EKS-CAJ-00429

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00429

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/WEE	363.8	9.8E-109	212	486	275

Status

Unreviewed

Ensembl Protein

ENSCJAP00000025076

UniProt Accession

F6YIR0;

Protein Name

Protein Synonyms/Alias

Gene Name

WEE2

Gene Synonyms/Alias

WEE2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000013627	ENSCJAP00000025076	ENSCJAT00000026505

Organism

Callithrix jacchus

Functional Description

Protein Length

568

Protein Sequence
(FASTA)

MGDKDTNEPR QKLNFSYCEE ETETEGQKKA QESREASSQT LEKGEVQDSE AKRTPPRTPL 60

SNVHELDTSW EKDKESPDQI LRTPVSHPLT CPETPAQPDS RSKLLPSDSP STPKSMLSRL 120

AISPTGKLLS RGPKHLKLTP APLRDEMTSF ALVNINPFTP ESYRKLFLQS GGKRKIRGDL 180

EEAGPEEGKG GLPAKRCVLR ETNMASRYEK EFLEVEKIGV GEFGSVYKCI KRLDGCVYAI 240

KRSMKTLAEL SSENLALHEV YAHAVLGHHP HVVRYYSSWV EDDHMIIQSE YCNGGSLQAA 300

ISENTKFHKH FQEPKLKDIL LQISLGLKYI HNSGMVHLDI KPSNIFICHK MQSDSSGVIE 360

EVANEADWFL SANVVYKIGD LGHATSISKP EVEEGDSRFL ANEILQEDYR HLPKADIFAL 420

GLTIALAAGA ESLPTNGAAW HHIRKGNFPD VPQELSEDFS SLLKNMIQPD PEQRPSAAAL 480

ASNRVLRPSL GKTEELQQQL NLEKFKTATL ERELREAQQA QSPQGDIHYG DTWISRTHTG 540

SRSTKRLVGG KSARSSSFTS EQLENMKE 568

Nucleotide Sequence
(FASTA)

ATGGGTGACA AAGATACTAA CGAACCAAGA CAGAAATTAA ACTTTTCCTA TTGTGAGGAG 60

GAGACTGAGA CTGAAGGGCA GAAGAAAGCA CAAGAAAGCA GGGAGGCTTC GAGCCAAACC 120

CTAGAGAAAG GTGAAGTGCA GGATTCAGAG GCAAAGCGTA CACCACCTCG GACTCCCCTT 180

AGTAATGTGC ATGAGCTCGA CACATCGTGG GAAAAAGACA AAGAAAGTCC AGATCAGATT 240

CTTAGGACTC CAGTGTCACA CCCTCTCACA TGTCCTGAGA CACCAGCCCA ACCAGACAGC 300

AGGAGCAAGC TGCTACCCAG TGACAGCCCC TCTACTCCCA AAAGCATGCT GAGTCGGTTG 360

GCGATTTCTC CAACAGGGAA GCTTCTCTCC AGAGGCCCCA AGCATTTGAA GCTCACACCT 420

GCTCCCCTCA GGGATGAGAT GACCTCATTT GCTCTGGTCA ATATTAATCC CTTCACTCCA 480

GAGTCCTATA GAAAATTATT CCTTCAATCT GGTGGGAAGA GGAAAATTCG AGGAGATCTT 540

GAGGAAGCTG GTCCAGAGGA AGGCAAGGGA GGGCTGCCTG CCAAGAGATG TGTTTTACGA 600

GAAACCAACA TGGCTTCCCG CTATGAAAAA GAATTCTTGG AGGTAGAAAA AATTGGGGTT 660

GGTGAATTTG GTTCGGTCTA CAAATGCATT AAGAGGCTGG ATGGATGTGT TTATGCAATA 720

AAGCGCTCTA TGAAAACTTT GGCGGAATTA TCAAGCGAGA ATTTGGCTTT GCATGAAGTT 780

TACGCTCATG CAGTGCTTGG GCATCATCCC CATGTGGTAC GTTACTATTC CTCATGGGTG 840

GAAGATGACC ACATGATCAT TCAGAGTGAA TACTGCAATG GTGGGAGTTT GCAAGCTGCT 900

ATATCTGAGA ACACTAAGTT TCACAAACAT TTCCAAGAGC CAAAACTCAA GGACATCCTT 960

CTACAGATTT CCCTTGGACT AAAGTACATT CACAACTCTG GCATGGTACA CCTGGACATC 1020

AAACCTAGTA ATATTTTCAT TTGTCACAAG ATGCAAAGTG ACTCCTCTGG AGTCATAGAA 1080

GAAGTTGCAA ATGAAGCTGA TTGGTTTCTC TCTGCCAATG TGGTGTATAA AATTGGTGAC 1140

CTGGGCCATG CAACATCAAT AAGTAAACCA GAAGTGGAGG AAGGAGATAG TCGCTTCCTG 1200

GCTAATGAGA TTTTGCAAGA GGATTACCGG CACCTTCCCA AAGCAGACAT ATTTGCCTTG 1260

GGATTAACAA TTGCACTGGC TGCAGGGGCA GAGTCATTAC CCACCAATGG TGCTGCATGG 1320

CACCATATCC GCAAGGGTAA CTTTCCAGAC GTCCCTCAGG AGCTCTCAGA AGACTTTTCC 1380

AGTCTGCTCA AGAACATGAT CCAGCCTGAT CCTGAACAGA GACCTTCTGC AGCAGCTCTT 1440

GCCAGTAATC GAGTCCTCCG GCCTTCCCTG GGAAAAACAG AAGAGCTCCA ACAGCAGCTA 1500

AATTTGGAAA AGTTCAAGAC AGCCACACTG GAAAGGGAAC TGAGAGAAGC CCAGCAGGCC 1560

CAGTCACCCC AGGGAGACAT CCATTATGGT GACACTTGGA TCTCTAGGAC CCACACAGGA 1620

TCAAGAAGCA CAAAACGCCT GGTGGGAGGA AAGAGTGCAA GGTCTTCAAG CTTTACCTCA 1680

GAACAGCTGG AGAACATGAA GGAA 1704

Domain Profile

S: 1     FeevekiGkGefgevfkvvkredgklyAikkskkplkglskekkalrEvtahavlgqhen  60

         F evekiG+Gefg+v+k++kr+dg++yAik+s+k+l++ls+e+ al+Ev+ahavlg+h++

Q: 212   FLEVEKIGVGEFGSVYKCIKRLDGCVYAIKRSMKTLAELSSENLALHEVYAHAVLGHHPH  271

         889*********************************************************

S: 61    vvryisaWeeddslyiqtElCeggsLeaalqeceakkkaleeaelkkilldlllglrylH  120

         vvry+s+W edd+++iq E+C+ggsL+aa++e+++ +k+++e +lk+ill+++lgl+y+H

Q: 272   VVRYYSSWVEDDHMIIQSEYCNGGSLQAAISENTKFHKHFQEPKLKDILLQISLGLKYIH  331

         ************************************************************

S: 121   ssslvHlDikpenifi.......................tkevtlklgDlGlvtelnsed  157

         +s +vHlDikp+nifi                       +++v++k+gDlG++t++   +

Q: 332   NSGMVHLDIKPSNIFIchkmqsdssgvieevaneadwflSANVVYKIGDLGHATSI---S  388

         ********************************************************...*

S: 158   kskveEGDsrylakEilqeeyskl.kaDiFslgltilevaanvelPsnGeaWhklRkgkl  216

         k++veEGDsr+la+Eilqe+y++l kaDiF+lglti+ +a++++lP+nG aWh++Rkg++

Q: 389   KPEVEEGDSRFLANEILQEDYRHLpKADIFALGLTIALAAGAESLPTNGAAWHHIRKGNF  448

         ************************************************************

S: 217   pdeilkelsedlrellklmlepdperRptaeellkhevl  255

         p ++ +elsed+++llk+m++pdpe+Rp+a++l++++vl

Q: 449   P-DVPQELSEDFSSLLKNMIQPDPEQRPSAAALASNRVL  486

         *.9*******************************99875

Domain Sequence
(FASTA)

FLEVEKIGVG EFGSVYKCIK RLDGCVYAIK RSMKTLAELS SENLALHEVY AHAVLGHHPH 60

VVRYYSSWVE DDHMIIQSEY CNGGSLQAAI SENTKFHKHF QEPKLKDILL QISLGLKYIH 120

NSGMVHLDIK PSNIFICHKM QSDSSGVIEE VANEADWFLS ANVVYKIGDL GHATSISKPE 180

VEEGDSRFLA NEILQEDYRH LPKADIFALG LTIALAAGAE SLPTNGAAWH HIRKGNFPDV 240

PQELSEDFSS LLKNMIQPDP EQRPSAAALA SNRVL 275

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004715	; F:non-membrane spanning protein tyrosine kinase activity
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007067	; P:mitosis

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR017164	; Wee1-like_protein_kinase.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013