EPS-CAJ-00128

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-CAJ-00128

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPP/PP7	278.0	1.8E-82	131	333	203

Status

Unreviewed

Ensembl Protein

ENSCJAP00000026393

UniProt Accession

F7HXK0;

Protein Name

Serine/threonine-protein phosphatase

Protein Synonyms/Alias

Gene Name

PPEF2

Gene Synonyms/Alias

PPEF2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000014333	ENSCJAP00000026429	ENSCJAT00000027935
ENSCJAG00000014333	ENSCJAP00000026393	ENSCJAT00000027895

Organism

Callithrix jacchus

Functional Description

Protein Length

597

Protein Sequence
(FASTA)

MGSGTSTQHH FAFQNAERAF KAAALIQRWY RRYMARLEMR RRCTWSIFQS IEYAGQQDQV 60

KLHGFFSYLM DHFTPSSHNE RDFLTRIFTE ERFAQDSKME KCSDYESIEV PDSYRGPHLS 120

FPLLPDHATA LVEAFRLKQQ LHARYVLNLL YETKKHLVQL PNINRVSTCY SEEITVCGDL 180

HGQLDDLIFI FYKNGLPSPE RSYVFNGDFV DRGKDSVEIL MILFAFMLVY PKEFHLNRGN 240

HEDHMVNLRY GFTKEVMNKY KIHGKEILRT LKDVFCWLPL ATLIDEKVLI LHGGVSDITD 300

LEILDKIERC KIVSIMRYKT RQKSEKQMEE QRKANQKSSA QGPIPWFLPQ SRSLPSSPLR 360

LGPYKAHKSS RSSSIPCGGS LDGQELSQQV RSSVELELER CRQQAGLLVT EEKEEPSGSA 420

SETDSDTGEL RKPTQEEWRQ VVDILWSDPM AQEGCKANTI RGGGCYFGPD VTEQLLQKYN 480

LQFLIRSHEC KPEGYEFCHN RKVLTIFSAS NYYEVGSNRG AYVKLGPALT PHIVQYQRQV 540

THTLTMRQRI SRVEESALRA LREKLFAHSS DLLIEFKKHD VDKVGLASSQ LCHYQQK 597

Nucleotide Sequence
(FASTA)

ATGGGAAGCG GCACCTCCAC CCAACATCAT TTTGCTTTCC AGAATGCAGA GAGAGCCTTC 60

AAGGCAGCAG CCCTGATCCA GAGATGGTAC CGGCGCTATA TGGCCCGCCT GGAGATGAGG 120

CGGCGTTGCA CCTGGAGCAT CTTCCAGTCT ATAGAATACG CTGGGCAGCA AGACCAAGTC 180

AAGCTCCATG GTTTCTTCAG CTATCTCATG GATCACTTCA CCCCCAGCAG CCACAACGAG 240

AGGGACTTCC TCACCCGAAT ATTCACTGAG GAGAGATTCG CCCAGGACTC CAAGATGGAG 300

AAATGCAGTG ACTATGAGTC CATAGAGGTA CCCGACAGTT ACAGGGGACC ACACCTCTCC 360

TTCCCGCTCC TGCCTGACCA TGCTACTGCC CTGGTAGAAG CATTCAGACT GAAACAACAG 420

CTCCACGCTC GCTACGTCTT GAACCTTTTG TATGAAACCA AGAAACATCT GGTACAGCTG 480

CCAAACATCA ACCGGGTTTC AACCTGTTAC AGTGAGGAGA TCACAGTGTG TGGAGATTTA 540

CATGGCCAAT TGGATGACTT AATATTTATA TTTTATAAGA ACGGCCTCCC ATCGCCAGAA 600

CGGTCATACG TGTTCAACGG TGACTTTGTG GATCGAGGCA AGGATTCAGT AGAGATCCTG 660

ATGATTCTTT TTGCCTTCAT GCTGGTTTAC CCCAAAGAGT TCCATCTTAA CAGAGGAAAC 720

CATGAGGACC ATATGGTGAA CTTACGATAC GGCTTCACCA AGGAAGTGAT GAATAAATAC 780

AAGATACATG GCAAGGAAAT ACTAAGAACC CTGAAAGACG TTTTCTGTTG GCTTCCGCTG 840

GCCACTCTGA TAGACGAGAA AGTTCTAATT CTTCATGGTG GGGTGTCAGA CATAACTGAT 900

CTGGAGATTT TGGACAAAAT AGAGAGGTGC AAGATAGTTT CCATCATGAG GTACAAAACG 960

AGACAGAAGA GTGAGAAGCA GATGGAGGAG CAGAGAAAAG CCAACCAGAA GAGCTCCGCA 1020

CAGGGACCCA TCCCATGGTT TCTCCCCCAA AGCCGCTCTC TTCCCTCTTC CCCCCTTCGT 1080

CTGGGCCCCT ACAAGGCTCA CAAAAGCAGC AGGTCCTCCA GCATCCCCTG TGGCGGATCC 1140

CTGGATGGGC AGGAGCTCTC CCAGCAGGTG CGGAGCTCCG TGGAACTGGA GCTGGAGCGG 1200

TGCCGGCAGC AAGCAGGCCT CCTGGTGACC GAGGAGAAAG AGGAGCCCTC GGGCTCGGCC 1260

TCAGAAACAG ACTCTGACAC CGGAGAGCTG CGGAAGCCCA CTCAGGAGGA GTGGAGGCAG 1320

GTTGTAGACA TCCTGTGGAG TGATCCCATG GCTCAAGAGG GCTGCAAGGC CAACACCATT 1380

CGAGGAGGAG GCTGTTATTT TGGGCCTGAT GTGACAGAAC AGTTGCTACA AAAATACAAT 1440

CTGCAATTCC TGATCCGTTC ACACGAATGC AAACCCGAAG GCTATGAATT CTGTCACAAC 1500

CGCAAGGTAT TAACCATCTT TTCTGCCTCC AACTACTATG AAGTTGGCAG CAACAGAGGG 1560

GCCTATGTCA AACTGGGGCC AGCCCTGACC CCACATATCG TGCAGTATCA GCGACAGGTG 1620

ACCCACACAC TCACCATGAG GCAAAGGATT AGCAGAGTGG AGGAGTCGGC TCTGAGAGCT 1680

CTGCGGGAGA AGCTGTTTGC TCATTCTTCA GATCTTCTCA TCGAATTTAA GAAGCATGAT 1740

GTAGATAAAG TCGGCCTAGC TTCCAGCCAA CTCTGCCACT ACCAACAAAA ATAG 1794

Domain Profile

S: 4     llevfkkkrilhakyvlevlfeakkvlkqlpnishvstavskevtvvGdlhGklddlllv  63

         l+e+f+ k++lha+yvl++l+e+kk l qlpni++vst+ s+e+tv+GdlhG+lddl+++

Q: 131   LVEAFRLKQQLHARYVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFI  190

         89**********************************************************

S: 64    lkknGlPsernpyvfnGdfvdrGkrglevllvllslflvfPnavylnrGnhedkvmnary  123

         ++knGlPs +++yvfnGdfvdrGk ++e+l++l +++lv+P++ +lnrGnhed+++n+ry

Q: 191   FYKNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRY  250

         ************************************************************

S: 124   GfekevlskykrkgkrilrileevyewlPlgsivdsrvlvvhGGlsestsldllksverk  183

         Gf+kev++kyk +gk ilr+l++v+ wlPl++++d++vl++hGG+s+ t+l+ l ++er

Q: 251   GFTKEVMNKYKIHGKEILRTLKDVFCWLPLATLIDEKVLILHGGVSDITDLEILDKIERC  310

         ************************************************************

S: 184   krksvllpPeessrdlgrldtdge  207

         k +s+++  +  +    +++++ +

Q: 311   KIVSIMRYKTRQK-SEKQMEEQRK  333

         ******9887433.3334444444

Domain Sequence
(FASTA)

LVEAFRLKQQ LHARYVLNLL YETKKHLVQL PNINRVSTCY SEEITVCGDL HGQLDDLIFI 60

FYKNGLPSPE RSYVFNGDFV DRGKDSVEIL MILFAFMLVY PKEFHLNRGN HEDHMVNLRY 120

GFTKEVMNKY KIHGKEILRT LKDVFCWLPL ATLIDEKVLI LHGGVSDITD LEILDKIERC 180

KIVSIMRYKT RQKSEKQMEE QRK 203

Keyword

Calcium; Complete proteome; Hydrolase; Iron; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005509	; F:calcium ion binding
GO:0005506	; F:iron ion binding
GO:0030145	; F:manganese ion binding
GO:0004721	; F:phosphoprotein phosphatase activity
GO:0050906	; P:detection of stimulus involved in sensory perception

KEGG

InterPros

IPR011992	; EF-hand-like_dom.
IPR018247	; EF_Hand_1_Ca_BS.
IPR018249	; EF_HAND_2.
IPR002048	; EF_hand_Ca-bd.
IPR000048	; IQ_motif_EF-hand-BS.
IPR004843	; Metallo_PEstase_dom.
IPR013235	; PPP_dom.
IPR012008	; Ser/Thr-Pase_EF-hand_contain.
IPR006186	; Ser/Thr-sp_prot-phosphatase.

Pfam

PF00149	; Metallophos; 1.
PF08321	; PPP5; 1.

SMARTs

SM00054	; EFh; 2.
SM00015	; IQ; 1.
SM00156	; PP2Ac; 1.

Prosites

PS00018	; EF_HAND_1; 2.
PS50222	; EF_HAND_2; 3.
PS50096	; IQ; 1.
PS00125	; SER_THR_PHOSPHATASE; 1.

Prints

PR00114

; STPHPHTASE.

Created Date

20-Feb-2013