EKS-CAJ-00251

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAJ-00251

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	334.5	7.4E-100	50	301	252

Status

Unreviewed

Ensembl Protein

ENSCJAP00000027549

UniProt Accession

F7DDD3;

Protein Name

Protein Synonyms/Alias

Gene Name

NUAK1

Gene Synonyms/Alias

NUAK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCJAG00000014948	ENSCJAP00000027549	ENSCJAT00000029120
ENSCJAG00000014948	ENSCJAP00000027550	ENSCJAT00000029121

Organism

Callithrix jacchus

Functional Description

Protein Length

656

Protein Sequence
(FASTA)

MEGATAPVAG DRPDPGPGAL GSPATAAAPE PRKPHGVKRH HHKHNLKHRY ELQETLGKGT 60

YGKVKRATER FSGRVVAIKS IRKDKIKDEQ DMVHIRREIE IMSSLNHPHI ISIYEVFENK 120

DKIVIIMEYA SKGELYDYIS ERRRLSERET RHFFRQIVSA VHYCHKNGVV HRDLKLENIL 180

LDDNCNIKIA DFGLSNLYQK DKFLQTFCGS PLYASPEIVN GRPYRGPEVD SWALGVLLYT 240

LVYGTMPFDG FDHKNLIRQI SSGEYREPTQ PSDARGLIRW MLMVNPDRRA TIEDIANHWW 300

VNWGYKSSVC DCDALHDSES PLLARIIDWH HRSTGLQADA DAKMKGLAKP ATSEVMLERQ 360

RSLKKSKKEN DFAQSGQDAV PESPSKLSSK RPKGILKKRS NSEHRSHSTG FIEGVVGPTL 420

PSTFKMEQDL CRTGVLLPSS PEAEVPGKLS PKQSATMPKK GILKKTQQRE SGYYSSPERS 480

ESSELLDSND VMGSSIPSPS PPDPARVTSH SLSCRRKGIL KHSSKYSAGA MDPALVSPEM 540

PTLESLSEPG VPAEGLSRSY SRPSSVISDD SVLSSDSFDL LDLQENRPAR QCIRSCVSAE 600

NFLQIQDFEG LQNRPRPQYL KRYRNRGADS SFSLLTDMDD VTQVYKQALE ICSKLN 656

Nucleotide Sequence
(FASTA)

ATGGAAGGGG CCACTGCGCC CGTGGCGGGG GACCGTCCGG ATCCGGGGCC GGGGGCTCTG 60

GGCTCCCCCG CGACGGCGGC AGCCCCGGAG CCCAGGAAGC CGCACGGGGT GAAGCGGCAT 120

CACCACAAGC ACAACTTGAA GCACCGCTAC GAGCTGCAGG AGACCCTGGG CAAAGGCACC 180

TACGGCAAAG TCAAGAGGGC CACTGAGAGG TTTTCGGGCC GAGTGGTTGC TATAAAATCC 240

ATTCGTAAGG ACAAAATTAA GGATGAACAA GACATGGTTC ACATCAGACG AGAGATTGAG 300

ATCATGTCAT CTCTCAACCA TCCTCATATC ATCAGTATTT ATGAAGTGTT TGAGAACAAA 360

GATAAGATTG TGATCATCAT GGAATATGCA AGCAAAGGGG AGCTGTATGA TTACATCAGC 420

GAGCGGCGGC GCCTCAGTGA GAGGGAGACC CGGCACTTCT TCCGGCAGAT CGTCTCCGCC 480

GTGCACTATT GTCATAAGAA CGGTGTGGTC CACCGGGACT TGAAGCTGGA AAATATACTG 540

CTTGATGACA ACTGCAATAT TAAGATTGCT GACTTTGGGC TTTCCAACCT GTACCAGAAG 600

GATAAGTTCC TGCAAACGTT TTGCGGGAGT CCACTCTATG CATCTCCTGA GATTGTCAAT 660

GGGAGACCTT ACCGAGGACC AGAGGTGGAC AGCTGGGCCC TGGGCGTGTT GCTTTACACC 720

CTCGTTTATG GAACAATGCC CTTCGATGGT TTCGATCACA AAAACCTCAT TCGTCAGATC 780

AGCAGCGGAG AGTACCGGGA GCCCACGCAG CCCTCAGATG CTCGAGGACT CATTCGGTGG 840

ATGCTGATGG TGAACCCTGA TCGTCGGGCC ACTATTGAGG ACATTGCCAA CCACTGGTGG 900

GTGAACTGGG GCTATAAGAG CAGCGTATGT GACTGCGATG CCCTCCATGA CTCTGAGTCC 960

CCACTCCTGG CTCGGATCAT TGACTGGCAC CACCGTTCCA CAGGGCTGCA GGCTGATGCC 1020

GATGCCAAAA TGAAGGGCCT GGCCAAGCCT GCAACATCTG AGGTCATGCT AGAGCGGCAG 1080

CGGTCACTGA AGAAATCCAA GAAAGAGAAT GACTTTGCCC AGTCTGGTCA GGATGCAGTG 1140

CCTGAAAGCC CATCCAAGTT GAGTTCCAAG AGGCCCAAGG GGATCCTGAA GAAGCGAAGT 1200

AACAGCGAGC ATCGCTCTCA CAGCACTGGC TTCATCGAAG GCGTGGTTGG TCCTACCTTA 1260

CCCTCTACTT TCAAGATGGA GCAGGACTTA TGCAGGACTG GTGTGCTCCT CCCAAGCTCA 1320

CCAGAGGCAG AGGTGCCCGG AAAACTCAGC CCCAAGCAGT CAGCCACGAT GCCCAAGAAA 1380

GGCATCTTGA AAAAGACCCA GCAAAGAGAA TCGGGTTACT ACTCTTCCCC AGAGCGCAGC 1440

GAGTCTTCGG AGCTGTTGGA CAGCAATGAT GTGATGGGTA GCAGCATCCC TTCCCCCAGC 1500

CCCCCGGACC CAGCCAGGGT GACCTCCCAT AGTCTCTCCT GCCGGAGGAA GGGCATCTTG 1560

AAACACAGCA GCAAGTACTC AGCGGGTGCC ATGGACCCTG CCCTGGTCAG CCCTGAAATG 1620

CCCACACTGG AATCCCTGTC AGAGCCTGGC GTCCCTGCTG AGGGCCTCTC CCGGAGCTAT 1680

AGCCGTCCTT CCAGTGTCAT CAGCGATGAC AGCGTGCTGT CCAGTGACTC TTTCGACTTA 1740

CTGGATTTGC AGGAGAATCG CCCTGCCCGC CAGTGCATCC GCAGCTGCGT CTCTGCAGAA 1800

AATTTCCTCC AGATCCAGGA CTTTGAGGGG CTCCAGAACC GGCCCCGGCC CCAGTACCTG 1860

AAGCGGTACC GGAACCGGGG GGCAGACAGC AGCTTCTCCC TCCTCACAGA CATGGATGAC 1920

GTGACTCAGG TCTACAAGCA AGCGCTGGAG ATCTGCAGCA AGCTCAACTA G 1971

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y+l++tlG+g++gkVk a+++  ++ va+K i+k+k+ +e+ + +i+rEiei+++l+hp+

Q: 50    YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIkDEQDMVHIRREIEIMSSLNHPH  109

         99**********************************95667788****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         ii+++ev+e+k+k+++++eyas+geL+dyi+e++rl+e+e+r++f+q+vsav+Y+h++g+

Q: 110   IISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGV  169

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkv  179

         vHrDlK+eN+lld++ nikiaDFGl+nl++++k l+tfcGsp Ya+Pe+++g++Y+gp+v

Q: 170   VHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEV  229

         ************************************************************

S: 180   DvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpek  239

         D W+lGv+Ly+lv+g++Pfd+ + k+l ++i++g+++ p++  ++++ L+r +L+v+p++

Q: 230   DSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQ-PSDARGLIRWMLMVNPDR  288

         ***************************************99.7789**************

S: 240   Ratieeilkhewl  252

         Ratie+i +h w+

Q: 289   RATIEDIANHWWV  301

         ************6

Domain Sequence
(FASTA)

YELQETLGKG TYGKVKRATE RFSGRVVAIK SIRKDKIKDE QDMVHIRREI EIMSSLNHPH 60

IISIYEVFEN KDKIVIIMEY ASKGELYDYI SERRRLSERE TRHFFRQIVS AVHYCHKNGV 120

VHRDLKLENI LLDDNCNIKI ADFGLSNLYQ KDKFLQTFCG SPLYASPEIV NGRPYRGPEV 180

DSWALGVLLY TLVYGTMPFD GFDHKNLIRQ ISSGEYREPT QPSDARGLIR WMLMVNPDRR 240

ATIEDIANHW WV 252

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013