EKS-CAJ-00331

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00331

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	326.7	2.3E-97	80	327	248

Status

Unreviewed

Ensembl Protein

ENSCJAP00000045698

UniProt Accession

F7AWJ1;

Protein Name

Protein Synonyms/Alias

Gene Name

PAK4

Gene Synonyms/Alias

PAK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000014040	ENSCJAP00000043350	ENSCJAT00000060767
ENSCJAG00000014040	ENSCJAP00000025829	ENSCJAT00000027295
ENSCJAG00000014040	ENSCJAP00000025832	ENSCJAT00000027298
ENSCJAG00000014040	ENSCJAP00000045698	ENSCJAT00000053833
ENSCJAG00000014040	ENSCJAP00000046662	ENSCJAT00000057180

Organism

Callithrix jacchus

Functional Description

Protein Length

346

Protein Sequence
(FASTA)

TTWPLMGHQR VAWPSPSPPP PPGLPPESEA PPALECWAPM PRSPRSPQRE PQRVSHEQFR 60

AALQLVVDPG DPRSYLDNFI KIGEGSTGIV CIATVRSSGK LVAVKKMDLR KQQRRELLFN 120

EVVIMRDYQH ENVVEMYNSY LVGDELWVVM EFLEGGALTD IVTHTRMNEE QIAAVCLAVL 180

QALSVLHAQG VIHRDIKSDS ILLTHDGRVK LSDFGFCAQV SKEVPRRKSL VGTPYWMAPE 240

LISRLPYGPE VDIWSLGIMV IEMVDGEPPY FNEPPLKAMK MIRDNLPPRL KNLHKVSPSL 300

KGFLDRLLVR DPTQRATAAE LLKHPFLAKA GPPASIVPLM RQNRTR 346

Nucleotide Sequence
(FASTA)

ACGACGTGGC CCCTAATGGG CCATCAGCGG GTGGCCTGGC CGTCCCCCAG TCCTCCTCCT 60

CCTCCCGGCC TCCCGCCCGA GTCCGAGGCG CCCCCAGCCC TGGAGTGCTG GGCCCCCATG 120

CCTCGGAGCC CCCGCTCACC ACAGCGGGAG CCACAGCGCG TATCACATGA GCAGTTCCGG 180

GCTGCCCTGC AGCTGGTGGT GGACCCGGGC GACCCCCGAT CCTACCTGGA CAACTTCATC 240

AAGATTGGCG AGGGCTCCAC GGGCATCGTG TGCATCGCCA CCGTGCGCAG CTCAGGCAAG 300

CTGGTGGCTG TCAAGAAGAT GGACCTGCGC AAGCAGCAGA GGCGTGAGCT GCTCTTCAAC 360

GAGGTGGTGA TCATGCGGGA CTATCAGCAT GAGAACGTGG TGGAGATGTA CAACAGCTAC 420

TTGGTGGGGG ACGAGCTCTG GGTGGTCATG GAGTTCCTGG AAGGAGGAGC CCTCACCGAC 480

ATTGTCACGC ACACCAGGAT GAACGAGGAA CAGATCGCAG CCGTGTGCCT GGCAGTGCTG 540

CAGGCCCTAT CGGTGCTTCA TGCCCAGGGC GTCATCCACC GGGACATCAA GAGCGACTCG 600

ATCCTGCTGA CCCATGATGG CAGGGTGAAG CTGTCAGACT TCGGGTTCTG CGCCCAGGTG 660

AGCAAGGAAG TGCCCCGGAG GAAGTCGCTG GTCGGCACGC CCTACTGGAT GGCCCCAGAG 720

CTCATCTCCC GACTTCCCTA CGGGCCAGAG GTGGATATCT GGTCACTGGG GATAATGGTG 780

ATCGAGATGG TGGACGGAGA GCCCCCCTAC TTTAACGAGC CACCCCTCAA AGCCATGAAG 840

ATGATTCGGG ACAACCTGCC GCCCCGACTG AAGAACCTAC ACAAGGTGTC GCCTTCCCTG 900

AAGGGCTTCC TGGACCGCCT CCTGGTGCGG GACCCCACTC AGCGGGCTAC GGCTGCCGAG 960

CTGCTGAAGC ACCCATTCCT GGCCAAGGCG GGACCCCCTG CCAGCATCGT ACCCCTCATG 1020

CGCCAGAACC GCACCAGATG A 1041

Domain Profile

S: 5     eeigkGalgkvylarekktgelvaikkinlekqekleelqkeisvlkklkhpniveyles  64

          +ig+G++g v++a+ +++g+lva+kk++l+kq++ e+l++e+ ++++++h+n+ve+++s

Q: 80    IKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNS  139

         68**********************************************************

S: 65    flkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkviHrdi  124

         +l+ +elw+vme+l+gG+l+d+v+   +++++Eeqia+++  vl+aL+ lH+++viHrdi

Q: 140   YLVGDELWVVMEFLEGGALTDIVT---HTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDI  196

         ************************...9********************************

S: 125   kakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqeekgYdekaDiw  184

         k+++iLlt++g+VkLsdfg++aq++k++ +rk++vgtpywmAPE+i+  +  Y  ++Diw

Q: 197   KSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELIS--RLPYGPEVDIW  254

         ***********************************************..9**********

S: 185   slGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekclqknpek  244

         slGI++ie+++gepP+++++plka+ +i +n pp+lk+ +k+s+++k f++++l ++p +

Q: 255   SLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPTQ  314

         ************************************************************

S: 245   RpsasellkhkFl  257

         R++a+ellkh+Fl

Q: 315   RATAAELLKHPFL  327

         ************7

Domain Sequence
(FASTA)

IKIGEGSTGI VCIATVRSSG KLVAVKKMDL RKQQRRELLF NEVVIMRDYQ HENVVEMYNS 60

YLVGDELWVV MEFLEGGALT DIVTHTRMNE EQIAAVCLAV LQALSVLHAQ GVIHRDIKSD 120

SILLTHDGRV KLSDFGFCAQ VSKEVPRRKS LVGTPYWMAP ELISRLPYGP EVDIWSLGIM 180

VIEMVDGEPP YFNEPPLKAM KMIRDNLPPR LKNLHKVSPS LKGFLDRLLV RDPTQRATAA 240

ELLKHPFL 248

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000095	; PAK_box_Rho-bd.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00786	; PBD; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00285	; PBD; 1.
SM00220	; S_TKc; 1.

Prosites

PS50108	; CRIB; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013