG GATTGAGGAG CTTTGTGCCG TCAACTTGTA TGGCCCTGAT 4320

GCACAAGTGC ACAGGAGCAG GCTGGCTGCT GTTGTGTCTG CCTGCAAGCA GCTTCACAGA 4380

GCTGAGCTTC TGCATGCTAT ATTACCATCT CAGTCCACAG ATCTGCCTCA TTCTCTCGGC 4440

ACAGAGCTTC TTACCCTGGT TTATAAAAGC ATTGCTCCTG GAGATGAGAG ACAGTGTCTG 4500

CCTCCTTTAG ACCCCAGTTG TAAGCAGCTG GCCACCGGAC TTCTGGAGTT TGCCTTTGCT 4560

TTTGGAGGAC TGTGTGAGCG CCTTGTGAGT CTTCTCCTGA ACCCAGTACT GCTGTCCACG 4620

CCATCCTTGG GCAGCTCACA GAGCAGCGTC ATCCACTTCT CTCATGGGGA GTATTTCTAT 4680

AGCTTGTTCT CAGAAACGAT CAACACAGAA TTGTTGAAAA ATATGGATCT TGCTGTATTG 4740

GAGCTCATGC AGTCATCAAT GGACAATCCC AAAATGGTGA GTGCCGTTTT GAACGGCATG 4800

CTAGACCAGA GCTTCAGGGA GCGAGCAAGC CAGAAACACC AAGGACTGAA ACTTGCAACT 4860

GTGATTCTGC AGCACTGGAA GAAGTGTGAT TCATGGTGGG CCAAGGAATC TCCTCTCGAA 4920

AGTAAAATGG CAGTGCTGAC CTTACTGGCA AAACTTTTAC AGATTGATTC ATCTGTATCT 4980

TTTAATACAA GCCATGGTTC ATTCCCTGAA GTCTTTACGA CATATCTTAG TCTACTTGCT 5040

GACACAAAGC TGGATCTACA TTTAAAGGGC CAAGCTGTCA CTCTTCTTCC GTTCTTCACC 5100

AGCCTCACTG GGGGTAGTCT GGAGGAACTC AGGCGTGTTC TGGAGCAGCT CATTGTCGCT 5160

CACTTCCCCA TGCAGTCCAG GGAATTTCCC GCAGGAACTC CGCGGTACAA TAATTACGTG 5220

GACTGCATGA AAAAGTTTCT AGATGCACTG GAACAATCTC AGAGTCCTAT GTTGTTGGAA 5280

TTGATGACAG AAGTTCTTTG TCGGGAACAC CATCATGTCA TGGAAGACTT ATTTCAGTCC 5340

AGTTTCAAGA GGATTGCCAG AAGGGGTTCA TGCGTTACAC AAGTAGGCCT TCTGGAAAGT 5400

GTATACGAAA TGTTCAGGAA GGACGACCCC CGCCTAAGTT TCACCCGCCA GTCCTTTGTG 5460

GATCGCTCCC TTCTCACTCT GTTGTCTCAC TGCAGCCTGG ATGCTTTGAG GGAATTCTTC 5520

AGCAGAATTG TGGTGGATGC CATTGATGTA TTGAAGTCCA GGTTTACAAA GCTGAATGAA 5580

TCTACCTTTG ATACTCAAAT CACCAAGAAG ATGGGCTACT ATAAGATGCT AGATGTGATG 5640

TACTCTCGTC TTCCCAAAGA TGACGTTCAC GCTAAGGAAT CAAAGATTAA TCAGGCCTTC 5700

CATGGCTCAT GTATTACAGA AGGAAATGAA CTTACAAAGA CACTGATTAA GTTGTGCTAT 5760

GACGCATTTA CAGAGAACAT GGCAGGAGAG AATCAGCTGC TAGAGAGGAG AAGGCTTTAC 5820

CATTGTGCAG CATACAACTG CACCATATCT GTCATCTGCT GCGTCTTCAA TGAGTTAAAA 5880

TTTTACCAAG GGTTTCTGTT CAGTGAAAAA CCAGAAAAGA ACTTGCTTAT TTTTGAAAAT 5940

CTGATTGACC TGAAGCACCG CTATAATTTT CCTGTAGAAG TTGAGATTCC TATGGAGAGA 6000

AGGAAAAAGT ACATTGAAAT TAGAAAAGAA GCCAGAGGAG CAGCAAGTGG GGATTCAGAT 6060

GGTCCTTCCT ATATGTCTTC TCTGTCATGT TTGGCAGACA GTACCCTGAG TGAGGAAATG 6120

AGTCAATTTG ATTTCTCAAC CGGAGTTCAG AGCTATTCAT ATAGCTCCCA AGACCCTAGA 6180

CCTACCACTG GTCGTTTTCG GAGACGGGAG CAGCAGGACC CTGCAGTGCA TGCTGACGTG 6240

CTGGAGCTGG AAATGGATGA GCTCAATCGG CACGAGTGCA TGGCGCCCCT GACTGCCCTG 6300

GTGAAGCACA TGCACAGAAG CGTGGGCCCA CCTCCAGGAG AAGAGGAGTC AGTGCTAAGA 6360

GATCTTCCTC CTTGGATGAA ATTTCTCCAT GGCAAACTGG GAAATCCAAT AGTACCATTA 6420

AATATCCGTC TCTTCTTAGC CAAGCTTATT GTTAATACAG AAGAGGTCTT TCGCCCTTAT 6480

GCGAAGCACT GGCTTAGCCC CTTGCTGCAG CTGGCTGTTT CTGAAAACAA TGGAGGAGAA 6540

GGAATTCACT ACATGGTGGT TGAGATAGTG GCCACTGTTC TTTCATGGAC AGGCTTGGCC 6600

ACTCCAACAG GGGTCCCTAA AGATGAAGTG TTAGCAAATC GATTGCTTAA TTTCCTAATG 6660

AAACACGTCT TTCATCCAAA AAGAACTGTG TATAGACACA ACCTTGAAAT TATAAAGACC 6720

CTTGTGGAGT GCTGGAAGGA TTGCTTATCC ATCCCTTATA GGTTAATATT TGAAAAGTTT 6780

TCCGGTAAAG ATCCTAATTC TAAAGACAAC TCAGTAGGGA TTCAATTGCT AGGCATCGTG 6840

ATGGCCAATG ACCTGCCTCC CTATGACCCA CAGTGTGGCA TCCAGAGTAG CGAATACTTT 6900

CAAGCTTTGG TGAATAATAT GTCCTTTGTA AAATATAAGG AAGTGTATGC TGCTGCGGCA 6960

GAAGTTCTAG GACTGATACT TCGATATGTT ATGGAGAGAA AAAACATACT GGAGGAGTCT 7020

CTGTGTGAAC TGGTTGCGAA ACAATTGAAA CAACATCAGA ATACTATGGA GGACAAGTTT 7080

ATTGTGTGCT TGAACAAAGT GACCAAGAGC TTCCCTCCTC TTGCAGACAG GTTCATGAAT 7140

GCTGTGTTCT TTCTGCTACC AAAATTTCAT GGAGTGTTGA AAACACTCTG TCTGGAGGTG 7200

GTACTTTGTC GTGTGGAGGC AATGACAGAG CTGTACTTCC AGTTAAAGAG CAAGGACTTC 7260

GTTCAAATCA TGAGACATAG AGATGATGAA AGACAAAAAG TGTGTTTGGA CATAGTTTAT 7320

AAGGTGATGC CAAAATTGAA ACCAGTTGAA CTCCGAGAAC TTCTGAACCC TGTTGTGGAA 7380

TTTGTTTCCC ATCCTTCTAC GACATGTAGG GAACAAATGT ATAATATTCT CATGTGGATT 7440

CATGACAATT ACAGAGATTC AGAAAGTCAG ACAGATAATG ACTCCCAGGA GATATTTAAG 7500

TTGACAAAAG ATGTGCTGAT TCAAGGATTG ATCGATGAGA ACCCTGGACT TCAATTAATC 7560

ATTCGAAATT TCTGGAGCCA TGAAACTAGG TTGCCTTCAA ATACCTTGGA CCGGTTGCTG 7620

GCACTGAATT CCTTATATTC TCCTAAGATA GAAGTGCACT TTTTAAGTTT AGCAACAAAT 7680

TTTCTGCTTG AAATGACCAG CATGAGCCCA GATTATCCTA ACCCCATATT CGAGCATCCT 7740

CTGTCCGAAT GCGAATTTCA GGAATGCACC ATTGATTCTG ACTGGCGTTT CCGAAGTACT 7800

ATTCTCACTC CAATGTTTGT GGAGACCCAG GCGTCTCAGG GGACTCTCCA GACCCGTACC 7860

CAGGAAGGGT CCCTCTCAAC TCGCTGGTCG ACGGCGGGGC AGTTAAGGGC CACCCAGCAG 7920

CACTATGACT TCACACCGAC ACAGACTGCA GATGGAAGAA GCTCGTTTGA TTGGCTGACC 7980

GGGAGCAGCA CTGACCCGTT GGCCGACCAC ACCGGCCCCT CATCTGACTC CTTGCTGTTT 8040

GCCCACAAGA GGAGTGAAAG GTCACAGAGA GTACCCTTGA AGTCAGTGGG GCCTGATTTT 8100

GGAAAGAAAA GGCTGGGCCT TCCAGGGGAC GAGGTGGATA ACAAAGTGAA AGGTGTAGCT 8160

GGCCGGGTGG ACCTACTGCG GCTGCGCAGA CGGTTTCTGA GGGACCAGGA GAGGCTCAAT 8220

TTGATTTATG CCAGAAAAAG CCTTGCTGAG CAAAAACGAG AGAAGGAAAT GAAGAGCGAG 8280

TTAAAAATGA AGCAGGATGC CCAGGTCGTT CTGTACAGAA GCTACCGGCA TGGAGACCTT 8340

CCTGACATTC AGATCAAGCA CAGCAGCCTC ATCACCCCGT TGCAGGCGGT AGCCCAGAGA 8400

GACCCAATAA TTGCAAAACT GCTTTTTAGC AGCTTGTTTT CTGGAATTTT GAAAGAGATG 8460

GATAAATTTA AGACACTATC TGAAAAAAAC ATCATCACTC AGAAGTTGCT CCAAGACTTC 8520

AGTTGTTTTC TTAGTACCAC CTTCTCTTTC TTTCCACCTT TTGTCTCTTG TATCCAGGAC 8580

ATCAGCTGCC AGCATGCAGC CCTGCTGAGC CTCGACCCTG CAGCCGTGAG TGCCAGCTGC 8640

CTGGCCAGCC TACAGCAGCC TGTGGGCATT CGCCTGCTGG AGGAGGCTCT GCTCCGCCTG 8700

CTGCCCTCTG AGCTGCCTGC CAAGCGAGTC CGTGGGAAGG CCCGCCTTCC TCCTGATGTC 8760

CTTAGATGGG TGGAGCTTGC TAAGCTTTAT AGATCAATTG GAGAATACGA CGTCCTCCGC 8820

GGTATTTTTA GCAGTGAGAT AGGAACAAAG GAAATCACTC AGAACGCATT ATTAGCAGAA 8880

GCCAGAAGTA ATTATTCTGA AGCTGCTAAG CAGTATGATG AGGCTCTCAA TAAACAAGAC 8940

TGGGTAGATG GTGAGCCCAC AGAAGCCGAG AAGGATTTTT GGGAACTTGC ATCCCTTGAC 9000

TGTTACAACC ATCTTGCTGA GTGGAAATCA CTTGAATACT GTTCTACAGC CAGTGTAGAC 9060

AGTGAGAACC CTCCAGACCT AAATAAAATC TGGAGTGAGC CATTTTATCA GGAGACGTAT 9120

CTACCTTACA TGGTCCGCAG CAAGCTGAAG CTGCTGCTCC AAGGAGAGGC TGACCAGTCC 9180

CTGCTGACGT TTATTGACAA AGCTATGCAT GGGGAACTCC AGAAGGTGAT TCTAGAGCTT 9240

CATTACAGTC AGGAGATGAG TCTGCTCTAC CTCTTGCAAG ATGACCTTGA CAGAGCCAAA 9300

TATTACATTC AAAATGGCAT TCAGAGTTTT ATGCAGAGTT ATTCTAGTAT TGATGTCCTC 9360

TTACACCGAA GTAGACTTAC CAAATTGCAG TCTGTACAGG CTTTAACAGA AATTCAGGAG 9420

TTCATCAGCT TTATAAGCAA ACAAGGGAAT TTATCATCTC AAGTTAACCT CAAGAGACTT 9480

CTGAACACCT GGACAAACAG ATATCCAGAT GCTAAAATGG ACCCAATGAA CATCTGGGAT 9540

GACATCATCA CAAATCGATG TTTCTTTCTC AGCAAAATAG AGGAGAAGCT TACCCCTCCT 9600

CCAGAAGATA GCAGTATGAA TGTGGATGAA GATGGAGACC CAGGTGACAG CGGGGAAATG 9660

CAAGAAGAGC AGGAAGAAGA CATCAGCTCC CTGATCAGGA GCTGCAAGTT TTCCATGAAA 9720

ATGAAAATGA TGGACAGCGC CCGGAAGCAG AACAATTTCT CACTTGCCAT GAAACTACTG 9780

AAGGAGCTGC ATAAAGAGTC AAAAACCAGA GATGATTGGC TGGTGAGCTG GGTGCAGAGC 9840

TACTGCCGCC TGAGCCACTG CCGGAGCCGG GCCCAGCGCT GCTCTGAACA GGTTCTCACT 9900

GTGCTGAAAA CAGTCTCTTT GTTGGATGAG AACAACGTAT CAAGCTACTT AAGCAAAAAC 9960

ATTCTGGCTT TCCGTGATCA GAACATTCTC TTGGGTACAA CTTACAGAAT CATAGCTAAT 10020

GCTCTCAGCA GTGAGCCAGC CTGCCTTGCT GAAATCGAGG AGGACAAGGC TAGAACAATC 10080

TTAGAGCTTT CTGGATCCAG TTCAGAGGAT TCAGAGAAGG TGATTGCAGG TCTGTACCAG 10140

AGAGCATTCC AGCACCTCTC TGAGGCCGTG CAGGCGGCTG AGGAGGAGGC TCAGCCTTCC 10200

TCCTGGAGCT GTGGGCCTGC AGCTGGGGTG ATTGATGCTT ACATGACTCT GGCAGATTTC 10260

TGTGACCAAC AGCTGCGGAA GGAGGAAGAG AATGCAACAG TTACTGATTC TGCAGAACTG 10320

CAGGCGTATC CAGCACTTGT GGTGGAGAAA ATGTTGAAAG CTTTAAAATT AAATTCCAAT 10380

GAAGCCAGAT TAAAGTTTCC TAGATTACTT CAGATTATAG AACGGTATCC AGAGGAGACC 10440

TTGAGCCTCA TGACAAAAGA GATGTCTTCC GTTCCCTGCT GGCAGTTTAT CGGCTGGATC 10500

AGCCACATGG TGGCCTTACT GGATAAAGAC CAAGCCATTG CTGTTCAGCA CACCGTGGAA 10560

GAAATCACCG ATAACTACCC TCAGGCTATT ATTTATCCCT TCATCATAAG CAGTGAAAGC 10620

TATTCCTTCA AGGATACTTC TACTGGTCAT AAGAATAAGG AGTTTGTGGC AAGGATTAAA 10680

AGTAAGTTGG ATCATGGAGG AGTGATTCAA GATTTTATTA ATGCCTTAGA TCAGCTCTCT 10740

AATCCTGAAC TGCTTTTTAA GGACTGGAGC AATGATGTAA GAGCTGAACT AGCAAAAACC 10800

CCTGTAAATA AAAAAAACAT TGAAAAAATG TATGAAAGAA TGTATACAAC CTTGGGTGAC 10860

CCAAAGGCTC CAGGCCTGGG AGCCTTTAGA AGGAAGTTTA TTCAGACCTT TGGAAAAGAA 10920

TTTGATAAAC ATTTTGGGAA AGGAGGGTCT AAGCTACCGA GAATGAAGCT CAGTGACTTC 10980

AATGACATTA CCAACATGCT ACTTTTAAAA ATGAACAAAG ACTCAAAGCC CCCTGGGAAT 11040

CTGAAAGAAT GGTCGCCGTG GATGAGCGAC TTCAAAGTGG AGTTCCTGAG AAATGAGCTG 11100

GAGATTCCTG GTCAATATGA TGGTAGGGGA AAGCCGTTGC TAGAGTACCA CGTGCGAATC 11160

GCCGGTTTTG ATGAGCGGGT GACAGTCATG GCCTCTATGA GAAGGCCCAA GCGCATCATC 11220

ATCCGTGGCC ATGATGAGAC GGAGCACCCT TTCCTAGTAA AGGGTGGCGA GGACCTGCGG 11280

CAGGACCAGC GTGTGGAGCA GCTCTTCCAG GTCATGAATG GGATCCTAGC CGGAGACTCC 11340

GCCTGCAGCC AGAGGGCCCT GCAGCTGAGG ACCTACAGCG TGGTGCCCAT GACCTCCAGG 11400

TTAGGATTAA TTGAGTGGCT TGAAAATACT GTTACCTTGA AGGACCTTCT TTTGAACACC 11460

ATGTCACAAG AGGAGAAGGC GGCTTACCTG AGTGATCCCA AGGCACCACT ATGTGAATAC 11520

AGAGACTGGC TGACAAAAAT GTCAGGAAAG CATGATGTTG GAGCTTACAT GCTAATGTAT 11580

AAGGGAGCTA ATCGTACTGA AACGGTCACG TCTTTTAGAA AACGAGAAAG TAAAGTGCCT 11640

GCCGATCTCT TAAAGCGGGC CTTCGTGAGG ATGAGTACAA GCCCCCAGAC CTTCCTGGCA 11700

CTCCGCTCGC ACTTCGCCAG CTCTCACGCT CTAATATGCA TCAGCCACTG GATCCTCGGC 11760

ATCGGAGACA GACACCTGAA CAACTTCATG GTGGCGATGG AGACCGGCGG CATGATCGGG 11820

ATAGACTTTG GGCATGCGTT CGGATCCGCT ACGCAGTTTC TGCCGATTCC CGAGTTGATG 11880

CCTTTTCGGC TAACTCGCCA GTTTATCAAT CTGATGTTAC CAATGAAAGA AATGGGCCTT 11940

ATGTACAGCG TCATGGTACA CGCGCTCCGG GCCTTCCGCT CAGACCCTGG CCTGCTCACC 12000

AACACCATGG ATGTGTTTGT GAAGGATCCC TCCTTTGACT GGAAAAATTT TGAACAAAAA 12060

ATGCTGAAAA AAGGAGGATC ATGGATTCAA GACATAAACG TTGCTGAAAA AAATTGGTAT 12120

CCCCGACAGA AAATATGTTA CGCTAAGAGG AAGTTAGCAG GTGCCAATCC AGCAGTCATT 12180

ACTTGTGATG AGCTACTTCT GGGCCACGAG AAGGCACCTG CCTTCAGAGA CTATGTGGCT 12240

GTGGCACGAG GAAGCAAAGA TCACAACATT CGTGCCCGAG AACCAGAGGG TGGGCTTTCA 12300

GAAGAGACTC AAGTGAAGTG CTTGATGGAC CAGGCAACAG ACCCCAACAT CCTTGGCAGA 12360

ACCTGGGAAG GATGGGAGCC CTGGATGTGA 12390

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         iagfderv+++as ++pk++++rG+d+ e+p+Lvkg eDlrqd+rv+qlf+++N +La d

Q: 3720  IAGFDERVTVMASMRRPKRIIIRGHDETEHPFLVKGGEDLRQDQRVEQLFQVMNGILAGD  3779

         89**********************************************************

S: 61    ketsrrkLkirtykVvplstrsgliewventvsLkellkkl..vekkavlldqpi..syr  116

         +++s+r+L++rty+Vvp+++r+gliew+entv+Lk+ll ++  +e+ka++l++p+   ++

Q: 3780  SACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTmsQEEKAAYLSDPKapLCE  3839

         ***************************************998999*********9999**

S: 117   ykdlstvqarkpklkhlkls.........levfkevlenlvpkdllkklllekfpspeew  167

         y d+ t+++ k+++ +++l+         +++f++++++ vp+dllk++++++++sp+ +

Q: 3840  YRDWLTKMSGKHDVGAYMLMykganrtetVTSFRKRESK-VPADLLKRAFVRMSTSPQTF  3898

         ***************************************.********************

S: 168   felrkaytrslAvislvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpe  227

         ++lr+++++s+A+i+++++iLg+gdrhl+n+++++etg ++ idfg+af++a+++l++pe

Q: 3899  LALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGMIGIDFGHAFGSATQFLPIPE  3958

         ************************************************************

S: 228   kvPFRLTrnivnalgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkk..  285

          +PFRLTr+++n++ ++++ G++++ ++++lr++r+++  l+++++vf++dp++dwk+

Q: 3959  LMPFRLTRQFINLMLPMKEMGLMYSVMVHALRAFRSDPGLLTNTMDVFVKDPSFDWKNfe  4018

         ************************************************************

S: 286   ....kkktsketeeelaekakaealkikkllskvekaenavatrdllllee  332

             kk++s+++++++aek++++++ki+++++k+++a++av+t+d+lll++

Q: 4019  qkmlKKGGSWIQDINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGH  4069

         **9999****************************************99987

Domain Sequence
(FASTA)

IAGFDERVTV MASMRRPKRI IIRGHDETEH PFLVKGGEDL RQDQRVEQLF QVMNGILAGD 60

SACSQRALQL RTYSVVPMTS RLGLIEWLEN TVTLKDLLLN TMSQEEKAAY LSDPKAPLCE 120

YRDWLTKMSG KHDVGAYMLM YKGANRTETV TSFRKRESKV PADLLKRAFV RMSTSPQTFL 180

ALRSHFASSH ALICISHWIL GIGDRHLNNF MVAMETGGMI GIDFGHAFGS ATQFLPIPEL 240

MPFRLTRQFI NLMLPMKEMG LMYSVMVHAL RAFRSDPGLL TNTMDVFVKD PSFDWKNFEQ 300

KMLKKGGSWI QDINVAEKNW YPRQKICYAK RKLAGANPAV ITCDELLLGH 350

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0003677	; F:DNA binding
GO:0004677	; F:DNA-dependent protein kinase activity
GO:0006303	; P:double-strand break repair via nonhomologous end joining

KEGG

InterPros

IPR016024	; ARM-type_fold.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR012582	; NUC194.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.

Pfam

PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF08163	; NUC194; 1.
PF00454	; PI3_PI4_kinase; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00915	; PI3_4_KINASE_1; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013